diphenhydramine hydrochloride and Pregnancy

diphenhydramine hydrochloride has been researched along with Pregnancy in 42 studies

Research

Studies (42)

Timeframe	Studies, this research(%)	All Research%
pre-1990	17 (40.48)	18.7374
1990's	10 (23.81)	18.2507
2000's	9 (21.43)	29.6817
2010's	4 (9.52)	24.3611
2020's	2 (4.76)	2.80

Authors

Authors	Studies
Alameer, R; Alghanim, F; Alkattan, A; Alkhairat, M; Alkhalifah, A; Almaary, M; Alsalameen, E; Radwan, N	1
Feng, X; Tang, B; Wang, X; Wang, Y	1
Abdulla, S; Genton, B; Mazuguni, F; Mosha, D; Mrema, S	1
Chiang, YC; Ho, IK; Hsu, KY; Hung, TW; Liao, CW; Lo, WJ; Tao, PL; Ye, LC	1
Fujieda, Y; Kinoshita, M; Shirasaki, T; Soeda, F; Takahama, K	1
Mittal, R; Patil, PA; Torgal, SS	1
Hirakawa, E; Inoue, M; Shirasaki, T; Soeda, F; Takahama, K	1
Benaissa, F; Mahmoudian, M; Mehrpour, M; Nobakht, M; Siadatpour, Z; Ziai, SA	1
Au, WY; Tsang, SK	1
Ward, KE	1
Bozzo, P; Einarson, A; Erebara, A; Koren, G	1
Mulder, D; van Eeken, CJ	1
Ito, T; Watanabe, G; Watanabe, M; Yamamoto, M	1
Chasnoff, IJ; Diggs, G; Schnoll, SH	1
Sive, AA; Woods, DL	1
Cavalletti, E; Ceserani, R; Montaguti, P; Sala, F; Tognella, S	1
Bussi, R; Cavalletti, E; Ceserani, R; Montaguti, P; Tognella, S	1
Darj, E; Frenne, G; Rane, A; Wadelius, M	1
Polifka, JE; Shepard, TH	2
Brent, RL	2
Einarson, A; Koren, G	1
Martínez-Frías, ML; Rodríguez-Pinilla, E	1
Einarson, A; Koren, G; Lyszkiewicz, D	1
Debus, O; Gehrmann, J; Krasemann, T; Kurlemann, G	1
Li, A; Wang, Z; Yuan, S; Zhang, B; Zhao, Y	1
Su, CH; Tao, PL; Wu, YH; Yeh, GC	1
Goble, FC	1
Mallov, S	1
Chaney, MD; Craig, JP; Hill, RM; McCulley, LB; Tennyson, LM	1
Tamura, T	1
Granroth, G	1
Jesurun, CA; Levin, G; Slobodkin, D; Thompson, D	1
Bestetti, A; Giuliani, P; Melillo, G; Nunziata, A; Tonon, GC	1
Schenkel, B; Vorherr, H	1
Constantin, M; Pognat, JF; Streichenberger, G	1
Lehmann, H	1
Rydberg, U	1
Kopitar, Z	1
Kowa, Y	1
Nilsson, L	1

Reviews

4 review(s) available for diphenhydramine hydrochloride and Pregnancy

Article	Year
Opioid exposure during pregnancy and the risk of congenital malformation: a meta-analysis of cohort studies. BMC pregnancy and childbirth, 2022, May-11, Volume: 22, Issue:1 Topics: Analgesics, Opioid; Antitussive Agents; Cohort Studies; Female; Humans; Pregnancy; Pregnancy Trimester, First	2022
Treating the common cold during pregnancy. Canadian family physician Medecin de famille canadien, 2008, Volume: 54, Issue:5 Topics: Analgesics; Antitussive Agents; Common Cold; Expectorants; Female; Histamine H1 Antagonists; Humans; Nonprescription Drugs; Pregnancy; Pregnancy Complications, Infectious	2008
Sex as a factor in metabolism, toxicity, and efficacy of pharmacodynamic and chemotherapeutic agents. Advances in pharmacology and chemotherapy, 1975, Volume: 13 Topics: Anesthetics, Local; Animals; Anti-Infective Agents; Anti-Inflammatory Agents; Anticoagulants; Antineoplastic Agents; Antitussive Agents; Cardiac Glycosides; Cathartics; Central Nervous System; Depression, Chemical; Diuretics; Dogs; Female; Histamine H1 Antagonists; Humans; Hypoglycemic Agents; Male; Pharmaceutical Preparations; Pharmacology; Pregnancy; Psychotropic Drugs; Rabbits; Rats; Sex Factors; Stimulation, Chemical	1975
[The role of alcohol in therapy]. Lakartidningen, 1974, Apr-03, Volume: 71, Issue:14 Topics: Administration, Topical; Alcoholic Intoxication; Analgesics; Antitussive Agents; Aphrodisiacs; Body Temperature; Cardiovascular Diseases; Cough; Ethanol; Female; Fever; Humans; Hyperbilirubinemia, Hereditary; Hypnotics and Sedatives; Infant, Newborn; Methanol; Muscle Relaxants, Central; Obstetric Labor, Premature; Pain; Pregnancy	1974

