diphenylamine has been researched along with Melanoma in 15 studies
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 3 (20.00) | 29.6817 |
| 2010's | 11 (73.33) | 24.3611 |
| 2020's | 1 (6.67) | 2.80 |
| Authors | Studies |
|---|---|
| Mergener, S; Peña-Llopis, S; Siveke, JT | 1 |
| Arunan, V; Beloueche-Babari, M; Eykyn, TR; Falck Miniotis, M; Leach, MO; Marais, R; Workman, P | 1 |
| Biffoni, M; De Maria, R; Duranti, E; Eramo, A; Fecchi, K; Lotti, F; Martinetti, D; Memeo, L; Milella, M; Pagliuca, A; Pilozzi, E; Salvati, V; Sette, G | 1 |
| Fellmann, C; Gadal, S; Ishii, N; Joseph, E; Kastenhuber, E; Lito, P; Lowe, S; Lukacs, C; Miura, T; Morikami, K; Ohara, K; Rosen, N; Saborowski, A; Saborowski, M; Solomon, M; Yue, J | 1 |
| Chen, BJ; Goddard, N; Litvin, O; Oh, NL; Pe'er, D; Pratilas, C; Rocco, M; Schild, T; Schwartz, S; Wan, Z | 1 |
| Andersen, NJ; Boguslawski, EB; Chambers, CM; Duesbery, NS; Kuk, CY | 1 |
| Cossu, I; Dono, M; Gualco, M; Manzini, C; Mingari, MC; Moretta, L; Pietra, G; Queirolo, P; Spagnolo, F; Venè, R; Zupo, S | 1 |
| Beltran, P; Caenepeel, S; Cajulis, E; Cooke, K; Coxon, A; Huang, G; Hughes, PE; Kendall, R; Moreno, BH; Parisi, G; Ribas, A; Robert, L; Wadsworth, S | 1 |
| Anichini, A; Bellacosa, A; Benassi, B; Chiaretti, S; Ciuffreda, L; Cognetti, F; Del Bufalo, D; Desideri, M; Di Sanza, C; Foà, R; Milella, M; Ricciardi, MR; Stoppacciaro, A; Tafuri, A; Tavolaro, S; Zupi, G | 1 |
| Aboagye, EO; Arstad, E; Leyton, J; Nguyen, QD; Perumal, M; Robins, E; Smith, G; Zhao, Y | 1 |
| Boni, A; Cogdill, AP; Dang, P; Ferrone, CR; Fisher, DE; Flaherty, KT; Lawrence, DP; Njauw, CN; Sloss, CM; Tsao, H; Udayakumar, D; Wargo, JA | 1 |
| Boasberg, PD; Bodkin, D; Daniels, GA; Garrett, CR; Redfern, CH; Ricart, AD | 1 |
| Anichini, A; Bergamo, P; Biagioni, F; Blandino, G; Cesta Incani, U; Ciuffreda, L; Cognetti, F; De Maria, R; Del Bufalo, D; Desideri, M; Di Sanza, C; Eramo, A; Falcone, I; McCubrey, JA; Milella, M; Orlandi, A; Passeri, D; Ricciardi, MR; Sabapathy, K; Sette, G; Tafuri, A | 1 |
| Nickoloff, BJ; Qin, J; Xin, H | 1 |
| Blasberg, R; Cai, S; Larson, S; Lobo, J; Moroz, M; Pratilas, CA; Rosen, N; Santos, E; Sebolt-Leopold, J; Solit, DB | 1 |
1 trial(s) available for diphenylamine and Melanoma
| Article | Year |
|---|---|
Pilot study of PD-0325901 in previously treated patients with advanced melanoma, breast cancer, and colon cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents; Benzamides; Breast Neoplasms; Cohort Studies; Colonic Neoplasms; Diphenylamine; Early Termination of Clinical Trials; Extracellular Signal-Regulated MAP Kinases; Eye Diseases; Female; Humans; Male; Melanoma; Middle Aged; Musculoskeletal Diseases; Neoplasm Staging; Neurotoxicity Syndromes; Pilot Projects | 2011 |
14 other study(ies) available for diphenylamine and Melanoma
| Article | Year |
|---|---|
Monosomy 3 Is Linked to Resistance to MEK Inhibitors in Uveal Melanoma.
