Page last updated: 2024-10-26

dipropizine and Cough

dipropizine has been researched along with Cough in 26 studies

Cough: A sudden, audible expulsion of air from the lungs through a partially closed glottis, preceded by inhalation. It is a protective response that serves to clear the trachea, bronchi, and/or lungs of irritants and secretions, or to prevent aspiration of foreign materials into the lungs.

Research Excerpts

ExcerptRelevanceReference
"Codeine is an effective and generally well-tolerated antitussive for chronic cough."9.51Effectiveness and Safety of Codeine and Levodropropizine in Patients With Chronic Cough. ( Kang, SY; Lee, BJ; Lee, SM; Lee, SP, 2022)
" Tolerability was evaluated by laboratory results, vital signs and any adverse event occurring during the clinical trial, including presence or absence of somnolence."6.69Efficacy and safety of levodropropizine and dihydrocodeine on nonproductive cough in primary and metastatic lung cancer. ( Barni, S; Daffonchio, L; Luporini, G; Marchi, E, 1998)
"Levocloperastine is an effective antitussive agent for the treatment of cough in patients of all ages."6.42Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents. ( Aliprandi, P; Bernorio, S; Carrara, M; Castelli, C; Dell'Abate, E, 2004)
"Codeine is an effective and generally well-tolerated antitussive for chronic cough."5.51Effectiveness and Safety of Codeine and Levodropropizine in Patients With Chronic Cough. ( Kang, SY; Lee, BJ; Lee, SM; Lee, SP, 2022)
"At variance with dihydrocodeine, levodropropizine and placebo did not affect respiratory responses to hypercapnia (P < ."5.24A Randomized Clinical Trial Comparing the Effects of Antitussive Agents on Respiratory Center Output in Patients With Chronic Cough. ( Fontana, G; Lanata, L; Lavorini, F; Mannini, C; Saibene, F; Zanasi, A, 2017)
"The effects of four antitussives, including codeine phosphate (CP), moguisteine, levodropropizine (LVDP) and naringin, on airway neurogenic inflammation and enhanced cough were investigated in guinea pig model of chronic cough."3.79Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure. ( Li, PB; Luo, YL; Nie, YC; Su, WW; Wang, S; Zhang, CC; Zhang, KJ; Zheng, YF, 2013)
"In this study we have evaluated the cough reflex inhibiting potential and modulation of ASM reactivity in vitro, by K+ATP opener-pinacidil in guinea pig and cats."3.75The influence of animal species on the relationship between ATP-sensitive potassium ion channels and defense reflexes of the airways. ( Franova, S; Sutovska, M; Sutovsky, J, 2009)
"The aim of the study was to investigate the effect of diltiazem administration on the sensitivity of the mechanically induced cough reflex in experimental conditions."3.72Antitussive effect of diltiazem in experimental conditions. ( Franova, S; Nosalova, G, 2004)
" Intravenously, it was 1/10 to 1/20 as active as codeine and comparable to dropropizine, from which it is derived, on mechanically and electrically induced coughing in rabbits and guinea-pigs."3.67Antitussive properties of levodropropizine. ( Bestetti, A; Borsa, M; Giuliani, P; Malandrino, S; Melillo, G; Tonon, GC, 1988)
" Due to the widespread use of antitussives in the clinic it is necessary to develop efficient analytical methodologies for quality control and also for pharmacokinetic, bioavailability and bioequivalence studies."2.72Characteristics, Properties and Analytical Methods for Determination of Dropropizine and Levodropropizine: A Review. ( Machado, AKMDS; Nemitz, MC; Sangoi, MDS; Todeschini, V, 2021)
"An acute cough is usually consequent to upper respiratory tract infections and is self-resolving within a few weeks."2.72Acute cough in children and adolescents: A systematic review and a practical algorithm by the Italian Society of Pediatric Allergy and Immunology. ( Brambilla, I; Caffarelli, C; Calvani, M; Cardinale, F; Chiappini, E; Ciprandi, G; Cravidi, C; Del Giudice, MM; Duse, M; Licari, A; Manti, S; Marseglia, GL; Martelli, A; Minasi, D; Pajno, G; Peroni, DG; Tosca, MA, 2021)
" Tolerability was evaluated by laboratory results, vital signs and any adverse event occurring during the clinical trial, including presence or absence of somnolence."2.69Efficacy and safety of levodropropizine and dihydrocodeine on nonproductive cough in primary and metastatic lung cancer. ( Barni, S; Daffonchio, L; Luporini, G; Marchi, E, 1998)
"Cough is a protective reflex that serves to clear the airways of excessive secretions and foreign matter and which sometimes becomes excessive, and troublesome to patients."2.61Antitussive therapy: A role for levodropropizine. ( Birring, S; de Blasio, F; Dicpinigaitis, PV; Fontana, G; Lanata, L; Page, C; Saibene, F; Zanasi, A, 2019)
"Cough associated with cancer or nonmalignant chronic disease is common and distressing."2.47Levodropropizine in the management of cough associated with cancer or nonmalignant chronic disease--a systematic review. ( Bausewein, C; Rémi, C; Schildmann, EK, 2011)
"Levocloperastine is an effective antitussive agent for the treatment of cough in patients of all ages."2.42Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents. ( Aliprandi, P; Bernorio, S; Carrara, M; Castelli, C; Dell'Abate, E, 2004)
" Levodropropizine, at the dosage of 60 mg t."1.27Antitussive activity and respiratory system effects of levodropropizine in man. ( Allegra, L; Bossi, R; Braga, PC; Centanni, S; Legnani, D; Moavero, NE, 1988)

