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diphenyleneiodonium and Cardiomegaly

diphenyleneiodonium has been researched along with Cardiomegaly in 2 studies

diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.

Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.

Research Excerpts

ExcerptRelevanceReference
"Upregulation of Nox4 by hypertrophic stimuli and aging induces oxidative stress, apoptosis and LV dysfunction, in part because of mitochondrial insufficiency caused by increased O(2)(-) production and consequent cysteine oxidation in mitochondrial proteins."3.76Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. ( Ago, T; Fu, C; Kuroda, J; Li, H; Pain, J; Sadoshima, J, 2010)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's2 (100.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ago, T1
Kuroda, J1
Pain, J1
Fu, C1
Li, H1
Sadoshima, J1
Wu, R1
Yin, D1
Sadekova, N1
Deschepper, CF1
de Champlain, J1
Girouard, H1

Other Studies

2 other studies available for diphenyleneiodonium and Cardiomegaly

ArticleYear
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.
    Circulation research, 2010, Apr-16, Volume: 106, Issue:7

    Topics: Aconitate Hydratase; Aging; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Cells, Cultured; C

2010
Protective effects of aspirin from cardiac hypertrophy and oxidative stress in cardiomyopathic hamsters.
    Oxidative medicine and cellular longevity, 2012, Volume: 2012

    Topics: Animals; Aorta; Aspirin; Blood Pressure; Body Weight; Cardiomegaly; Cardiomyopathies; Cardiotonic Ag

2012
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