Trials

1 trial(s) available for diphenhydramine hydrochloride and Pregnancy

Article	Year
The safety of dextromethorphan in pregnancy : results of a controlled study. Chest, 2001, Volume: 119, Issue:2 Topics: Adult; Antitussive Agents; Dextromethorphan; Female; Humans; Maternal-Fetal Exchange; Pregnancy; Pregnancy Outcome	2001

Other Studies

37 other study(ies) available for diphenhydramine hydrochloride and Pregnancy

Article	Year
Safety of English ivy (Hedera helix) leaf extract during pregnancy: retrospective cohort study. Daru : journal of Faculty of Pharmacy, Tehran University of Medical Sciences, 2021, Volume: 29, Issue:2 Topics: Adult; Antitussive Agents; Apgar Score; Birth Weight; Case-Control Studies; Female; Hedera; Humans; Infant, Newborn; Maternal Age; Plant Extracts; Plant Leaves; Pregnancy; Pregnancy Outcome; Retrospective Studies; Saudi Arabia	2021
Medication exposure during pregnancy: a pilot pharmacovigilance system using health and demographic surveillance platform. BMC pregnancy and childbirth, 2014, Sep-15, Volume: 14 Topics: Abortion, Spontaneous; Adolescent; Adult; Anti-Infective Agents; Antitussive Agents; Congenital Abnormalities; Dietary Supplements; Feasibility Studies; Female; Ferrous Compounds; Folic Acid; Gestational Age; Humans; Infant, Low Birth Weight; Live Birth; Middle Aged; Minerals; Pharmacovigilance; Population Surveillance; Pregnancy; Prospective Studies; Stillbirth; Tanzania; Vitamins; Young Adult	2014
Beneficial effects of co-treatment with dextromethorphan on prenatally methadone-exposed offspring. Journal of biomedical science, 2015, Mar-20, Volume: 22 Topics: Animals; Antitussive Agents; Dextromethorphan; Female; Male; Methadone; Morphine Dependence; Narcotics; Pregnancy; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley	2015
Centrally acting non-narcotic antitussives prevent hyperactivity in mice: Involvement of GIRK channels. Pharmacology, biochemistry, and behavior, 2016, Volume: 144 Topics: Animals; Antitussive Agents; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Hyperkinesis; Male; Mice; Pregnancy	2016
Screening of codeine, dextromethorphan & dextropropoxyphene for their genotoxicity in Swiss albino mice. The Indian journal of medical research, 2009, Volume: 129, Issue:6 Topics: Analgesics, Opioid; Animals; Antitussive Agents; Codeine; Comet Assay; Cyclophosphamide; Dextromethorphan; Dextropropoxyphene; DNA; DNA Damage; Erythrocytes; Female; Mice; Micronucleus Tests; Mutagens; Pregnancy	2009
Cloperastine rescues impairment of passive avoidance response in mice prenatally exposed to diethylstilbestrol. Environmental toxicology, 2014, Volume: 29, Issue:2 Topics: Animals; Antitussive Agents; Avoidance Learning; Brain-Derived Neurotrophic Factor; Diethylstilbestrol; Endocrine Disruptors; Female; G Protein-Coupled Inwardly-Rectifying Potassium Channels; Hippocampus; Learning Disabilities; Male; Mice; Neuroprotective Agents; Piperidines; Pregnancy; Prenatal Exposure Delayed Effects; Receptor, Serotonin, 5-HT1A	2014
Reduction of the prenatal hypoxic-ischemic brain edema with noscapine. Acta physiologica Hungarica, 2003, Volume: 90, Issue:4 Topics: Animals; Antitussive Agents; Basal Ganglia; Brain Edema; Cerebral Cortex; Disease Models, Animal; Female; Fetus; Hypoxia-Ischemia, Brain; Male; Noscapine; Pregnancy; Rats	2003
Cough mixture abuse in pregnancy, folate deficiency, and neural tube defects? American journal of hematology, 2005, Volume: 78, Issue:2 Topics: Adult; Antitussive Agents; Female; Folic Acid Deficiency; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Neural Tube Defects; Pregnancy; Pregnancy Complications; Substance-Related Disorders	2005
