Page last updated: 2024-10-26

dipivefrin and Intraocular Pressure

dipivefrin has been researched along with Intraocular Pressure in 60 studies

dipivefrin: used in treatment of both primary & open angle glaucoma; RN given refers to (+-)-isomer
dipivefrin : The dipivalate ester of (+-)-epinephrine (racepinephrine). A pro-drug of epinephrine, the hydrochloride is used topically as eye drops to reduce intra-ocular pressure in the treatment of open-angle glaucoma or ocular hypertension.

Intraocular Pressure: The pressure of the fluids in the eye.

Research Excerpts

ExcerptRelevanceReference
"To investigate the effect on intraocular pressure (IOP) and aqueous flare of topical applications of latanoprost and dipivefrin alone or combined."9.08Effects of latanoprost and dipivefrin, alone or combined, on intraocular pressure and on blood-aqueous barrier permeability. ( Alm, A; Mäepea, O; Widengård, I, 1998)
"In this double-blind prospective trial the efficacy of lowering the intraocular pressure of l-moprolol given alone and in combination with dipivefrin was tested."9.07The efficacy of the combination of l-moprolol and dipivefrin in reducing the intraocular pressure in primary open-angle glaucoma or in ocular hypertension. ( Barbieri, P; Bujtar, E; Orzalesi, N; Rossetti, L; Velati, P, 1994)
"The authors compared the additive intraocular pressure (IOP)-lowering effects of two different topical medications, apraclonidine hydrochloride and dipivefrin hydrochloride, when used in conjunction with timolol maleate."9.06Adjunctive glaucoma therapy. A comparison of apraclonidine to dipivefrin when added to timolol maleate. ( Morrison, JC; Robin, AL, 1989)
" Latanoprost produces an additional reduction of intraocular pressure (IOP) when used in combination with timolol, pilocarpine, acetazolamide and dipivefrin."8.79The additive intraocular pressure-lowering effect of latanoprost in combined therapy with other ocular hypotensive agents. ( Alm, A; Greve, E; Hoyng, PF; Rulo, A; Watson, P, 1997)
"The pH and dose dependencies of topically applied dipivefrine hydrochloride (DPE) on intraocular pressure (IOP) reduction and mydriasis were compared with those of epinephrine bitartrate (EPI) in normal rabbits."7.67pH dependency of effect of topically applied dipivefrine hydrochloride on intraocular pressure and pupil size in rabbits: comparative studies with epinephrine. ( Iso, T; Sasano, M; Yamauchi, H, 1988)
"Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure."7.67[Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure]. ( Dausch, D; Ober, M; Scharrer, A, 1987)
"The author considers that the combined use of pilocarpine and Dipivefrin (Thiloadren) represents an additional effective method of regulating pressure as physiologically as possible in glaucomatous eyes with trophic disorders, thus further reducing the need for surgery."7.66[Treatment of glaucoma with a pilocarpine-dipivefrin combination (author's transl)]. ( Niedermeier, S, 1981)
"In a randomized clinical trial, 100 consecutive subjects with ocular hypertension or high-tension primary open-angle glaucoma in at least one eye were randomly assigned to either group A, which was administered timolol 0."5.08Serial administration of adrenergic antagonist and agonist ("pulsatile therapy") reduces the incidence of long-term drift to timolol in humans. ( Gandolfi, SA; Vecchi, M, 1996)
