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diphenhydramine and Rhinitis, Allergic, Seasonal

diphenhydramine has been researched along with Rhinitis, Allergic, Seasonal in 33 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Rhinitis, Allergic, Seasonal: Allergic rhinitis that occurs at the same time every year. It is characterized by acute CONJUNCTIVITIS with lacrimation and ITCHING, and regarded as an allergic condition triggered by specific ALLERGENS.

Research Excerpts

ExcerptRelevanceReference
"Ninety-one hay fever patients received either 0."6.65A double-blind comparison of oxatomide (R 35 443) and diphenhydramine in the treatment of hay fever. ( Cordier, R; De Proost, W; van der Bijl, WJ; van Dishoeck, EA; Vannieuwenhuyse, E, 1980)
"Ninety-one hay fever patients received either 0."2.65A double-blind comparison of oxatomide (R 35 443) and diphenhydramine in the treatment of hay fever. ( Cordier, R; De Proost, W; van der Bijl, WJ; van Dishoeck, EA; Vannieuwenhuyse, E, 1980)
"Effective treatment of allergic rhinitis, therefore, consists of: (1) changing the patient's environment in order to remove the offending allergens, (2) removing the patient from his environment, (3) altering the patient's response to environmental allergens by means of hyposensitization injections, (4) suppressing the allergic reaction with drugs, and (5) eliminating bacterial infection."1.24THE TREATMENT OF ALLERGIC RHINITIS. ( FREEDMAN, SO, 1964)

Research

Studies (33)

TimeframeStudies, this research(%)All Research%
pre-199021 (63.64)18.7374
1990's4 (12.12)18.2507
2000's7 (21.21)29.6817
2010's1 (3.03)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
BERNSTEIN, TB1
ROSE, JM1
FEINBERG, SM1
SCHOEMPERLEN, CB1
BARNETT, SE2
GOSS, SB2
BARBAS, FM1
HARLEY, D1
KOELSCHE, GA1
PRICKMAN, LE1
CARRYER, HM1
JENKINS, DE1
SCHREIBER, EO1
SHELDON, JM1
Sansgiry, SS1
Shringarpure, GS1
ROWE, RG1
YOUNG, MJ1
ROSSIER, M1
FREEDMAN, SO1
PORSIO, A1
BORGIA, M1
Wilken, JA1
Kane, RL1
Ellis, AK1
Rafeiro, E1
Briscoe, MP1
Sullivan, CL1
Day, JH1
Raphael, GD1
Angello, JT1
Wu, MM1
Druce, HM1
Blaiss, MS1
Weiner, M1
van der Bijl, WJ1
Cordier, R1
van Dishoeck, EA1
De Proost, W1
Vannieuwenhuyse, E2
Naclerio, RM2
Vuurman, EF2
van Veggel, LM2
Uiterwijk, MM1
Leutner, D1
O'Hanlon, JF2
Sanders, RL1
Muntjewerff, ND1
Weiler, JM1
Bloomfield, JR1
Woodworth, GG1
Grant, AR1
Layton, TA1
Brown, TL1
McKenzie, DR1
Baker, TW1
Watson, GS1
Bender, BG1
McCormick, DR1
Milgrom, H1
de Beule, R1
Callier, J1
Verstraete, W1
Degreef, F1
Gregoire, M1
Robience, Y1
Stevens, W1
Libert, P1
Bespal'ko, NN1
Baklanova, TI1
Zolkina, TD1
Roshal', NI1
Nadmochiĭ, AS1
Majchel, AM1
Proud, D1
Kagey-Sobotka, A1
Witek, TJ1
Lichtenstein, LM1
von Maur, K1
Krasnowska, M1
Liebhart, E1
Wrzyszcz, M1
Małolepszy, J1
Wohlzogen, FX1
Wodniansky, P1
Knothe, J1
Baerthold, W1
Aschoff, E1
Shereff, RH1
Harwell, W1
Lieberman, P1
Rosenberg, EW1
Robinson, H1
Smith, RE1
Casanova-Roig, R1
Wells, DE1

Trials

14 trials available for diphenhydramine and Rhinitis, Allergic, Seasonal

ArticleYear
A comparison of the effect of diphenhydramine and desloratadine on vigilance and cognitive function during treatment of ragweed-induced allergic rhinitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2003, Volume: 91, Issue:4

    Topics: Allergens; Ambrosia; Anti-Allergic Agents; Arousal; Cognition; Diphenhydramine; Double-Blind Method;

2003
Efficacy of diphenhydramine vs desloratadine and placebo in patients with moderate-to-severe seasonal allergic rhinitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 96, Issue:4

    Topics: Adolescent; Adult; Aged; Anti-Allergic Agents; Child; Diphenhydramine; Double-Blind Method; Female;