Research

Studies (26)

TimeframeStudies, this research(%)All Research%
pre-19904 (15.38)18.7374
1990's9 (34.62)18.2507
2000's3 (11.54)29.6817
2010's6 (23.08)24.3611
2020's4 (15.38)2.80

Authors

AuthorsStudies
Lee, SP1
Lee, SM1
Lee, BJ1
Kang, SY1
Machado, AKMDS1
Nemitz, MC1
Todeschini, V1
Sangoi, MDS1
Marseglia, GL2
Manti, S1
Chiappini, E1
Brambilla, I1
Caffarelli, C1
Calvani, M1
Cardinale, F1
Cravidi, C1
Duse, M1
Martelli, A1
Minasi, D1
Del Giudice, MM1
Pajno, G1
Peroni, DG1
Tosca, MA2
Licari, A2
Ciprandi, G2
Birring, S1
de Blasio, F2
Dicpinigaitis, PV2
Fontana, G2
Lanata, L3
Page, C2
Saibene, F2
Zanasi, A3
Luo, YL1
Li, PB1
Zhang, CC1
Zheng, YF1
Wang, S1
Nie, YC1
Zhang, KJ1
Su, WW1
Clay, E1
Patacchini, R1
Trevisani, M1
Preti, D1
Branà, MP1
Spina, D1
Mannini, C1
Lavorini, F1
Sutovska, M1
Franova, S2
Sutovsky, J1
Schildmann, EK1
Rémi, C1
Bausewein, C1
De Danieli, G1
Nosalova, G1
Aliprandi, P1
Castelli, C1
Bernorio, S1
Dell'Abate, E1
Carrara, M1
Nosál'ová, G2
Strapková, A2
Korpás, J1
Munt, PL1
Clavenna, G2
Algate, DR1
Leach, RM1
Catena, E2
Daffonchio, L2
Luporini, G1
Barni, S1
Marchi, E1
Fumagalli, G1
Cordaro, CI1
Vanasia, M1
Balzarotti, C1
Camusso, L1
Caiazzo, G1
Maghini, L1
Mazzocchi, M1
Zennaro, M1
Bariffi, F1
Tranfa, C1
Vatrella, A1
Ponticiello, A1
Lavezzo, A1
Melillo, G2
Omini, C1
Guarino, C1
Cautiero, V1
Cordaro, C1
Jahodar, L1
Bejor, M1
Arrigo, A1
Allegra, L2
Bossi, R2
Malandrino, S1
Bestetti, A1
Borsa, M1
Giuliani, P1
Tonon, GC1
Braga, PC1
Centanni, S1
Legnani, D1
Moavero, NE1

