Page last updated: 2024-10-26

diphenhydramine and Schizophrenia

diphenhydramine has been researched along with Schizophrenia in 13 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Schizophrenia: A severe emotional disorder of psychotic depth characteristically marked by a retreat from reality with delusion formation, HALLUCINATIONS, emotional disharmony, and regressive behavior.

Research Excerpts

ExcerptRelevanceReference
"A chronic schizophrenic patient received 30 mg fluphenazine hydrochloride (Prolixin) PO and developed priapism."7.67Priapism resulting from fluphenazine hydrochloride treatment reversed by diphenhydramine. ( Fishbain, DA, 1985)
"A chronic schizophrenic patient received 30 mg fluphenazine hydrochloride (Prolixin) PO and developed priapism."3.67Priapism resulting from fluphenazine hydrochloride treatment reversed by diphenhydramine. ( Fishbain, DA, 1985)
"Amantadine hydrochloride is an antiviral medication used as therapy for parkinsonism and as a cognitive enhancer."1.35Cardiotoxicity after massive amantadine overdose. ( Kazzi, Z; Morgan, B; Patel, M; Schwartz, M, 2008)

Research

Studies (13)

TimeframeStudies, this research(%)All Research%
pre-199010 (76.92)18.7374
1990's2 (15.38)18.2507
2000's1 (7.69)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Schwartz, M1
Patel, M1
Kazzi, Z1
Morgan, B1
SHPAK, VM1
HANKOFF, LD1
GUNDLACH, RH1
PALEY, HM1
RUDORFER, L1
Smirnov, VK1
Witschy, JK1
Redmond, FC1
Christensen, RC1
de Nesnera, AP1
Fishbain, DA1
Wallace, MR1
Allen, E1
Okuma, T1
Kawahara, R1
Umezawa, Y1
Kashiwagi, T1
Guz, I1
Segre, CD1
Ribas, JC1
Nigro, SA1
Yelin, G1
Gralnick, A1

Other Studies

13 other studies available for diphenhydramine and Schizophrenia

ArticleYear
Cardiotoxicity after massive amantadine overdose.
    Journal of medical toxicology : official journal of the American College of Medical Toxicology, 2008, Volume: 4, Issue:3

    Topics: Adult; Amantadine; Antiparkinson Agents; Arrhythmias, Cardiac; Blood Gas Analysis; Blood Pressure; C

2008
[Clinical results of dimedrol therapy of schizophrenia; preliminary communication].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1954, Volume: 54, Issue:9

    Topics: Communication; Diphenhydramine; Humans; Schizophrenia

1954
DIPHENHYDRAMINE AS AN ANTIDEPRESSANT: A NEGATIVE FINDING.
    Diseases of the nervous system, 1964, Volume: 25

    Topics: Antidepressive Agents; Biomedical Research; Bipolar Disorder; Depressive Disorder, Major; Diphenhydr

1964
[Status of microhemodynamics and features of capillary permeability in schizophrenia].
    Zhurnal nevropatologii i psikhiatrii imeni S.S. Korsakova (Moscow, Russia : 1952), 1982, Volume: 82, Issue:5

    Topics: Adult; Capillary Permeability; Diphenhydramine; Ethinyl Estradiol; Female; Haloperidol; Histamine H1

1982
Extrapyramidal reaction to fluphenazine potentiated by thyrotoxicosis.
    The American journal of psychiatry, 1981, Volume: 138, Issue:2

    Topics: Basal Ganglia Diseases; Diphenhydramine; Drug Therapy, Combination; Fluphenazine; Humans; Hyperthyro

1981
Misdiagnosis of anticholinergic delerium as schizophrenic psychosis.
    The American journal of emergency medicine, 1995, Volume: 13, Issue:1

    Topics: Adult; Delirium; Diagnostic Errors; Diphenhydramine; Drug Overdose; Humans; Male; Schizophrenia

1995
Diphenhydramine dependence: a need for awareness.
    The Journal of clinical psychiatry, 1996, Volume: 57, Issue:3

    Topics: Adult; Antipsychotic Agents; Delayed-Action Preparations; Diphenhydramine; Fluphenazine; Humans; Mal

1996
Priapism resulting from fluphenazine hydrochloride treatment reversed by diphenhydramine.
    Annals of emergency medicine, 1985, Volume: 14, Issue:6

    Topics: Adult; Diphenhydramine; Fluphenazine; Humans; Injections, Intravenous; Male; Priapism; Schizophrenia

1985
Recovery after massive overdose of diphenhydramine and methaqualone.
    Lancet (London, England), 1968, Dec-07, Volume: 2, Issue:7580

    Topics: Adult; Diphenhydramine; Electroencephalography; Female; Humans; Methaqualone; Positive-Pressure Resp

1968
An electroencephalographic study on the tolerance of psychiatric and neurologic patients to the hypnotic effect of diphenhydramine.
    Folia psychiatrica et neurologica japonica, 1973, Volume: 27, Issue:2

    Topics: Adolescent; Adult; Bipolar Disorder; Diphenhydramine; Drug Tolerance; Electroencephalography; Epilep

1973
[Use of the combination methaqualone-diphenyhydramine in ambulatory patients].
    Hospital (Rio de Janeiro, Brazil), 1969, Volume: 76, Issue:6

    Topics: Adolescent; Adult; Alcoholism; Ambulatory Care; Anxiety; Diphenhydramine; Female; Humans; Male; Meth

1969
Toxic psychosis due to diphenhydramine hydrochloride.
    JAMA, 1968, Jan-22, Volume: 203, Issue:4

    Topics: Adolescent; Diphenhydramine; Female; Humans; Mental Disorders; Parasympathetic Nervous System; Psych

1968
Near fatality in phenothiazine therapy (case report).
    Diseases of the nervous system, 1968, Volume: 29, Issue:10

    Topics: Adult; Death, Sudden; Diphenhydramine; Female; Heart Arrest; Heart Massage; Humans; Phenothiazines;

1968