diphenhydramine has been researched along with Poisoning in 33 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Poisoning: Used with drugs, chemicals, and industrial materials for human or animal poisoning, acute or chronic, whether the poisoning is accidental, occupational, suicidal, by medication error, or by environmental exposure.
| Excerpt | Relevance | Reference |
|---|---|---|
| "5 g diphenhydramine), so that a central anticholinergic syndrome due to an overdose with this drug could be assumed." | 8.79 | [An anticholinergic syndrome with hallucinatory psychosis after diphenhydramine poisoning]. ( Lang, K; Müller, S; Sigusch, H, 1995) |
| " A related drug, dimenhydrinate, is a less frequent cause of poisonings." | 7.73 | Diphenhydramine and dimenhydrinate poisoning: an evidence-based consensus guideline for out-of-hospital management. ( Booze, LL; Caravati, EM; Christianson, G; Chyka, PA; Erdman, AR; Keyes, DC; Manoguerra, AS; Nelson, LS; Olson, KR; Scharman, EJ; Troutman, WG; Wax, PM; Woolf, AD, 2006) |
| "Diphenhydramine poisoning is characterized most often by anticholinergic effects." | 7.68 | Massive diphenhydramine poisoning resulting in a wide-complex tachycardia: successful treatment with sodium bicarbonate. ( Clark, RF; Vance, MV, 1992) |
| "5 g diphenhydramine), so that a central anticholinergic syndrome due to an overdose with this drug could be assumed." | 4.79 | [An anticholinergic syndrome with hallucinatory psychosis after diphenhydramine poisoning]. ( Lang, K; Müller, S; Sigusch, H, 1995) |
| "Diphenhydramine is frequently misused and ingested recreationally for its antihistaminergic and antimuscarinic effects and is often involved in both serious and fatal poisonings, either in isolation or in combination with other xenobiotics." | 4.02 | Clinical and patient characteristics associated with severe outcome in diphenhydramine toxicity. ( Hendrickson, RG; Hughes, AR; Lin, A, 2021) |
| "A 13-month-old male who ingested 20 diphenhydramine (25 mg) tablets presented with seizures and ultimately progressed to status epilepticus and wide-complex tachycardia." | 3.77 | Survival after diphenhydramine ingestion with hemodialysis in a toddler. ( Hendrickson, RG; Horowitz, BZ; McKeown, NJ; West, PL, 2011) |
| "Diphenhydramine overdose in one of the frequent reported causes of acute poisoning." | 3.73 | QT interval prolongation in diphenhydramine toxicity. ( Aslam, AF; Aslam, AK; Khan, IA; Sacchi, TJ; Thakur, AC; Vasavada, BC, 2005) |
| " The practical use of the T(M) values as a support to distinguish between different metabolites in the HPLC-DAD analysis of intoxications is demonstrated with cases of poisoning with diphenhydramine, propafenone and methaqualone." | 3.69 | Shift of the high-performance liquid chromatographic retention times of metabolites in relation to the original drug on an RP8 column with acidic mobile phase. ( Herre, S; Pragst, F, 1997) |
| "Diphenhydramine poisoning is characterized most often by anticholinergic effects." | 3.68 | Massive diphenhydramine poisoning resulting in a wide-complex tachycardia: successful treatment with sodium bicarbonate. ( Clark, RF; Vance, MV, 1992) |
| "Diphenhydramine exposure was by ingestion for 581 (93." | 1.43 | Diphenhydramine exposure in dogs: 621 cases (2008-2013). ( Dorman, DC; Wismer, TA; Worth, AC, 2016) |