"To investigate the effect on intraocular pressure (IOP) and aqueous flare of topical applications of latanoprost and dipivefrin alone or combined."5.08Effects of latanoprost and dipivefrin, alone or combined, on intraocular pressure and on blood-aqueous barrier permeability. ( Alm, A; Mäepea, O; Widengård, I, 1998)
"In this double-blind prospective trial the efficacy of lowering the intraocular pressure of l-moprolol given alone and in combination with dipivefrin was tested."5.07The efficacy of the combination of l-moprolol and dipivefrin in reducing the intraocular pressure in primary open-angle glaucoma or in ocular hypertension. ( Barbieri, P; Bujtar, E; Orzalesi, N; Rossetti, L; Velati, P, 1994)
"The authors compared the additive intraocular pressure (IOP)-lowering effects of two different topical medications, apraclonidine hydrochloride and dipivefrin hydrochloride, when used in conjunction with timolol maleate."5.06Adjunctive glaucoma therapy. A comparison of apraclonidine to dipivefrin when added to timolol maleate. ( Morrison, JC; Robin, AL, 1989)
" Latanoprost produces an additional reduction of intraocular pressure (IOP) when used in combination with timolol, pilocarpine, acetazolamide and dipivefrin."4.79The additive intraocular pressure-lowering effect of latanoprost in combined therapy with other ocular hypotensive agents. ( Alm, A; Greve, E; Hoyng, PF; Rulo, A; Watson, P, 1997)
"Thirteen patients with normal-tension glaucoma with a cystic filtering bleb who had undergone unilateral trabeculectomy with mitomycin C only once at least 1 year previously were subjected to the study."3.69Epithelial barrier function of the filtering bleb conjunctiva and the cornea after trabeculectomy with mitomycin C. ( Haque, MS; Kinoshita, S; Kitazawa, Y; Komuro, A; Mochizuki, K; Taniguchi, T; Yamamoto, T; Yokoi, N, 1996)
" Nine patients with ocular hypertension receiving treatment with timolol were entered into the study."3.68Long-term drift and timolol therapy: possible role for pulsed therapy. ( Batterbury, M; Harding, SP; Wong, D, 1992)
"The intraocular pressure (IOP) and pupillary effects of dipivalyl esters of epinephrine and alpha-methylepinephrine were compared after topical application in conscious rabbits."3.68Ocular effects of dipivalyl esters of epinephrine and alpha-methylepinephrine. ( Gherezghiher, T; Koss, MC, 1990)
"1% dipivefrin hydrochloride was instilled in a randomized, double-blind fashion in eyes treated with timolol maleate no change in heart rate, intraocular pressure or rate of aqueous outflow was noted."3.67Cardiovascular effects of epinephrine and dipivefrin in patients using timolol: a single-dose study. ( Blondeau, P; Côté, M, 1984)
"The pH and dose dependencies of topically applied dipivefrine hydrochloride (DPE) on intraocular pressure (IOP) reduction and mydriasis were compared with those of epinephrine bitartrate (EPI) in normal rabbits."3.67pH dependency of effect of topically applied dipivefrine hydrochloride on intraocular pressure and pupil size in rabbits: comparative studies with epinephrine. ( Iso, T; Sasano, M; Yamauchi, H, 1988)
"Thirty patients with ocular hypertension or open-angle glaucoma were tested to see if, and to what extent, guanethidine/dipivefrin and pilocarpine produced a supplementary reduction in intraocular pressure."3.67[Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure]. ( Dausch, D; Ober, M; Scharrer, A, 1987)
