Page last updated: 2024-10-26

diphenhydramine and Neoplasms

diphenhydramine has been researched along with Neoplasms in 34 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Neoplasms: New abnormal growth of tissue. Malignant neoplasms show a greater degree of anaplasia and have the properties of invasion and metastasis, compared to benign neoplasms.

Research Excerpts

ExcerptRelevanceReference
"Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions."9.13A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008)
"289 consecutive cancer patients receiving cisplatin chemotherapy (much greater than 50 mg/m2) were randomised to receive one of the following intravenous antiemetic regimens: ondansetron 0."6.67Ondansetron + dexamethasone vs metoclopramide + dexamethasone + diphenhydramine in prevention of cisplatin-induced emesis. Italian Group For Antiemetic Research. ( , 1992)
"The topical gel known as "ABH gel," comprising lorazepam (Ativan(®)), diphenhydramine (Benadryl(®)), and haloperidol (Haldol(®)), is frequently used to treat nausea because of its perceived efficacy, relatively low cost, and ease of use in the home setting."5.19A randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea. ( Coyne, PJ; Dodson, PW; Fletcher, DS; Parker, GG; Smith, TJ; Wan, W, 2014)
"Acetaminophen and diphenhydramine are commonly used as pretransfusion medications to prevent transfusion reactions."5.13A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions. ( Case, LD; Cruz, JM; Hurd, DD; Kennedy, LD; Pomper, GJ, 2008)
" In addition, characterization of the UGT1A locus and genetic studies directed at understanding the role of bilirubin glucuronidation and the biochemical basis of the clinical symptoms found in unconjugated hyperbilirubinemia have uncovered the structural gene polymorphisms associated with Crigler-Najjar's and Gilbert's syndrome."4.80Human UDP-glucuronosyltransferases: metabolism, expression, and disease. ( Strassburg, CP; Tukey, RH, 2000)
"Temsirolimus (CCI-779) is a novel inhibitor of the mammalian target of rapamycin."2.75A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors. ( Fujisaka, Y; Horiike, A; Tamura, T; Yamada, Y; Yamamoto, N, 2010)
"Paclitaxel 135 mg/m2 was infused as a single dose over 1 hour or was divided into three doses infused over 1 hour on 3 consecutive days."2.68One-hour paclitaxel infusion schedules: a phase I/II comparative trial. ( Greco, FA; Hainsworth, JD, 1995)
"The present study was conducted to compare the pharmacokinetics and pharmacodynamics (PD) of paclitaxel between Phase I trials of 3- and 24-h infusions and to determine the most informative pharmacokinetic parameter to describe the PD."2.68Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion. ( Miyata, Y; Nakanomyo, H; Nishiwaki, Y; Ohtsu, T; Saijo, N; Sasaki, Y; Tamura, T, 1995)
"289 consecutive cancer patients receiving cisplatin chemotherapy (much greater than 50 mg/m2) were randomised to receive one of the following intravenous antiemetic regimens: ondansetron 0."2.67Ondansetron + dexamethasone vs metoclopramide + dexamethasone + diphenhydramine in prevention of cisplatin-induced emesis. Italian Group For Antiemetic Research. ( , 1992)
" Utilizing a 90-day BUD, lidocaine can be packaged separately from other magic mouthwash ingredients in individual dosage units and applied to the oral cavity using the swish-and-spit method."1.46Beyond-use dating of lidocaine alone and in two "magic mouthwash" preparations. ( Brown, SD; Huffman, J; Kirk, LM; Lewis, PO; Luu, Y; Ogle, A, 2017)
"We report three patients with advanced cancer pain refractory to adjuvants and oral, intravenous, and epidural opioids, who achieved sustained pain relief after the repeated administration of diphenhydramine."1.31Diphenhydramine as an analgesic adjuvant in refractory cancer pain. ( Fischberg, D; Gonzales, G; Khjainova, N; Kornick, C; Santiago-Palma, J, 2001)

Research

Studies (34)

