diphenhydramine has been researched along with Pregnancy in 93 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Pregnancy: The status during which female mammals carry their developing young (EMBRYOS or FETUSES) in utero before birth, beginning from FERTILIZATION to BIRTH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison." | 9.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "Ondansetron is as effective as diphenhydramine in relieving pruritus caused by SA morphine in patients undergoing a cesarean delivery." | 9.14 | Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. ( Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW, 2010) |
| "Ondansetron prophylaxis significantly decreases the incidence of pruritus, a common side effect of intrathecal morphine used to treat postcesarean delivery pain." | 9.09 | Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. ( Chan, WH; Chen, LK; Chen, YP; Lin, CJ; Lin, CS; Sun, WZ; Tsai, SK; Wang, MJ; Yeh, HM, 2000) |
| "Eighty patients, undergoing elective Caesarean section under spinal anaesthesia, were randomized, in a prospective, double-blind trial, to receive either nalbuphine (Group NAL) or diphenhydramine (Group DIP) for the treatment of SAB morphine-induced pruritus." | 9.08 | Treatment of intrathecal morphine-induced pruritus following caesarean section. ( Alhashemi, JA; Crosby, ET; Duffy, PJ; Gallant, C; Grodecki, W; Hull, KA, 1997) |
| "A 28-year-old nulliparous patient at 41 weeks of gestation was treated for pruritus with intravenous diphenhydramine after epidural administration of fentanyl." | 7.85 | Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration. ( Abernathy, A; Alsina, L; Egerman, R; Greer, J, 2017) |
| "The new protocol consisting of the combination of metoclopramide and diphenhydramine appears to be a good option in the management of hyperemesis gravidarum." | 7.75 | Metoclopramide and diphenhydramine in the treatment of hyperemesis gravidarum: effectiveness and predictors of rehospitalisation. ( Bérard, A; Ferreira, E; Lacasse, A; Lagoutte, A, 2009) |
| "Droperidol and diphenhydramine infusion is a beneficial, cost-effective therapy for the treatment of hyperemesis gravidarum." | 7.69 | Droperidol and diphenhydramine in the management of hyperemesis gravidarum. ( Asrat, T; Briggs, GG; Nageotte, MP; Towers, CV, 1996) |
| " Further workup revealed urinary diphenhydramine levels suggesting drug overdose." | 7.69 | Diphenhydramine overdose during pregnancy: lessons from the past. ( Brost, BC; Newman, RB; Scardo, JA, 1996) |
| " In order to evaluate the relative contribution of fostering procedures in the analysis of the development of rats prenatally exposed to diphenhydramine (20 mg/kg/day, sc) the weight gain of litters fostered or not by their biological mothers were examined from 2-21 days of age." | 7.68 | Prenatal versus postnatal effects on offspring weight gain of rats exposed to diphenhydramine: a critical evaluation of fostering procedures in rats. ( Bernardi, MM; Chiavegatto, S, 1991) |
| "We investigated whether metoclopramide administered with diphenhydramine (MAD) relieves headache in pregnant women when acetaminophen alone is ineffective, using codeine for comparison." | 5.27 | Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study). ( Childress, KMS; Dothager, C; Gavard, JA; Laska, C; Lebovitz, S; Mostello, DJ, 2018) |
| "Ondansetron is as effective as diphenhydramine in relieving pruritus caused by SA morphine in patients undergoing a cesarean delivery." | 5.14 | Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery. ( Adham, AM; Aouad, MT; Dagher, CM; Saasouh, WA; Siddik-Sayyid, SM; Yazbeck-Karam, VG; Zahreddine, BW, 2010) |
| "Ondansetron prophylaxis significantly decreases the incidence of pruritus, a common side effect of intrathecal morphine used to treat postcesarean delivery pain." | 5.09 | Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery. ( Chan, WH; Chen, LK; Chen, YP; Lin, CJ; Lin, CS; Sun, WZ; Tsai, SK; Wang, MJ; Yeh, HM, 2000) |
| "Eighty patients, undergoing elective Caesarean section under spinal anaesthesia, were randomized, in a prospective, double-blind trial, to receive either nalbuphine (Group NAL) or diphenhydramine (Group DIP) for the treatment of SAB morphine-induced pruritus." | 5.08 | Treatment of intrathecal morphine-induced pruritus following caesarean section. ( Alhashemi, JA; Crosby, ET; Duffy, PJ; Gallant, C; Grodecki, W; Hull, KA, 1997) |