"A survey of the literature concerning the interaction of timolol and epinephrine in lowering intraocular pressure, and a study comparing the efficacy of timolol and dipivefrin (a prodrug of epinephrine) to that of timolol and pilocarpine are presented."3.66Combined timolol and epinephrine therapy for open angle glaucoma. ( Hurvitz, L; Knupp, JA; Mandell, AI; Shields, MB; Spaeth, GL, 1983)
" Relative to its less lipid soluble parent compound, dipivefrin has been shown in clinical trials to control intraocular pressure effectively at concentrations 10-20 times less than epinephrine with a resultant decreased incidence of ocular and systemic side effects."3.66An advance in ophthalmic pharmacology. The use of the epinephrine pro-drug dipivalyl epinephrine in the treatment of glaucoma. ( Garzia, R, 1982)
"The author considers that the combined use of pilocarpine and Dipivefrin (Thiloadren) represents an additional effective method of regulating pressure as physiologically as possible in glaucomatous eyes with trophic disorders, thus further reducing the need for surgery."3.66[Treatment of glaucoma with a pilocarpine-dipivefrin combination (author's transl)]. ( Niedermeier, S, 1981)
"05% dipivefrin every 12 hours might be an adequate dosage for maximal effect."2.67Nasolacrimal occlusion improves the therapeutic index of antiglaucoma medications. ( Sharir, M; Zimmerman, TJ, 1994)
"The prevalence of open angle glaucoma is disproportionately high in the African American population."2.67Levobunolol compared to dipivefrin in African American patients with open angle glaucoma. ( Drake, MV; Goodwin, L; Harris, D; Wilson, MR, 1993)
"1% dipivefrin are at the top of the dose-response curve."2.67Therapeutic index of epinephrine and dipivefrin with nasolacrimal occlusion. ( Fuqua, M; Nardin, GF; Sharir, M; Zimmerman, TJ, 1992)
"Dipivefrin is a safe, effective, and well-tolerated alternative to epinephrine in the treatment of elevated IOP."2.65Dipivefrin: current concepts. ( Becker, B; Goldberg, I; Kass, MA; Kolker, AE, 1980)
"The mean pretreatment intraocular pressure (IOP), 40."1.29Transscleral neodymium:YAG laser cyclophotocoagulation for end-stage glaucoma, refractory glaucoma, and painful blind eyes. ( al-Ghamdi, S; al-Jadaan, I; al-Obeidan, S; Tomey, KF, 1993)
"D,L-dipivefrin hydrochloride was administered bilaterally to rabbit eyes five or 150 minutes after unilateral application of a cholinesterase inhibitor."1.27Enzymatic and nonenzymatic hydrolysis of D,L-dipivefrin. ( Barker, LA; Cohen, G; Lewis, DE; Mindel, JS, 1984)
"When dipivefrin was administered with echothiophate plus phentolamine, there was an immediate hypotensive effect."1.26The effect of echothiophate on the biphasic response of rabbit ocular pressure to dipivefrin. ( Goldfarb, J; Kharlamb, AB; Koenigsberg, AM; Mindel, JS; Orellana, J, 1982)
"Dipivefrin was administered singly and in combination with echothiophate to 24 adult rabbits."1.26Dipivefrin and echothiophate: contraindications to combined use. ( Abramovsky, I; Mindel, JS, 1979)
"1%) developed adverse external ocular side effects severe enough to require that the drug be discontinued."1.26External ocular toxicity of dipivalyl epinephrine. ( Leibowitz, HM; Theodore, J, 1979)