TimeframeStudies, this research(%)All Research%
pre-19909 (26.47)18.7374
1990's12 (35.29)18.2507
2000's7 (20.59)29.6817
2010's6 (17.65)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Tukey, RH1
Strassburg, CP1
Hamed, MM1
Darwish, SS1
Herrmann, J1
Abadi, AH1
Engel, M1
Kirk, LM1
Brown, SD1
Luu, Y1
Ogle, A1
Huffman, J1
Lewis, PO1
Tempero, M1
Fletcher, DS1
Coyne, PJ1
Dodson, PW1
Parker, GG1
Wan, W1
Smith, TJ1
Kennedy, LD1
Case, LD1
Hurd, DD1
Cruz, JM1
Pomper, GJ1
Fujisaka, Y1
Yamada, Y1
Yamamoto, N1
Horiike, A1
Tamura, T2
Coulter, DW1
Walko, C1
Patel, J1
Moats-Staats, BM1
McFadden, A1
Smith, SV1
Khan, WA1
Bridges, AS1
Deal, AM1
Oesterheld, J1
Davis, IJ1
Blatt, J1
Thomas, RR1
Quinn, MG1
Schuler, B1
Grem, JL1
LATTANZI, A1
Laman, CA1
Silverstein, SB1
Rodgers, GM1
Bleicher, J1
Bhaskara, A1
Huyck, T1
Constantino, S1
Bardia, A1
Loprinzi, CL1
Silberstein, PT1
Plezia, PM2
Alberts, DS2
Kessler, J1
Aapro, MS1
Graham, V1
Surwit, EA1
Greco, FA2
Hainsworth, JD2
Siegall, CB1
Liggitt, D1
Chace, D1
Tepper, MA1
Fell, HP1
Purl, S1
Johnson, L1
Hanauer, S1
Schroeder, L1
Proeschel, C1
Alberts, J1
Bookman, MA1
Kloth, DD1
Kover, PE1
Smolinski, S1
Ozols, RF1
Dinndorf, PA1
McCabe, MA1
Frierdich, S1
Ohtsu, T1
Sasaki, Y1
Miyata, Y1
Nakanomyo, H1
Nishiwaki, Y1
Saijo, N1
Ballatori, E2
Roila, F2
Berto, P1
De Angelis, V1
Neri, C1
Olivieri, A1
Tonato, M2
Del Favero, A2
Turhal, NS1
Erdal, S1
Karacay, S1
Santiago-Palma, J1
Fischberg, D1
Kornick, C1
Khjainova, N1
Gonzales, G1
Adamski, P1
Kessler, JF1
Berens, PL1
Chase, JL1
Roe, DJ1
Basurto, C1
Bracarda, S1
Picciafuoco, M1
Culine, S1
Azab, M1
Pietri, F1
Ghosn, M1
Ben Amor, B1
Lupera, H1
Theodore, C1
Renaux, J1
Droz, JP1
Wiernik, PH2
Schwartz, EL2
Strauman, JJ2
Dutcher, JP2
Lipton, RB2
Paietta, E1
Einzig, A1
Furste, AB1
Davis, MP1
Gutterman, L1
Pritchard, JD1
Wheeler, W1
Enck, RE1
Sridhar, KS1
Donnelly, E1
Rhinehart, SN1
Dugan, WM1
Parashos, PJ1
Triplett, WC1
Minnick, DJ1
Fry, MW1
Macdonald, JM1

