diphenhydramine has been researched along with Tachycardia in 11 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Tachycardia: Abnormally rapid heartbeat, usually with a HEART RATE above 100 beats per minute for adults. Tachycardia accompanied by disturbance in the cardiac depolarization (cardiac arrhythmia) is called tachyarrhythmia.
| Excerpt | Relevance | Reference |
|---|---|---|
| "A 28-year-old nulliparous patient at 41 weeks of gestation was treated for pruritus with intravenous diphenhydramine after epidural administration of fentanyl." | 7.85 | Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration. ( Abernathy, A; Alsina, L; Egerman, R; Greer, J, 2017) |
| "While seizures and sodium channel blockade are recognized complications of diphenhydramine toxicity, reported cases of status epilepticus from diphenhydramine overdose are rare." | 7.76 | Status epilepticus and wide-complex tachycardia secondary to diphenhydramine overdose. ( Duque, D; Hoffman, RS; Jang, DH; Manini, AF; Nelson, LS; Nestor, NB; Trueger, NS, 2010) |
| "Diphenhydramine poisoning is characterized most often by anticholinergic effects." | 7.68 | Massive diphenhydramine poisoning resulting in a wide-complex tachycardia: successful treatment with sodium bicarbonate. ( Clark, RF; Vance, MV, 1992) |
| "Atropine produces cardioacceleration in conscious dogs partly by reversing the pre-existing parasympathetic cardioinhibition and partly by inducing "excess tachycardia" (ET)." | 7.67 | Effects of antihistamines and local anesthetics on excess tachycardia in conscious dogs. ( Katona, PG; Rigel, DF, 1986) |
| " While in the emergency department, she manifested a wide-complex tachycardia in the setting of hypotension that required repeated administration of sodium bicarbonate to overcome the sodium channel blockade caused by diphenhydramine." | 4.02 | A Case of Massive Diphenhydramine and Naproxen Overdose. ( Backus, T; Furlano, E; Howland, MA; Mohan, S; Smith, SW; Su, MK, 2021) |
| "A 28-year-old nulliparous patient at 41 weeks of gestation was treated for pruritus with intravenous diphenhydramine after epidural administration of fentanyl." | 3.85 | Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration. ( Abernathy, A; Alsina, L; Egerman, R; Greer, J, 2017) |
| "A 13-month-old male who ingested 20 diphenhydramine (25 mg) tablets presented with seizures and ultimately progressed to status epilepticus and wide-complex tachycardia." | 3.77 | Survival after diphenhydramine ingestion with hemodialysis in a toddler. ( Hendrickson, RG; Horowitz, BZ; McKeown, NJ; West, PL, 2011) |
| "While seizures and sodium channel blockade are recognized complications of diphenhydramine toxicity, reported cases of status epilepticus from diphenhydramine overdose are rare." | 3.76 | Status epilepticus and wide-complex tachycardia secondary to diphenhydramine overdose. ( Duque, D; Hoffman, RS; Jang, DH; Manini, AF; Nelson, LS; Nestor, NB; Trueger, NS, 2010) |
| "Diphenhydramine poisoning is characterized most often by anticholinergic effects." | 3.68 | Massive diphenhydramine poisoning resulting in a wide-complex tachycardia: successful treatment with sodium bicarbonate. ( Clark, RF; Vance, MV, 1992) |
| "Atropine produces cardioacceleration in conscious dogs partly by reversing the pre-existing parasympathetic cardioinhibition and partly by inducing "excess tachycardia" (ET)." | 3.67 | Effects of antihistamines and local anesthetics on excess tachycardia in conscious dogs. ( Katona, PG; Rigel, DF, 1986) |
