diphenyleneiodonium has been researched along with Leukemia, Myelogenous, Chronic, BCR-ABL Positive in 2 studies
diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.
Leukemia, Myelogenous, Chronic, BCR-ABL Positive: Clonal hematopoetic disorder caused by an acquired genetic defect in PLURIPOTENT STEM CELLS. It starts in MYELOID CELLS of the bone marrow, invades the blood and then other organs. The condition progresses from a stable, more indolent, chronic phase (LEUKEMIA, MYELOID, CHRONIC PHASE) lasting up to 7 years, to an advanced phase composed of an accelerated phase (LEUKEMIA, MYELOID, ACCELERATED PHASE) and BLAST CRISIS.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Patients with chronic myelogenous leukemia (CML) in blast crisis have a poor response to tyrosine kinase inhibitors designed to inhibit the breakpoint cluster region-v-Abelson murine leukemia viral oncogene homolog 1 (BCR-ABL1) oncogene." | 1.38 | Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia. ( Amin, HM; Arlinghaus, RB; Ban, K; Chandra, J; Gao, Y; Irwin, ME; Shi, P; Singh, MM, 2012) |
| "Bcr-Abl causes chronic myelogenous leukemia, a myeloproliferative disorder characterized by clonal expansion of hematopoietic progenitor cells." | 1.35 | Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway. ( Cotter, TG; Naughton, R; Quiney, C; Turner, SD, 2009) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (50.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Naughton, R | 1 |
| Quiney, C | 1 |
| Turner, SD | 1 |
| Cotter, TG | 1 |
| Singh, MM | 1 |
| Irwin, ME | 1 |
| Gao, Y | 1 |
| Ban, K | 1 |
| Shi, P | 1 |
| Arlinghaus, RB | 1 |
| Amin, HM | 1 |
| Chandra, J | 1 |
2 other studies available for diphenyleneiodonium and Leukemia, Myelogenous, Chronic, BCR-ABL Positive
| Article | Year |
|---|---|
Bcr-Abl-mediated redox regulation of the PI3K/AKT pathway.
Topics: Apoptosis; beta Catenin; Cell Line, Tumor; Fusion Proteins, bcr-abl; Glycogen Synthase Kinase 3; Gly | 2009 |
Inhibition of the NADPH oxidase regulates heme oxygenase 1 expression in chronic myeloid leukemia.
Topics: Animals; Blast Crisis; Bone Marrow; Cell Line, Tumor; Heme Oxygenase-1; Humans; Leukemia, Myelogenou | 2012 |