Topics: Cell Line, Tumor; Chromosomes, Human, Pair 3; Diphenylamine; DNA Copy Number Variations; Drug Resistance, Neoplasm; Eukaryotic Initiation Factor-2; Gene Expression Regulation, Neoplastic; Humans; MAP Kinase Signaling System; Melanoma; Mitogen-Activated Protein Kinase Kinases; Monosomy; Protein Kinase Inhibitors; Pyridones; Pyrimidinones; Sulfonamides; Survival Analysis; Tumor Suppressor Proteins; Ubiquitin Thiolesterase; Uveal Neoplasms | 2021 |
MEK1/2 inhibition decreases lactate in BRAF-driven human cancer cells.
Topics: Animals; Antineoplastic Agents; Benzamides; Benzimidazoles; Cell Cycle Checkpoints; Cell Line, Tumor; Cell Proliferation; Deoxyglucose; Diphenylamine; Female; Gene Knockdown Techniques; Glucose; Hexokinase; Humans; Lactic Acid; MAP Kinase Kinase 1; MAP Kinase Kinase 2; Melanoma; Mice; Mutation, Missense; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-myc; RNA, Small Interfering; Tumor Burden; Xenograft Model Antitumor Assays | 2013 |
Mek inhibition results in marked antitumor activity against metastatic melanoma patient-derived melanospheres and in melanosphere-generated xenografts.
Topics: Animals; Apoptosis; Benzamides; Diphenylamine; Female; MAP Kinase Kinase Kinases; Melanoma; Mice; Mice, Inbred NOD; Mice, Nude; Mice, SCID; Protein Kinase Inhibitors; Random Allocation; Signal Transduction; Spheroids, Cellular; Xenograft Model Antitumor Assays | 2013 |
Disruption of CRAF-mediated MEK activation is required for effective MEK inhibition in KRAS mutant tumors.
Topics: Animals; Benzamides; Cell Line; Coumarins; Diphenylamine; Drug Resistance, Neoplasm; Extracellular Signal-Regulated MAP Kinases; HEK293 Cells; Humans; Indoles; MAP Kinase Kinase 1; MAP Kinase Signaling System; Melanoma; Mice; Mice, Nude; Phosphorylation; Protein Kinase Inhibitors; Proto-Oncogene Proteins; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins p21(ras); Pyridones; Pyrimidinones; raf Kinases; ras Proteins; RNA Interference; RNA, Small Interfering; Sulfonamides; Surface Plasmon Resonance; TNF Receptor-Associated Factor 3; Vemurafenib | 2014 |
Interferon α/β Enhances the Cytotoxic Response of MEK Inhibition in Melanoma.
Topics: Antineoplastic Agents; Benzamides; Cell Line, Tumor; Cell Survival; Cluster Analysis; Diphenylamine; Gene Expression Profiling; Gene Expression Regulation, Neoplastic; Humans; Interferon-alpha; Interferon-beta; MAP Kinase Signaling System; Melanoma; Microphthalmia-Associated Transcription Factor; Models, Genetic; Mutation; Oligonucleotide Array Sequence Analysis; STAT1 Transcription Factor | 2015 |
Combined inhibition of MEK and mTOR has a synergic effect on angiosarcoma tumorgrafts.
Topics: Animals; Antineoplastic Combined Chemotherapy Protocols; Benzamides; Cell Line, Tumor; Diphenylamine; Dogs; Dose-Response Relationship, Drug; Drug Synergism; Hemangiosarcoma; Humans; Melanoma; Mice; Mitogen-Activated Protein Kinase Kinases; Sirolimus; TOR Serine-Threonine Kinases; Xenograft Model Antitumor Assays | 2015 |
Cytokines can counteract the inhibitory effect of MEK-i on NK-cell function.
Topics: Acrylonitrile; Aniline Compounds; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diphenylamine; Down-Regulation; Flow Cytometry; Humans; Immunotherapy; Indoles; Interleukin-15; Interleukin-2; Killer Cells, Natural; Melanoma; Neoplasm Recurrence, Local; Oncogenes; Proto-Oncogene Proteins B-raf; Signal Transduction; Skin Neoplasms; Sulfonamides; Vemurafenib | 2016 |
MAPK pathway inhibition induces MET and GAB1 levels, priming BRAF mutant melanoma for rescue by hepatocyte growth factor.
