diphenhydramine has been researched along with Otitis Media with Effusion in 3 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Otitis Media with Effusion: Inflammation of the middle ear with a clear pale yellow-colored transudate.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Histamine, which has been found in middle ear effusions, is a potent pharmacological mediator released at an early stage of allergic reactions or general inflammatory process, increasing permeability of small blood vessels." | 7.68 | Histamine-induced mucociliary dysfunction and otitis media with effusion. ( Esaki, Y; Furuya, H; Nakai, Y; Ohashi, Y; Ohno, Y; Okamoto, H; Sugiura, Y, 1991) |
| "Histamine, which has been found in middle ear effusions, is a potent pharmacological mediator released at an early stage of allergic reactions or general inflammatory process, increasing permeability of small blood vessels." | 3.68 | Histamine-induced mucociliary dysfunction and otitis media with effusion. ( Esaki, Y; Furuya, H; Nakai, Y; Ohashi, Y; Ohno, Y; Okamoto, H; Sugiura, Y, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 1 (33.33) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jeong, HJ | 1 |
| Hong, SH | 1 |
| Kim, SC | 1 |
| Park, EJ | 1 |
| Jang, CH | 1 |
| Kim, KS | 1 |
| Kim, HM | 1 |
| O'Shea, JS | 1 |
| Langenbrunner, DJ | 1 |
| McCloskey, DE | 1 |
| Pezzullo, JC | 1 |
| Regan, JB | 1 |
| Esaki, Y | 1 |
| Ohashi, Y | 1 |
| Furuya, H | 1 |
| Sugiura, Y | 1 |
| Ohno, Y | 1 |
| Okamoto, H | 1 |
| Nakai, Y | 1 |
1 trial available for diphenhydramine and Otitis Media with Effusion
| Article | Year |
|---|---|
Childhood serous otitis media: fifteen months' observations of children untreated compared with those receiving an antihistamine-adrenergic combination.
Topics: Child; Child, Preschool; Clinical Trials as Topic; Diphenhydramine; Double-Blind Method; Drug Combin | 1982 |
2 other studies available for diphenhydramine and Otitis Media with Effusion
| Article | Year |
|---|---|
Effects of Allergina on the treatment of otitis media with effusions.
Topics: Adjuvants, Immunologic; Anti-Bacterial Agents; Anti-Inflammatory Agents, Non-Steroidal; Child; Child | 2002 |
Histamine-induced mucociliary dysfunction and otitis media with effusion.
Topics: Animals; Cilia; Cimetidine; Diphenhydramine; Ear, Middle; Eustachian Tube; Guinea Pigs; Histamine; M | 1991 |