Clinical Trials (5)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Effect of Buffered Lidocaine With Epinephrine in Local Anesthesia During Subcutaneous Implantable Venous Access Devices Insertion: Double Blind Randomized Study.[NCT03628430]120 participants (Actual)Interventional2017-01-01Completed
An Open-label Randomized Clinical Trial to Compare the Toxicities and Efficacy of Pharmacokinetically-guided and BSA Fixed Dosing Strategy of Docetaxel and Paclitaxel in Chinese Non-small Cell Lung Cancer, Nasopharyngeal Carcinoma, and Breast Cancer Patie[NCT01891123]300 participants (Anticipated)Interventional2013-06-30Recruiting
A Clinical Experience Trial to Detect the Plasma Paclitaxel Drug Concentration in Chinese Non -Small Cell Lung Cancer (NSCLC) Patients Treated With a Paclitaxel Plus Carboplatin (TC) Regimens, and Explore Individualized Treatment Using Pharmacokinetically[NCT02737709]Phase 251 participants (Actual)Interventional2016-03-31Terminated (stopped due to The study have difficulty in recruiting subjectes)
Effectiveness and Quality of Life Analysis of Palonosetron Against Ondansetron Combined With Dexamethasone and Fosaprepitant in Prevention of Acute and Delayed Emesis Associated to Chemotherapy Moderate and Highly Emetogenic in Breast Cancer.[NCT03606369]Phase 2/Phase 3560 participants (Anticipated)Interventional2015-11-05Recruiting
Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer[NCT02549534]29 participants (Actual)Observational2015-09-30Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Reviews

3 reviews available for diphenhydramine and Neoplasms

ArticleYear
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000
Human UDP-glucuronosyltransferases: metabolism, expression, and disease.
    Annual review of pharmacology and toxicology, 2000, Volume: 40

    Topics: Autoimmunity; Chromosome Mapping; Glucuronides; Glucuronosyltransferase; Humans; Hyperbilirubinemia;

2000
Hypersensitivity and idiosyncratic reactions to oxaliplatin.
    Cancer, 2003, May-01, Volume: 97, Issue:9

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antiemetics; Antineoplastic Agents; Cim

2003
Hypersensitivity and idiosyncratic reactions to oxaliplatin.
    Cancer, 2003, May-01, Volume: 97, Issue:9

    Topics: Administration, Oral; Adult; Aged; Anti-Inflammatory Agents; Antiemetics; Antineoplastic Agents; Cim

2003
Combination antiemetics for cisplatin chemotherapy.
    Cancer, 1988, Apr-15, Volume: 61, Issue:8

    Topics: Antiemetics; Cisplatin; Dexamethasone; Diphenhydramine; Droperidol; Drug Evaluation; Drug Therapy, C

1988
Combination antiemetics for cisplatin chemotherapy.
    Cancer, 1988, Apr-15, Volume: 61, Issue:8

    Topics: Antiemetics; Cisplatin; Dexamethasone; Diphenhydramine; Droperidol; Drug Evaluation; Drug Therapy, C

1988

Trials

14 trials available for diphenhydramine and Neoplasms

ArticleYear
A randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea.
    Journal of pain and symptom management, 2014, Volume: 48, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antiemetics; Cross-Over Studies; Diphenhydramine;

2014
A randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea.
    Journal of pain and symptom management, 2014, Volume: 48, Issue:5

    Topics: Administration, Topical; Adolescent; Adult; Aged; Antiemetics; Cross-Over Studies; Diphenhydramine;

2014
A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions.
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Do

2008
A prospective, randomized, double-blind controlled trial of acetaminophen and diphenhydramine pretransfusion medication versus placebo for the prevention of transfusion reactions.
    Transfusion, 2008, Volume: 48, Issue:11

    Topics: Acetaminophen; Adolescent; Adult; Aged; Anti-Inflammatory Agents, Non-Steroidal; Diphenhydramine; Do

2008
A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:8

    Topics: Adult; Aged; Anti-Allergic Agents; Antineoplastic Agents; Area Under Curve; Carcinoma, Renal Cell; C

2010
A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors.
    Japanese journal of clinical oncology, 2010, Volume: 40, Issue:8

    Topics: Adult; Aged; Anti-Allergic Agents; Antineoplastic Agents; Area Under Curve; Carcinoma, Renal Cell; C

2010
Valproic acid reduces the tolerability of temsirolimus in children and adolescents with solid tumors.
    Anti-cancer drugs, 2013, Volume: 24, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Diphenhydramine

2013
Valproic acid reduces the tolerability of temsirolimus in children and adolescents with solid tumors.
    Anti-cancer drugs, 2013, Volume: 24, Issue:4

    Topics: Adolescent; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Diphenhydramine