| "We report a case of laminaria hypersensitivity treated with diphenhydramine and corticosteroids." | 4.91 | Hypersensitivity to laminaria: a case report and review of literature. ( Chen, KT; Figueroa, MM; Jacobs, A; Lunde, B; Sierra, T, 2015) |
| "A 28-year-old nulliparous patient at 41 weeks of gestation was treated for pruritus with intravenous diphenhydramine after epidural administration of fentanyl." | 3.85 | Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration. ( Abernathy, A; Alsina, L; Egerman, R; Greer, J, 2017) |
| "The new protocol consisting of the combination of metoclopramide and diphenhydramine appears to be a good option in the management of hyperemesis gravidarum." | 3.75 | Metoclopramide and diphenhydramine in the treatment of hyperemesis gravidarum: effectiveness and predictors of rehospitalisation. ( Bérard, A; Ferreira, E; Lacasse, A; Lagoutte, A, 2009) |
| "A pregnant patient consulted her physician after discovering that a diphenhydramine preparation (Benadryl elixir) she used for allergy symptoms during the first trimester of her pregnancy contained 15% alcohol." | 3.73 | Exposure to alcohol-containing medications during pregnancy. ( Finkelstein, Y; Garcia-Bournissen, F; Koren, G; Rezvani, M, 2006) |
| "Ingestion of the anticonvulsant drug valproic acid and of the angiotensin converting enzyme inhibitor captopril during pregnancy has been associated with abnormal fetal outcome in humans." | 3.69 | Evaluation of the rat embryo culture system as a predictive test for human teratogens. ( Buttar, HS; Guest, I; Smith, S; Varma, DR, 1994) |
| "Droperidol and diphenhydramine infusion is a beneficial, cost-effective therapy for the treatment of hyperemesis gravidarum." | 3.69 | Droperidol and diphenhydramine in the management of hyperemesis gravidarum. ( Asrat, T; Briggs, GG; Nageotte, MP; Towers, CV, 1996) |
| " Further workup revealed urinary diphenhydramine levels suggesting drug overdose." | 3.69 | Diphenhydramine overdose during pregnancy: lessons from the past. ( Brost, BC; Newman, RB; Scardo, JA, 1996) |
| " In order to evaluate the relative contribution of fostering procedures in the analysis of the development of rats prenatally exposed to diphenhydramine (20 mg/kg/day, sc) the weight gain of litters fostered or not by their biological mothers were examined from 2-21 days of age." | 3.68 | Prenatal versus postnatal effects on offspring weight gain of rats exposed to diphenhydramine: a critical evaluation of fostering procedures in rats. ( Bernardi, MM; Chiavegatto, S, 1991) |
| "Fifty-four pregnant women with insomnia were randomly assigned to trazodone, diphenhydramine, or placebo treatment." | 2.78 | Insomnia treatment in the third trimester of pregnancy reduces postpartum depression symptoms: a randomized clinical trial. ( Emamian, F; Ghadami, MR; Khazaie, H; Knight, DC; Tahmasian, M, 2013) |
| "Consequently, pregnancy is a time when headache diagnosis can influence maternal and fetal interventions." | 2.72 | Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review. ( Bushman, ET; Cozzi, G; Digre, K; Sinkey, RG; Smith, CH; Varner, MW, 2021) |
| " Pyridoxine is considered safe for use during pregnancy, but its efficacy in treating nausea and vomiting has not been determined." | 2.37 | Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy. ( Leathem, AM, 1986) |
| "Lidocaine was the predominant finding followed by caffeine, and diphenhydramine all of which could result from non-illicit drug exposure, however, there were positives for levamisole, phenacetin, noxiptillin and xylazine none of which are approved in the United States for human therapeutic use." | 1.72 | Qualitative LC-Q-TOF Analysis of Umbilical Cord Tissue via Data-Dependent Acquisition as an Indicator of In Utero Exposure to Toxic Adulterating Substances. ( Browne, T; Cervantes, A; Logan, BK; Nelson, BN; Strathmann, FG, 2022) |
| "Migraine is a common problem in pregnancy; however, migraine treatment is challenging in pregnant women for fears of medication teratogenicity and lack of data in this population." | 1.51 | Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study. ( Hamilton, KT; Robbins, MS, 2019) |
| "Dyspareunia, vaginitis and dysfunctional uterine bleeding (DUB) are common problems which, despite their polygenicity, commonly appear idiopathic and treatment-refractory." | 1.51 | Successful mast-cell-targeted treatment of chronic dyspareunia, vaginitis, and dysfunctional uterine bleeding. ( Afrin, LB; Dempsey, TT; Dorff, SR; Rosenthal, LS, 2019) |
