dipyridamole has been researched along with Acute Coronary Syndrome in 12 studies
Dipyridamole: A phosphodiesterase inhibitor that blocks uptake and metabolism of adenosine by erythrocytes and vascular endothelial cells. Dipyridamole also potentiates the antiaggregating action of prostacyclin. (From AMA Drug Evaluations Annual, 1994, p752)
dipyridamole : A pyrimidopyrimidine that is 2,2',2'',2'''-(pyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol substituted by piperidin-1-yl groups at positions 4 and 8 respectively. A vasodilator agent, it inhibits the formation of blood clots.
Acute Coronary Syndrome: An episode of MYOCARDIAL ISCHEMIA that generally lasts longer than a transient anginal episode that ultimately may lead to MYOCARDIAL INFARCTION.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Myocardial perfusion imaging (MPI) could prove effective in the risk stratification of patients in whom acute coronary syndromes are ruled out by electrocardiography and troponin levels, thanks to its incremental sensitivity beyond that of wall motion (WM) criteria for obstructive coronary artery disease, and still maintain the excellent safety profile of dipyridamole-atropine stress echocardiography (DASE)." | 5.14 | Contrast stress echocardiography for the diagnosis of coronary artery disease in patients with chest pain but without acute coronary syndrome: incremental value of myocardial perfusion. ( Ardissino, D; De Iaco, G; Gaibazzi, N; Gherli, T; Reverberi, C; Squeri, A, 2009) |
| " In comparison with mono antiplatelet therapy, dual therapy (aspirin+dipyridamole and aspirin+clopidogrel) significantly reduced stroke recurrence, dual 58 (3." | 4.88 | Dual or mono antiplatelet therapy for patients with acute ischemic stroke or transient ischemic attack: systematic review and meta-analysis of randomized controlled trials. ( Algra, A; Bath, MW; Bath, PM; Chen, C; Dengler, R; Diener, HC; Geeganage, CM; Markus, HS; Topol, EJ, 2012) |
| "This study followed a multicenter cohort of 718 patients for 16 months after high-dose dipyridamole contrast SE for evaluation of known or suspected coronary artery disease." | 3.79 | Comparative prediction of cardiac events by wall motion, wall motion plus coronary flow reserve, or myocardial perfusion analysis: a multicenter study of contrast stress echocardiography. ( Bartolomucci, F; Gaibazzi, N; Lorenzoni, V; Marwick, TH; Molinaro, S; Reverberi, C; Rigo, F, 2013) |
| "Dipyridamole (DP) is a phosphodiesterase inhibitor that increases the intracellular levels of cyclic adenosine monophosphate (cAMP) and cyclic guanine monophosphate (cGMP) by preventing their conversion to AMP and GMP, respectively." | 2.44 | Translational therapeutics of dipyridamole. ( Kim, HH; Liao, JK, 2008) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (50.00) | 29.6817 |
| 2010's | 6 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Gaibazzi, N | 2 |
| Reverberi, C | 2 |
| Squeri, A | 1 |
| De Iaco, G | 1 |
| Ardissino, D | 1 |
| Gherli, T | 1 |
| Potter, BJ | 1 |
| Dorais, M | 1 |
| Mansour, S | 1 |
| Orlicka, K | 1 |
| Gobeil, F | 1 |
| Rinfret, S | 1 |
| Gebel, JM | 1 |
| Vestergaard, P | 1 |
| Steinberg, TH | 1 |
| Schwarz, P | 1 |
| Jørgensen, NR | 1 |
| van Giezen, JJ | 1 |
| Sidaway, J | 1 |
| Glaves, P | 1 |
| Kirk, I | 1 |
| Björkman, JA | 1 |
| Geeganage, CM | 1 |
| Diener, HC | 1 |
| Algra, A | 1 |
| Chen, C | 1 |
| Topol, EJ | 1 |
| Dengler, R | 1 |
| Markus, HS | 1 |
| Bath, MW | 1 |
| Bath, PM | 1 |
| Rigo, F | 1 |
| Lorenzoni, V | 1 |
| Molinaro, S | 1 |
| Bartolomucci, F | 1 |
| Marwick, TH | 1 |
| Ascione, L | 1 |
| Carlomagno, G | 1 |
| Sordelli, C | 1 |
| Iengo, R | 1 |
| Monda, V | 1 |
| Severino, S | 1 |
| Merenda, R | 1 |
| D'Andrea, A | 1 |
| Caso, P | 1 |
| de Azevedo, JC | 1 |
| Félix, RC | 1 |
| Corrêa, PL | 1 |
| Barbirato, GB | 1 |
| Dohmann, HF | 1 |
| da Silva, PR | 1 |
| Mesquita, ET | 1 |
| Mesquita, CT | 1 |
| Rossi, A | 1 |
| Moccetti, T | 1 |
| Faletra, F | 1 |
| Cattaneo, P | 1 |
| Rossi, M | 1 |
| Pasotti, E | 1 |
| Fantoni, C | 1 |
| Anzà, C | 1 |
| Baravelli, M | 1 |
| Kim, HH | 1 |
| Liao, JK | 1 |
| Nielsen, AA | 1 |
| Veien, KT | 1 |
| Jørgensen, LG | 1 |
| Buck, TC | 1 |
| Brandslund, I | 1 |
| Christensen, C | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Comparison of Dobutamine Stress Echocardiography and Fractional Flow Reserve in Patients With Moderate Coronary Artery Disease: Stable and Non-culprit Lesions Investigation[NCT03383718] | 200 participants (Actual) | Observational | 2014-12-01 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
3 reviews available for dipyridamole and Acute Coronary Syndrome
| Article | Year |
|---|---|
Heterogeneity of efficacy and safety of antiplatelet therapy in cardiovascular and cerebrovascular disease.
