diphenyleneiodonium has been researched along with Cardiac Hypertrophy in 2 studies
diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.
Cardiac Hypertrophy: Enlargement of the HEART due to chamber HYPERTROPHY, an increase in wall thickness without an increase in the number of cells (MYOCYTES, CARDIAC). It is the result of increase in myocyte size, mitochondrial and myofibrillar mass, as well as changes in extracellular matrix.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Upregulation of Nox4 by hypertrophic stimuli and aging induces oxidative stress, apoptosis and LV dysfunction, in part because of mitochondrial insufficiency caused by increased O(2)(-) production and consequent cysteine oxidation in mitochondrial proteins." | 3.76 | Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. ( Ago, T; Fu, C; Kuroda, J; Li, H; Pain, J; Sadoshima, J, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 2 (100.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ago, T | 1 |
| Kuroda, J | 1 |
| Pain, J | 1 |
| Fu, C | 1 |
| Li, H | 1 |
| Sadoshima, J | 1 |
| Wu, R | 1 |
| Yin, D | 1 |
| Sadekova, N | 1 |
| Deschepper, CF | 1 |
| de Champlain, J | 1 |
| Girouard, H | 1 |
2 other studies available for diphenyleneiodonium and Cardiac Hypertrophy
| Article | Year |
|---|---|
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.
Topics: Aconitate Hydratase; Aging; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Cells, Cultured; C | 2010 |
Protective effects of aspirin from cardiac hypertrophy and oxidative stress in cardiomyopathic hamsters.
Topics: Animals; Aorta; Aspirin; Blood Pressure; Body Weight; Cardiomegaly; Cardiomyopathies; Cardiotonic Ag | 2012 |