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diphenhydramine and Pain, Intractable

diphenhydramine has been researched along with Pain, Intractable in 2 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Pain, Intractable: Persistent pain that is refractory to some or all forms of treatment.

Research Excerpts

ExcerptRelevanceReference
"We report three patients with advanced cancer pain refractory to adjuvants and oral, intravenous, and epidural opioids, who achieved sustained pain relief after the repeated administration of diphenhydramine."1.31Diphenhydramine as an analgesic adjuvant in refractory cancer pain. ( Fischberg, D; Gonzales, G; Khjainova, N; Kornick, C; Santiago-Palma, J, 2001)

Research

Studies (2)

TimeframeStudies, this research(%)All Research%
pre-19901 (50.00)18.7374
1990's0 (0.00)18.2507
2000's1 (50.00)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Santiago-Palma, J1
Fischberg, D1
Kornick, C1
Khjainova, N1
Gonzales, G1
Vetter, GW1

Other Studies

2 other studies available for diphenhydramine and Pain, Intractable

ArticleYear
Diphenhydramine as an analgesic adjuvant in refractory cancer pain.
    Journal of pain and symptom management, 2001, Volume: 22, Issue:2

    Topics: Aged; Child; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Neoplasms

2001
[Treatment possibilities of the non-specific (psychosomatic) pain syndrome of the locomotor system].
    Fortschritte der Medizin, 1978, Jan-26, Volume: 96, Issue:4

    Topics: Aspirin; Codeine; Diphenhydramine; Drug Combinations; Drug Evaluation; Humans; Meprobamate; Nicotini

1978