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diphenhydramine and Parkinson Disease, Secondary

diphenhydramine has been researched along with Parkinson Disease, Secondary in 6 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Parkinson Disease, Secondary: Conditions which feature clinical manifestations resembling primary Parkinson disease that are caused by a known or suspected condition. Examples include parkinsonism caused by vascular injury, drugs, trauma, toxin exposure, neoplasms, infections and degenerative or hereditary conditions. Clinical features may include bradykinesia, rigidity, parkinsonian gait, and masked facies. In general, tremor is less prominent in secondary parkinsonism than in the primary form. (From Joynt, Clinical Neurology, 1998, Ch38, pp39-42)

Research Excerpts

ExcerptRelevanceReference
"This report attempts to highlight that use of an antipsychotic and concurrent chronic use of methamphetamine can cause drug-induced parkinsonism."1.42Drug-induced parkinsonism following chronic methamphetamine use by a patient on haloperidol decanoate. ( Gedzior, JS; Matthew, BJ, 2015)

Research

Studies (6)

TimeframeStudies, this research(%)All Research%
pre-19905 (83.33)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's1 (16.67)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Matthew, BJ1
Gedzior, JS1
Hoffman, BF1
Carotti, A1
Tomassetti, G1
Lucciarini, L1
Barone, G1
Mugnai, A1
Klawans, HL1
Patni, SK1
Dandiya, PC2
Bhargava, LP1

Reviews

1 review available for diphenhydramine and Parkinson Disease, Secondary

ArticleYear
The pharmacology of parkinsonism (a review).
    Diseases of the nervous system, 1968, Volume: 29, Issue:12

    Topics: Acetylcholine; Animals; Atropa belladonna; Atropine; Central Nervous System; Chlorpromazine; Dextroa

1968

Other Studies

5 other studies available for diphenhydramine and Parkinson Disease, Secondary

ArticleYear
Drug-induced parkinsonism following chronic methamphetamine use by a patient on haloperidol decanoate.
    International journal of psychiatry in medicine, 2015, Volume: 50, Issue:4

    Topics: Adult; Amphetamine-Related Disorders; Diphenhydramine; Dose-Response Relationship, Drug; Drug Intera

2015
The diagnosis and treatment of neuroleptic-induced Parkinsonism.
    Hospital & community psychiatry, 1981, Volume: 32, Issue:2

    Topics: Antipsychotic Agents; Depression; Diagnosis, Differential; Diphenhydramine; Humans; Neurologic Exami

1981
[Trial use of L-dopa associated with a dopa-decarboxylase inhibitor in Parkinson's syndrome].
    La Clinica terapeutica, 1974, Jul-15, Volume: 70, Issue:1

    Topics: Animals; Aromatic Amino Acid Decarboxylase Inhibitors; Diphenhydramine; Drug Therapy, Combination; g

1974
The influence of monoamine oxidase inhibitors and some other antidepressants on the anti-parkinsonian activity of sub-effective doses of diphenylhydramine in rats and mice.
    Japanese journal of pharmacology, 1972, Volume: 22, Issue:3

    Topics: Animals; Antidepressive Agents; Catatonia; Diphenhydramine; Humans; Mice; Monoamine Oxidase Inhibito

1972
The antiparkinsonian activity of monoamine oxidase inhibitors and other agents in rats and mice.
    Archives internationales de pharmacodynamie et de therapie, 1968, Volume: 176, Issue:1

    Topics: Animals; Dextroamphetamine; Diphenhydramine; Imipramine; Iproniazid; Isocarboxazid; Mice; Monoamine

1968