Reviews

6 reviews available for dipropizine and Cough

ArticleYear
Characteristics, Properties and Analytical Methods for Determination of Dropropizine and Levodropropizine: A Review.
    Critical reviews in analytical chemistry, 2021, Volume: 51, Issue:2

    Topics: Antitussive Agents; Chromatography, High Pressure Liquid; Cough; Gas Chromatography-Mass Spectrometr

2021
Acute cough in children and adolescents: A systematic review and a practical algorithm by the Italian Society of Pediatric Allergy and Immunology.
    Allergologia et immunopathologia, 2021, Volume: 49, Issue:2

    Topics: Acute Disease; Adolescent; Allergy and Immunology; Antitussive Agents; Apitherapy; Child; Child, Pre

2021
Antitussive therapy: A role for levodropropizine.
    Pulmonary pharmacology & therapeutics, 2019, Volume: 56

    Topics: Animals; Antitussive Agents; Cough; Drug Development; Humans; Propylene Glycols

2019
Levodropropizine in the management of cough associated with cancer or nonmalignant chronic disease--a systematic review.
    Journal of pain & palliative care pharmacotherapy, 2011, Volume: 25, Issue:3

    Topics: Antitussive Agents; Chronic Disease; Cough; Heart Failure; Humans; Lung Diseases; Neoplasms; Propyle

2011
Efficacy of levodropropizine in pediatric cough.
    Pulmonary pharmacology & therapeutics, 2012, Volume: 25, Issue:5

    Topics: Antitussive Agents; Cough; Humans; Propylene Glycols; Quality of Life

2012
Levocloperastine in the treatment of chronic nonproductive cough: comparative efficacy versus standard antitussive agents.
    Drugs under experimental and clinical research, 2004, Volume: 30, Issue:4

    Topics: Adolescent; Adult; Aged; Antitussive Agents; Bronchitis; Chronic Disease; Clinical Trials as Topic;

2004

Trials

9 trials available for dipropizine and Cough

ArticleYear
Effectiveness and Safety of Codeine and Levodropropizine in Patients With Chronic Cough.
    Journal of Korean medical science, 2022, Sep-19, Volume: 37, Issue:36

    Topics: Antitussive Agents; Chronic Disease; Codeine; Cough; Humans; Propylene Glycols

2022
A Randomized Clinical Trial Comparing the Effects of Antitussive Agents on Respiratory Center Output in Patients With Chronic Cough.
    Chest, 2017, Volume: 151, Issue:6

    Topics: Adult; Aged; Antitussive Agents; Chronic Disease; Codeine; Cough; Cross-Over Studies; Female; Humans

2017
Efficacy and tolerability of levodropropizine in adult patients with non-productive cough. Comparison with dextromethorphan.
    Pulmonary pharmacology & therapeutics, 1997, Volume: 10, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitussive Agents; Cough; Dextromethorphan; Double-Blin

1997
Efficacy and safety of levodropropizine and dihydrocodeine on nonproductive cough in primary and metastatic lung cancer.
    The European respiratory journal, 1998, Volume: 12, Issue:1

    Topics: Administration, Oral; Adult; Aged; Analgesics, Opioid; Antitussive Agents; Codeine; Cough; Dose-Resp

1998
A comparative study of the antitussive activity of levodropropizine and dropropizine in the citric acid-induced cough model in normal subjects.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:7

    Topics: Adult; Antitussive Agents; Citrates; Citric Acid; Cough; Double-Blind Method; Female; Humans; Lung;

1992
Protective effect of levodropropizine against cough induced by inhalation of nebulized distilled water in patients with obstructive lung disease.
    Drugs under experimental and clinical research, 1992, Volume: 18, Issue:3

