diphenhydramine has been researched along with Stevens-Johnson Syndrome in 9 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Stevens-Johnson Syndrome: Rare cutaneous eruption characterized by extensive KERATINOCYTE apoptosis resulting in skin detachment with mucosal involvement. It is often provoked by the use of drugs (e.g., antibiotics and anticonvulsants) or associated with PNEUMONIA, MYCOPLASMA. It is considered a continuum of Toxic Epidermal Necrolysis.
Excerpt | Relevance | Reference |
---|---|---|
"We selected adverse drug reaction (ADR) reports on H1-antihistamines in children (0-16 years) up to June 2014 from VigiBase." | 1.46 | Safety profile of H1-antihistamines in pediatrics: an analysis based on data from VigiBase. ( Biagi, C; Calamelli, E; Cipriani, F; Donati, M; Melis, M; Monaco, L; Motola, D; Ricci, G; Vaccheri, A, 2017) |
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 5 (55.56) | 18.7374 |
1990's | 2 (22.22) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 2 (22.22) | 24.3611 |
2020's | 0 (0.00) | 2.80 |
Authors | Studies |
---|---|
Motola, D | 1 |
Donati, M | 1 |
Biagi, C | 1 |
Calamelli, E | 1 |
Cipriani, F | 1 |
Melis, M | 1 |
Monaco, L | 1 |
Vaccheri, A | 1 |
Ricci, G | 1 |
Minor, DR | 1 |
Rodvien, R | 1 |
Kashani-Sabet, M | 1 |
PINDBORG, JJ | 1 |
PINDBORG, S | 1 |
Yusin, JS | 1 |
Crawford, WW | 1 |
Klaustermeyer, WB | 1 |
Ward, B | 1 |
McCulley, JP | 1 |
Segal, RJ | 1 |
Soskin, IaM | 1 |
Kruglikova, LI | 1 |
Epishin, AV | 1 |
Likhatskaia, VA | 1 |
Furtel', PA | 1 |
Kiĭko, FIu | 1 |
Vanat, IM | 1 |
Timperman, J | 1 |
Verbauwhede, W | 1 |
9 other studies available for diphenhydramine and Stevens-Johnson Syndrome
Article | Year |
---|---|
Safety profile of H1-antihistamines in pediatrics: an analysis based on data from VigiBase.
Topics: Adolescent; Adverse Drug Reaction Reporting Systems; Cetirizine; Child; Child Mortality; Child, Pres | 2017 |
Successful desensitization in a case of Stevens-Johnson syndrome due to vemurafenib.
Topics: Desensitization, Immunologic; Dexamethasone; Diphenhydramine; Female; Humans; Indoles; Middle Aged; | 2012 |
[Erythema multiforme exsudativum (Stevens-Johnson syndrome) with special consideration on oral manifestations and benadryl therapy].
Topics: Diphenhydramine; Erythema Multiforme; Humans; Stevens-Johnson Syndrome | 1953 |
Facial edema, oral ulcers, and a cutaneous eruption following a dental procedure utilizing diflunisal and mepivacaine.
Topics: Anesthetics, Local; Anti-Inflammatory Agents, Non-Steroidal; Dexamethasone; Diflunisal; Diphenhydram | 1999 |
Dermatologic reaction in Stevens-Johnson syndrome after ophthalmic anesthesia with proparacaine hydrochloride.
Topics: Anesthetics, Local; Conjunctivitis; Diphenhydramine; Female; Furosemide; Humans; Middle Aged; Ophtha | 1978 |
[Acute epidermal necrolysis (Lyell's syndrome) after diagnostic curettage of the uterus].
Topics: Acute Disease; Aged; Dilatation and Curettage; Diphenhydramine; Drug Hypersensitivity; Female; Human | 1978 |
[Recurrent Lyell's syndrome with secondary thrombocytopenia].
Topics: Adjuvants, Immunologic; Aminopyrine; Diphenhydramine; Dipyrone; Female; Humans; Middle Aged; Povidon | 1991 |
[Case of cure of Lyell's syndrome].
Topics: Anti-Infective Agents, Local; Calcium Chloride; Diphenhydramine; Drug Therapy, Combination; Female; | 1974 |
Toxic epidermal necrolysis (Lyell syndrome) and its medico-legal implications.
Topics: Child, Preschool; Diphenhydramine; Female; Forensic Medicine; Humans; Phenylbutazone; Phenylephrine; | 1972 |