Page last updated: 2024-10-26

diphenhydramine and Pruritus

diphenhydramine has been researched along with Pruritus in 46 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Pruritus: An intense itching sensation that produces the urge to rub or scratch the skin to obtain relief.

Research Excerpts

ExcerptRelevanceReference
"Ondansetron is as effective as diphenhydramine in relieving pruritus caused by SA morphine in patients undergoing a cesarean delivery."9.14Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. ( Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW, 2010)
"We examined the efficacy of epidural butorphanol to either prevent or relieve pruritus associated with epidural morphine infusion in children."9.09Continuous epidural butorphanol relieves pruritus associated with epidural morphine infusions in children. ( Gregg, T; Gunter, JB; McAuliffe, J; Sweeney, DM; Varughese, AM; Weidner, N, 2000)
"Ondansetron prophylaxis significantly decreases the incidence of pruritus, a common side effect of intrathecal morphine used to treat postcesarean delivery pain."9.09Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. ( Chan, WH; Chen, LK; Chen, YP; Lin, CJ; Lin, CS; Sun, WZ; Tsai, SK; Wang, MJ; Yeh, HM, 2000)
"Eighty patients, undergoing elective Caesarean section under spinal anaesthesia, were randomized, in a prospective, double-blind trial, to receive either nalbuphine (Group NAL) or diphenhydramine (Group DIP) for the treatment of SAB morphine-induced pruritus."9.08Treatment of intrathecal morphine-induced pruritus following caesarean section. ( Alhashemi, JA; Crosby, ET; Duffy, PJ; Gallant, C; Grodecki, W; Hull, KA, 1997)
"A double-blind crossover study of inhibition of histamine-induced pruritus by three commonly prescribed antihistamines was conducted on 28 normal subjects."9.04Suppression of histamine-induced pruritus by three antihistaminic drugs. ( Cohan, R; Leifer, KN; Rhoades, RB; Wittig, HJ, 1975)
"A 28-year-old nulliparous patient at 41 weeks of gestation was treated for pruritus with intravenous diphenhydramine after epidural administration of fentanyl."7.85Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration. ( Abernathy, A; Alsina, L; Egerman, R; Greer, J, 2017)
"A cream that contains menthol and diphenhydramine is widely prepared in hospital pharmacies and prescribed to patients for the treatment of pruritus associated with chronic kidney disease."7.81Magnetic resonance imaging study on the physical stability of menthol and diphenhydramine cream for the treatment of chronic kidney disease-associated pruritus. ( Machida, Y; Onuki, Y; Sakurai, S; Seike, C; Takayama, K; Yokawa, T, 2015)
"To report a case of delirium with hallucinations presumably caused by the combination of diphenhydramine and linezolid."7.72Acute delirium associated with combined diphenhydramine and linezolid use. ( Serio, RN, 2004)
"Famotidine was found to reduce pruritus associated with acute urticaria, intensity of urticaria, and body surface area affected by urticaria without causing sedation."6.69Famotidine in the treatment of acute urticaria. ( Harter, PM; Watson, NT; Weiss, EL, 2000)
"Ondansetron is as effective as diphenhydramine in relieving pruritus caused by SA morphine in patients undergoing a cesarean delivery."5.14Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. ( Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW, 2010)
"We examined the efficacy of epidural butorphanol to either prevent or relieve pruritus associated with epidural morphine infusion in children."5.09Continuous epidural butorphanol relieves pruritus associated with epidural morphine infusions in children. ( Gregg, T; Gunter, JB; McAuliffe, J; Sweeney, DM; Varughese, AM; Weidner, N, 2000)
"Ondansetron prophylaxis significantly decreases the incidence of pruritus, a common side effect of intrathecal morphine used to treat postcesarean delivery pain."5.09Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. ( Chan, WH; Chen, LK; Chen, YP; Lin, CJ; Lin, CS; Sun, WZ; Tsai, SK; Wang, MJ; Yeh, HM, 2000)
"Eighty patients, undergoing elective Caesarean section under spinal anaesthesia, were randomized, in a prospective, double-blind trial, to receive either nalbuphine (Group NAL) or diphenhydramine (Group DIP) for the treatment of SAB morphine-induced pruritus."5.08Treatment of intrathecal morphine-induced pruritus following caesarean section. ( Alhashemi, JA; Crosby, ET; Duffy, PJ; Gallant, C; Grodecki, W; Hull, KA, 1997)
