Page last updated: 2024-10-26

diphenyleneiodonium and Neoplasms

diphenyleneiodonium has been researched along with Neoplasms in 5 studies

diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Since Warburg's observation that most cancers exhibit elevated glycolysis, decades of research have attempted to reduce tumor glucose utilization as a therapeutic approach."2.61A Tumor Agnostic Therapeutic Strategy for Hexokinase 1-Null/Hexokinase 2-Positive Cancers. ( Herschman, HR; Xu, S, 2019)
"NOX4 knockdown in ovarian cancer cells decreased the levels of VEGF and HIF-1 alpha and tumor angiogenesis."1.34Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor. ( Jiang, BH; Liu, LZ; Meng, Q; Rojanasakul, Y; Wang, XR; Xia, C, 2007)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's3 (60.00)29.6817
2010's1 (20.00)24.3611
2020's1 (20.00)2.80

Authors

AuthorsStudies
Diamandis, P1
Wildenhain, J1
Clarke, ID1
Sacher, AG1
Graham, J1
Bellows, DS1
Ling, EK1
Ward, RJ1
Jamieson, LG1
Tyers, M1
Dirks, PB1
Monzur, S1
Hassan, G1
Afify, SM1
Kumon, K1
Mansour, H1
Nawara, HM1
Sheta, M1
Abu Quora, HA1
Zahra, MH1
Xu, Y1
Fu, X1
Seno, A1
Wikström, P1
Szekeres, FLM1
Seno, M1
Xu, S1
Herschman, HR1
Song, JD1
Kim, KM1
Kim, KH1
Kim, CD1
Kim, JM1
Yoo, YH1
Park, YC1
Xia, C1
Meng, Q1
Liu, LZ1
Rojanasakul, Y1
Wang, XR1
Jiang, BH1

Reviews

1 review available for diphenyleneiodonium and Neoplasms

ArticleYear
A Tumor Agnostic Therapeutic Strategy for Hexokinase 1-Null/Hexokinase 2-Positive Cancers.
    Cancer research, 2019, Dec-01, Volume: 79, Issue:23

    Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Cell Line, Tumor; Glycolysis; Hexokinase; H

2019

Other Studies

4 other studies available for diphenyleneiodonium and Neoplasms

ArticleYear
Chemical genetics reveals a complex functional ground state of neural stem cells.
    Nature chemical biology, 2007, Volume: 3, Issue:5

    Topics: Animals; Cell Survival; Cells, Cultured; Mice; Molecular Structure; Neoplasms; Neurons; Pharmaceutic

2007
Diphenyleneiodonium efficiently inhibits the characteristics of a cancer stem cell model derived from induced pluripotent stem cells.
    Cell biochemistry and function, 2022, Volume: 40, Issue:3

    Topics: Antineoplastic Agents; Cell Line, Tumor; Cell Proliferation; Induced Pluripotent Stem Cells; NADPH O

2022
Differential role of diphenyleneiodonium, a flavoenzyme inhibitor, on p53-dependent and -independent cell cycle progression.
    International journal of oncology, 2008, Volume: 33, Issue:6

    Topics: Cell Cycle; Cell Proliferation; Cell Survival; Cyclin D1; Cyclin-Dependent Kinase Inhibitor p21; Dos

2008
Reactive oxygen species regulate angiogenesis and tumor growth through vascular endothelial growth factor.
    Cancer research, 2007, Nov-15, Volume: 67, Issue:22

    Topics: Animals; Cell Line, Tumor; Chickens; Chorioallantoic Membrane; Electrons; Female; Humans; Hydrogen P

2007