Research

Studies (60)

TimeframeStudies, this research(%)All Research%
pre-199030 (50.00)18.7374
1990's26 (43.33)18.2507
2000's3 (5.00)29.6817
2010's1 (1.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Nakamura-Shibasaki, M1
Latief, MA1
Ko, JA1
Funaishi, K1
Kiuchi, Y1
Lin, JC1
Samuel, F1
Katz, LJ1
Spaeth, GL2
Hoop, J1
Cantor, LB1
Călugăru, M1
Călugăru, D1
Mindel, JS4
Koenigsberg, AM1
Kharlamb, AB1
Goldfarb, J1
Orellana, J2
West, RH3
Cebon, L2
Gillies, WE4
Knupp, JA1
Shields, MB1
Mandell, AI1
Hurvitz, L1
Cohen, G1
Barker, LA1
Lewis, DE1
Blondeau, P1
Côté, M1
Goldberg, I1
Kolker, AE1
Kass, MA1
Becker, B1
Frumar, KD3
McGuinness, R3
Kerr, CR1
Hass, I1
Drance, SM1
Walters, MB1
Schulzer, M1
Garzia, R1
Niedermeier, S1
Yablonski, ME1
Tavitian, HO1
Podos, SM2
Keates, EU1
Stone, RA1
Rossetti, L1
Barbieri, P1
Velati, P1
Bujtar, E1
Orzalesi, N1
Alimgil, ML1
Erda, S1
Benian, O1
Shao, H1
Sun, XY1
Bai, FG1
Sharir, M2
Zimmerman, TJ3
Drake, MV1
Wilson, MR1
Harris, D1
Goodwin, L1
Michelson, G1
Groh, MJ1
al-Ghamdi, S1
al-Obeidan, S1
Tomey, KF1
al-Jadaan, I1
Albracht, DC1
LeBlanc, RP1
Cruz, AM1
Lamping, KA1
Siegel, LI1
Stern, KL1
Kelley, EP1
Stoecker, JF1
Gandolfi, SA2
Vecchi, M1
Taniguchi, T1
Yamamoto, T1
Mochizuki, K1
Haque, MS1
Kitazawa, Y1
Yokoi, N1
Komuro, A1
Kinoshita, S1
Werner, E1
Koseki, N1
Araie, M1
Shirato, S1
Yamagami, J1
Hoyng, PF1
Rulo, A1
Greve, E1
Watson, P1
Alm, A2
Werner, EB1
Widengård, I1
Mäepea, O1
Brooks, AM2
Lannek, EB1
Miller, PE1
Kohn, AN1
Moss, AP1
Hargett, NA1
Ritch, R1
Smith, H1
Abramovsky, I1
Theodore, J1
Leibowitz, HM1
Gwin, RM1
Gelatt, KN1
Gum, GG1
Peiffer, RL1
Batterbury, M1
Harding, SP1
Wong, D1
Ophir, A1
Ticho, U1
Nardin, GF1
Fuqua, M1
Brown, RH1
Shin, DH2
Tsai, CS1
Parrow, KA2
Kim, C1
Wan, JY1
Shi, DX2
Chang, JS1
Lee, DA1
Petursson, G1
Spaeth, G1
Hoskins, HD1
Mills, R1
Brown, R1
Kass, M1
Lue, J1
Gherezghiher, T1
Koss, MC1
Robin, AL4
Hong, YJ1
McCarty, B1
Morrison, JC2
Dandona, L1
Quigley, HA1
Leopold, IH1
Duzman, E1
Soll, DB1
Saxon, AM1
Yamauchi, H1
Sasano, M1
Iso, T1
Allen, RC1
Long, D1
Novack, GD1
Lue, JC1
Kaplan, G1
Ober, M2
Scharrer, A2
Dausch, D1

Clinical Trials (3)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
[NCT00000144]Phase 30 participants Interventional1984-01-31Completed
Following Patients After Selective and Pascal Laser Trabeculoplasty for Treatment of Chronic Open-Angle Glaucoma[NCT02679482]36 participants (Anticipated)Observational2014-09-30Recruiting
External Micropulse Diode Laser Transscleral Trabeculoplasty(EMDLT) For Severe Open Angle Glaucoma[NCT00443664]Early Phase 130 participants (Anticipated)Interventional2006-06-30Recruiting
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

4 reviews available for dipivefrin and Intraocular Pressure

ArticleYear
[Latanoprost topical ophthalmic combinations].
    Oftalmologia (Bucharest, Romania : 1990), 2004, Volume: 48, Issue:4

    Topics: Acetazolamide; Administration, Topical; Antihypertensive Agents; Brimonidine Tartrate; Dinoprost; Dr

2004
The additive intraocular pressure-lowering effect of latanoprost in combined therapy with other ocular hypotensive agents.
    Survey of ophthalmology, 1997, Volume: 41 Suppl 2

    Topics: Acetazolamide; Adrenergic Agonists; Adrenergic beta-Antagonists; Animals; Carbonic Anhydrase Inhibit

1997
Combination therapy.
    The CLAO journal : official publication of the Contact Lens Association of Ophthalmologists, Inc, 1991, Volume: 17, Issue:2

    Topics: Adrenergic beta-Antagonists; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular P

1991
Observations on the pharmacology of glaucoma.
    Annual review of pharmacology and toxicology, 1986, Volume: 26

    Topics: Adenylyl Cyclase Inhibitors; Adrenal Cortex Hormones; Adrenergic alpha-Agonists; Adrenergic beta-Ago

1986

Trials

24 trials available for dipivefrin and Intraocular Pressure

ArticleYear
The effect of topical glaucoma medications evaluated by perimetry.
    The British journal of ophthalmology, 2003, Volume: 87, Issue:6

    Topics: Administration, Topical; Antihypertensive Agents; Betaxolol; Clonidine; Epinephrine; Glaucoma; Human

