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dipyridamole and Adverse Drug Event

dipyridamole has been researched along with Adverse Drug Event in 9 studies

Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.

Research Excerpts

ExcerptRelevanceReference
"The safety of fixed-dose combination aspirin-extended-release (ER) dipyridamole for stroke prevention in patients with ischemic heart disease is reviewed."4.86Safety of fixed-dose aspirin-extended-release dipyridamole in patients with ischemic heart disease. ( Crown, N; Mysak, T, 2010)
"Intravenous administration of aminophylline is widely adopted to reverse dipyridamole-related adverse effects (AEs) during stress myocardial perfusion imaging (MPI)."1.40Experience of low-dose aminophylline use to relieve minor adverse effects of dipyridamole in patients undergoing stress myocardial perfusion imaging. ( Cheng, CY; Hou, CH; Ku, CH; Lin, LF; Shen, DH; Tseng, NC, 2014)
"We assessed the safety of thrombolysis under APs in 11,865 patients compliant with the European license criteria and recorded between 2002 and 2007 in the Safe Implementation of Treatments in Stroke (SITS) International Stroke Thrombolysis Register (SITS-ISTR)."1.36Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset. ( Ahmed, N; Diedler, J; Ford, GA; Lees, KR; Luijckx, GJ; Overgaard, K; Ringleb, P; Soinne, L; Sykora, M; Uyttenboogaart, M; Wahlgren, N, 2010)
" Evidence of systemic toxicity was observed in animals dosed chronically with pyrimethamine or amiloride, but no skin papillomas were observed in mice treated with amiloride, dipyridamole, or pyrimethamine for 26 weeks."1.32Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components. ( Lin, KK; Rosenzweig, BA; Sistare, FD; Thompson, KL; Weaver, JL; Zhang, J, 2003)

Research

Studies (9)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (22.22)29.6817
2010's7 (77.78)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Pedersen, JM1
Matsson, P1
Bergström, CA1
Norinder, U1
Hoogstraate, J1
Artursson, P1
Liu, Z1
Shi, Q1
Ding, D1
Kelly, R1
Fang, H1
Tong, W1
Morgan, RE1
van Staden, CJ1
Chen, Y1
Kalyanaraman, N1
Kalanzi, J1
Dunn, RT1
Afshari, CA1
Hamadeh, HK1
Lin, LF1
Cheng, CY1
Hou, CH1
Ku, CH1
Tseng, NC1
Shen, DH1
Massalha, S1
Reizberg, I1
Israel, O1
Kapeliovich, M1
Sholy, H1
Koskosi, A1
Keidar, Z1
Marai, I1
Diedler, J1
Ahmed, N1
Sykora, M1
Uyttenboogaart, M1
Overgaard, K1
Luijckx, GJ1
Soinne, L1
Ford, GA1
Lees, KR1
Wahlgren, N1
Ringleb, P1
Crown, N1
Mysak, T1
Sanfiorenzo, C1
Pipet, A1
Thompson, KL1
Rosenzweig, BA1
Weaver, JL1
Zhang, J1
Lin, KK1
Sistare, FD1

Reviews

2 reviews available for dipyridamole and Adverse Drug Event

ArticleYear
Safety of fixed-dose aspirin-extended-release dipyridamole in patients with ischemic heart disease.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2010, May-01, Volume: 67, Issue:9

    Topics: Aspirin; Aspirin, Dipyridamole Drug Combination; Dipyridamole; Drug Combinations; Drug-Related Side

2010
[Exacerbations of asthma--precipitating factors: drugs].
    Revue des maladies respiratoires, 2011, Volume: 28, Issue:8

    Topics: Adrenergic beta-Antagonists; Anti-Inflammatory Agents, Non-Steroidal; Asthma; Contraindications; Dip

2011

Other Studies

7 other studies available for dipyridamole and Adverse Drug Event

ArticleYear
Prediction and identification of drug interactions with the human ATP-binding cassette transporter multidrug-resistance associated protein 2 (MRP2; ABCC2).
    Journal of medicinal chemistry, 2008, Jun-12, Volume: 51, Issue:11

    Topics: Administration, Oral; Animals; Antineoplastic Agents; Antipsychotic Agents; Antiviral Agents; ATP Bi

2008
Translating clinical findings into knowledge in drug safety evaluation--drug induced liver injury prediction system (DILIps).
    PLoS computational biology, 2011, Volume: 7, Issue:12

    Topics: Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Chemical and Drug Induced Liver Injury; Da

2011
A multifactorial approach to hepatobiliary transporter assessment enables improved therapeutic compound development.
    Toxicological sciences : an official journal of the Society of Toxicology, 2013, Volume: 136, Issue:1

    Topics: Animals; ATP Binding Cassette Transporter, Subfamily B; ATP Binding Cassette Transporter, Subfamily

2013
Experience of low-dose aminophylline use to relieve minor adverse effects of dipyridamole in patients undergoing stress myocardial perfusion imaging.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2014, Volume: 21, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Aminophylline; Cardiotonic Agents; Comorbidity; Coronary Artery Dise

2014
Conduction abnormalities during dipyridamole stress testing.
    Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology, 2017, Volume: 24, Issue:2

    Topics: Atrioventricular Block; Bradycardia; Causality; Comorbidity; Coronary Artery Disease; Dipyridamole;

2017
Safety of intravenous thrombolysis for acute ischemic stroke in patients receiving antiplatelet therapy at stroke onset.
    Stroke, 2010, Volume: 41, Issue:2

    Topics: Acute Disease; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Cerebral Hemorrh

2010
Evaluation of the Tg.AC assay: specificity testing with three noncarcinogenic pharmaceuticals that induce selected stress gene promoters in vitro and the inhibitory effects of solvent components.
    Toxicological sciences : an official journal of the Society of Toxicology, 2003, Volume: 74, Issue:2

    Topics: Acetone; Administration, Topical; Amiloride; Animal Testing Alternatives; Animals; Carcinogenicity T

2003