Page last updated: 2024-10-26

diphenhydramine and Peripheral Nerve Diseases

diphenhydramine has been researched along with Peripheral Nerve Diseases in 5 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Research Excerpts

ExcerptRelevanceReference
"This Phase II trial was designed to evaluate the overall objective response rate, complete response rate, efficacy, and safety of weekly paclitaxel (Taxol) and carboplatin (Paraplatin) in the treatment of advanced urothelial carcinoma."5.11A phase II evaluation of weekly paclitaxel plus carboplatin in advanced urothelial cancer. ( Asmar, L; Dakhil, S; Friedland, DM; Gregurich, MA; Hollen, C, 2004)

Research

Studies (5)

TimeframeStudies, this research(%)All Research%
pre-19902 (40.00)18.7374
1990's0 (0.00)18.2507
2000's2 (40.00)29.6817
2010's1 (20.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Moulin, DE1
Morley-Forster, PK1
Pirani, Z1
Rohfritsch, C1
Stitt, L1
Ho, TW1
Backonja, M1
Ma, J1
Leibensperger, H1
Froman, S1
Polydefkis, M1
Friedland, DM1
Dakhil, S1
Hollen, C1
Gregurich, MA1
Asmar, L1
Constantinidis, K1
Blumstein, GI1
Kreithen, H1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
The Role of Intravenous (IV) Lidocaine in the Management of Chronic Neuropathic Pain of Peripheral Nerve Origin[NCT01669967]34 participants (Actual)Interventional2011-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trials

3 trials available for diphenhydramine and Peripheral Nerve Diseases

ArticleYear
Intravenous lidocaine in the management of chronic peripheral neuropathic pain: a randomized-controlled trial.
    Canadian journal of anaesthesia = Journal canadien d'anesthesie, 2019, Volume: 66, Issue:7

    Topics: Aged; Anesthetics, Local; Chronic Pain; Cross-Over Studies; Diabetic Neuropathies; Diphenhydramine;

2019
Efficient assessment of neuropathic pain drugs in patients with small fiber sensory neuropathies.
    Pain, 2009, Volume: 141, Issue:1-2

    Topics: Adolescent; Adult; Amines; Analgesics; Cross-Over Studies; Cyclohexanecarboxylic Acids; Diphenhydram

2009
A phase II evaluation of weekly paclitaxel plus carboplatin in advanced urothelial cancer.
    Cancer investigation, 2004, Volume: 22, Issue:3

    Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Antineoplastic Combined Chemotherapy Protocols; A

2004

Other Studies

2 other studies available for diphenhydramine and Peripheral Nerve Diseases

ArticleYear
Severe peripheral neuropathy after mandrax overdose.
    British medical journal, 1975, May-17, Volume: 2, Issue:5967

    Topics: Aged; Diphenhydramine; Drug Combinations; Humans; Male; Methaqualone; Peripheral Nervous System Dise

1975
Peripheral neuropathy following tetanus toxoid administration.
    JAMA, 1966, Nov-28, Volume: 198, Issue:9

    Topics: Adult; Diphenhydramine; Humans; Injections, Intramuscular; Male; Peripheral Nervous System Diseases;

1966