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diphenyleneiodonium and Muscular Diseases

diphenyleneiodonium has been researched along with Muscular Diseases in 3 studies

diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.

Muscular Diseases: Acquired, familial, and congenital disorders of SKELETAL MUSCLE and SMOOTH MUSCLE.

Research Excerpts

ExcerptRelevanceReference
" At the highest dose, muscle fatigue, lactic acidosis and an over-utilization of phosphocreatine was observed in the gastrocnemius muscle during mild stimulation of 1 Hz frequency."3.67An animal model of mitochondrial myopathy: a biochemical and physiological investigation of rats treated in vivo with the NADH-CoQ reductase inhibitor, diphenyleneiodonium. ( Brosnan, MJ; Challiss, RA; Clark, JB; Cooper, JM; Hayes, DJ; Morgan-Hughes, JA; Petty, RK; Radda, GK; Shoubridge, EA, 1988)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19903 (100.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Cooper, JM2
Petty, RK2
Hayes, DJ3
Challiss, RA1
Brosnan, MJ1
Shoubridge, EA2
Radda, GK1
Morgan-Hughes, JA3
Clark, JB3
Byrne, E1

Other Studies

3 other studies available for diphenyleneiodonium and Muscular Diseases

ArticleYear
An animal model of mitochondrial myopathy: a biochemical and physiological investigation of rats treated in vivo with the NADH-CoQ reductase inhibitor, diphenyleneiodonium.
    Journal of the neurological sciences, 1988, Volume: 83, Issue:2-3

    Topics: Acidosis; Animals; Dose-Response Relationship, Drug; Male; Mitochondria, Muscle; Muscles; Muscular D

1988
Chronic administration of the oral hypoglycaemic agent diphenyleneiodonium to rats. An animal model of impaired oxidative phosphorylation (mitochondrial myopathy).
    Biochemical pharmacology, 1988, Feb-15, Volume: 37, Issue:4

    Topics: Administration, Oral; Animals; Cytochromes; Disease Models, Animal; Hypoglycemic Agents; Male; Mitoc

1988
Experimentally induced defects of mitochondrial metabolism in rat skeletal muscle. Biological effects of the NADH: coenzyme Q reductase inhibitor diphenyleneiodonium.
    The Biochemical journal, 1985, Jul-01, Volume: 229, Issue:1

    Topics: Animals; Disease Models, Animal; Electric Stimulation; Magnetic Resonance Spectroscopy; Mitochondria

1985