diphenyleneiodonium has been researched along with Granulomatous Disease, Chronic in 9 studies
diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.
Granulomatous Disease, Chronic: A defect of leukocyte function in which phagocytic cells ingest but fail to digest bacteria, resulting in recurring bacterial infections with granuloma formation. When chronic granulomatous disease is caused by mutations in the CYBB gene, the condition is inherited in an X-linked recessive pattern. When chronic granulomatous disease is caused by CYBA, NCF1, NCF2, or NCF4 gene mutations, the condition is inherited in an autosomal recessive pattern.
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 3 (33.33) | 18.2507 |
| 2000's | 5 (55.56) | 29.6817 |
| 2010's | 1 (11.11) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Harfi, I | 1 |
| D'Hondt, S | 1 |
| Sariban, E | 1 |
| Dri, P | 2 |
| Presani, G | 1 |
| Perticarari, S | 1 |
| Albèri, L | 1 |
| Prodan, M | 1 |
| Decleva, E | 2 |
| Rada, BK | 1 |
| Geiszt, M | 1 |
| Van Bruggen, R | 1 |
| Nemet, K | 1 |
| Roos, D | 1 |
| Ligeti, E | 1 |
| Menegazzi, R | 1 |
| Busetto, S | 1 |
| Patriarca, P | 1 |
| Fuchs, TA | 1 |
| Abed, U | 1 |
| Goosmann, C | 1 |
| Hurwitz, R | 1 |
| Schulze, I | 1 |
| Wahn, V | 1 |
| Weinrauch, Y | 1 |
| Brinkmann, V | 1 |
| Zychlinsky, A | 1 |
| Demaurex, N | 1 |
| Downey, GP | 1 |
| Waddell, TK | 1 |
| Grinstein, S | 1 |
| Yan, SR | 1 |
| Berton, G | 1 |
| Christin, L | 1 |
| Wysong, DR | 1 |
| Meshulam, T | 1 |
| Wang, S | 1 |
| Diamond, RD | 1 |
| Yamashita, K | 1 |
| Arai, T | 1 |
| Fukuda, K | 1 |
| Mori, H | 1 |
| Ishii, H | 1 |
| Nishioka, M | 1 |
| Tajima, K | 1 |
| Makino, K | 1 |
| Sasada, M | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Neutrophil Extracellular Trap Formation in Patients Undergoing Bone Marrow Transplant[NCT01735565] | 23 participants (Actual) | Observational | 2012-06-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
9 other studies available for diphenyleneiodonium and Granulomatous Disease, Chronic
| Article | Year |
|---|---|
iPLA
Topics: Aspergillus fumigatus; Exocytosis; Female; Granulomatous Disease, Chronic; Humans; Male; Neutrophils | 2019 |
Measurement of phagosomal pH of normal and CGD-like human neutrophils by dual fluorescence flow cytometry.
Topics: Candida albicans; Enzyme Inhibitors; Flow Cytometry; Fluorescein; Fluorescent Dyes; Fungal Proteins; | 2002 |
Calcium signalling is altered in myeloid cells with a deficiency in NADPH oxidase activity.
Topics: Calcium; Calcium Signaling; Cell Line; Cells, Cultured; Enzyme Inhibitors; Granulomatous Disease, Ch | 2003 |
Common methodology is inadequate for studies on the microbicidal activity of neutrophils.
Topics: Biological Assay; Candida albicans; Cells, Cultured; Colony Count, Microbial; Enzyme Inhibitors; Esc | 2006 |
Novel cell death program leads to neutrophil extracellular traps.
Topics: Antibodies; Apoptosis; Catalase; Cell Death; Cell Survival; Chromatin; Cytoplasmic Granules; Enzyme | 2007 |
Intracellular pH regulation during spreading of human neutrophils.
Topics: Actin Cytoskeleton; CD18 Antigens; Cell Adhesion; Cell Movement; Cell Size; Cytochalasin D; Cytosol; | 1996 |
Regulation of Src family tyrosine kinase activities in adherent human neutrophils. Evidence that reactive oxygen intermediates produced by adherent neutrophils increase the activity of the p58c-fgr and p53/56lyn tyrosine kinases.
Topics: Catalase; Cell Adhesion; Cell Compartmentation; Cytoskeletal Proteins; Enzyme Inhibitors; Gene Expre | 1996 |
Mechanisms and target sites of damage in killing of Candida albicans hyphae by human polymorphonuclear neutrophils.
Topics: Adenosine Triphosphate; Amino Acids; Biotinylation; Candida albicans; Cell Wall; DNA Damage; DNA, Fu | 1997 |
6-formylpterin intracellularly generates hydrogen peroxide and restores the impaired bactericidal activity of human neutrophils.
Topics: Adult; Blood Bactericidal Activity; Electron Spin Resonance Spectroscopy; Enzyme Inhibitors; Escheri | 2001 |