| " The interpretation of blood methadone concentrations alone or combined with other psychoactive drugs requires consideration of the subject's potential chronic use of and tolerance to the drug." | 1.34 | Methadone toxicity fatalities: a review of medical examiner cases in a large metropolitan area. ( Corey, TS; Hunsaker Iii, JC; Shields, LB; Stewart, D; Ward, MK, 2007) |
| "She presented with opisthotonus, ataxia, and bidirectional nystagmus." | 1.30 | Dystonic reaction associated with dextromethorphan ingestion in a toddler. ( Diekema, DS; Robertson, WO; Warden, CR, 1997) |
| "Of 233 charts coded as involving seizures, 191 occurred in humans and were available for analysis." | 1.29 | Seizures associated with poisoning and drug overdose. ( Benowitz, NL; Blanc, PD; Dyer, JE; Kearney, TE; Olson, KR, 1993) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (21.21) | 18.7374 |
| 1990's | 11 (33.33) | 18.2507 |
| 2000's | 7 (21.21) | 29.6817 |
| 2010's | 6 (18.18) | 24.3611 |
| 2020's | 2 (6.06) | 2.80 |
| Authors | Studies |
|---|---|
| Mehrpour, O | 1 |
| Hoyte, C | 1 |
| Delva-Clark, H | 1 |
| Al Masud, A | 1 |
| Biswas, A | 1 |
| Schimmel, J | 1 |
| Nakhaee, S | 1 |
| Goss, F | 1 |
| Hughes, AR | 1 |
| Lin, A | 1 |
| Hendrickson, RG | 2 |
| Worth, AC | 1 |
| Wismer, TA | 1 |
| Dorman, DC | 1 |
| Donkor, J | 1 |
| Armenian, P | 1 |
| Hartman, IN | 1 |
| Vohra, R | 1 |
| Gosselin, S | 1 |
| Hoegberg, LC | 1 |
| Hoffman, RS | 1 |
| Graudins, A | 1 |
| Stork, CM | 1 |
| Thomas, SH | 1 |
| Stellpflug, SJ | 1 |
| Hayes, BD | 1 |
| Levine, M | 1 |
| Morris, M | 1 |
| Nesbitt-Miller, A | 1 |
| Turgeon, AF | 1 |
| Bailey, B | 1 |
| Calello, DP | 1 |
| Chuang, R | 1 |
| Bania, TC | 1 |
| Mégarbane, B | 1 |
| Bhalla, A | 1 |
| Lavergne, V | 1 |
| Kimlin, EJ | 1 |
| Easter, JS | 1 |
| Ganetsky, M | 1 |
| McKeown, NJ | 1 |
| West, PL | 1 |
| Horowitz, BZ | 1 |
| Carstairs, SD | 1 |
| Schneir, AB | 1 |
| HUXTABLE, RF | 1 |
| LANDWIRTH, J | 1 |
| Englert, I | 1 |
| Thakur, AC | 1 |
| Aslam, AK | 1 |
| Aslam, AF | 1 |
| Vasavada, BC | 1 |
| Sacchi, TJ | 1 |
| Khan, IA | 1 |
| Scharman, EJ | 1 |
| Erdman, AR | 1 |
| Wax, PM | 1 |
| Chyka, PA | 1 |
| Caravati, EM | 1 |
| Nelson, LS | 1 |
| Manoguerra, AS | 1 |
| Christianson, G | 1 |
| Olson, KR | 2 |
| Woolf, AD | 1 |
| Keyes, DC | 1 |
| Booze, LL | 1 |
| Troutman, WG | 1 |
| Pragst, F | 3 |
| Herre, S | 2 |
| Bakdash, A | 1 |
| Shields, LB | 1 |
| Hunsaker Iii, JC | 1 |
| Corey, TS | 1 |
| Ward, MK | 1 |
| Stewart, D | 1 |
| Lang, K | 1 |
| Sigusch, H | 1 |
| Müller, S | 1 |
| Lindsay, CA | 1 |
| Williams, GD | 1 |
| Levin, DL | 1 |
| Viertel, A | 1 |
| Sachunsky, I | 1 |
| Wolf, G | 1 |
| Blaser, C | 1 |
| Nash, W | 1 |
| Kearney, TE | 1 |
| Dyer, JE | 1 |
| Benowitz, NL | 1 |
| Blanc, PD | 1 |
| Agarwal, SK | 1 |
| Tiwari, SC | 1 |
| Dash, SC | 1 |
| Savaloja, J | 1 |
| Warden, CR | 1 |
| Diekema, DS | 1 |
| Robertson, WO | 1 |
| Sporkert, F | 1 |
| Hestand, HE | 1 |
| Teske, DW | 1 |
| Clark, RF | 1 |
| Vance, MV | 1 |
| Cobbs, LW | 1 |
| Kuznetsova, NI | 1 |
| Jones, J | 1 |
| Dougherty, J | 1 |
| Cannon, L | 1 |
| Deutsch, DG | 1 |
| Bergert, RJ | 1 |
| Döring, G | 1 |
| Berg, S | 1 |
| Ruedy, J | 1 |
3 reviews available for diphenhydramine and Poisoning
| Article | Year |
|---|---|
Evidence-based recommendations on the use of intravenous lipid emulsion therapy in poisoning
Topics: Administration, Intravenous; Anesthetics; Animals; Calcium Channel Blockers; Cocaine; Diphenhydramin | 2016 |
[Current topics and problems in toxicology laboratories--7: Occurrence of poisoning due to 15 chemicals and introduction of analytical methods for diphenhydramine and SSRIs].