| "Hair specimen is necessary to complement blood and/or urine analyses as it permits differentiation of a single exposure from chronic use of a drug by segmentation of the hair for a stated growth period." | 1.42 | Contribution of in utero drug exposure when interpreting hair results in young children. ( Kintz, P, 2015) |
| "Differentiation of pemphigoid gestationis from pruritic urticarial papules and plaques of pregnancy is essential because management and outcomes differ." | 1.36 | Pemphigoid gestationis. ( Kamino, H; Lu, PD; Ralston, J; Stein, JA, 2010) |
| "Diphenhydramine is an adequate alternative of local anesthetics in patients with history of hypersensitivity to local anesthetics." | 1.31 | [Diphenhydramine is useful in a parturient with hypersensitivity to local anesthetics to manage her delivery]. ( Hiruta, M; Horikawa, Y; Kawakami, T; Mitsuhata, H; Saito, J; Seo, N, 2002) |
| "Diphenhydramine was administered by simultaneous intravenous bolus injection and infusion to steady state given 48 h apart, to the ewe and the fetus on separate occasions." | 1.29 | Transplacental and nonplacental clearances of diphenhydramine in the chronically instrumented pregnant sheep. ( Axelson, JE; Rurak, DW; Taylor, SM; Yoo, SD, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 50 (53.76) | 18.7374 |
| 1990's | 16 (17.20) | 18.2507 |
| 2000's | 10 (10.75) | 29.6817 |
| 2010's | 13 (13.98) | 24.3611 |
| 2020's | 4 (4.30) | 2.80 |
| Authors | Studies |
|---|---|
| Marchais-Oberwinkler, S | 1 |
| Wetzel, M | 1 |
| Ziegler, E | 1 |
| Kruchten, P | 1 |
| Werth, R | 1 |
| Henn, C | 1 |
| Hartmann, RW | 1 |
| Frotscher, M | 1 |
| Nelson, BN | 1 |
| Strathmann, FG | 1 |
| Browne, T | 1 |
| Cervantes, A | 1 |
| Logan, BK | 1 |
| LoGiudice, JA | 1 |
| Holland, E | 1 |
| Esposito, CP | 1 |
| Qutob, HMH | 1 |
| Saad, RA | 1 |
| Bali, H | 1 |
| Osailan, A | 1 |
| Jaber, J | 1 |
| Alzahrani, E | 1 |
| Alyami, J | 1 |
| Elsayed, H | 1 |
| Alserihi, R | 1 |
| Shaikhomar, OA | 1 |
| Divya, KM | 1 |
| Savitha, DP | 1 |
| Krishna, GA | 1 |
| Dhanya, TM | 1 |
| Mohanan, PV | 1 |
| Shah, SF | 1 |
| Jafry, AT | 1 |
| Hussain, G | 1 |
| Kazim, AH | 1 |
| Ali, M | 1 |
| Rivani, E | 1 |
| Endraswari, PD | 1 |
| Widodo, ADW | 1 |
| Khalil, MR | 1 |
| Guldberg, R | 1 |
| Nørgård, BM | 1 |
| Uldbjerg, N | 1 |
| Wehberg, S | 1 |
| Fowobaje, KR | 1 |
| Mashood, LO | 1 |
| Ekholuenetale, M | 1 |
| Ibidoja, OJ | 1 |
| Romagnoli, A | 1 |
| D'Agostino, M | 1 |
| Pavoni, E | 1 |
| Ardiccioni, C | 1 |
| Motta, S | 1 |
| Crippa, P | 1 |
| Biagetti, G | 1 |
| Notarstefano, V | 1 |
| Rexha, J | 1 |
| Perta, N | 1 |
| Barocci, S | 1 |
| Costabile, BK | 1 |
| Colasurdo, G | 1 |
| Caucci, S | 1 |
| Mencarelli, D | 1 |
| Turchetti, C | 1 |
| Farina, M | 1 |
| Pierantoni, L | 1 |
| La Teana, A | 1 |
| Al Hadi, R | 1 |
| Cicconardi, F | 1 |
| Chinappi, M | 1 |
| Trucchi, E | 1 |
| Mancia, F | 1 |
| Menzo, S | 1 |
| Morozzo Della Rocca, B | 1 |
| D'Annessa, I | 1 |
| Di Marino, D | 1 |
| Choya, A | 1 |
| de Rivas, B | 1 |
| Gutiérrez-Ortiz, JI | 1 |
| López-Fonseca, R | 1 |
| Xu, S | 1 |
| Cheng, B | 1 |
| Huang, Z | 1 |
| Liu, T | 1 |
| Li, Y | 1 |
| Jiang, L | 1 |
| Guo, W | 1 |
| Xiong, J | 1 |
| Amirazodi, M | 1 |
| Daryanoosh, F | 1 |
| Mehrabi, A | 1 |
| Gaeini, A | 1 |
| Koushkie Jahromi, M | 1 |
| Salesi, M | 1 |
| Zarifkar, AH | 1 |
| Studeny, P | 1 |
| Netukova, M | 1 |
| Nemcokova, M | 1 |
| Klimesova, YM | 1 |
| Krizova, D | 1 |
| Kang, H | 1 |
| Tao, Y | 1 |
| Zhang, Q | 1 |
| Sha, D | 1 |
| Chen, Y | 1 |
| Yao, J | 1 |
| Gao, Y | 1 |
| Liu, J | 1 |
| Ji, L | 1 |
| Shi, P | 1 |
| Shi, C | 1 |
| Wu, YL | 1 |
| Wright, AI | 1 |
| M El-Metwaly, N | 1 |
| A Katouah, H | 1 |
| El-Desouky, MG | 1 |
| El-Bindary, AA | 1 |
| El-Bindary, MA | 1 |
| Kostakis, ID | 1 |
| Raptis, DA | 1 |
| Davidson, BR | 1 |
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| Pissanou, T | 1 |
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| Hughes, AM | 1 |
| Sanderson, E | 1 |
| Morris, T | 1 |
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| Tesli, M | 1 |
| Ask, H | 1 |
| Reichborn-Kjennerud, T | 1 |
| Andreassen, OA | 1 |
| Magnus, P | 1 |
| Helgeland, Ø | 1 |
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| Njølstad, P | 1 |
| Davey Smith, G | 1 |
| Havdahl, A | 1 |
| Howe, LD | 1 |
| Davies, NM | 1 |
| Amrillah, T | 1 |
| Prasetio, A | 1 |
| Supandi, AR | 1 |
| Sidiq, DH | 1 |
| Putra, FS | 1 |
| Nugroho, MA | 1 |
| Salsabilla, Z | 1 |
| Azmi, R | 1 |
| Grammatikopoulos, P | 1 |
| Bouloumis, T | 1 |
| Steinhauer, S | 1 |
| Mironov, VS | 2 |