Can Robitussin DM be used to treat cough during pregnancy? Medicine and health, Rhode Island, 2005, Volume: 88, Issue:3 Topics: Abnormalities, Drug-Induced; Antitussive Agents; Cough; Dextromethorphan; Expectorants; Female; Guaifenesin; Humans; Maternal-Fetal Exchange; Nonprescription Drugs; Pregnancy; Pregnancy Complications	2005
The influence of xyloxemine hydrochloride, 2-[2-(DI-2,6-xylylmethoxy)ethoxy]-N,N-dimethylethylamine hydrochloride, on reproduction in laboratory animals. Archives internationales de pharmacodynamie et de therapie, 1967, Volume: 167, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Antitussive Agents; Female; Fertility; Fetus; Male; Pregnancy; Pregnancy, Animal; Rabbits; Rats; Reproduction; Testis	1967
Causes of chromosome anomalies suggested by cytogenetic epidemiology of induced abortions. Human genetics, 1982, Volume: 60, Issue:4 Topics: Abortion, Induced; Adolescent; Adult; Analgesics; Anti-Inflammatory Agents, Non-Steroidal; Antitussive Agents; Chromosome Aberrations; Chromosome Disorders; Embryo, Mammalian; Female; Humans; Maternal Age; Medical History Taking; Menstruation; Middle Aged; Ploidies; Pregnancy; Pregnancy Complications, Infectious; Respiratory Tract Infections; Trisomy; X-Rays	1982
Fetal alcohol effects and maternal cough syrup abuse. American journal of diseases of children (1960), 1981, Volume: 135, Issue:10 Topics: Antitussive Agents; Female; Fetal Alcohol Spectrum Disorders; Humans; Infant, Newborn; Pregnancy; Substance-Related Disorders	1981
Congenital goitre. South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde, 1980, Mar-29, Volume: 57, Issue:13 Topics: Antitussive Agents; Female; Goiter; Humans; Infant, Newborn; Infant, Newborn, Diseases; Male; Maternal-Fetal Exchange; Pregnancy	1980
General toxicology of the new antitussive moguisteine. Arzneimittel-Forschung, 1994, Volume: 44, Issue:11 Topics: Animals; Antitussive Agents; Carcinogens; Dogs; Female; Lethal Dose 50; Male; Mice; Mice, Inbred ICR; Mice, Inbred Strains; Mutagens; Pregnancy; Rabbits; Rats; Rats, Sprague-Dawley; Thiazoles; Thiazolidines	1994
Reproductive toxicology of the new antitussive moguisteine. Arzneimittel-Forschung, 1994, Volume: 44, Issue:12 Topics: Abnormalities, Drug-Induced; Animals; Antitussive Agents; Embryo, Mammalian; Female; Fertility; Growth; Labor, Obstetric; Male; Pregnancy; Prenatal Exposure Delayed Effects; Rabbits; Rats; Rats, Sprague-Dawley; Reproduction; Teratogens; Thiazoles; Thiazolidines; Weight Gain	1994
Induction of CYP2D6 in pregnancy. Clinical pharmacology and therapeutics, 1997, Volume: 62, Issue:4 Topics: Adult; Antitussive Agents; Aryl Hydrocarbon Hydroxylases; Cytochrome P-450 CYP2D6; Cytochrome P-450 CYP3A; Cytochrome P-450 Enzyme System; Dextromethorphan; Dextrorphan; DNA; Enzyme Induction; Female; Genotype; Humans; Oxidoreductases, N-Demethylating; Phenotype; Pregnancy	1997
The teratogenicity of N-methyl-D-aspartate (NMDA) receptor antagonists. Pediatric research, 1998, Volume: 44, Issue:3 Topics: Animals; Antitussive Agents; Chick Embryo; Dextromethorphan; Female; Humans; N-Methylaspartate; Pregnancy; Rabbits; Receptors, N-Methyl-D-Aspartate; Teratogens	1998
The teratogenicity of N-methyl-D-aspartate (NMDA) receptor antagonists. Pediatric research, 1998, Volume: 44, Issue:3 Topics: Animals; Antitussive Agents; Chick Embryo; Dextromethorphan; Female; Humans; Maternal-Fetal Exchange; N-Methylaspartate; Pregnancy; Receptors, N-Methyl-D-Aspartate; Teratogens	1998