Topics: Acetaminophen; Benzodiazepines; Chromatography, High Pressure Liquid; Diphenhydramine; Gas Chromatog | 2010 |
[An anticholinergic syndrome with hallucinatory psychosis after diphenhydramine poisoning].
Topics: Adult; Combined Modality Therapy; Diagnosis, Differential; Diphenhydramine; Drug Overdose; Emergenci | 1995 |
30 other studies available for diphenhydramine and Poisoning
| Article | Year |
|---|---|
Classification of acute poisoning exposures with machine learning models derived from the National Poison Data System.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Aspirin; Benzodiazepines; Bupropion; Calc | 2022 |
Clinical and patient characteristics associated with severe outcome in diphenhydramine toxicity.
Topics: Adolescent; Adult; Aged; Aged, 80 and over; Child; Child, Preschool; Databases, Factual; Diphenhydra | 2021 |
Diphenhydramine exposure in dogs: 621 cases (2008-2013).
Topics: Animals; Anti-Allergic Agents; Diphenhydramine; Dog Diseases; Dogs; Female; Illinois; Male; Poison C | 2016 |
Analysis of Gastric Lavage Reported to a Statewide Poison Control System.
Topics: Acetaminophen; Adolescent; Adult; Aged; Aged, 80 and over; Anti-Inflammatory Agents, Non-Steroidal; | 2016 |
A 46-year-old woman with altered mental status and garbled speech.
Topics: Acetaminophen; Acetylcysteine; Diagnosis, Differential; Diphenhydramine; Electrocardiography; Female | 2009 |
Survival after diphenhydramine ingestion with hemodialysis in a toddler.
Topics: Diphenhydramine; Humans; Hypnotics and Sedatives; Infant; Injections, Intramuscular; Male; Midazolam | 2011 |
Images in clinical medicine. Opsoclonus due to diphenhydramine poisoning.
Topics: Diphenhydramine; Female; Humans; Ocular Motility Disorders; Poisoning; Young Adult | 2010 |
DIPHENHYDRAMINE POISONING TREATED BY EXCHANGE TRANSFUSION.
Topics: Diphenhydramine; Drug-Related Side Effects and Adverse Reactions; Electrocardiography; Electroenceph | 1963 |
[Diphenhydramin-overdose: anticholinergic symptoms, EEG-findings in the course and drug treatment of a gerontopsychiatric patient].
Topics: Aged; Brain; Cholinergic Antagonists; Dementia; Depressive Disorder; Diphenhydramine; Drug Therapy, | 2004 |
QT interval prolongation in diphenhydramine toxicity.
Topics: Adolescent; Diphenhydramine; Heart Conduction System; Histamine H1 Antagonists; Humans; Male; Poison | 2005 |
Diphenhydramine and dimenhydrinate poisoning: an evidence-based consensus guideline for out-of-hospital management.
Topics: Age Factors; Ambulatory Care; Dimenhydrinate; Diphenhydramine; Dose-Response Relationship, Drug; Eme | 2006 |
Poisonings with diphenhydramine--a survey of 68 clinical and 55 death cases.
