diphenyleneiodonium and Cardiomegaly
diphenyleneiodonium has been researched along with Cardiomegaly in 2 studies
diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.
Cardiomegaly: Enlargement of the HEART, usually indicated by a cardiothoracic ratio above 0.50. Heart enlargement may involve the right, the left, or both HEART VENTRICLES or HEART ATRIA. Cardiomegaly is a nonspecific symptom seen in patients with chronic systolic heart failure (HEART FAILURE) or several forms of CARDIOMYOPATHIES.
Research Excerpts
Excerpt | Relevance | Reference |
---|---|---|
"Upregulation of Nox4 by hypertrophic stimuli and aging induces oxidative stress, apoptosis and LV dysfunction, in part because of mitochondrial insufficiency caused by increased O(2)(-) production and consequent cysteine oxidation in mitochondrial proteins." | 3.76 | Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. ( Ago, T; Fu, C; Kuroda, J; Li, H; Pain, J; Sadoshima, J, 2010) |
Research
Studies (2)
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (100.00) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors
Authors | Studies |
---|---|
Ago, T | 1 |
Kuroda, J | 1 |
Pain, J | 1 |
Fu, C | 1 |
Li, H | 1 |
Sadoshima, J | 1 |
Wu, R | 1 |
Yin, D | 1 |
Sadekova, N | 1 |
Deschepper, CF | 1 |
de Champlain, J | 1 |
Girouard, H | 1 |
Other Studies
2 other studies available for diphenyleneiodonium and Cardiomegaly
Article | Year |
---|---|
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.
Topics: Aconitate Hydratase; Aging; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Cells, Cultured; C | 2010 |
Protective effects of aspirin from cardiac hypertrophy and oxidative stress in cardiomyopathic hamsters.
Topics: Animals; Aorta; Aspirin; Blood Pressure; Body Weight; Cardiomegaly; Cardiomyopathies; Cardiotonic Ag | 2012 |