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diphenhydramine and Pulmonary Hypertension

diphenhydramine has been researched along with Pulmonary Hypertension in 7 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Research Excerpts

ExcerptRelevanceReference
"Ethchlorvynol (10 mg/kg) causes transient pulmonary hypertension and an increased permeability pulmonary edema in sheep."7.66Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema. ( Fairman, RP; Falls, RK; Glauser, FL; Millen, JE, 1982)
" During pentobarbital anesthesia, 2 pulmonary hemodynamic studies were conducted on each dog with a sequence of baseline, hypoxia with FlO2 = 10%, hyperoxia with FlO2 = 100%, a second baseline, treatment with either diphenhydramine (D) or cimetidine (C), and another hypoxia."3.68Postadulticide pulmonary hypertension of canine heartworm disease: successful treatment with oxygen and failure of antihistamines. ( Rawlings, CA; Tackett, RL, 1990)
"Ethchlorvynol (10 mg/kg) causes transient pulmonary hypertension and an increased permeability pulmonary edema in sheep."3.66Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema. ( Fairman, RP; Falls, RK; Glauser, FL; Millen, JE, 1982)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19904 (57.14)18.7374
1990's2 (28.57)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sundararaghavan, S1
Suarez, WA1
Glauser, FL2
Fairman, RP2
Millen, JE1
Falls, RK1
Leeper-Woodford, SK1
Carey, D1
Byrne, K1
Walsh, C1
Fisher, B1
Sugerman, HJ1
Fowler, AA1
Daoud, FS1
Reeves, JT1
Kelly, DB1
Rawlings, CA1
Tackett, RL1
Sessler, CN1
Bierman, M1
Susmano, A1
Carleton, RA1

Other Studies

7 other studies available for diphenhydramine and Pulmonary Hypertension

ArticleYear
Oral benadryl and central venous catheter abuse-a potentially "lethal combination".
    Pediatric emergency care, 2004, Volume: 20, Issue:9

    Topics: Adolescent; Catheterization, Central Venous; Diphenhydramine; Female; Humans; Hypertension, Pulmonar

2004
Indomethacin blunts ethchlorvynol-induced pulmonary hypertension but not pulmonary edema.
    Journal of applied physiology: respiratory, environmental and exercise physiology, 1982, Volume: 53, Issue:3

    Topics: Animals; Blood Pressure; Diphenhydramine; Ethchlorvynol; Hypertension, Pulmonary; Indomethacin; Phen

1982
Histamine receptor antagonists, cyclooxygenase blockade, and tumor necrosis factor during acute septic insult.
    Shock (Augusta, Ga.), 1998, Volume: 9, Issue:2

    Topics: Animals; Bacteremia; Blood Pressure; Cardiac Output; Cimetidine; Cyclooxygenase Inhibitors; Diphenhy

1998
Isoproterenol as a potential pulmonary vasodilator in primary pulmonary hypertension.
    The American journal of cardiology, 1978, Volume: 42, Issue:5

    Topics: Administration, Oral; Adolescent; Adult; Azathioprine; Cardiac Catheterization; Cardiac Output; Diph

1978
Postadulticide pulmonary hypertension of canine heartworm disease: successful treatment with oxygen and failure of antihistamines.
    American journal of veterinary research, 1990, Volume: 51, Issue:10

    Topics: Animals; Arsenamide; Blood Pressure; Cimetidine; Diphenhydramine; Dirofilariasis; Dog Diseases; Dogs

1990
Protamine sulfate causes pulmonary hypertension and edema in isolated rat lungs.
    Journal of applied physiology (Bethesda, Md. : 1985), 1987, Volume: 62, Issue:4

    Topics: Animals; Blood Pressure; Capillary Permeability; Diphenhydramine; Heparin; Hypertension, Pulmonary;

1987
Effect of antihistaminic drugs on hypoxic pulmonary hypertension.
    The American journal of cardiology, 1973, Volume: 31, Issue:6

    Topics: Animals; Blood Pressure; Chlorpheniramine; Diphenhydramine; Dogs; Female; Histamine H1 Antagonists;

1973