Topics: Acetates; Adult; Aged, 80 and over; Benzhydryl Compounds; Child Abuse; Child, Preschool; Chromatogra | 2006 |
Methadone toxicity fatalities: a review of medical examiner cases in a large metropolitan area.
Topics: Adolescent; Adult; Antidepressive Agents; Benzodiazepines; Cannabinoids; Coroners and Medical Examin | 2007 |
Fatal adult respiratory distress syndrome after diphenhydramine toxicity in a child: a case report.
Topics: Child, Preschool; Diphenhydramine; Female; Humans; Poisoning; Respiratory Distress Syndrome | 1995 |
Treatment of diphenhydramine intoxication with haemoperfusion.
Topics: Adult; Diphenhydramine; Hemoperfusion; Humans; Male; Poisoning; Rhabdomyolysis | 1994 |
Treating diphenhydramine overdose.
Topics: Adolescent; Diphenhydramine; Female; Humans; Poisoning; Suicide, Attempted | 1994 |
Seizures associated with poisoning and drug overdose.
Topics: Adolescent; Adult; Age Factors; Aged; Anti-Arrhythmia Agents; Antidepressive Agents, Tricyclic; Caus | 1993 |
Spectrum of poisoning requiring haemodialysis in a tertiary care hospital in India.
Topics: Barbiturates; Copper; Copper Sulfate; Diphenhydramine; Drug Combinations; Ethylene Dibromide; Humans | 1993 |
Diphenhydramine hydrochloride helps symptoms of ciguatera fish poisoning.
Topics: Anti-Allergic Agents; Ciguatera Poisoning; Diphenhydramine; Humans; Micronesia; Poisoning | 1996 |
Shift of the high-performance liquid chromatographic retention times of metabolites in relation to the original drug on an RP8 column with acidic mobile phase.
Topics: Chromatography, High Pressure Liquid; Diphenhydramine; Humans; Methaqualone; Pharmaceutical Preparat | 1997 |
Dystonic reaction associated with dextromethorphan ingestion in a toddler.
Topics: Antidotes; Antitussive Agents; Ataxia; Child, Preschool; Dextromethorphan; Diphenhydramine; Dystonia | 1997 |
Use of headspace solid-phase microextraction (HS-SPME) in hair analysis for organic compounds.
Topics: Antidepressive Agents, Tricyclic; Cannabinoids; Chlormethiazole; Diphenhydramine; Gas Chromatography | 2000 |
Diphenhydramine hydrochloride intoxication.
Topics: Arrhythmias, Cardiac; Diphenhydramine; Humans; Infant; Male; Poisoning | 1977 |
Massive diphenhydramine poisoning resulting in a wide-complex tachycardia: successful treatment with sodium bicarbonate.
Topics: Adolescent; Alcohol Drinking; Bicarbonates; Blood Gas Analysis; Charcoal; Diphenhydramine; Electroca | 1992 |
Shakes and flashes in a relapsed alcoholic.
Topics: Alcoholic Intoxication; Chlordiazepoxide; Diphenhydramine; Drug Overdose; Hallucinations; Humans; Ma | 1992 |
[Thin-layer chromatography in the rapid diagnosis of acute drug poisoning in children].
Topics: Adolescent; Aminopyrine; Atropine; Barbiturates; Child; Child, Preschool; Chromatography, Thin Layer | 1985 |
Diphenhydramine-induced toxic psychosis.
Topics: Adult; Diphenhydramine; Humans; Male; Poisoning; Psychoses, Substance-Induced; Suicide, Attempted | 1986 |
Evaluation of a benchtop capillary gas chromatograph-mass spectrometer for clinical toxicology.
Topics: Diphenhydramine; Evaluation Studies as Topic; Gas Chromatography-Mass Spectrometry; Humans; Hypnotic | 1985 |
[The detection of bromoureide-poisoning in skeletal finds (author's transl)].
Topics: Adolescent; Adult; Bone and Bones; Bromides; Diphenhydramine; Female; Forensic Medicine; Germany, We | 1974 |
Acute drug poisoning in the adult.
Topics: Adult; Amphetamine; Antidepressive Agents; Cocaine; Diazepam; Diphenhydramine; Diuresis; Emergency S | 1973 |