| Bazhenova, TA | 2 |
| Manakin, YV | 2 |
| Yagubskii, EB | 2 |
| Yakushev, IA | 1 |
| Gilmutdinov, IF | 1 |
| Simonov, SV | 1 |
| Lan, K | 1 |
| Yang, H | 1 |
| Zheng, J | 1 |
| Hu, H | 1 |
| Zhu, T | 1 |
| Zou, X | 1 |
| Hu, B | 1 |
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| Olokede, O | 1 |
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| Holtzapple, M | 1 |
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| Bauermeister, JA | 1 |
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| Zimmerman, MA | 1 |
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| Bonar, EE | 1 |
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| Digre, K | 1 |
| Abernathy, A | 1 |
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| Egerman, R | 1 |
| Childress, KMS | 1 |
| Dothager, C | 1 |
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| DEFEO, VJ | 1 |
| WINBERG, J | 1 |
| STEIN, ID | 1 |
| MACAULAY, AI | 1 |
| ROSENVASSER, EB | 1 |
| CARPANO, A | 1 |
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| Ujházy, E | 2 |
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| Tonn, GR | 6 |
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| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| [NCT05753943] | 0 participants | Expanded Access | No longer available | ||||
| Feasibility and Efficacy of an Internet-delivered Cognitive-behavioral Intervention for Insomnia in a National Cohort of Danish Breast Cancer Survivors[NCT02444026] | 225 participants (Anticipated) | Interventional | 2014-12-31 | Recruiting | |||
| Comparison Between Ondansetron 8 mg and Lidocain 40 mg in Preventing Pain Due to Propofol Injection[NCT03134612] | Phase 2 | 104 participants (Actual) | Interventional | 2016-07-31 | Completed | ||
| IRB-HSR# 14583: Intravenous Ondansetron to Attenuate the Hypotensive, Bradycardic Response to Spinal Anesthesia in Healthy Parturients[NCT01414777] | Phase 2/Phase 3 | 68 participants (Actual) | Interventional | 2009-11-30 | Completed | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
5 reviews available for diphenhydramine and Pregnancy
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Randomized Controlled Trials of Headache Treatments in Pregnancy: A Systematic Review.
Topics: Acupuncture Analgesia; Analgesics; Biofeedback, Psychology; Codeine; Complementary Therapies; Diphen | 2021 |
Hypersensitivity to laminaria: a case report and review of literature.
Topics: Abortion, Induced; Adrenal Cortex Hormones; Adult; Anaphylaxis; Anti-Allergic Agents; Dilatation; Di | 2015 |
New approaches for drug and kinetic analysis in the maternal-fetal unit.
Topics: Animals; Diphenhydramine; Female; Fetus; Labetalol; Metoclopramide; Pregnancy; Pregnancy, Animal; Sh | 1995 |
Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy.
Topics: Antiemetics; Antipsychotic Agents; Dicyclomine; Diphenhydramine; Doxylamine; Drug Combinations; Fema | 1986 |
7 trials available for diphenhydramine and Pregnancy
| Article | Year |
|---|---|
Impact of dexamethasone and tocilizumab on hematological parameters in COVID-19 patients with chronic disease.
Topics: Acetaminophen; Acetylcarnitine; Acetylcholinesterase; Acids; Acinetobacter baumannii; Acinetobacter | 2022 |
Metoclopramide and Diphenhydramine: A Randomized Controlled Trial of a Treatment for Headache in Pregnancy when Acetaminophen Alone Is Ineffective (MAD Headache Study).
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Codeine; Diphenhydramine; Double-Blind Method; Drug A | 2018 |
Insomnia treatment in the third trimester of pregnancy reduces postpartum depression symptoms: a randomized clinical trial.
Topics: Actigraphy; Adult; Antidepressive Agents, Second-Generation; Depression; Depression, Postpartum; Dip | 2013 |
Ondansetron is as effective as diphenhydramine for treatment of morphine-induced pruritus after cesarean delivery.
Topics: Adult; Cesarean Section; Diphenhydramine; Double-Blind Method; Female; Histamine H1 Antagonists; Hum | 2010 |
Treatment of intrathecal morphine-induced pruritus following caesarean section.
Topics: Adult; Analgesics, Opioid; Antipruritics; Cesarean Section; Diphenhydramine; Double-Blind Method; Fe | 1997 |
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca | 2000 |
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca | 2000 |
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca | 2000 |
Prophylactic intravenous ondansetron reduces the incidence of intrathecal morphine-induced pruritus in patients undergoing cesarean delivery.
