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dipyridamole and Aging

dipyridamole has been researched along with Aging in 17 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
" SMI was assessed by either exercise or dipyridamole single-photon emission-computed tomography myocardial perfusion imaging with thallium-201."3.73Predictive value of silent myocardial ischemia for cardiac events in diabetic patients: influence of age in a French multicenter study. ( Attali, JR; Brulport-Cerisier, V; Cosson, E; Estour, B; Halimi, S; Lormeau, B; Maréchaud, R; Pariès, J; Sachs, RN; Torremocha, F; Valensi, P; Vanzetto, G, 2005)
"MBF was quantified by positron emission tomography with oxygen-15-labeled water at baseline and during hyperemia induced by either adenosine or dipyridamole in 131 men and 38 women, aged 21-86 (mean 46+/-12) years."3.71Heterogeneity of resting and hyperemic myocardial blood flow in healthy humans. ( Camici, PG; Chareonthaitawee, P; Kaufmann, PA; Rimoldi, O, 2001)
" For stress imaging, a bicycle protocol was used in 79 of the patients and a dipyridamole protocol in 23."3.71Age- and gender-specific differences in left ventricular cardiac function and volumes determined by gated SPET. ( De Backer, G; De Bondt, P; De Sutter, J; De Winter, F; Dierckx, RA; Van de Wiele, C, 2001)
"Aging does not alter significantly dipyridamole-induced hyperemic flows; although coronary vascular resistance after dipyridamole was somewhat increased in older subjects."3.68Influence of age and hemodynamics on myocardial blood flow and flow reserve. ( Brunken, RC; Chan, A; Chan, S; Chen, K; Czernin, J; Krivokapich, J; Müller, P; Phelps, ME; Porenta, G; Schelbert, HR, 1993)

Research

Studies (17)

TimeframeStudies, this research(%)All Research%
pre-19904 (23.53)18.7374
1990's8 (47.06)18.2507
2000's5 (29.41)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Valensi, P1
Pariès, J1
Brulport-Cerisier, V1
Torremocha, F1
Sachs, RN1
Vanzetto, G1
Cosson, E1
Lormeau, B1
Attali, JR1
Maréchaud, R1
Estour, B1
Halimi, S1
Bai, J1
Hashimoto, J1
Nakahara, T1
Suzuki, T1
Kubo, A1
Tornling, G1
Unge, G1
Adolfsson, J1
Ljungqvist, A1
Carlsson, S1
Uren, NG1
Camici, PG2
Melin, JA1
Bol, A1
de Bruyne, B1
Radvan, J1
Olivotto, I1
Rosen, SD1
Impallomeni, M1
Wijns, W1
Buxton, DB2
Czernin, J1
Müller, P1
Chan, S1
Brunken, RC1
Porenta, G1
Krivokapich, J1
Chen, K1
Chan, A1
Phelps, ME1
Schelbert, HR1
Cohen, M1
Touzery, C1
Cottin, Y1
Benoit, T1
d'Athis, P1
Roy, S1
Louis, P1
Wolf, JE1
Rigo, P1
Brunotte, F1
Kozàkovà, M1
Galetta, F1
Gregorini, L1
Bigalli, G1
Franzoni, F1
Giusti, C1
Palombo, C1
Chareonthaitawee, P1
Kaufmann, PA1
Rimoldi, O1
De Bondt, P1
Van de Wiele, C1
De Sutter, J1
De Winter, F1
De Backer, G1
Dierckx, RA1
Senneff, MJ1
Geltman, EM1
Bergmann, SR1
Picano, E1
Lattanzi, F1
L'Abbate, A1
Irace, L1
Aiello, C1
Perna, B1
Russo, PE1
Ruggiero, B1
Citro, R1
Iacono, A1
Vigorito, C1
Giordano, A1
Casaburi, E1
Ferraro, P1
Maurelli, B1
Rumolo, S1
Silvestri, P1
Rengo, F1
Deckert, J1
Morgan, PF1
Daval, JL1
Nakajima, T1
Marangos, PJ1
Gerson, MC1
Moore, EN1
Ellis, K1

Other Studies

17 other studies available for dipyridamole and Aging

ArticleYear
Predictive value of silent myocardial ischemia for cardiac events in diabetic patients: influence of age in a French multicenter study.
    Diabetes care, 2005, Volume: 28, Issue:11

    Topics: Aging; Algorithms; Chi-Square Distribution; Cholesterol, HDL; Cohort Studies; Diabetes Mellitus; Dia

2005
Influence of ageing on perioperative cardiac risk in non-cardiac surgery.
    Age and ageing, 2007, Volume: 36, Issue:1