| " Complications of drug therapy included six-beat ventricular tachycardia and ventricular bigeminy (epinephrine) and exacerbated hypotension (diphenhydramine hydrochloride)." | 3.67 | Life-threatening hypotensive reactions to contrast media administration: comparison of pharmacologic and fluid therapy. ( Neff, CC; Pfister, RC; vanSonnenberg, E, 1987) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 3 (27.27) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 2 (18.18) | 29.6817 |
| 2010's | 4 (36.36) | 24.3611 |
| 2020's | 1 (9.09) | 2.80 |
| Authors | Studies |
|---|---|
| Mohan, S | 1 |
| Backus, T | 1 |
| Furlano, E | 1 |
| Howland, MA | 1 |
| Smith, SW | 1 |
| Su, MK | 1 |
| Abernathy, A | 1 |
| Alsina, L | 1 |
| Greer, J | 1 |
| Egerman, R | 1 |
| Mong, JS | 1 |
| Ooi, CK | 1 |
| Fridman, V | 1 |
| Galetta, SL | 1 |
| Pruitt, AA | 1 |
| Levine, JM | 1 |
| McKeown, NJ | 1 |
| West, PL | 1 |
| Hendrickson, RG | 1 |
| Horowitz, BZ | 1 |
| Jang, DH | 1 |
| Manini, AF | 1 |
| Trueger, NS | 1 |
| Duque, D | 1 |
| Nestor, NB | 1 |
| Nelson, LS | 1 |
| Hoffman, RS | 1 |
| Hannaway, PJ | 1 |
| Altorfer, R | 1 |
| Clark, RF | 1 |
| Vance, MV | 1 |
| Rigel, DF | 1 |
| Katona, PG | 1 |
| vanSonnenberg, E | 1 |
| Neff, CC | 1 |
| Pfister, RC | 1 |
11 other studies available for diphenhydramine and Tachycardia
| Article | Year |
|---|---|
A Case of Massive Diphenhydramine and Naproxen Overdose.
Topics: Diphenhydramine; Drug Overdose; Female; Humans; Naproxen; Sodium Bicarbonate; Tachycardia; Young Adu | 2021 |
Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration.
Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Cesarean Section; Diphenhydramine; Female; F | 2017 |
Transient Coagulopathy Due to Wasp Sting: A Case Report.
Topics: Adult; Anaphylaxis; Animals; Anti-Allergic Agents; Anti-Inflammatory Agents; Blood Coagulation Disor | 2017 |
MRI findings associated with acute liver failure.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Brain; Brain Edema; Coma; Diphenhydramine; Hepatic E | 2009 |
Survival after diphenhydramine ingestion with hemodialysis in a toddler.
Topics: Diphenhydramine; Humans; Hypnotics and Sedatives; Infant; Injections, Intramuscular; Male; Midazolam | 2011 |
Status epilepticus and wide-complex tachycardia secondary to diphenhydramine overdose.
Topics: Adult; Diphenhydramine; Drug Overdose; Electrocardiography; Female; Histamine H1 Antagonists; Humans | 2010 |
Emergency department treatment of anaphylaxis: is epinephrine always indicated?
Topics: Aged; Anaphylaxis; Anti-Inflammatory Agents, Non-Steroidal; Cimetidine; Contraindications; Diphenhyd | 2006 |
[Diphenhydramine poisoning (author's transl)].
Topics: Adolescent; Adult; Antidotes; Diphenhydramine; Female; Humans; Hypertension; Male; Psychoses, Substa | 1981 |
Massive diphenhydramine poisoning resulting in a wide-complex tachycardia: successful treatment with sodium bicarbonate.
Topics: Adolescent; Alcohol Drinking; Bicarbonates; Blood Gas Analysis; Charcoal; Diphenhydramine; Electroca | 1992 |
Effects of antihistamines and local anesthetics on excess tachycardia in conscious dogs.
Topics: Anesthetics, Local; Animals; Atropine; Chlorpheniramine; Diphenhydramine; Dogs; Dose-Response Relati | 1986 |
Life-threatening hypotensive reactions to contrast media administration: comparison of pharmacologic and fluid therapy.
Topics: Adolescent; Adult; Aged; Diatrizoate; Diphenhydramine; Drug Therapy, Combination; Epinephrine; Femal | 1987 |