"Of the 35 patients with pruritus, all 12 receiving diphenhydramine placebo had clinically significant relief compared with six of ten (60%) receiving cimetidine plus placebo (P = ."5.07Histamine antagonists in the treatment of acute allergic reactions. ( Caravati, EM; Hartsell, SC; Martinez, JC; Runge, JW; Williamson, SG, 1992)
"The red man syndrome (RMS) is the most common toxicity of vancomycin therapy."5.07Red man syndrome: incidence, etiology, and prophylaxis. ( Mascola, JR; Oldfield, EC; Wallace, MR, 1991)
"A double-blind crossover study of inhibition of histamine-induced pruritus by three commonly prescribed antihistamines was conducted on 28 normal subjects."5.04Suppression of histamine-induced pruritus by three antihistaminic drugs. ( Cohan, R; Leifer, KN; Rhoades, RB; Wittig, HJ, 1975)
"Only four large, randomized, double-blind, placebo-controlled clinical trials with definitive conclusions (grade A) support the use of topical antihistaminic agents, specifically topical doxepin, for relief of pruritus."4.86An evidence-based review of the efficacy of topical antihistamines in the relief of pruritus. ( Eschler, DC; Klein, PA, 2010)
"Diphenhydramine hydrochloride is an antihistamine with anticholinergic properties that is frequently used both orally and topically for the temporary relief of pruritus."4.78Diphenhydramine toxicity in three children with varicella-zoster infection. ( Chan, CY; Wallander, KA, 1991)
"A 28-year-old nulliparous patient at 41 weeks of gestation was treated for pruritus with intravenous diphenhydramine after epidural administration of fentanyl."3.85Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration. ( Abernathy, A; Alsina, L; Egerman, R; Greer, J, 2017)
"Diphenhydramine (DPH) is most commonly used via oral, topical, intramuscular (IM) and intravenous (IV) routes for the palliation of pruritus, treatment of extrapyramidal symptoms, management of parkinsonism and for allergic reactions."3.85Safe Use of Subcutaneous Diphenhydramine in the Inpatient Hospice Unit. ( Chen, A; Cooney, GA; Gonzalez, F; Hickey, T; Levene, R; Loquias, EJ; Roshan, R; Zelhof, R, 2017)
"A cream that contains menthol and diphenhydramine is widely prepared in hospital pharmacies and prescribed to patients for the treatment of pruritus associated with chronic kidney disease."3.81Magnetic resonance imaging study on the physical stability of menthol and diphenhydramine cream for the treatment of chronic kidney disease-associated pruritus. ( Machida, Y; Onuki, Y; Sakurai, S; Seike, C; Takayama, K; Yokawa, T, 2015)
"To report a case of delirium with hallucinations presumably caused by the combination of diphenhydramine and linezolid."3.72Acute delirium associated with combined diphenhydramine and linezolid use. ( Serio, RN, 2004)
"A 46-year-old woman developed an anaphylactic reaction during percutaneous coronary intervention after she was pretreated with prednisone and diphenhydramine for a known allergy to iodine."3.71Potential anaphylactic shock with abciximab readministration. ( Hamel, D; Palisaitis, DA; Pharand, C, 2002)
"Anti-allergic effects (types I and IV) of the 70% ethanol extract (CM-ext) obtained from Cnidii Monnieri Fructus (dried fruits of Cnidium monnieri) were investigated on 48 h homologous passive cutaneous anaphylaxis (PCA), 2, 4-dinitrofluorobenzene (DNFB)-induced contact dermatitis and picryl chloride (PC)-induced contact dermatitis in experimental animals."3.71Anti-allergic effects of cnidii monnieri fructus (dried fruits of Cnidium monnieri) and its major component, osthol. ( Ido, Y; Kubo, M; Matsuda, H; Tomohiro, N, 2002)
"A 52-year-old man developed contact and photoallergic dermatitis caused by diphenhydramine hydrochloride as well as contact dermatitis from paraphenylenediamine."3.65Allergic and photoallergic dermatitis from diphenhydramine. ( Horio, T, 1976)
"Famotidine was found to reduce pruritus associated with acute urticaria, intensity of urticaria, and body surface area affected by urticaria without causing sedation."2.69Famotidine in the treatment of acute urticaria. ( Harter, PM; Watson, NT; Weiss, EL, 2000)
"In order to offer an effective treatment of pruritus, our patient underwent ileal bypass and after a 2-month period free of symptoms, unexpectedly relapsed after a Rota viral infection."1.91Ileal bypass for pruritus relief in a 3-year-old boy with advanced progressive familial intrahepatic cholestasis: how effective is it? ( Dimopoulou, A; Dimopoulou, D; Fessatou, S; Kontaki, E; Vaos, G; Zavras, N, 2023)
"Pruritus is one of the most common complaints among patients who visit physicians."1.32Over-the-counter topical antipruritic agents are commonly recommended by office-based physicians: an analysis of US practice patterns. ( Duque, MI; Fleischer, AB; Vogel, CA; Yosipovitch, G, 2004)