2003
Dipivefrin: current concepts.
    Australian journal of ophthalmology, 1980, Volume: 8, Issue:2

    Topics: Absorption; Biotransformation; Clinical Trials as Topic; Cornea; Epinephrine; Glaucoma; Humans; Hydr

1980
A study of the intraocular pressure lowering effect of timolol and dipivalyl epinephrine.
    Transactions of the Ophthalmological Society of New Zealand, 1981, Volume: 33

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans; I

1981
Cardiovascular effects of epinephrine and dipivalyl epinephrine applied topically to the eye in patients with glaucoma.
    The British journal of ophthalmology, 1982, Volume: 66, Issue:2

    Topics: Aged; Blood Pressure; Cardiovascular System; Clinical Trials as Topic; Double-Blind Method; Epinephr

1982
A study of the intraocular pressure lowering effect of timolol and dipivalyl epinephrine.
    Australian journal of ophthalmology, 1982, Volume: 10, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans; I

1982
Dipivefrin and echothiophate. Efficacy of combined use in human beings.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1981, Volume: 99, Issue:9

    Topics: Drug Therapy, Combination; Echothiophate Iodide; Epinephrine; Fluorometry; Glaucoma; Humans; Intraoc

1981
The efficacy of the combination of l-moprolol and dipivefrin in reducing the intraocular pressure in primary open-angle glaucoma or in ocular hypertension.
    Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie, 1994, Volume: 232, Issue:11

    Topics: Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and over; Double-Blind Method; Drug Therapy, Comb

1994
[The additive effect of dipivefrin in patients with wide angle glaucoma treated with long-term beta-blocker therapy in comparison with clonidine].
    Klinische Monatsblatter fur Augenheilkunde, 1994, Volume: 205, Issue:2

    Topics: Clonidine; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Open-Angle; Hum

1994
Nasolacrimal occlusion improves the therapeutic index of antiglaucoma medications.
    Journal of the Association for Academic Minority Physicians : the official publication of the Association for Academic Minority Physicians, 1994, Volume: 5, Issue:2

    Topics: Aged; Carbachol; Dose-Response Relationship, Drug; Double-Blind Method; Drug Therapy, Combination; E

1994
Levobunolol compared to dipivefrin in African American patients with open angle glaucoma.
    Journal of ocular pharmacology, 1993,Summer, Volume: 9, Issue:2

    Topics: Adult; Aged; Black People; Double-Blind Method; Epinephrine; Female; Glaucoma, Open-Angle; Humans; I

1993
Dipivefrin reduces blood flow in the ciliary body in humans.
    Ophthalmology, 1994, Volume: 101, Issue:4

    Topics: Administration, Topical; Adult; Blood Flow Velocity; Ciliary Body; Double-Blind Method; Electrocardi

1994
A double-masked comparison of betaxolol and dipivefrin for the treatment of increased intraocular pressure.
    American journal of ophthalmology, 1993, Sep-15, Volume: 116, Issue:3

    Topics: Aged; Betaxolol; Double-Blind Method; Epinephrine; Female; Glaucoma, Open-Angle; Heart Rate; Humans;

1993
Serial administration of adrenergic antagonist and agonist ("pulsatile therapy") reduces the incidence of long-term drift to timolol in humans.
    Investigative ophthalmology & visual science, 1996, Volume: 37, Issue:4

    Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Drug Administration Schedule; Drug Tolerance; Epin

1996
[Effect of non-surgical ocular hypotensive therapy in normal-tension glaucoma].
    Nippon Ganka Gakkai zasshi, 1997, Volume: 101, Issue:2

    Topics: Carteolol; Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Middle Ag

1997
Effects of latanoprost and dipivefrin, alone or combined, on intraocular pressure and on blood-aqueous barrier permeability.
    The British journal of ophthalmology, 1998, Volume: 82, Issue:4

    Topics: Adrenergic Agonists; Aged; Blood-Aqueous Barrier; Conjunctival Diseases; Drug Administration Schedul

1998
Clinical comparison of dipivalyl epinephrine and epinephrine in the treatment of glaucoma.
    American journal of ophthalmology, 1979, Volume: 87, Issue:2

