diphenhydramine has been researched along with Serotonin Syndrome in 3 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Serotonin Syndrome: An adverse drug interaction characterized by altered mental status, autonomic dysfunction, and neuromuscular abnormalities. It is most frequently caused by use of both serotonin reuptake inhibitors and monoamine oxidase inhibitors, leading to excess serotonin availability in the CNS at the serotonin 1A receptor.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Serotonin syndrome is an under-reported and under-recognised condition that occurs on administration of selective serotonin re-uptake inhibitors alone, or in combination with other medication known to increase levels of 5-hydroxytryptamine." | 1.34 | Serotonin syndrome. ( Evans, CE; Sebastian, J, 2007) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 2 (66.67) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Tanaka, T | 1 |
| Takasu, A | 1 |
| Yoshino, A | 1 |
| Terazumi, K | 1 |
| Ide, M | 1 |
| Nomura, S | 1 |
| Sakamoto, T | 1 |
| Sanaei-Zadeh, H | 1 |
| Evans, CE | 1 |
| Sebastian, J | 1 |
3 other studies available for diphenhydramine and Serotonin Syndrome
| Article | Year |
|---|---|
Diphenhydramine overdose mimicking serotonin syndrome.
Topics: Adolescent; Diphenhydramine; Drug Overdose; Female; Humans; Selective Serotonin Reuptake Inhibitors; | 2011 |
Diphenhydramine overdose and serotonin syndrome.
Topics: Diphenhydramine; Female; Humans; Selective Serotonin Reuptake Inhibitors; Serotonin Syndrome | 2012 |
Serotonin syndrome.
Topics: Adult; Diphenhydramine; Drug Overdose; Female; Glasgow Coma Scale; Humans; Paroxetine; Serotonin Syn | 2007 |