Research

Studies (46)

TimeframeStudies, this research(%)All Research%
pre-199014 (30.43)18.7374
1990's7 (15.22)18.2507
2000's9 (19.57)29.6817
2010's14 (30.43)24.3611
2020's2 (4.35)2.80

Authors

AuthorsStudies
DiMauro, EF1
Altmann, S1
Berry, LM1
Bregman, H1
Chakka, N1
Chu-Moyer, M1
Bojic, EF1
Foti, RS1
Fremeau, R1
Gao, H1
Gunaydin, H1
Guzman-Perez, A1
Hall, BE1
Huang, H1
Jarosh, M1
Kornecook, T1
Lee, J1
Ligutti, J2
Liu, D2
Moyer, BD2
Ortuno, D1
Rose, PE1
Schenkel, LB1
Taborn, K1
Wang, J1
Wang, Y1
Yu, V1
Weiss, MM1
Wu, B1
Murray, JK1
Andrews, KL1
Sham, K1
Long, J1
Aral, J1
Amagasu, S1
Zou, A1
Min, X1
Wang, Z1
Ilch, CP1
Kornecook, TJ1
Lin, MJ1
Be, X1
Miranda, LP1
Biswas, K1
Solinski, HJ1
Dranchak, P1
Oliphant, E1
Gu, X1
Earnest, TW1
Braisted, J1
Inglese, J1
Hoon, MA1
Dimopoulou, A1
Dimopoulou, D1
Zavras, N1
Kontaki, E1
Vaos, G1
Fessatou, S1
Hawash, A1
Nguyen, T1
Mantilla, A1
Emesiani, C1
Meckfessel, M1
Abernathy, A1
Alsina, L1
Greer, J1
Egerman, R1
Ngo, SY1
Rabbat, JC1
Montagnese, TA1
Setty, M1
Papoiu, AD1
Valdes-Rodriguez, R1
Nattkemper, LA1
Chan, YH1
Hahn, GS1
Yosipovitch, G2
Zakaria, K1
Onuki, Y1
Machida, Y1
Yokawa, T1
Seike, C1
Sakurai, S1
Takayama, K1
Chen, A1
Loquias, EJ1
Roshan, R1
Levene, R1
Zelhof, R1
Hickey, T1
Cooney, GA1
Gonzalez, F1
Siddik-Sayyid, SM1
Yazbeck-Karam, VG1
Zahreddine, BW1
Adham, AM1
Dagher, CM1
Saasouh, WA1
Aouad, MT1
Sheth, SS1
Posner, MA1
Eschler, DC1
Klein, PA1
Marino, M1
Huang, P1
Malkmus, S1
Robertshaw, E1
Mac, EA1
Shatterman, Y1
Yaksh, TL1
Holdiness, MR1
VENDEL, S1
KASUMBEILI, KhG1
ROWE, RG1
YOUNG, MJ1
MacGinnitie, AJ1
Walensky, LD1
Turvey, SE1
Orange, JS1
Bonilla, FA1
Silverman, LB1
Oettgen, H1
Serio, RN1
TELLO, EE1
GITMAN, SM1
Duque, MI1
Vogel, CA1
Fleischer, AB1
PHILIP, AJ1
ORECKLIN, L1
Garafalo, J1
Kaplan, AP1
Bernstein, JE1
Whitney, DH1
Soltani, K1
Baker, BA1
Cacchione, JG1
Alhashemi, JA1
Crosby, ET1
Grodecki, W1
Duffy, PJ1
Hull, KA1
Gallant, C1
Renz, C1
Lynch, J1
Thurn, J1
Moss, J1
Gunter, JB1
McAuliffe, J1
Gregg, T1
Weidner, N1
Varughese, AM1
Sweeney, DM1
Watson, NT1
Weiss, EL1
Harter, PM1
Yeh, HM1
Chen, LK1
Lin, CJ1
Chan, WH1
Chen, YP1
Lin, CS1
Sun, WZ1
Wang, MJ1
Tsai, SK1
Pharand, C1
Palisaitis, DA1
Hamel, D1
Matsuda, H1
Tomohiro, N1
Ido, Y1
Kubo, M1
Rhoades, RB1
Leifer, KN1
Cohan, R1
Wittig, HJ1
Horio, T1
Runge, JW1
Martinez, JC1
Caravati, EM1
Williamson, SG1
Hartsell, SC1
Bernhardt, DT1
Wallace, MR1
Mascola, JR1
Oldfield, EC1
Chan, CY1
Wallander, KA1
Glukhen'kiĭ, BT1
Grando, SA1
Davenport, PM1
Wilhelm, RE1
Dadiomova, VG1
Zastenker, FS1
Bakulina, KI1
Kundel', LM1