    Topics: Adult; Aged; Clinical Trials as Topic; Double-Blind Method; Epinephrine; Female; Glaucoma; Humans; I

1979
Therapeutic index of epinephrine and dipivefrin with nasolacrimal occlusion.
    American journal of ophthalmology, 1992, Jul-15, Volume: 114, Issue:1

    Topics: Absorption; Cornea; Dose-Response Relationship, Drug; Double-Blind Method; Epinephrine; Glaucoma, Op

1992
The effect of a glaucoma medication reminder cap on patient compliance and intraocular pressure.
    Journal of ocular pharmacology, 1991,Summer, Volume: 7, Issue:2

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Drug Labeling; Epinephrine; Female; Glaucoma; Humans; In

1991
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
The Glaucoma Laser Trial (GLT). 2. Results of argon laser trabeculoplasty versus topical medicines. The Glaucoma Laser Trial Research Group.
    Ophthalmology, 1990, Volume: 97, Issue:11

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle

1990
Restoring sensitivity to timolol after long-term drift in primary open-angle glaucoma.
    Investigative ophthalmology & visual science, 1990, Volume: 31, Issue:2

    Topics: Aged; Drug Administration Schedule; Drug Tolerance; Epinephrine; Follow-Up Studies; Glaucoma, Open-A

1990
Is it worthwhile to add dipivefrin HCl 0.1% to topical beta 1-, beta 2-blocker therapy?
    Ophthalmology, 1989, Volume: 96, Issue:9

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Adult; Aged; Drug Therapy, Combination; Epinep

1989
Adjunctive glaucoma therapy. A comparison of apraclonidine to dipivefrin when added to timolol maleate.
    Ophthalmology, 1989, Volume: 96, Issue:1

    Topics: Adult; Aged; Clinical Trials as Topic; Clonidine; Drug Therapy, Combination; Epinephrine; Eye Diseas

1989
"Outlier" intraocular pressure readings: valid or invalid for statistical analysis?
    Ophthalmic surgery, 1989, Volume: 20, Issue:10

    Topics: Analysis of Variance; Clinical Trials as Topic; Clonidine; Data Interpretation, Statistical; Double-

1989
A combination of levobunolol and dipivefrin for the treatment of glaucoma.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1988, Volume: 106, Issue:7

    Topics: Drug Combinations; Epinephrine; Glaucoma; Heart Rate; Humans; Intraocular Pressure; Levobunolol; Opt

1988

Other Studies

32 other studies available for dipivefrin and Intraocular Pressure

ArticleYear
Effects of topical adrenergic agents on prostaglandin E2-induced aqueous flare and intraocular pressure elevation in pigmented rabbits.
    Japanese journal of ophthalmology, 2016, Volume: 60, Issue:2

    Topics: Administration, Topical; Adrenergic Agonists; Animals; Aqueous Humor; Blood-Aqueous Barrier; Brimoni

2016
The effect of echothiophate on the biphasic response of rabbit ocular pressure to dipivefrin.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1982, Volume: 100, Issue:1

    Topics: Animals; Dose-Response Relationship, Drug; Echothiophate Iodide; Epinephrine; Intraocular Pressure;

1982
Drop attack in glaucoma. The Melbourne experience with topical miotics, adrenergic and neuronal blocking drops.
    Australian journal of ophthalmology, 1983, Volume: 11, Issue:3

    Topics: Echothiophate Iodide; Epinephrine; Glaucoma; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Mio

1983
Experience with dipivalyl epinephrine. Its effectiveness, alone or in combination, and its side effects.
    Australian journal of ophthalmology, 1983, Volume: 11, Issue:3

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma; Glaucoma, Open-Angle; Headache; Humans; Intraocula

1983
Combined timolol and epinephrine therapy for open angle glaucoma.
    Survey of ophthalmology, 1983, Volume: 28 Suppl

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Pilocarp

1983
Enzymatic and nonenzymatic hydrolysis of D,L-dipivefrin.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1984, Volume: 102, Issue:3