2013
One-hour paclitaxel infusion schedules: a phase I/II comparative trial.
    Seminars in oncology, 1995, Volume: 22, Issue:3 Suppl 6

    Topics: Blood Cell Count; Breast Neoplasms; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration

1995
One-hour paclitaxel infusion schedules: a phase I/II comparative trial.
    Seminars in oncology, 1995, Volume: 22, Issue:3 Suppl 6

    Topics: Blood Cell Count; Breast Neoplasms; Cimetidine; Dexamethasone; Diphenhydramine; Drug Administration

1995
Paclitaxel administered by 1-hour infusion. Preliminary results of a phase I/II trial comparing two schedules.
    Cancer, 1994, Aug-15, Volume: 74, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cimetidine; Dexamethasone; Diphenhydr

1994
Paclitaxel administered by 1-hour infusion. Preliminary results of a phase I/II trial comparing two schedules.
    Cancer, 1994, Aug-15, Volume: 74, Issue:4

    Topics: Adult; Aged; Breast Neoplasms; Carcinoma, Non-Small-Cell Lung; Cimetidine; Dexamethasone; Diphenhydr

1994
Short-course intravenous prophylaxis for paclitaxel-related hypersensitivity reactions.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphen

1997
Short-course intravenous prophylaxis for paclitaxel-related hypersensitivity reactions.
    Annals of oncology : official journal of the European Society for Medical Oncology, 1997, Volume: 8, Issue:6

    Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphen

1997
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re

1995
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re

1995
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re

1995
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re

1995
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re

1995
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re

1995
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re

1995
Clinical pharmacokinetics and pharmacodynamics of paclitaxel: a 3-hour infusion versus a 24-hour infusion.
    Clinical cancer research : an official journal of the American Association for Cancer Research, 1995, Volume: 1, Issue:6

    Topics: Agranulocytosis; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Dose-Response Re

1995
Efficacy of treatment to relieve mucositis-induced discomfort.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2000, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Antineoplastic Agents; Diphenhydrami

2000
Efficacy of treatment to relieve mucositis-induced discomfort.
    Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2000, Volume: 8, Issue:1

    Topics: Adolescent; Adult; Aged; Aged, 80 and over; Anesthetics, Local; Antineoplastic Agents; Diphenhydrami

2000
Ondansetron + dexamethasone vs metoclopramide + dexamethasone + diphenhydramine in prevention of cisplatin-induced emesis. Italian Group For Antiemetic Research.
    Lancet (London, England), 1992, Jul-11, Volume: 340, Issue:8811

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antiemetics; Cisplatin; Clinical Protocols; De

1992
Ondansetron + dexamethasone vs metoclopramide + dexamethasone + diphenhydramine in prevention of cisplatin-induced emesis. Italian Group For Antiemetic Research.
    Lancet (London, England), 1992, Jul-11, Volume: 340, Issue:8811

    Topics: Administration, Oral; Adult; Aged; Aged, 80 and over; Antiemetics; Cisplatin; Clinical Protocols; De

1992
Randomized crossover comparison of high-dose intravenous metoclopramide versus a five-drug antiemetic regimen.
    Journal of pain and symptom management, 1990, Volume: 5, Issue:2

    Topics: Adult; Aged; Cisplatin; Dexamethasone; Diazepam; Diphenhydramine; Drug Therapy, Combination; Humans;

1990
Randomized crossover comparison of high-dose intravenous metoclopramide versus a five-drug antiemetic regimen.
    Journal of pain and symptom management, 1990, Volume: 5, Issue:2

    Topics: Adult; Aged; Cisplatin; Dexamethasone; Diazepam; Diphenhydramine; Drug Therapy, Combination; Humans;

1990
[A phase III trial comparing the antiemetic activity of tetracosactide with dexamethasone in combination with metoclopramide, diphenhydramine and clorazepate during chemotherapy including cisplatin].
    Bulletin du cancer, 1989, Volume: 76, Issue:6

    Topics: Adult; Aged; Cisplatin; Clinical Trials as Topic; Clorazepate Dipotassium; Cosyntropin; Dexamethason