Studies of the fetal effects of dextromethorphan in ovo. Teratology, 1999, Volume: 60, Issue:2 Topics: Antitussive Agents; Dextromethorphan; Female; Humans; Pregnancy; Teratogens	1999
Studies of the fetal effects of dextromethorphan in ovo. Teratology, 1999, Volume: 60, Issue:2 Topics: Animals; Antitussive Agents; Chick Embryo; Dextromethorphan; Dose-Response Relationship, Drug; Female; Humans; Models, Biological; Pregnancy; Rats; Teratogens	1999
Dextromethorphan. Extrapolation of findings from reproductive studies in animals to humans. Canadian family physician Medecin de famille canadien, 1999, Volume: 45 Topics: Abnormalities, Drug-Induced; Animals; Antitussive Agents; Chick Embryo; Dextromethorphan; Disease Models, Animal; Female; Humans; Pregnancy; Risk Assessment; Teratogens; Toxicity Tests	1999
Epidemiologic analysis of prenatal exposure to cough medicines containing dextromethorphan: no evidence of human teratogenicity. Teratology, 2001, Volume: 63, Issue:1 Topics: Antitussive Agents; Case-Control Studies; Congenital Abnormalities; Dextromethorphan; Female; Humans; Infant, Newborn; Male; Pregnancy; Prenatal Exposure Delayed Effects; Reference Values; Regression Analysis; Spain	2001
Dextromethorphan in pregnancy. Chest, 2001, Volume: 120, Issue:3 Topics: Antitussive Agents; Dextromethorphan; Female; Fetus; Humans; Pregnancy; Pregnancy Complications	2001
[Effects of processing on toxicity and pharmacological action of flos Genkwa]. Zhongguo Zhong yao za zhi = Zhongguo zhongyao zazhi = China journal of Chinese materia medica, 1998, Volume: 23, Issue:6 Topics: Animals; Antitussive Agents; Drugs, Chinese Herbal; Expectorants; Female; Hot Temperature; Magnoliopsida; Male; Mice; Muscle, Smooth; Plants, Medicinal; Pregnancy; Rabbits; Random Allocation; Rats; Rats, Wistar; Technology, Pharmaceutical; Uterine Contraction	1998
Co-administration of dextromethorphan during pregnancy and throughout lactation significantly decreases the adverse effects associated with chronic morphine administration in rat offspring. Life sciences, 2001, Oct-05, Volume: 69, Issue:20 Topics: Analgesics, Opioid; Animals; Antitussive Agents; Body Weight; Dextromethorphan; Drug Combinations; Drug Tolerance; Female; Hippocampus; Injections, Subcutaneous; Lactation; Longevity; Male; Morphine; Morphine Dependence; N-Methylaspartate; Pain Measurement; Pain Threshold; Pregnancy; Pregnancy, Animal; Prenatal Exposure Delayed Effects; Rats; Rats, Sprague-Dawley	2001
Drug interactions. Clinical obstetrics and gynecology, 1977, Volume: 20, Issue:2 Topics: Analgesics, Opioid; Anesthetics; Antacids; Anti-Bacterial Agents; Antiemetics; Antihypertensive Agents; Antitussive Agents; Appetite Depressants; Barbiturates; Bronchodilator Agents; Diuretics; Drug Interactions; Ethanol; Female; Histamine H1 Antagonists; Humans; Infant, Newborn; Iron; Magnesium Sulfate; Narcotic Antagonists; Pregnancy; Salicylates; Sulfonamides; Tranquilizing Agents; Vasodilator Agents; Vitamins	1977
Utilization of over-the-counter drugs during pregnancy. Clinical obstetrics and gynecology, 1977, Volume: 20, Issue:2 Topics: Analgesics; Antacids; Antitussive Agents; Coffee; Drug Utilization; Ethanol; Female; Fetus; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Infant, Newborn; Nasal Decongestants; Nonprescription Drugs; Pesticides; Pregnancy; Smoking; Solvents; Sweetening Agents; Tea	1977
[Use of local anesthetics containing vasoconstrictors in patients taking expectorants and antitussive agents]. Nihon Shika Ishikai zasshi, 1979, Volume: 32, Issue:4 Topics: Anesthesia, Dental; Anesthetics, Local; Antitussive Agents; Arrhythmias, Cardiac; Drug Synergism; Female; Humans; Pregnancy; Vasoconstrictor Agents	1979