    Topics: Animals; Aorta; Aqueous Humor; Catalysis; Cholinesterase Inhibitors; Chromatography, High Pressure L

1984
Cardiovascular effects of epinephrine and dipivefrin in patients using timolol: a single-dose study.
    Canadian journal of ophthalmology. Journal canadien d'ophtalmologie, 1984, Volume: 19, Issue:1

    Topics: Aged; Aqueous Humor; Arrhythmias, Cardiac; Blood Pressure; Double-Blind Method; Drug Interactions; D

1984
An advance in ophthalmic pharmacology. The use of the epinephrine pro-drug dipivalyl epinephrine in the treatment of glaucoma.
    Journal of the American Optometric Association, 1982, Volume: 53, Issue:9

    Topics: Cornea; Drug Administration Schedule; Epinephrine; Glaucoma, Open-Angle; Humans; Intraocular Pressur

1982
Timolol and dipivalyl epinephrine combination therapy.
    Australian journal of ophthalmology, 1982, Volume: 10, Issue:3

    Topics: Aged; Chronic Disease; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma, Ope

1982
[Treatment of glaucoma with a pilocarpine-dipivefrin combination (author's transl)].
    Klinische Monatsblatter fur Augenheilkunde, 1981, Volume: 178, Issue:3

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma; Humans; Intraocular Pressure; Pilocarpine

1981
Safety and effectiveness of concomitant administration of dipivefrin and timolol maleate.
    American journal of ophthalmology, 1981, Volume: 91, Issue:2

    Topics: Adult; Aged; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; Humans; Intraocular Pressure;

1981
[Comparison of 0.1% dipivalyl epinephrine and 1% epinephrine in patients with glaucoma or ocular hypertension].
    [Zhonghua yan ke za zhi] Chinese journal of ophthalmology, 1994, Volume: 30, Issue:2

    Topics: Adolescent; Adult; Epinephrine; Female; Glaucoma, Open-Angle; Humans; Intraocular Pressure; Male; Mi

1994
Transscleral neodymium:YAG laser cyclophotocoagulation for end-stage glaucoma, refractory glaucoma, and painful blind eyes.
    Ophthalmic surgery, 1993, Volume: 24, Issue:8

    Topics: Adult; Aged; Aged, 80 and over; Blindness; Ciliary Body; Epinephrine; Follow-Up Studies; Glaucoma; H

1993
Epithelial barrier function of the filtering bleb conjunctiva and the cornea after trabeculectomy with mitomycin C.
    Journal of glaucoma, 1996, Volume: 5, Issue:4

    Topics: Aged; Antibiotics, Antineoplastic; Conjunctiva; Cornea; Epinephrine; Epithelium; Female; Fluorescein

1996
A topical prostaglandin for glaucoma.
    The Medical letter on drugs and therapeutics, 1996, Nov-08, Volume: 38, Issue:987

    Topics: Administration, Topical; Adrenergic Agents; Adrenergic beta-Antagonists; Carbonic Anhydrase Inhibito

1996
Progressive normal-tension glaucoma. I. Analysis.
    Journal of glaucoma, 1996, Volume: 5, Issue:6

    Topics: Adrenergic Agonists; Adrenergic beta-Antagonists; Aged; Disease Progression; Epinephrine; Female; Gl

1996
Treatment of progressive normal-tension glaucoma.
    Journal of glaucoma, 1997, Volume: 6, Issue:6

    Topics: Administration, Topical; Adrenergic beta-Antagonists; Aged; Disease Progression; Epinephrine; Female

1997
An in-service investigation of the additive effect of topical adrenergic agonists and beta-blockers.
    Australian and New Zealand journal of ophthalmology, 1998, Volume: 26, Issue:3

    Topics: Administration, Topical; Adrenergic Agonists; Adrenergic beta-Antagonists; Adult; Aged; Aged, 80 and

1998
Development of glaucoma after phacoemulsification for removal of cataracts in dogs: 22 cases (1987-1997).
    Journal of the American Veterinary Medical Association, 2001, Jan-01, Volume: 218, Issue:1

