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diphenhydramine and Peptic Ulcer

diphenhydramine has been researched along with Peptic Ulcer in 16 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Peptic Ulcer: Ulcer that occurs in the regions of the GASTROINTESTINAL TRACT which come into contact with GASTRIC JUICE containing PEPSIN and GASTRIC ACID. It occurs when there are defects in the MUCOSA barrier. The common forms of peptic ulcers are associated with HELICOBACTER PYLORI and the consumption of nonsteroidal anti-inflammatory drugs (NSAIDS).

Research

Studies (16)

TimeframeStudies, this research(%)All Research%
pre-199015 (93.75)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (6.25)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
KAY, AW1
SCOTT, LD1
SMITH, WE1
FRIESEN, SR1
BARONOFSKY, ID1
WANGENSTEEN, OH1
CRANE, JT1
LINDSAY, S1
DAILEY, ME1
MOERSCH, RU1
RIVERS, AB1
MORLOCK, CG1
Hampton, DD1
Hale, LP1
STEVENS, RP1
ALSTED, G1
STEINBERG, N1
Kodama, M1
Ogawa, Y1
Ito, N1
Takeuchi, H1
Seikoh, R1
Tanaka, T1
Harada, M1
Kodama, O1
Ezaki, H1
Kushnir, VE1
Reĭngardt, BK1
Spivak, AM1
Chernin, VV1
Bystrov, VN1
Shanin, SS1
Shtanov, SA1
Kanishchev, PA1
Boedyreva, VD1
Winship, DH1
Ellison, EH1
Welch, RM1
Harrison, YE1
Burns, JJ1
Smoligovets, PV1

Other Studies

16 other studies available for diphenhydramine and Peptic Ulcer

ArticleYear
Observations on the use of benadryl in duodenal ulcer.
    Glasgow medical journal, 1947, Volume: 28, Issue:6

    Topics: Diphenhydramine; Duodenal Ulcer; Humans; Peptic Ulcer

1947
Benadryl fails to protect against the histamine-provoked ulcer.
    Proceedings of the Society for Experimental Biology and Medicine. Society for Experimental Biology and Medicine (New York, N.Y.), 1946, Volume: 63, Issue:1

    Topics: Amino Acids; Diphenhydramine; Drug Combinations; Ethers; Histamine; Histamine Agents; Peptic Ulcer;

1946
An attempt to prevent histamine-induced ulcers in guinea pigs with benadryl (beta dimethylamino-ethylbenzhydryl ether hydrochloride).
    The American journal of digestive diseases, 1947, Volume: 14, Issue:2

    Topics: Amino Acids; Diphenhydramine; Drug Combinations; Ether; Ethers; Guinea Pigs; Histamine; Peptic Ulcer

1947
Some results of the gastric secretory response of patients having duodenal ulcer noted during the administration of benadryl.
    Gastroenterology, 1946, Volume: 7

    Topics: Diphenhydramine; Duodenal Ulcer; Gastric Mucosa; Humans; Peptic Ulcer

1946
Mast cells are critical for protection against peptic ulcers induced by the NSAID piroxicam.
    PloS one, 2011, Volume: 6, Issue:8

    Topics: Animals; Anti-Inflammatory Agents, Non-Steroidal; Cell Proliferation; Cell Survival; Cyclooxygenase

2011
[Medical treatment of gastroduodenal ulcer with 2, 2-diphenyl-4-(diisopropylamino)butyramide methiodide (R 79)].
    Bruxelles medical, 1956, Apr-15, Volume: 36, Issue:16

    Topics: Amides; Biphenyl Compounds; Diphenhydramine; Parasympatholytics; Peptic Ulcer

1956
The effect of dimethylaminoethyl benzhydryl ether hydrochloride (amidryl) on gastric secretion in peptic ulcer patients.
    Acta medica Scandinavica. Supplementum, 1950, Volume: 239

    Topics: Digestion; Diphenhydramine; Ether; Ethers; Gastric Juice; Peptic Ulcer

1950
New anticholinergic drugs in peptic ulcer therapy; preliminary report on tropine benzohydryl (MK-02).
    The Review of gastroenterology, 1952, Volume: 19, Issue:5

    Topics: Choline; Cholinergic Antagonists; Diphenhydramine; Peptic Ulcer; Tropanes

1952
Inhibitory effects of histamine receptor antagonist on stress ulcer.
    Hiroshima journal of medical sciences, 1983, Volume: 32, Issue:3

    Topics: Animals; Cimetidine; Diphenhydramine; Gastric Mucosa; Histamine Antagonists; Histamine Release; Male

1983
[Use of dimedrol in the combined treatment of peptic ulcer patients].
    Vrachebnoe delo, 1983, Issue:4

    Topics: Adult; Aged; Chronic Disease; Diphenhydramine; Drug Evaluation; Drug Therapy, Combination; Female; H

1983
[Pathogenetic bases for the use of histamine and dimedrol in the overall treatment of recurrent peptic ulcer].
    Terapevticheskii arkhiv, 1981, Volume: 53, Issue:2

    Topics: Adult; Chronic Disease; Diphenhydramine; Drug Evaluation; Histamine; Humans; Middle Aged; Peptic Ulc

1981
[Electroanalgesia after operations on the abdominal organs].
    Vestnik khirurgii imeni I. I. Grekova, 1987, Volume: 139, Issue:8

    Topics: Analgesics; Cholecystitis; Diphenhydramine; Dipyrone; Electric Stimulation Therapy; Hemodynamics; Hu

1987
[Maximum histamine test for gastric secretion].
    Laboratornoe delo, 1971, Volume: 7

    Topics: Adolescent; Adult; Aged; Child; Child, Preschool; Diphenhydramine; Female; Gastric Juice; Gastric Mu

1971
Variability of gastric secretion in patients with and without the Zollinger-Ellison syndrome.
    Lancet (London, England), 1967, May-27, Volume: 1, Issue:7500

    Topics: Adolescent; Adult; Diagnosis, Differential; Diphenhydramine; Female; Gastric Acidity Determination;

1967
Implications of enzyme induction in drug toxicity studies.
    Toxicology and applied pharmacology, 1967, Volume: 10, Issue:2

    Topics: Animals; Antipyrine; Diphenhydramine; Dogs; Enzyme Induction; Female; Haplorhini; Liver; Male; Micro

1967
[Effect of dimedrol on the function of the pancreas, gallbladder and pyloric valve in patients with peptic ulcer and chronic gastritis].
    Vrachebnoe delo, 1967, Volume: 9

    Topics: Diphenhydramine; Gallbladder; Gastritis; Humans; Pancreas; Peptic Ulcer; Pylorus

1967