Topics: Adolescent; Adult; Analgesia, Obstetrical; Analgesics, Opioid; Anesthesia, Spinal; Anesthetics, Loca | 2000 |
In vivo and in vitro chromosomal damage induced by LSD-25.
Topics: Adult; Child; Child, Preschool; Chlorpromazine; Chromosome Aberrations; Chromosome Disorders; Clinic | 1967 |
82 other studies available for diphenhydramine and Pregnancy
| Article | Year |
|---|---|
New drug-like hydroxyphenylnaphthol steroidomimetics as potent and selective 17β-hydroxysteroid dehydrogenase type 1 inhibitors for the treatment of estrogen-dependent diseases.
Topics: 17-Hydroxysteroid Dehydrogenases; Administration, Oral; Animals; Biological Availability; Cell Line, | 2011 |
Qualitative LC-Q-TOF Analysis of Umbilical Cord Tissue via Data-Dependent Acquisition as an Indicator of In Utero Exposure to Toxic Adulterating Substances.
Topics: Analgesics, Opioid; Caffeine; Cocaine; Diphenhydramine; Drug Contamination; Female; Humans; Levamiso | 2022 |
Midwifery Management of a Birthing Person with Cervical Edema During Labor.
Topics: Diphenhydramine; Edema; Female; Humans; Ice; Labor, Obstetric; Midwifery; Pregnancy | 2022 |
Transient Fetal Tachycardia After Intravenous Diphenhydramine Administration.
Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Cesarean Section; Diphenhydramine; Female; F | 2017 |
Migraine Treatment in Pregnant Women Presenting to Acute Care: A Retrospective Observational Study.
Topics: Acetaminophen; Adult; Analgesics; Antiemetics; Diphenhydramine; Drug Therapy, Combination; Female; H | 2019 |
Successful mast-cell-targeted treatment of chronic dyspareunia, vaginitis, and dysfunctional uterine bleeding.
Topics: Administration, Topical; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Cromolyn Sodium; Diphen | 2019 |
Contribution of in utero drug exposure when interpreting hair results in young children.
Topics: Amitriptyline; Bromazepam; Cannabinoids; Diazepam; Diphenhydramine; Female; Forensic Toxicology; Hai | 2015 |
Prochlorperazine-Induced Hemidystonia Mimicking Acute Stroke.
Topics: Adult; Diphenhydramine; Dystonia; Emergency Medicine; Female; Humans; Hyperemesis Gravidarum; Infusi | 2015 |
Metoclopramide and diphenhydramine in the treatment of hyperemesis gravidarum: effectiveness and predictors of rehospitalisation.
Topics: Adolescent; Adult; Antiemetics; Cohort Studies; Diphenhydramine; Drug Therapy, Combination; Female; | 2009 |
Sleep complaints: Whenever possible, avoid the use of sleeping pills.
Topics: Acupuncture Therapy; Adult; Aged; Behavior Therapy; Benzodiazepines; Clinical Trials as Topic; Conge | 2008 |
Management of hepatic echinococcosis in pregnancy.
Topics: Adult; Albendazole; Cesarean Section; Diphenhydramine; Echinococcosis, Hepatic; Famotidine; Female; | 2010 |
Case report: massive blood transfusion in a patient with immunoglobulin a deficiency undergoing cesarean delivery.
Topics: Adrenal Cortex Hormones; Adult; Apgar Score; Blood Cell Count; Blood Transfusion; Cesarean Section; | 2010 |
Pemphigoid gestationis.
Topics: Adult; Autoimmune Diseases; Basement Membrane; Complement C3; Diphenhydramine; Eosinophils; Female; | 2010 |
Inhibition of decidual cell formation in the pseudopregnant rat by histamine antagonists.
Topics: Animals; Diphenhydramine; Ephedrine; Female; Histamine Antagonists; Humans; Hydatidiform Mole, Invas | 1952 |
[Medical therapy of radiation sickness and hyperemesis gravidarum].
Topics: Belladonna Alkaloids; Diphenhydramine; Female; Humans; Hyperemesis Gravidarum; Pregnancy; Radiation | 1959 |
[Experience with 4,4'-diacetoxy-diphenyl-pyridyl-2-methane in obstetrics].
Topics: Biphenyl Compounds; Catecholamines; Diphenhydramine; Female; Humans; Methane; Obstetrics; Pregnancy; | 1960 |
Treatment of leg cramps during pregnancy: use of diphenhydramine HCl.
Topics: Diphenhydramine; Female; Humans; Leg; Muscle Cramp; Pregnancy; Pregnancy Complications | 1960 |
DETERMINATION OF THE SENSITIVE PERIOD FOR THE INDUCTION OF DECIDUOMATA IN THE RAT BY DIFFERENT INDUCING PROCEDURES.
Topics: Bicarbonates; Borates; Bradykinin; Carbonates; Decidua; Diphenhydramine; Epinephrine; Female; Histam | 1963 |
[INVESTIGATION ON THE POSSIBLE RELATION OF FETAL INJURIES AND DRUGS. IV. RETROSPECTIVE STUDY ON DRUG CONSUMPTION AMONG MOTHERS WITH MALFORMED CHILDREN].