    Topics: Animals; Antihypertensive Agents; Cataract; Dog Diseases; Dogs; Epinephrine; Female; Glaucoma; Intra

2001
Dipivefrin and echothiophate: contraindications to combined use.
    Archives of ophthalmology (Chicago, Ill. : 1960), 1979, Volume: 97, Issue:10

    Topics: Administration, Topical; Animals; Biotransformation; Drug Combinations; Drug Interactions; Echothiop

1979
External ocular toxicity of dipivalyl epinephrine.
    American journal of ophthalmology, 1979, Volume: 88, Issue:6

    Topics: Administration, Topical; Aged; Conjunctiva; Conjunctivitis; Drug Tolerance; Epinephrine; Eye Disease

1979
Effects of topical 1-epinephrine and dipivalyl epinephrine on intraocular pressure and pupil size in the normotensive and glaucomatous Beagle.
    American journal of veterinary research, 1978, Volume: 39, Issue:1

    Topics: Animals; Dog Diseases; Dogs; Epinephrine; Glaucoma; Intraocular Pressure; Ophthalmic Solutions; Pupi

1978
Long-term drift and timolol therapy: possible role for pulsed therapy.
    International ophthalmology, 1992, Volume: 16, Issue:4-5

    Topics: Aged; Aged, 80 and over; Drug Administration Schedule; Epinephrine; Humans; Intraocular Pressure; Lo

1992
Delayed filtering bleb encapsulation.
    Ophthalmic surgery, 1992, Volume: 23, Issue:1

    Topics: Epinephrine; Female; Follow-Up Studies; Glaucoma, Open-Angle; Glucocorticoids; Humans; Intraocular P

1992
Intraocular pressure-dependent retinal vascular change in adult chronic open-angle glaucoma patients.
    Ophthalmology, 1991, Volume: 98, Issue:7

    Topics: Adrenergic beta-Antagonists; Adult; Age Factors; Aged; Aged, 80 and over; Chronic Disease; Epinephri

1991
Ocular effects of dipivalyl esters of epinephrine and alpha-methylepinephrine.
    Experimental eye research, 1990, Volume: 51, Issue:5

    Topics: Animals; Dose-Response Relationship, Drug; Epinephrine; Female; Ganglionectomy; Intraocular Pressure

1990
The role of apraclonidine hydrochloride in laser therapy for glaucoma.
    Transactions of the American Ophthalmological Society, 1989, Volume: 87

    Topics: Acetazolamide; Adult; Aged; Animals; Clonidine; Epinephrine; Female; Glaucoma, Open-Angle; Humans; I

1989
Drugs and glaucoma.
    American family physician, 1986, Volume: 34, Issue:1

    Topics: Adrenergic beta-Antagonists; Betaxolol; Carbonic Anhydrase Inhibitors; Drug Combinations; Drug Impla

1986
pH dependency of effect of topically applied dipivefrine hydrochloride on intraocular pressure and pupil size in rabbits: comparative studies with epinephrine.
    Japanese journal of ophthalmology, 1988, Volume: 32, Issue:2

    Topics: Administration, Topical; Animals; Blinking; Dose-Response Relationship, Drug; Epinephrine; Hydrogen;

1988
[Guanethidine/dipivefrin and pilocarpine in the treatment of increased intraocular pressure].
    Klinische Monatsblatter fur Augenheilkunde, 1987, Volume: 190, Issue:2

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pres

1987
Therapeutic response interactions between timolol maleate and dipivefrin hydrochloride.
    Australian and New Zealand journal of ophthalmology, 1987, Volume: 15, Issue:2

    Topics: Aged; Aged, 80 and over; Drug Synergism; Drug Therapy, Combination; Epinephrine; Female; Glaucoma; H

1987
[Experiences with the effectiveness and tolerance of guanethidine/dipivefrin-AT in the treatment of increased intraocular pressure].
    Klinische Monatsblatter fur Augenheilkunde, 1986, Volume: 188, Issue:1

    Topics: Drug Therapy, Combination; Epinephrine; Glaucoma, Open-Angle; Guanethidine; Humans; Intraocular Pres

1986