Defects of the central nervous system in Finland: III. Disease and drugs in pregnancy. Early human development, 1978, Volume: 2, Issue:2 Topics: Abnormalities, Drug-Induced; Abnormalities, Multiple; Antitussive Agents; Central Nervous System; Congenital Abnormalities; Depression; Female; Fingers; Finland; Humans; Influenza, Human; Pre-Eclampsia; Pregnancy; Pregnancy Complications; Pregnancy Complications, Infectious; Pregnancy in Diabetics; Pregnancy Trimester, First	1978
Habituation to zipeprol hydrochloride during pregnancy. Journal of substance abuse treatment, 1992, Volume: 9, Issue:2 Topics: Adult; Antitussive Agents; Dose-Response Relationship, Drug; Female; Humans; Infant, Newborn; Neonatal Abstinence Syndrome; Neurologic Examination; Piperazines; Pregnancy; Risk Factors	1992
Safety and toxicological profile of the new antitussive levodropropizine. Arzneimittel-Forschung, 1988, Volume: 38, Issue:8 Topics: Abnormalities, Drug-Induced; Animals; Antitussive Agents; Body Weight; Dogs; Dose-Response Relationship, Drug; Drug Tolerance; Eating; Female; Fertility; Fetal Death; Guinea Pigs; Liver; Male; Mice; Mutagenicity Tests; Pregnancy; Propylene Glycols; Rabbits; Rats; Rats, Inbred Strains	1988
Non-prescription drugs during pregnancy: potential teratogenic and toxic effects upon embryo and fetus. The Journal of reproductive medicine, 1974, Volume: 12, Issue:1 Topics: Abnormalities, Drug-Induced; Analgesics; Antacids; Antitussive Agents; Cathartics; Expectorants; Female; Fetal Diseases; Fetus; Gestational Age; Histamine H1 Antagonists; Humans; Hypnotics and Sedatives; Nonprescription Drugs; Pregnancy; Pregnancy Complications; Self Medication; Sympathomimetics; Time Factors; Tranquilizing Agents	1974
Absorption, distribution and excretion of eprazinone in animals. Arzneimittel-Forschung, 1974, Volume: 24, Issue:11 Topics: Animals; Antitussive Agents; Autoradiography; Bile; Brain; Carbon Radioisotopes; Dogs; Female; Fetus; Half-Life; Kidney; Liver; Lung; Male; Mice; Piperazines; Pregnancy; Propiophenones; Rats	1974
[Reproduction-toxological studies with fominoben-HCl]. Arzneimittel-Forschung, 1974, Volume: 24, Issue:11 Topics: Anilides; Animals; Animals, Newborn; Antitussive Agents; Body Weight; Drug Evaluation, Preclinical; Embryo, Mammalian; Female; Fertility; Fetal Death; Methylamines; Mice; Morpholines; Pregnancy; Rabbits; Rats; Reproduction; Teratogens	1974
[Pharmacokinetics of 14 C-labelled fominoben in rats and pregnant mice]. Arzneimittel-Forschung, 1973, Volume: 23 Topics: Administration, Oral; Anilides; Animals; Antitussive Agents; Autoradiography; Bile; Carbon Isotopes; Feces; Female; Half-Life; Injections, Intravenous; Intestinal Absorption; Kinetics; Male; Maternal-Fetal Exchange; Methylamines; Mice; Morpholines; Pregnancy; Rats	1973
[Teratological study of a non-narcotic antitussive agent, Asverin]. Bollettino chimico farmaceutico, 1972, Volume: 111, Issue:1 Topics: Abnormalities, Drug-Induced; Animals; Antitussive Agents; Female; Fetus; Gestational Age; Piperidines; Pregnancy; Pregnancy, Animal; Rats	1972
Teratogenic studies on mice with an antiphlogistic substance, 5-(2-diethyl-aminoethyl)-3-phenyl-1,2,4-oxadiazole citrate (1). Arzneimittel-Forschung, 1967, Volume: 17, Issue:6 Topics: Abnormalities, Drug-Induced; Animals; Anti-Inflammatory Agents; Antitussive Agents; Embryonic and Fetal Development; Female; Fetus; Gestational Age; Mice; Oxadiazoles; Pregnancy; Ribs; Skeleton	1967