Clinical Trials (2)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Comparison Between Ondansetron 8 mg and Lidocain 40 mg in Preventing Pain Due to Propofol Injection[NCT03134612]Phase 2104 participants (Actual)Interventional2016-07-31Completed
IRB-HSR# 14583: Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients[NCT01414777]Phase 2/Phase 368 participants (Actual)Interventional2009-11-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

2 reviews available for diphenhydramine and Pruritus

ArticleYear
An evidence-based review of the efficacy of topical antihistamines in the relief of pruritus.
    Journal of drugs in dermatology : JDD, 2010, Volume: 9, Issue:8

    Topics: Administration, Cutaneous; Diphenhydramine; Doxepin; Evidence-Based Medicine; Histamine Antagonists;

2010
Diphenhydramine toxicity in three children with varicella-zoster infection.
    DICP : the annals of pharmacotherapy, 1991, Volume: 25, Issue:2

    Topics: Administration, Cutaneous; Administration, Oral; Chickenpox; Child; Child, Preschool; Diphenhydramin

1991

Trials

12 trials available for diphenhydramine and Pruritus

ArticleYear
Individual Article: Evaluation of Efficacy and Tolerability of Two Over-the-Counter Eczema Itch Relief Products.
    Journal of drugs in dermatology : JDD, 2023, Oct-01, Volume: 22, Issue:10

    Topics: Adult; Diphenhydramine; Eczema; Female; Humans; Male; Middle Aged; Nonprescription Drugs; Pain; Pare

2023
A novel topical formulation containing strontium chloride significantly reduces the intensity and duration of cowhage-induced itch.
    Acta dermato-venereologica, 2013, Sep-04, Volume: 93, Issue:5

    Topics: Administration, Cutaneous; Adult; Analysis of Variance; Antipruritics; Chemistry, Pharmaceutical; De

2013
Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery.
    Acta anaesthesiologica Scandinavica, 2010, Volume: 54, Issue:6