    Topics: Aged; Aged, 80 and over; Aging; Dipyridamole; Humans; Intraoperative Complications; Middle Aged; Mul

2007
Proliferative activity of capillary wall cells in skeletal muscle of rats during long-term treatment with dipyridamole.
    Arzneimittel-Forschung, 1980, Volume: 30, Issue:4

    Topics: Aging; Animals; Autoradiography; Body Weight; Capillaries; Cell Division; Dipyridamole; DNA; Female;

1980
Effect of aging on myocardial perfusion reserve.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:11

    Topics: Adenosine; Adult; Age Factors; Aged; Aged, 80 and over; Aging; Coronary Circulation; Coronary Vessel

1995
Blunted response of myocardial perfusion to dipyridamole in older adults (revisited)
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1995, Volume: 36, Issue:6

    Topics: Adult; Aging; Coronary Circulation; Coronary Disease; Dipyridamole; Humans

1995
Influence of age and hemodynamics on myocardial blood flow and flow reserve.
    Circulation, 1993, Volume: 88, Issue:1

    Topics: Adult; Aged; Aged, 80 and over; Aging; Ammonia; Coronary Circulation; Coronary Vessels; Dipyridamole

1993
Quantitative myocardial thallium single-photon emission computed tomography in normal women: demonstration of age-related differences.
    European journal of nuclear medicine, 1996, Volume: 23, Issue:1

    Topics: Adult; Age Factors; Aged; Aging; Breast; Coronary Disease; Dipyridamole; Exercise Test; Female; Hear

1996
Coronary vasodilator capacity and epicardial vessel remodeling in physiological and hypertensive hypertrophy.
    Hypertension (Dallas, Tex. : 1979), 2000, Volume: 36, Issue:3

    Topics: Adult; Aged; Aging; Analysis of Variance; Bicycling; Blood Flow Velocity; Blood Pressure; Coronary C

2000
Heterogeneity of resting and hyperemic myocardial blood flow in healthy humans.
    Cardiovascular research, 2001, Volume: 50, Issue:1

    Topics: Adenosine; Adult; Aged; Aged, 80 and over; Aging; Coronary Circulation; Dipyridamole; Female; Heart;

2001
Age- and gender-specific differences in left ventricular cardiac function and volumes determined by gated SPET.
    European journal of nuclear medicine, 2001, Volume: 28, Issue:5

    Topics: Adult; Aged; Aging; Algorithms; Body Surface Area; Dipyridamole; Exercise Test; Female; Gated Blood-

2001
Blunted response of myocardial perfusion to dipyridamole in older adults.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1992, Volume: 33, Issue:7

    Topics: Aging; Coronary Circulation; Dipyridamole; Humans

1992
Noninvasive delineation of the effects of moderate aging on myocardial perfusion.
    Journal of nuclear medicine : official publication, Society of Nuclear Medicine, 1991, Volume: 32, Issue:11

    Topics: Adult; Aged; Aging; Dipyridamole; Exercise Test; Female; Heart; Hemodynamics; Humans; Male; Middle A

1991
Present application, practical aspects, and future issues on dipyridamole echocardiography.
    Circulation, 1991, Volume: 83, Issue:5 Suppl

    Topics: Administration, Oral; Aging; Dipyridamole; Echocardiography; Electrocardiography; Exercise Test; For

1991
[Systemic effects of intravenous dipyridamole in patients of various age groups].
    Minerva cardioangiologica, 1990, Volume: 38, Issue:6

    Topics: Adult; Aged; Aging; Dipyridamole; Female; Hemodynamics; Humans; Infusions, Intravenous; Male; Middle

1990
Coronary vascular reserve in elderly subjects.
    Bibliotheca cardiologica, 1989, Issue:44

    Topics: Aged; Aged, 80 and over; Aging; Blood Pressure; Coronary Circulation; Dipyridamole; Heart Rate; Huma

1989
Ontogeny of adenosine uptake sites in guinea pig brain: differential profile of [3H]nitrobenzylthioinosine and [3H]dipyridamole binding sites.
    Brain research, 1988, Aug-01, Volume: 470, Issue:2

    Topics: Aging; Animals; Cerebellum; Cerebral Cortex; Dipyridamole; Gestational Age; Guinea Pigs; Inosine; Ki

1988
Systemic effects and safety of intravenous dipyridamole in elderly patients with suspected coronary artery disease.
    The American journal of cardiology, 1987, Dec-01, Volume: 60, Issue:16

    Topics: Adult; Aged; Aged, 80 and over; Aging; Blood Pressure; Coronary Disease; Dipyridamole; Female; Heart

1987