Topics: Abnormalities, Drug-Induced; Diphenhydramine; Down Syndrome; Fetal Diseases; Hip Dislocation; Hip Di | 1964 |
CONTROL OF PAIN IN CERTAIN PERIPHERAL VASCULAR DISORDERS.
Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Diphenhydramine; Drug Therapy; Foot Diseases; Ge | 1964 |
[FAINTING AND NAUSEA OF PREGNANCY. ITS THERAPY WITH A COMBINATION OF A NEW POORLY SOLUBLE SALT OF DIPHENHYDRAMINE, SCOPOLAMINE AND PYRIDOXINE].
Topics: Diphenhydramine; Female; Humans; Hyperemesis Gravidarum; Nausea; Pharmacology; Pregnancy; Pyridoxine | 1963 |
ARTERIAL CARBON DIOXIDE AND OXYGEN TENSIONS DURING SPINAL BLOCK.
Topics: Anesthesia, Conduction; Anesthesia, Obstetrical; Anesthesia, Spinal; Blood Gas Analysis; Carbon Diox | 1965 |
IDIOPATHIC JAUNDICE OF PREGNANCY--A CASE REPORT.
Topics: Diphenhydramine; Female; Jaundice; Pregnancy; Pregnancy Complications; Toxicology | 1965 |
Self-management and pregnancy--safe interventions for panic, phobia and other anxiety-disorders might include over-the-counter (OTC) 'SSRI' antihistamines such as diphenhydramine and chlorpheniramine.
Topics: Adult; Chlorpheniramine; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Nonprescription | 2005 |
Structural and functional comparison of mast cells in the pregnant versus nonpregnant human uterus.
Topics: Ambrosia; Antigens, Plant; Case-Control Studies; Cell Count; Cyclooxygenase Inhibitors; Diphenhydram | 2006 |
Exposure to alcohol-containing medications during pregnancy.
Topics: Adjuvants, Pharmaceutic; Diphenhydramine; Drug-Related Side Effects and Adverse Reactions; Ethanol; | 2006 |
[On cases of complications after administration of streptomycin].
Topics: Abortion, Veterinary; Animals; Cattle; Cattle Diseases; Diphenhydramine; Drug Hypersensitivity; Fema | 1966 |
Fetal distress during a maternal systemic allergic reaction.
Topics: Adult; Diphenhydramine; Ephedrine; Female; Fetal Distress; Fetal Heart; Fluid Therapy; Food Hypersen | 1984 |
Effects of histamine on the in vitro activity of the pregnant and non-pregnant uterus of the rat and guinea pig.
Topics: Animals; Cimetidine; Diphenhydramine; Estrus; Female; Guinea Pigs; Histamine; In Vitro Techniques; P | 1983 |
Deciduoma formation in uterus of genetically mast cell-deficient W/Wv mice.
Topics: Animals; Castration; Decidua; Diphenhydramine; Estradiol; Female; Mast Cells; Mice; Mice, Inbred Str | 1982 |
Trans-synaptic modulation of histamine H-1 receptor development in rat brain.
Topics: Animals; Animals, Newborn; Brain; Diphenhydramine; Female; Histamine; Hypothalamus; Pregnancy; Pyril | 1981 |
Effect of the antihistaminic drug Bromadryl on ex vivo platelet functions during gestation in rats.
Topics: Adenosine Diphosphate; Animals; Diphenhydramine; Dose-Response Relationship, Drug; Female; Histamine | 1994 |
Evaluation of the rat embryo culture system as a predictive test for human teratogens.
Topics: Abnormalities, Drug-Induced; Animals; Captopril; Diphenhydramine; DNA; Embryo, Mammalian; False Nega | 1994 |
Simultaneous analysis of diphenhydramine and a stable isotope analog (2H10)diphenhydramine using capillary gas chromatography with mass selective detection in biological fluids from chronically instrumented pregnant ewes.
Topics: Amniotic Fluid; Animals; Body Fluids; Chromatography, Gas; Diphenhydramine; Female; Fetal Blood; Pre | 1993 |
Transplacental and nonplacental clearances of diphenhydramine in the chronically instrumented pregnant sheep.
Topics: Animals; Dialysis; Diphenhydramine; Female; Fetus; Placenta; Pregnancy; Pregnancy, Animal; Protein B | 1993 |
Effect of the H1-antagonist bromadryl on mast cells in pregnant rats ex vivo.
Topics: Animals; Diphenhydramine; Female; Histamine H1 Antagonists; Mast Cells; Platelet Aggregation Inhibit | 1995 |
Droperidol and diphenhydramine in the management of hyperemesis gravidarum.
Topics: Adult; Delivery, Obstetric; Diphenhydramine; Droperidol; Female; Gestational Age; Humans; Hyperemesi | 1996 |
Hepatic first-pass uptake of diphenhydramine. A comparative study between fetal and adult sheep.
Topics: Age Factors; Animals; Body Weight; Diphenhydramine; Female; Fetus; Histamine H1 Antagonists; Liver; | 1996 |
Diphenhydramine overdose during pregnancy: lessons from the past.