    Topics: Adolescent; Adult; Antitussive Agents; Asthma; Bronchitis; Chronic Disease; Cough; Double-Blind Meth

1992
Levodropropizine in the premedication to fibrebronchoscopy.
    Drugs under experimental and clinical research, 1991, Volume: 17, Issue:4

    Topics: Adult; Aged; Antitussive Agents; Bronchoscopy; Cough; Female; Humans; Lung Diseases; Male; Middle Ag

1991
[Evaluation of the safety of antitussive agents during respiratory rehabilitation. A clinical study of L-dropropizine].
    La Clinica terapeutica, 1990, Jun-30, Volume: 133, Issue:6

    Topics: Adult; Antitussive Agents; Cough; Female; Humans; Lung Diseases, Obstructive; Male; Middle Aged; Pro

1990
Clinical trials with the new antitussive levodropropizine in adult bronchitic patients.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:8

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Antitussive Agents; Benzophenones; Bronchitis; Clinical

1988

Other Studies

11 other studies available for dipropizine and Cough

ArticleYear
Levodropropizine in children: over thirty years of clinical experience.
    Journal of biological regulators and homeostatic agents, 2021, Aug-27, Volume: 35, Issue:4

    Topics: Child; Cough; Humans; Propylene Glycols

2021
Effects of four antitussives on airway neurogenic inflammation in a guinea pig model of chronic cough induced by cigarette smoke exposure.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 2013, Volume: 62, Issue:12

    Topics: Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Female; Flavanones; Guinea Pigs; Lung; Male;

2013
Ozone-Induced Hypertussive Responses in Rabbits and Guinea Pigs.
    The Journal of pharmacology and experimental therapeutics, 2016, Volume: 357, Issue:1

    Topics: Aminopyridines; Animals; Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Benzamides; Br

2016
The influence of animal species on the relationship between ATP-sensitive potassium ion channels and defense reflexes of the airways.
    Bratislavske lekarske listy, 2009, Volume: 110, Issue:5

    Topics: Animals; Antitussive Agents; Cats; Citric Acid; Cough; Female; Glyburide; Guinea Pigs; KATP Channels

2009
Antitussive effect of diltiazem in experimental conditions.
    Bratislavske lekarske listy, 2004, Volume: 105, Issue:5-6

    Topics: Animals; Antitussive Agents; Cats; Codeine; Cough; Diltiazem; Larynx; Physical Stimulation; Propylen

2004
[A new antitussive agent--Ditustat Spofa].
    Bratislavske lekarske listy, 1982, Volume: 78, Issue:3

    Topics: Animals; Antitussive Agents; Cats; Cough; Propylene Glycols

1982
Antitussive effects of levodropropizine in the dog.
    Arzneimittel-Forschung, 1994, Volume: 44, Issue:2

    Topics: Animals; Antitussive Agents; Codeine; Cough; Dogs; Dose-Response Relationship, Drug; Electric Stimul

1994
Peripheral site of action of levodropropizine in experimentally-induced cough: role of sensory neuropeptides.
    Pulmonary pharmacology, 1992, Volume: 5, Issue:2

    Topics: Animals; Antitussive Agents; Capsaicin; Codeine; Cough; Electric Stimulation; Guinea Pigs; Injection

1992
Antitussive effect of arbutin.
    Die Pharmazie, 1991, Volume: 46, Issue:8

    Topics: Animals; Antitussive Agents; Arbutin; Cats; Cough; Female; Male; Propylene Glycols

1991
Antitussive properties of levodropropizine.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:8

    Topics: Administration, Oral; Animals; Antitussive Agents; Codeine; Cough; Dose-Response Relationship, Drug;

1988
Antitussive activity and respiratory system effects of levodropropizine in man.
    Arzneimittel-Forschung, 1988, Volume: 38, Issue:8

    Topics: Adult; Antitussive Agents; Bronchitis; Cilia; Cough; Epithelium; Female; Humans; Male; Propylene Gly

1988