diphenhydramine has been researched along with Nervous System Disorders in 8 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Metoclopramide is commonly used to treat vomiting caused by seasickness and acute gastroenteritis on cruise ships and serious adverse effects have not been reported from use at sea." | 7.80 | Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting. ( Dahl, E; Diskin, AL, 2014) |
| "A 4-year-old female blue and gold macaw (Ara ararauna) with a history of chronic vomiting was treated with metoclopramide hydrochloride." | 7.68 | Adverse drug reaction to metoclopramide hydrochloride in a macaw with proventricular dilatation syndrome. ( Massey, JG, 1993) |
| "Metoclopramide is commonly used to treat vomiting caused by seasickness and acute gastroenteritis on cruise ships and serious adverse effects have not been reported from use at sea." | 3.80 | Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting. ( Dahl, E; Diskin, AL, 2014) |
| "A 4-year-old female blue and gold macaw (Ara ararauna) with a history of chronic vomiting was treated with metoclopramide hydrochloride." | 3.68 | Adverse drug reaction to metoclopramide hydrochloride in a macaw with proventricular dilatation syndrome. ( Massey, JG, 1993) |
| " He developed a hypersensitivity reaction to cobra antivenin which responded to diphenhydramine." | 3.66 | Cobra envenomation: an uncommon emergency. ( Aprahamian, C; Darin, J; Horwitz, L; Stueven, H; Thompson, B, 1983) |
| "Fluphenazine was detected in serum or plasma from all 4 horses." | 1.33 | Adverse extrapyramidal effects in four horse given fluphenazine decanoate. ( Aravagiri, M; Arroyo, LG; Baird, JD; Kenney, DG; Maylin, GA; McGurrin, MK; Rodriguez-Palacios, A; Vengust, M, 2006) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 4 (50.00) | 18.7374 |
| 1990's | 1 (12.50) | 18.2507 |
| 2000's | 2 (25.00) | 29.6817 |
| 2010's | 1 (12.50) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Dahl, E | 1 |
| Diskin, AL | 1 |
| EVRARD, A | 1 |
| Baird, JD | 1 |
| Arroyo, LG | 1 |
| Vengust, M | 1 |
| McGurrin, MK | 1 |
| Rodriguez-Palacios, A | 1 |
| Kenney, DG | 1 |
| Aravagiri, M | 1 |
| Maylin, GA | 1 |
| Mota, MS | 1 |
| Natera, AH | 1 |
| Poussivert, EN | 1 |
| Valero, RS | 1 |
| Stueven, H | 1 |
| Aprahamian, C | 1 |
| Thompson, B | 1 |
| Horwitz, L | 1 |
| Darin, J | 1 |
| Massey, JG | 1 |
| Wiernik, PH | 1 |
| Schwartz, EL | 1 |
| Einzig, A | 1 |
| Strauman, JJ | 1 |
| Lipton, RB | 1 |
| Dutcher, JP | 1 |
| Trabert, W | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer[NCT02549534] | 29 participants (Actual) | Observational | 2015-09-30 | Completed | |||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
8 other studies available for diphenhydramine and Nervous System Disorders
| Article | Year |
|---|---|
Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting.
Topics: Adult; Antiemetics; Diphenhydramine; Dyskinesias; Female; Gastroenteritis; Humans; Injections, Intra | 2014 |
[Use of orphenadrine in neurology & psychiatry].
Topics: Diphenhydramine; Humans; Mental Disorders; Nervous System Diseases; Neurology; Orphenadrine; Psychia | 1959 |
Adverse extrapyramidal effects in four horse given fluphenazine decanoate.
Topics: Animals; Antipsychotic Agents; Behavior, Animal; Benztropine; Diphenhydramine; Extrapyramidal Tracts | 2006 |
[Anticholinergic syndrome. A case report].
Topics: Adult; Antiphospholipid Syndrome; Central Nervous System Diseases; Cholinergic Antagonists; Diphenhy | 2008 |
Cobra envenomation: an uncommon emergency.
Topics: Adult; Antivenins; Cobra Neurotoxin Proteins; Diphenhydramine; Elapid Venoms; Humans; Hypersensitivi | 1983 |
Adverse drug reaction to metoclopramide hydrochloride in a macaw with proventricular dilatation syndrome.
Topics: Animals; Bird Diseases; Dilatation, Pathologic; Diphenhydramine; Female; Metoclopramide; Nervous Sys | 1993 |
Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.
Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphenhydramine; Drug Admin | 1987 |
[Poisoning psychoses following suicide attempts with diphenhydramine].
Topics: Adult; Diagnosis, Differential; Diphenhydramine; Female; Hallucinations; Humans; Male; Nervous Syste | 1985 |