Topics: Adaptor Proteins, Signal Transducing; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Cell Line, Tumor; Dipeptides; Diphenylamine; Drug Resistance, Neoplasm; Female; Hepatocyte Growth Factor; Humans; Indoles; MAP Kinase Signaling System; Melanoma; Mice; Mice, Nude; Protein Kinase Inhibitors; Proto-Oncogene Proteins B-raf; Proto-Oncogene Proteins c-met; Pyridones; Sulfonamides; Triazoles; Vemurafenib; Xenograft Model Antitumor Assays | 2017 |
Growth-inhibitory and antiangiogenic activity of the MEK inhibitor PD0325901 in malignant melanoma with or without BRAF mutations.
Topics: Angiogenesis Inhibitors; Animals; Antineoplastic Agents; Apoptosis; Benzamides; Blotting, Western; Cell Line, Tumor; Cell Proliferation; Diphenylamine; Electrophoretic Mobility Shift Assay; Enzyme Inhibitors; Female; Gene Expression; Humans; MAP Kinase Kinase Kinases; Melanoma; Mice; Mice, Nude; Mutation; Oligonucleotide Array Sequence Analysis; Phosphorylation; Proto-Oncogene Proteins B-raf; Signal Transduction; Xenograft Model Antitumor Assays | 2009 |
[18F]fluoromethyl-[1,2-2H4]-choline: a novel radiotracer for imaging choline metabolism in tumors by positron emission tomography.
Topics: Animals; Benzamides; Choline; Colonic Neoplasms; Deuterium; Diphenylamine; HCT116 Cells; Humans; Melanoma; Mice; Mice, Inbred BALB C; Mice, Nude; Oxidation-Reduction; Positron-Emission Tomography; Radiopharmaceuticals; Tissue Distribution; Transplantation, Heterologous | 2009 |
Selective BRAFV600E inhibition enhances T-cell recognition of melanoma without affecting lymphocyte function.
Topics: Antigens, Neoplasm; Benzamides; Butadienes; Cell Line, Tumor; Combined Modality Therapy; Diphenylamine; Epitopes, T-Lymphocyte; Extracellular Signal-Regulated MAP Kinases; gp100 Melanoma Antigen; Humans; Intramolecular Oxidoreductases; MAP Kinase Signaling System; MART-1 Antigen; Melanoma; Membrane Glycoproteins; Neoplasm Proteins; Nitriles; Oxidoreductases; Proto-Oncogene Proteins B-raf; T-Lymphocytes | 2010 |
The mitogen-activated protein kinase (MAPK) cascade controls phosphatase and tensin homolog (PTEN) expression through multiple mechanisms.
Topics: Animals; Benzamides; Diphenylamine; Disease Models, Animal; Enzyme Activation; Enzyme Inhibitors; Gene Expression Regulation, Enzymologic; Melanoma; Mice; Mitogen-Activated Protein Kinases; Phosphatidylinositol 3-Kinases; PTEN Phosphohydrolase; Signal Transduction | 2012 |
Specifically targeting ERK1 or ERK2 kills melanoma cells.
Topics: Agar; bcl-2-Associated X Protein; Benzamides; Caspases; Cell Death; Cell Line, Tumor; Cell Proliferation; Cell Survival; Diphenylamine; Drug Resistance, Neoplasm; Drug Screening Assays, Antitumor; Gene Knockdown Techniques; Gene Silencing; Humans; Indoles; Melanoma; Membrane Potential, Mitochondrial; Mitochondria; Mitogen-Activated Protein Kinase 1; Mitogen-Activated Protein Kinase 3; Neoplasm Proteins; Phosphorylation; Poly(ADP-ribose) Polymerases; Protease Inhibitors; RNA, Small Interfering; Sulfonamides; Tumor Stem Cell Assay; Vemurafenib | 2012 |
3'-deoxy-3'-[18F]fluorothymidine positron emission tomography is a sensitive method for imaging the response of BRAF-dependent tumors to MEK inhibition.
Topics: Animals; Benzamides; Blotting, Western; Dideoxynucleosides; Diphenylamine; Drug Resistance, Neoplasm; Female; G1 Phase; MAP Kinase Kinase 1; Melanoma; Mice; Mice, Nude; Positron-Emission Tomography; Proto-Oncogene Proteins B-raf; Radiopharmaceuticals; Tumor Cells, Cultured; Xenograft Model Antitumor Assays | 2007 |