Topics: Adult; Diphenhydramine; Drug Overdose; Female; Humans; Oxytocin; Pregnancy; Uterine Contraction | 1996 |
Estimation of transplacental and nonplacental diphenhydramine clearances in the fetal lamb: the impact of fetal first-pass hepatic drug uptake.
Topics: Animals; Blood Proteins; Diphenhydramine; Female; Liver; Maternal-Fetal Exchange; Placenta; Pregnanc | 1997 |
Simultaneous determination of diphenhydramine, its N-oxide metabolite and their deuterium-labeled analogues in ovine plasma and urine using liquid chromatography/electrospray tandem mass spectrometry.
Topics: Animals; Chromatography, High Pressure Liquid; Deuterium; Diphenhydramine; Female; Fetus; Histamine | 1998 |
Diphenhydramine disposition in the sheep maternal-placental-fetal unit: determinants of plasma drug concentrations in the mother and the fetus.
Topics: Animals; Blood Proteins; Diphenhydramine; Female; Fetus; Histamine H1 Antagonists; Humans; Maternal- | 1999 |
Diphenhydramine disposition in the sheep maternal-placental-fetal unit: gestational age, plasma drug protein binding, and umbilical blood flow effects on clearance.
Topics: Animals; Blood Proteins; Diphenhydramine; Embryonic and Fetal Development; Female; Fetus; Gestationa | 2000 |
Diphenhydramine toxicity in a newborn: a case report.
Topics: Depression, Chemical; Diphenhydramine; Female; Fetal Blood; Humans; Infant, Newborn; Maternal-Fetal | 2000 |
Hypersensitivity reactions following laminaria placement.
Topics: Abortion, Induced; Adult; Anti-Allergic Agents; Anti-Inflammatory Agents; Bronchodilator Agents; Can | 2000 |
[Diphenhydramine is useful in a parturient with hypersensitivity to local anesthetics to manage her delivery].
Topics: Adult; Analgesia, Obstetrical; Anaphylaxis; Anesthetics, Local; Diphenhydramine; Drug Hypersensitivi | 2002 |
Proestrus and metestrus rat uterus, a rapid and simple in vitro method for detecting histamine H2-receptor antagonism.
Topics: Animals; Cimetidine; Diphenhydramine; Estrus; Female; Histamine H2 Antagonists; In Vitro Techniques; | 1979 |
H1 and H2 histamine receptor participation in the brain control of prolactin secretion in lactating rats.
Topics: Animals; Diphenhydramine; Female; Histamine; Injections, Intraventricular; Lactation; Methylhistamin | 1977 |
[Study on the teratogenicity of benadryl in rats (author's transl)].
Topics: Abnormalities, Drug-Induced; Animals; Diphenhydramine; Female; Fetal Death; Pregnancy; Rats | 1977 |
Fetal and neonatal cardiopulmonary response to histamine.
Topics: Animals; Animals, Newborn; Aorta; Blood Pressure; Diphenhydramine; Ductus Arteriosus; Female; Fetus; | 1976 |
Physiological evidence consistent with the presence of a specific O2 carrier in the placenta.
Topics: Animals; Argon; Biological Transport; Diphenhydramine; Female; Nitrogen; Oxygen; Placenta; Pregnancy | 1975 |
Prenatal versus postnatal effects on offspring weight gain of rats exposed to diphenhydramine: a critical evaluation of fostering procedures in rats.
Topics: Animals; Animals, Suckling; Diphenhydramine; Female; Fetus; Maternal Behavior; Pregnancy; Prenatal E | 1991 |
Effects of prenatal diphenhydramine exposure on dopaminergic function in adult rats.
Topics: Animals; Apomorphine; Copulation; Corpus Striatum; Diphenhydramine; Dopamine; Female; Homovanillic A | 1991 |
Actions of vasoactive drugs on human placental vascular smooth muscle.
Topics: Arteries; Clonidine; Diphenhydramine; Dopamine; Female; Histamine; Humans; In Vitro Techniques; Musc | 1990 |
Effects of prenatal diphenhydramine administration on sexual behavior in rats.
Topics: Animals; Diphenhydramine; Ejaculation; Female; Male; Posture; Pregnancy; Prenatal Exposure Delayed E | 1989 |
Perinatal mortality due to interaction of diphenhydramine and temazepam.
Topics: Adult; Animals; Anti-Anxiety Agents; Diphenhydramine; Drug Synergism; Female; Fetal Death; Humans; P | 1985 |
Effects of diphenhydramine in the fetal lamb after maternal or fetal administration.
Topics: Animals; Brain; Carbon Dioxide; Diphenhydramine; Electroencephalography; Female; Fetus; Maternal-Fet | 1988 |
Anaphylaxis to human serum albumin.
Topics: Adult; Anaphylaxis; Diphenhydramine; Enzyme-Linked Immunosorbent Assay; Female; Humans; Injections, | 1988 |
Drug accumulation in lung fluid of the fetal lamb after maternal or fetal administration.
Topics: Animals; Body Fluids; Diphenhydramine; Female; Lung; Maternal-Fetal Exchange; Metoclopramide; Pregna | 1987 |
Determination of diphenhydramine in biological fluids by capillary gas chromatography using nitrogen-phosphorus detection. Application to placental transfer studies in pregnant sheep.
