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diphenhydramine and Stomach Ulcer

diphenhydramine has been researched along with Stomach Ulcer in 7 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Stomach Ulcer: Ulceration of the GASTRIC MUCOSA due to contact with GASTRIC JUICE. It is often associated with HELICOBACTER PYLORI infection or consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research Excerpts

ExcerptRelevanceReference
" This research first proposed that alterations of mast cell histamine release, gastric acid back-diffusion and mucosal microvascular permeability are important in modulating gastric ulcer and hemorrhage in Salmonella typhi-infected rats."3.72Role of histamine and acid back-diffusion in modulation of gastric microvascular permeability and hemorrhagic ulcers in Salmonella typhimurium-infected rats. ( Hung, CR; Wang, PS, 2004)
"Histamine is known to induce gastric ulcers in guinea pigs after intraperitoneal administration and duodenal ulcers after repeated intramuscular administrations."3.66Gastrointestinal ulceration in the guinea pig in response to dimaprit, histamine, and H1- and H2-blocking agents. ( Cho, CH; Pfeiffer, CJ, 1981)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19906 (85.71)18.7374
1990's0 (0.00)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Hung, CR1
Wang, PS1
Cho, CH1
Pfeiffer, CJ1
Serrano Sánchez, PA1
Filippos'iants, ST1
Cioli, V1
Silvestrini, B1
Dordoni, F1
Schapiro, H1
Smoligovets, PV1

Other Studies

7 other studies available for diphenhydramine and Stomach Ulcer

ArticleYear
Role of histamine and acid back-diffusion in modulation of gastric microvascular permeability and hemorrhagic ulcers in Salmonella typhimurium-infected rats.
    Life sciences, 2004, Mar-05, Volume: 74, Issue:16

    Topics: Amine Oxidase (Copper-Containing); Animals; Capillary Permeability; Diphenhydramine; Disease Models,

2004
Gastrointestinal ulceration in the guinea pig in response to dimaprit, histamine, and H1- and H2-blocking agents.
    Digestive diseases and sciences, 1981, Volume: 26, Issue:4

    Topics: Animals; Cimetidine; Dimaprit; Diphenhydramine; Duodenal Ulcer; Guinea Pigs; Histamine; Histamine H1

1981
[Gastrointestinal manifestations of systemic mastocytosis and its treatment with antagonists of H1 and H2 receptors. Experimental study].
    Revista espanola de las enfermedades del aparato digestivo, 1985, Volume: 67, Issue:2

    Topics: Animals; Cimetidine; Diarrhea; Diphenhydramine; Duodenal Ulcer; Exocytosis; Female; Male; Rats; Stom

1985
[Effect of polymyxin M on the content of histamine and serotonin in the blood and tissue of rats].
    Antibiotiki, 1966, Volume: 11, Issue:11

    Topics: Animals; Diphenhydramine; Ear; Edema; Hemorrhage; Histamine; Histamine H1 Antagonists; Histamine Rel

1966
Evaluation of the potential of gastric ulceration after administration of certain drugs.
    Experimental and molecular pathology, 1967, Volume: 6, Issue:1

    Topics: Amines; Aminopyrine; Animals; Ascorbic Acid; Aspirin; Chlorpromazine; Cortisone; Desoxycorticosteron

1967
The action of reserpine on gastric secretion.
    Archives of surgery (Chicago, Ill. : 1960), 1967, Volume: 95, Issue:1

    Topics: Animals; Atropine; Central Nervous System; Diphenhydramine; Dogs; Duodenal Ulcer; Fasting; Gastric J

1967
[Dimedrol in the complex therapy of patients with peptic ulcer and chronic gastritis].
    Vrachebnoe delo, 1966, Volume: 3

    Topics: Adult; Aged; Chronic Disease; Diet Therapy; Digestion; Diphenhydramine; Duodenal Ulcer; Female; Gast

1966