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diphenhydramine and Ventricular Fibrillation

diphenhydramine has been researched along with Ventricular Fibrillation in 4 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Ventricular Fibrillation: A potentially lethal cardiac arrhythmia that is characterized by uncoordinated extremely rapid firing of electrical impulses (400-600/min) in HEART VENTRICLES. Such asynchronous ventricular quivering or fibrillation prevents any effective cardiac output and results in unconsciousness (SYNCOPE). It is one of the major electrocardiographic patterns seen with CARDIAC ARREST.

Research Excerpts

ExcerptRelevanceReference
" It is suggested that the circulatory depression and the occurrence of ventricular arrhythmias following the administration of compound 48/80 result from activation of H1- and H2-receptors by elevated blood histamine levels due to release of the amine from tissues."3.68Circulatory depression and ventricular arrhythmias induced by compound 48/80 in anaesthetized rats. ( Dai, S, 1991)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19902 (50.00)18.7374
1990's1 (25.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (25.00)2.80

Authors

AuthorsStudies
Ryan, K1
Benz, P1
Zosel, A1
Farkas, A1
Theobald, J1
ALTMAN, KA1
Dai, S1
Lawson, JW1

Other Studies

4 other studies available for diphenhydramine and Ventricular Fibrillation

ArticleYear
QTc Prolongation in Poison Center Exposures to CredibleMeds List of Substances with "Known Risk of Torsades de Pointes".
    Cardiovascular toxicology, 2022, Volume: 22, Issue:9

    Topics: Amitriptyline; Arrhythmias, Cardiac; Diphenhydramine; Electrocardiography; Flecainide; Humans; Long

2022
VENTRICULAR FIBRILLATION.
    JAMA, 1964, Nov-23, Volume: 190

    Topics: Cardiovascular Diseases; Diphenhydramine; Drug Therapy; Electrocardiography; Humans; Isoproterenol;

1964
Circulatory depression and ventricular arrhythmias induced by compound 48/80 in anaesthetized rats.
    Agents and actions, 1991, Volume: 34, Issue:3-4

    Topics: Animals; Arrhythmias, Cardiac; Blood Pressure; Cardiovascular Physiological Phenomena; Cardiovascula

1991
Antiarrhythmic activity of some isoquinoline derivatives determined by a rapid screening procedure in the mouse.
    The Journal of pharmacology and experimental therapeutics, 1968, Volume: 160, Issue:1

    Topics: Animals; Anti-Arrhythmia Agents; Atropine; Chloroform; Diphenhydramine; Electrocardiography; Female;

1968