2006
A double-blind comparison of oxatomide (R 35 443) and diphenhydramine in the treatment of hay fever.
    The Laryngoscope, 1980, Volume: 90, Issue:1

    Topics: Adolescent; Adult; Child; Clinical Trials as Topic; Diphenhydramine; Double-Blind Method; Fatigue; F

1980
The effect of antihistamines on the immediate allergic response: a comparative review.
    Otolaryngology--head and neck surgery : official journal of American Academy of Otolaryngology-Head and Neck Surgery, 1993, Volume: 108, Issue:6

    Topics: Capillary Permeability; Cetirizine; Cyproheptadine; Diphenhydramine; Double-Blind Method; Histamine

1993
Seasonal allergic rhinitis and antihistamine effects on children's learning.
    Annals of allergy, 1993, Volume: 71, Issue:2

    Topics: Child; Cognition; Diphenhydramine; Female; Humans; Hypersensitivity, Immediate; Learning; Loratadine

1993
Effects of semprex-D and diphenhydramine on learning in young adults with seasonal allergic rhinitis.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 1996, Volume: 76, Issue:3

    Topics: Adolescent; Adult; Diphenhydramine; Double-Blind Method; Drug Combinations; Ephedrine; Female; Hista

1996
Effects of fexofenadine, diphenhydramine, and alcohol on driving performance. A randomized, placebo-controlled trial in the Iowa driving simulator.
    Annals of internal medicine, 2000, Mar-07, Volume: 132, Issue:5

    Topics: Adult; Automobile Driving; Cross-Over Studies; Diphenhydramine; Double-Blind Method; Ethanol; Female

2000
Children's school performance is not impaired by short-term administration of diphenhydramine or loratadine.
    The Journal of pediatrics, 2001, Volume: 138, Issue:5

    Topics: Child; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Learning; Loratadine; Male; Rhinit

2001
Double-blind placebo-controlled clinical evaluation of oxatimide (R 35443). A novel potent anti-allergic drug in the treatment of hay fever.
    Acta allergologica, 1977, Volume: 32, Issue:4

    Topics: Administration, Oral; Adolescent; Adult; Aged; Child; Child, Preschool; Clinical Trials as Topic; Di

1977
Evaluation of a bedtime dose of a combination antihistamine/analgesic/decongestant product on antigen challenge the next morning.
    The Laryngoscope, 1992, Volume: 102, Issue:3

    Topics: Acetaminophen; Adult; Antigens; Diphenhydramine; Double-Blind Method; Drug Therapy, Combination; Eph

1992
Antihistamine selection in patients with allergic rhinitis.
    Annals of allergy, 1985, Volume: 55, Issue:3

    Topics: Chlorpheniramine; Clinical Trials as Topic; Diphenhydramine; Histamine H1 Antagonists; Humans; Hydro

1985
[Effect of H1 and H2 receptor antagonists on the skin and bronchial reactivity in patients with hay fever].
    Pneumonologia polska, 1986, Volume: 54, Issue:10

    Topics: Adult; Bronchial Provocation Tests; Cimetidine; Clinical Trials as Topic; Diphenhydramine; Drug Ther

1986
[Comparative trial of anti-allergy preparations in subjects allergic to pollen].
    Internationale Zeitschrift fur klinische Pharmakologie, Therapie, und Toxikologie. International journal of clinical pharmacology, therapy, and toxicology, 1969, Volume: 2, Issue:4

    Topics: Analysis of Variance; Clinical Trials as Topic; Diphenhydramine; Female; Histamine Release; Humans;

1969
[Treatment results with dioxopromethazine nose drops].
    Die Pharmazie, 1970, Feb-02, Volume: 25, Issue:2

    Topics: Clinical Trials as Topic; Diphenhydramine; Histocytochemistry; Humans; Imidazoles; Naphazoline; Naph

1970

Other Studies

19 other studies available for diphenhydramine and Rhinitis, Allergic, Seasonal

ArticleYear
New antihistaminic drugs (benadryl, pyribenzamine and neoantergan) in hay fever and other allergic conditions.
    The Illinois medical journal, 1947, Volume: 92, Issue:2

    Topics: Anaphylaxis; Anti-Allergic Agents; Diphenhydramine; Histamine; Histamine Antagonists; Hypersensitivi

1947
Benadryl in treatment of mucosal respiratory syndrome.
    Canadian Medical Association journal, 1947, Volume: 56, Issue:1

    Topics: Amino Acids; Diphenhydramine; Drug Combinations; Ethers; Humans; Mucous Membrane; Respiratory System

1947
Further observations on the use of benadryl in hay fever, asthma, vasomotor rhinitis, and in mixed allergic groups.
    Eye, ear, nose & throat monthly, 1947, Volume: 26, Issue:4

    Topics: Amino Acids; Anaphylaxis; Asthma; Diphenhydramine; Drug Combinations; Ethers; Humans; Hypersensitivi