1989
[A phase III trial comparing the antiemetic activity of tetracosactide with dexamethasone in combination with metoclopramide, diphenhydramine and clorazepate during chemotherapy including cisplatin].
    Bulletin du cancer, 1989, Volume: 76, Issue:6

    Topics: Adult; Aged; Cisplatin; Clinical Trials as Topic; Clorazepate Dipotassium; Cosyntropin; Dexamethason

1989
A pilot study comparing decadron (D)/ativan (A) versus reglan (R)/decadron (D)/benadryl (B) as antiemetic regimens.
    Progress in clinical and biological research, 1988, Volume: 278

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials

1988
A pilot study comparing decadron (D)/ativan (A) versus reglan (R)/decadron (D)/benadryl (B) as antiemetic regimens.
    Progress in clinical and biological research, 1988, Volume: 278

    Topics: Adult; Aged; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials

1988
The value of dexamethasone when added to combination drug therapy in the prevention of cisplatin-induced nausea and vomiting, evaluated by time-lapse video technology.
    Progress in clinical and biological research, 1986, Volume: 216

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Dexamethasone;

1986
The value of dexamethasone when added to combination drug therapy in the prevention of cisplatin-induced nausea and vomiting, evaluated by time-lapse video technology.
    Progress in clinical and biological research, 1986, Volume: 216

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Dexamethasone;

1986

Other Studies

17 other studies available for diphenhydramine and Neoplasms

ArticleYear
First Bispecific Inhibitors of the Epidermal Growth Factor Receptor Kinase and the NF-κB Activity As Novel Anticancer Agents.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; ErbB Receptors; Female;

2017
First Bispecific Inhibitors of the Epidermal Growth Factor Receptor Kinase and the NF-κB Activity As Novel Anticancer Agents.
    Journal of medicinal chemistry, 2017, 04-13, Volume: 60, Issue:7

    Topics: Animals; Antineoplastic Agents; Breast; Breast Neoplasms; Cell Line, Tumor; ErbB Receptors; Female;

2017
Beyond-use dating of lidocaine alone and in two "magic mouthwash" preparations.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2017, May-01, Volume: 74, Issue:9

    Topics: Administration, Oral; Aluminum Hydroxide; Analgesics; Antineoplastic Agents; Diphenhydramine; Drug C

2017
Beyond-use dating of lidocaine alone and in two "magic mouthwash" preparations.
    American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists, 2017, May-01, Volume: 74, Issue:9

    Topics: Administration, Oral; Aluminum Hydroxide; Analgesics; Antineoplastic Agents; Diphenhydramine; Drug C

2017
An Oncologist's Letter to Santa: Bring Me Drugs!
    Journal of the National Comprehensive Cancer Network : JNCCN, 2018, Volume: 16, Issue:12

    Topics: Administration, Intravenous; Antineoplastic Agents; Diphenhydramine; Drug Industry; Drugs, Generic;

2018
An Oncologist's Letter to Santa: Bring Me Drugs!
    Journal of the National Comprehensive Cancer Network : JNCCN, 2018, Volume: 16, Issue:12

    Topics: Administration, Intravenous; Antineoplastic Agents; Diphenhydramine; Drug Industry; Drugs, Generic;

2018
[Clinical effectiveness of a new analgesic tetracompound with synergic action].
    Gazzetta medica italiana, 1958, Volume: 117, Issue:1

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Diphenhydramine; Neoplasms; Pain Management; Par

1958
[Clinical effectiveness of a new analgesic tetracompound with synergic action].
    Gazzetta medica italiana, 1958, Volume: 117, Issue:1

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Diphenhydramine; Neoplasms; Pain Management; Par

1958
Parenteral iron therapy: a single institution's experience over a 5-year period.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2005, Volume: 3, Issue:6

    Topics: Acetaminophen; Anemia, Iron-Deficiency; Diphenhydramine; Female; Ferric Compounds; Ferric Oxide, Sac

2005
Parenteral iron therapy: a single institution's experience over a 5-year period.
    Journal of the National Comprehensive Cancer Network : JNCCN, 2005, Volume: 3, