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diphenyleneiodonium and Aging

diphenyleneiodonium has been researched along with Aging in 3 studies

diphenyleneiodonium: structure in first source; NADPH oxidase inhibitor
dibenziodolium : An organic cation that is fluorene in which the methylene group is replaced by a positively charged iodine.

Aging: The gradual irreversible changes in structure and function of an organism that occur as a result of the passage of time.

Research Excerpts

ExcerptRelevanceReference
"Upregulation of Nox4 by hypertrophic stimuli and aging induces oxidative stress, apoptosis and LV dysfunction, in part because of mitochondrial insufficiency caused by increased O(2)(-) production and consequent cysteine oxidation in mitochondrial proteins."3.76Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes. ( Ago, T; Fu, C; Kuroda, J; Li, H; Pain, J; Sadoshima, J, 2010)
" Superoxide anion (O(2)(-)) is a major determinant of nitric oxide (NO) bioavailability and thus endothelial function."1.31Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction. ( Brosnan, MJ; Dominiczak, AF; Graham, D; Hamilton, CA; McIntyre, M, 2001)

Research

Studies (3)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's2 (66.67)29.6817
2010's1 (33.33)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Ago, T1
Kuroda, J1
Pain, J1
Fu, C1
Li, H1
Sadoshima, J1
Hamilton, CA1
Brosnan, MJ1
McIntyre, M1
Graham, D1
Dominiczak, AF1
Wu, R1
Millette, E1
Wu, L1
de Champlain, J1

Other Studies

3 other studies available for diphenyleneiodonium and Aging

ArticleYear
Upregulation of Nox4 by hypertrophic stimuli promotes apoptosis and mitochondrial dysfunction in cardiac myocytes.
    Circulation research, 2010, Apr-16, Volume: 106, Issue:7

    Topics: Aconitate Hydratase; Aging; Animals; Apoptosis; Cardiomegaly; Cell Proliferation; Cells, Cultured; C

2010
Superoxide excess in hypertension and aging: a common cause of endothelial dysfunction.
    Hypertension (Dallas, Tex. : 1979), 2001, Volume: 37, Issue:2 Pt 2

    Topics: Acetophenones; Aging; Animals; Aorta; Blood Pressure; Carotid Arteries; Endothelium, Vascular; Enzym

2001
Enhanced superoxide anion formation in vascular tissues from spontaneously hypertensive and desoxycorticosterone acetate-salt hypertensive rats.
    Journal of hypertension, 2001, Volume: 19, Issue:4

    Topics: Aging; Animals; Aorta; Blood Pressure; Cells, Cultured; Desoxycorticosterone; Ditiocarb; Enzyme Inhi

2001