1947
Ahh-choo! How to sneeze at allergies.
    Consumer reports, 2010, Volume: 75, Issue:5

    Topics: Adrenal Cortex Hormones; Cetirizine; Diphenhydramine; Health Behavior; Health Care Surveys; Histamin

2010
Benadryl in hay fever, asthma, and vasomotor rhinitis.
    Journal - Michigan State Medical Society, 1946, Volume: 45

    Topics: Anaphylaxis; Asthma; Diphenhydramine; Humans; Hypersensitivity; Immune System Diseases; Rhinitis; Rh

1946
Benadryl in hay-fever; a note on its action.
    Lancet (London, England), 1946, Aug-03, Volume: 2, Issue:6414

    Topics: Diphenhydramine; Humans; Hyperthermia, Induced; Rhinitis, Allergic, Seasonal

1946
The symptomatic treatment of bronchial asthma and hay fever with benadryl.
    Proceedings of the staff meetings. Mayo Clinic, 1945, Nov-14, Volume: 20

    Topics: Anaphylaxis; Asthma; Diphenhydramine; Humans; Hypersensitivity; Hyperthermia, Induced; Immune System

1945
Benadryl (beta-dimethylaminoethyl benzhydryl ether hydrochloride) in the treatment of hay fever and asthma.
    University Hospital bulletin, 1946, Volume: 12

    Topics: Asthma; Diphenhydramine; Ether; Ethers; Rhinitis, Allergic, Seasonal; Salts

1946
Springtime confusion: are consumers getting the right information on how to treat seasonal allergies?
    The Journal of allergy and clinical immunology, 2003, Volume: 112, Issue:3

    Topics: Advertising; Diphenhydramine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedating; Huma

2003
CLINICAL EVALUATION OF A NEW ANTIHISTAMINE, MEBROPHENHYDRAMINE.
    Applied therapeutics, 1963, Volume: 5

    Topics: Asthma; Dermatitis; Diphenhydramine; Histamine H1 Antagonists; Humans; Insect Bites and Stings; Phar

1963
[INDICATIONS, THERAPEUTIC EFFICACY AND TOLERANCE OF AN ANTIHISTAMINIC SYNERGISM (DIVAHISTINE)].
    Therapeutische Umschau. Revue therapeutique, 1963, Volume: 20

    Topics: Ascorbic Acid; Caffeine; Common Cold; Diphenhydramine; Humans; Immune Tolerance; Nasal Decongestants

1963
THE TREATMENT OF ALLERGIC RHINITIS.
    Canadian Medical Association journal, 1964, Sep-12, Volume: 91

    Topics: Allergens; Desensitization, Immunologic; Diphenhydramine; Environment; Humans; Hypersensitivity; Imm

1964
[ON THE THERAPEUTIC POSSIBILITIES OF A NEW DRUG ASSOCIATION WITH ANTIALLERGIC AND ANTIEXUDATIVE ACTIVITY].
    La Clinica terapeutica, 1964, Nov-15, Volume: 31

    Topics: Aminocaproates; Aminocaproic Acid; Anti-Allergic Agents; Diphenhydramine; Drug Hypersensitivity; Dru

1964
Diphenhydramine vs desloratadine comparisons must consider risk-benefit ratio.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2006, Volume: 97, Issue:1

    Topics: Cognition Disorders; Diphenhydramine; Histamine H1 Antagonists; Histamine H1 Antagonists, Non-Sedati

2006
Sedation and antihistaminics.
    Arzneimittel-Forschung, 1982, Volume: 32, Issue:9a

    Topics: Benzhydryl Compounds; Diphenhydramine; Electroencephalography; Electromyography; Electrooculography;

1982
Newer antihistamines.
    The Medical letter on drugs and therapeutics, 2001, Apr-30, Volume: 43, Issue:1103

    Topics: Administration, Oral; Anti-Allergic Agents; Cetirizine; Chlorpheniramine; Conscious Sedation; Diphen

2001
[Use of physical factors in the complex treatment of rhinosinusitis in children].
    Pediatriia, 1975, Issue:4

    Topics: Calcium Chloride; Child; Child, Preschool; Diphenhydramine; Humans; Iontophoresis; Maxillary Sinus;

1975
Effect of beta adrenergic stimulation and blockade on immediate hypersensitivity skin test reactions.
    The Journal of allergy and clinical immunology, 1973, Volume: 52, Issue:6

    Topics: Asthma; Diphenhydramine; Humans; Hypersensitivity, Immediate; Iontophoresis; Isoproterenol; Proprano

1973
The effect of antihistamines on nasal smear eosinophiles in patients with allergic rhinitis.
    Annals of allergy, 1968, Volume: 26, Issue:2

    Topics: Adolescent; Adult; Child; Child, Preschool; Diphenhydramine; Eosinophils; Female; Humans; Male; Midd

1968