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diphenyleneiodonium and Pancreatic Neoplasms

diphenyleneiodonium has been researched along with Pancreatic Neoplasms in 5 studies

diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.

Pancreatic Neoplasms: Tumors or cancer of the PANCREAS. Depending on the types of ISLET CELLS present in the tumors, various hormones can be secreted: GLUCAGON from PANCREATIC ALPHA CELLS; INSULIN from PANCREATIC BETA CELLS; and SOMATOSTATIN from the SOMATOSTATIN-SECRETING CELLS. Most are malignant except the insulin-producing tumors (INSULINOMA).

Research Excerpts

ExcerptRelevanceReference
"Treatment of pancreatic cancer cells with TGF-β induced Nox4 expression, indicating that Nox4 represents a major source for ROS production."1.39Nox4-derived ROS signaling contributes to TGF-β-induced epithelial-mesenchymal transition in pancreatic cancer cells. ( Hiraga, R; Kamata, T; Kato, M; Miyagawa, S, 2013)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's2 (40.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Liu, M1
Wang, D1
Luo, Y1
Hu, L1
Bi, Y1
Ji, J1
Huang, H1
Wang, G1
Zhu, L1
Ma, J1
Kim, E1
Luo, CK1
Abbruzzese, JL1
Li, X1
Yang, VW1
Li, Z1
Lu, W1
Hiraga, R1
Kato, M1
Miyagawa, S1
Kamata, T2
Wu, Y1
Meitzler, JL1
Antony, S1
Juhasz, A1
Lu, J1
Jiang, G1
Liu, H1
Hollingshead, M1
Haines, DC1
Butcher, D1
Panter, MS1
Roy, K1
Doroshow, JH1
Groth, S1
Schulze, M1
Kalthoff, H1
Fändrich, F1
Ungefroren, H1
Mochizuki, T1
Furuta, S1
Mitsushita, J1
Shang, WH1
Ito, M1
Yokoo, Y1
Yamaura, M1
Ishizone, S1
Nakayama, J1
Konagai, A1
Hirose, K1
Kiyosawa, K1

Other Studies

5 other studies available for diphenyleneiodonium and Pancreatic Neoplasms

ArticleYear
Selective killing of cancer cells harboring mutant RAS by concomitant inhibition of NADPH oxidase and glutathione biosynthesis.
    Cell death & disease, 2021, 02-16, Volume: 12, Issue:2

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Pancreatic Ductal; Cell Death; C

2021
Nox4-derived ROS signaling contributes to TGF-β-induced epithelial-mesenchymal transition in pancreatic cancer cells.
    Anticancer research, 2013, Volume: 33, Issue:10

    Topics: Acetylcysteine; Antigens, CD; Cadherins; Carcinoma, Pancreatic Ductal; Cell Line, Tumor; Enzyme Indu

2013
Dual oxidase 2 and pancreatic adenocarcinoma: IFN-γ-mediated dual oxidase 2 overexpression results in H2O2-induced, ERK-associated up-regulation of HIF-1α and VEGF-A.
    Oncotarget, 2016, 10-18, Volume: 7, Issue:42

    Topics: Adenocarcinoma; Animals; Cell Line, Tumor; Dual Oxidases; Extracellular Signal-Regulated MAP Kinases

2016
Adhesion and Rac1-dependent regulation of biglycan gene expression by transforming growth factor-beta. Evidence for oxidative signaling through NADPH oxidase.
    The Journal of biological chemistry, 2005, Sep-30, Volume: 280, Issue:39

    Topics: Biglycan; Carcinoma; Cell Adhesion; Cell Line, Tumor; Cytochalasin D; Enzyme Activation; Enzyme Inhi

2005
Inhibition of NADPH oxidase 4 activates apoptosis via the AKT/apoptosis signal-regulating kinase 1 pathway in pancreatic cancer PANC-1 cells.
    Oncogene, 2006, Jun-22, Volume: 25, Issue:26

    Topics: Adenocarcinoma; Apoptosis; Cell Line, Tumor; Enzyme Inhibitors; Humans; MAP Kinase Kinase Kinase 5;

2006