Topics: Acute Coronary Syndrome; Aspirin; Cardiovascular Diseases; Cerebrovascular Disorders; Clinical Trial | 2010 |
Dual or mono antiplatelet therapy for patients with acute ischemic stroke or transient ischemic attack: systematic review and meta-analysis of randomized controlled trials.
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Aspirin; Brain Ischemia; Clopidogrel; Datab | 2012 |
Translational therapeutics of dipyridamole.
Topics: Acute Coronary Syndrome; Animals; Cyclic AMP; Cyclic GMP; Dipyridamole; Disease Models, Animal; Endo | 2008 |
1 trial available for dipyridamole and Acute Coronary Syndrome
| Article | Year |
|---|---|
Contrast stress echocardiography for the diagnosis of coronary artery disease in patients with chest pain but without acute coronary syndrome: incremental value of myocardial perfusion.
Topics: Acute Coronary Syndrome; Aged; Chest Pain; Contrast Media; Coronary Artery Disease; Dipyridamole; Ec | 2009 |
8 other studies available for dipyridamole and Acute Coronary Syndrome
| Article | Year |
|---|---|
Effectiveness of myocardial perfusion scintigraphy to predict coronary anatomy in patients with non-ST elevation acute coronary syndrome.
Topics: Acute Coronary Syndrome; Aged; Coronary Angiography; Coronary Vessels; Dipyridamole; Electrocardiogr | 2009 |
Use of the oral platelet inhibitors dipyridamole and acetylsalicylic acid is associated with increased risk of fracture.
Topics: Acute Coronary Syndrome; Adult; Aged; Aspirin; Case-Control Studies; Clopidogrel; Dipyridamole; Drug | 2012 |
Ticagrelor inhibits adenosine uptake in vitro and enhances adenosine-mediated hyperemia responses in a canine model.
Topics: Acute Coronary Syndrome; Adenosine; Animals; Cell Line; Cell Line, Tumor; Coronary Circulation; Dipy | 2012 |
Comparative prediction of cardiac events by wall motion, wall motion plus coronary flow reserve, or myocardial perfusion analysis: a multicenter study of contrast stress echocardiography.
Topics: Acute Coronary Syndrome; Aged; Biomechanical Phenomena; Chi-Square Distribution; Contrast Media; Cor | 2013 |
Dipyridamole coronary flow reserve stratifies prognosis in acute coronary syndrome patients without left anterior descending disease.
Topics: Acute Coronary Syndrome; Coronary Angiography; Dipyridamole; Disease Progression; Echocardiography, | 2013 |
Medium term prognostic value of stress myocardial perfusion scintigraphy in a chest pain unit.
Topics: Acute Coronary Syndrome; Aged; Angina Pectoris; Cohort Studies; Dipyridamole; Disease-Free Survival; | 2007 |
Dipyridamole stress echocardiography stratifies outcomes of asymptomatic patients with recent myocardial revascularization.
Topics: Acute Coronary Syndrome; Aged; Angioplasty, Balloon, Coronary; Coronary Angiography; Coronary Artery | 2008 |
[Antiplatelet treatment after acute and chronic ischemic heart and brain events is insufficient according to recommendations].
Topics: Acute Coronary Syndrome; Adult; Aged; Aged, 80 and over; Angina Pectoris; Angina, Unstable; Aspirin; | 2008 |