    Topics: Adult; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Hum

2010
Inhibition of histamine-induced pruritus by topical tricyclic antidepressants.
    Journal of the American Academy of Dermatology, 1981, Volume: 5, Issue:5

    Topics: Administration, Topical; Amitriptyline; Antidepressive Agents, Tricyclic; Diphenhydramine; Double-Bl

1981
Treatment of intrathecal morphine-induced pruritus following caesarean section.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 1997, Volume: 44, Issue:10

    Topics: Adult; Analgesics, Opioid; Antipruritics; Cesarean Section; Diphenhydramine; Double-Blind Method; Fe

1997
Histamine release during rapid vancomycin administration.
    Inflammation research : official journal of the European Histamine Research Society ... [et al.], 1998, Volume: 47 Suppl 1

    Topics: Anti-Bacterial Agents; Cimetidine; Diphenhydramine; Double-Blind Method; Drug Hypersensitivity; Exan

1998
Continuous epidural butorphanol relieves pruritus associated with epidural morphine infusions in children.
    Paediatric anaesthesia, 2000, Volume: 10, Issue:2

    Topics: Adolescent; Analgesia, Epidural; Analgesics, Opioid; Anesthetics, Local; Antipruritics; Bupivacaine;

2000
Famotidine in the treatment of acute urticaria.
    Clinical and experimental dermatology, 2000, Volume: 25, Issue:3

    Topics: Acute Disease; Adolescent; Adult; Antipruritics; Diphenhydramine; Double-Blind Method; Famotidine; F

2000
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca

2000
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca

2000
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca

2000
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
    Anesthesia and analgesia, 2000, Volume: 91, Issue:1

    Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca

2000
Suppression of histamine-induced pruritus by three antihistaminic drugs.
    The Journal of allergy and clinical immunology, 1975, Volume: 55, Issue:3

    Topics: Adolescent; Adult; Clinical Trials as Topic; Cyproheptadine; Differential Threshold; Diphenhydramine

1975
Histamine antagonists in the treatment of acute allergic reactions.
    Annals of emergency medicine, 1992, Volume: 21, Issue:3

    Topics: Adult; Anaphylaxis; Blood Pressure; Cimetidine; Diphenhydramine; Double-Blind Method; Drug Therapy,

1992
Red man syndrome: incidence, etiology, and prophylaxis.
    The Journal of infectious diseases, 1991, Volume: 164, Issue:6

    Topics: Adult; Diphenhydramine; Double-Blind Method; Female; Flushing; Histamine; Humans; Male; Prospective

1991

Other Studies

32 other studies available for diphenhydramine and Pruritus

ArticleYear
Application of a Parallel Synthetic Strategy in the Discovery of Biaryl Acyl Sulfonamides as Efficient and Selective NaV1.7 Inhibitors.
    Journal of medicinal chemistry, 2016, 09-08, Volume: 59, Issue:17

    Topics: Animals; Benzamides; Cell Line; Female; Histamine; Humans; Male; Mice, Inbred C57BL; Microsomes, Liv

2016
Discovery of Tarantula Venom-Derived Na
    Journal of medicinal chemistry, 2018, 11-08, Volume: 61, Issue:21

    Topics: Animals; Drug Discovery; HEK293 Cells; Histamine; Humans; Mice; Molecular Docking Simulation; NAV1.7

2018
Inhibition of natriuretic peptide receptor 1 reduces itch in mice.
    Science translational medicine, 2019, 07-10, Volume: 11, Issue:500

    Topics: Animals; Behavior, Animal; Cell-Free System; Dermatitis, Contact; Disease Models, Animal; Ganglia, S

2019
Ileal bypass for pruritus relief in a 3-year-old boy with advanced progressive familial intrahepatic cholestasis: how effective is it?
    Folia medica, 2023, Feb-28, Volume: 65, Issue:1

    Topics: Child; Child, Preschool; Cholestasis; Cholestasis, Intrahepatic; Digestive System Surgical Procedure

2023
Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration.
    Obstetrics and gynecology, 2017, Volume: 130, Issue:2

    Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Cesarean Section; Diphenhydramine; Female; F

2017
Systemic IgE-mediated hypersensitivity reaction to topical polymyxin B.
    The journal of allergy and clinical immunology. In practice, 2019, Volume: 7, Issue:2

    Topics: Anti-Bacterial Agents; Bacitracin; Child; Diphenhydramine; Drug Combinations; Drug Hypersensitivity;

2019
A clinical report of the management of episodic idiopathic pruritus occurring during endodontic therapy.
    Journal of endodontics, 2013, Volume: 39, Issue:3

    Topics: Adult; Anesthesia, Local; Anesthetics, Local; Dental Anxiety; Diazepam; Diphenhydramine; Female; His

2013
Pruritic erythematous plaques.
    American family physician, 2014, Sep-01, Volume: 90, Issue:5

    Topics: Aged; Anti-Allergic Agents; Cetirizine; Diagnosis, Differential; Diphenhydramine; Female; Humans; My

2014
Magnetic resonance imaging study on the physical stability of menthol and diphenhydramine cream for the treatment of chronic kidney disease-associated pruritus.
    Chemical & pharmaceutical bulletin, 2015, Volume: 63, Issue:6

    Topics: Diphenhydramine; Drug Stability; Histamine H1 Antagonists; Humans; Hydrophobic and Hydrophilic Inter

2015
Safe Use of Subcutaneous Diphenhydramine in the Inpatient Hospice Unit.
    The American journal of hospice & palliative care, 2017, Volume: 34, Issue:10

    Topics: Adult; Aged; Aged, 80 and over; Basal Ganglia Diseases; Diphenhydramine; Female; Hospices; Humans; I

2017
Modified protocol for desensitization to glatiramer acetate.
    Annals of allergy, asthma & immunology : official publication of the American College of Allergy, Asthma, & Immunology, 2010, Volume: 105, Issue:2

    Topics: Adult; Chemotherapy, Adjuvant; Clinical Protocols; Desensitization, Immunologic; Diphenhydramine; Dr

2010
Development and validation of an automated system for detection and assessment of scratching in the rodent.
    Journal of neuroscience methods, 2012, Oct-15, Volume: 211, Issue:1

    Topics: Algorithms; Analog-Digital Conversion; Animals; Anti-Allergic Agents; Automation; Behavior, Animal;

2012
Rare systemic dermatologic reaction after pneumococcal vaccine administration.
    Southern medical journal, 2003, Volume: 96, Issue:1

    Topics: Aged; Anti-Allergic Agents; Anti-Inflammatory Agents; Diphenhydramine; Drug Eruptions; Humans; Hydro

2003
[Pruritus with varicella, treated with paradryl].
    Ugeskrift for laeger, 1956, Dec-20, Volume: 118, Issue:51

    Topics: Chickenpox; Diphenhydramine; Humans; Pruritus

1956
[Result of ambulatory dimedrol therapy of patients with pruritic dermatoses].
    Vestnik rentgenologii i radiologii, 1961, Volume: 35

    Topics: Diphenhydramine; Humans; Pruritus; Skin Diseases

1961
CLINICAL EVALUATION OF A NEW ANTIHISTAMINE, MEBROPHENHYDRAMINE.
    Applied therapeutics, 1963, Volume: 5

    Topics: Asthma; Dermatitis; Diphenhydramine; Histamine H1 Antagonists; Humans; Insect Bites and Stings; Phar

1963
Management of an anaphylactoid reaction to methotrexate with a stepwise graded challenge.
    Pediatric allergy and immunology : official publication of the European Society of Pediatric Allergy and Immunology, 2003, Volume: 14, Issue:5

    Topics: Adolescent; Anaphylaxis; Anti-Allergic Agents; Antimetabolites, Antineoplastic; Antipruritics; Diphe

2003
Acute delirium associated with combined diphenhydramine and linezolid use.
    The Annals of pharmacotherapy, 2004, Volume: 38, Issue:1

    Topics: Acetamides; Acute Disease; Delirium; Diphenhydramine; Drug Combinations; Drug Interactions; Duty to