Topics: Animals; Chromatography, Gas; Diphenhydramine; Female; Fetus; Gas Chromatography-Mass Spectrometry; | 1986 |
Placental transfer of diphenhydramine in chronically instrumented pregnant sheep.
Topics: Animals; Diphenhydramine; Female; Fetus; Gestational Age; Kinetics; Maternal-Fetal Exchange; Oxygen; | 1986 |
Adaptation of fetal pulmonary blood flow to local infusion of tolazoline.
Topics: Animals; Blood Pressure; Cimetidine; Diphenhydramine; Female; Fetus; Heart Rate; Phentolamine; Pregn | 1986 |
Diphenhydramine.
Topics: Adult; Child; Diphenhydramine; Female; Humans; Pregnancy | 1986 |
Re: Pyloric stenosis and maternal antihistamine exposure at group health cooperative.
Topics: Diphenhydramine; Drug Combinations; Ephedrine; Female; Humans; Infant, Newborn; Maternal-Fetal Excha | 1985 |
Letter: Cleft palate and maternal diphenhydramine intake.
Topics: Animals; Cleft Lip; Cleft Palate; Cyclizine; Diphenhydramine; Female; Fetus; Histamine H1 Antagonist | 1974 |
[Mechanism of stimulating action of prostaglandin F2alpha on the contractile activity of the uterus].
Topics: Adrenergic alpha-Antagonists; Animals; Atropine; Diphenhydramine; Drug Synergism; Female; Muscle, Sm | 1973 |
[Methods of anesthesia in obstetric surgery].
Topics: Anesthesia, Obstetrical; Anesthetics; Anesthetics, Local; Antipsychotic Agents; Atropine; Diphenhydr | 1974 |
Embryotoxic effects of antihistamines.
Topics: Abnormalities, Drug-Induced; Abortion, Spontaneous; Animals; Body Weight; Chlorpheniramine; Diphenhy | 1968 |
Morphine-induced fetal malformations. II. Influence of histamine and diphenhydramine.
Topics: Abnormalities, Drug-Induced; Animals; Bone and Bones; Cryptorchidism; Diphenhydramine; Drug Synergis | 1971 |
The role of uterine inflammation in the inhibition of decidualization by intraluminal antihistamines.
Topics: Animals; Decidua; Dibenzylchlorethamine; Diphenhydramine; Endometrium; Female; Histamine H1 Antagoni | 1969 |
[Studies on the perfusion of the isolated human placenta with serotonin and the related substance].
Topics: Acetylcholine; Bradykinin; Diphenhydramine; Epinephrine; Ergotamine; Female; Histamine H1 Antagonist | 1972 |
Probable Benadryl withdrawal manifestations in a newborn infant.
Topics: Diphenhydramine; Female; Humans; Infant, Newborn; Infant, Newborn, Diseases; Maternal-Fetal Exchange | 1974 |
[Clinical contribution to the treatment of chornic obstructive bronchopneumopathies].
Topics: Adult; Aged; Aluminum Hydroxide; Aminophylline; Anti-Bacterial Agents; Chronic Disease; Diphenhydram | 1974 |
Chlorpromazine causing extrapyramidal dysfunction in newborn infant of psychotic mother.
Topics: Basal Ganglia Diseases; Chlorpromazine; Diphenhydramine; Female; Humans; Infant, Newborn; Infant, Ne | 1974 |
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compoun | 1972 |
Postpartum hypotension and erythema: an adverse reaction to soap enema.
Topics: Adult; Atropine; Bradycardia; Diphenhydramine; Enema; Erythema; Female; Hematocrit; Humans; Hypotens | 1973 |
Triploidy 69, XXX in a stillborn girl.
Topics: Adult; Asthma; Chromatids; Chromosome Aberrations; Chromosomes, Human, 1-3; Chromosomes, Human, 13-1 | 1973 |
Effect of certain drugs on perfused human placenta. X. Norepinephrine release by bradykinin.
Topics: Atropine; Bradykinin; Diphenhydramine; Drug Interactions; Female; Fluorescence; Humans; Muscle Contr | 1972 |
[Anesthesia for early artificial interruption of pregnancy].
Topics: Abortion, Induced; Anesthesia, Local; Anesthesia, Obstetrical; Anesthetics, Local; Diphenhydramine; | 1971 |
[A nonbarbituric hypnotic in obstetrics].
Topics: Diphenhydramine; Female; Humans; Labor, Obstetric; Maternal-Fetal Exchange; Methaqualone; Pregnancy | 1969 |
Reduced passage of carbon-14-dieldrin to the fetal rat by phenobarbital but not by eight other drugs or dieldrin.
Topics: Administration, Oral; Ammonium Chloride; Animals; Aspirin; Bicarbonates; Brain; Brain Chemistry; Car | 1971 |
Teratogenesis studies with diphenhydramine HCl.
Topics: Abnormalities, Drug-Induced; Analysis of Variance; Animals; Animals, Newborn; Corpus Luteum; Diphenh | 1971 |