diphenyleneiodonium has been researched along with Parkinson Disease in 2 studies
diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.
Parkinson Disease: A progressive, degenerative neurologic disease characterized by a TREMOR that is maximal at rest, retropulsion (i.e. a tendency to fall backwards), rigidity, stooped posture, slowness of voluntary movements, and a masklike facial expression. Pathologic features include loss of melanin containing neurons in the substantia nigra and other pigmented nuclei of the brainstem. LEWY BODIES are present in the substantia nigra and locus coeruleus but may also be found in a related condition (LEWY BODY DISEASE, DIFFUSE) characterized by dementia in combination with varying degrees of parkinsonism. (Adams et al., Principles of Neurology, 6th ed, p1059, pp1067-75)
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Wang, Q | 1 |
| Qian, L | 1 |
| Chen, SH | 1 |
| Chu, CH | 1 |
| Wilson, B | 2 |
| Oyarzabal, E | 1 |
| Ali, S | 1 |
| Robinson, B | 1 |
| Rao, D | 1 |
| Hong, JS | 2 |
| Gao, HM | 1 |
| Zhang, F | 1 |
| Zhou, H | 1 |
| Kam, W | 1 |
2 other studies available for diphenyleneiodonium and Parkinson Disease
| Article | Year |
|---|---|
Post-treatment with an ultra-low dose of NADPH oxidase inhibitor diphenyleneiodonium attenuates disease progression in multiple Parkinson's disease models.
Topics: Animals; Disease Models, Animal; Disease Progression; Dopaminergic Neurons; Enzyme Inhibitors; Mice, | 2015 |
Neuroinflammation and α-synuclein dysfunction potentiate each other, driving chronic progression of neurodegeneration in a mouse model of Parkinson's disease.
Topics: alpha-Synuclein; Amidines; Animals; Animals, Genetically Modified; Benzylamines; Disease Models, Ani | 2011 |