2004
[Penetrasol-benedryl as local antipruritic].
    Revista medica de Cordoba, 1950, Volume: 38, Issue:9

    Topics: Antipruritics; Diphenhydramine; Humans; Pruritus

1950
[Dimedrol in the treatment of pruritic dermatoses].
    Sovetskaia meditsina, 1951, Volume: 4

    Topics: Diphenhydramine; Histamine Antagonists; Humans; Pruritus; Skin Diseases

1951
Over-the-counter topical antipruritic agents are commonly recommended by office-based physicians: an analysis of US practice patterns.
    The Journal of dermatological treatment, 2004, Volume: 15, Issue:3

    Topics: Adolescent; Adult; Ambulatory Care; Antipruritics; Child; Diphenhydramine; Drug Utilization; Female;

2004
Treatment of itching dermatoses with an ointment containing 2% diphenhydramine (benadryl hydrochloride).
    New York state journal of medicine, 1949, May-15, Volume: 49, Issue:10

    Topics: Diphenhydramine; Ointments; Pruritus; Salts; Skin Diseases

1949
Control of pruritus with diphenhydramine hydrochloride ointment.
    Archives of dermatology and syphilology, 1949, Volume: 60, Issue:4

    Topics: Diphenhydramine; Humans; Ointments; Pruritus

1949
Histamine release and therapy of severe dermatographism.
    The Journal of allergy and clinical immunology, 1981, Volume: 68, Issue:2

    Topics: Adolescent; Animals; Cyproheptadine; Diphenhydramine; Female; Histamine; Histamine Release; Humans;

1981
Dermatologic cross-sensitivity between diltiazem and amlodipine.
    The Annals of pharmacotherapy, 1994, Volume: 28, Issue:1

    Topics: Amlodipine; Diltiazem; Diphenhydramine; Drug Eruptions; Humans; Hydroxyzine; Male; Methylprednisolon

1994
Potential anaphylactic shock with abciximab readministration.
    Pharmacotherapy, 2002, Volume: 22, Issue:3

    Topics: Abciximab; Anaphylaxis; Anti-Inflammatory Agents; Antibodies, Monoclonal; Bradycardia; Diphenhydrami

2002
Anti-allergic effects of cnidii monnieri fructus (dried fruits of Cnidium monnieri) and its major component, osthol.
    Biological & pharmaceutical bulletin, 2002, Volume: 25, Issue:6

    Topics: Animals; Anti-Allergic Agents; Anti-Inflammatory Agents, Non-Steroidal; Cnidium; Coumarins; Dermatit

2002
Allergic and photoallergic dermatitis from diphenhydramine.
    Archives of dermatology, 1976, Volume: 112, Issue:8

    Topics: Dermatitis, Contact; Diphenhydramine; Drug Hypersensitivity; Humans; Male; Middle Aged; Photosensiti

1976
Topical diphenhydramine toxicity.
    Wisconsin medical journal, 1991, Volume: 90, Issue:8

    Topics: Administration, Topical; Chickenpox; Child; Delirium; Diphenhydramine; Humans; Male; Pruritus

1991
[Suppression of the activity of biologically active substances for the relief of itching in atopic dermatitis].
    Sovetskaia meditsina, 1985, Issue:9

    Topics: Aminocaproates; Aminocaproic Acid; Dermatitis, Atopic; Diphenhydramine; Drug Therapy, Combination; H

1985
An unusual vasculitis due to diphenhydramine. Cutaneous and central nervous system involvement.
    Archives of dermatology, 1965, Volume: 92, Issue:5

    Topics: Adult; Black or African American; Dermatitis, Atopic; Diphenhydramine; Drug Eruptions; Drug Hypersen

1965
[Nasal electrophoresis of dimedrol and calcium in pruritic dermatosis].
    Vestnik dermatologii i venerologii, 1969, Volume: 43, Issue:7

    Topics: Adult; Dermatitis, Exfoliative; Dermatomycoses; Diphenhydramine; Humans; Iontophoresis; Male; Middle

1969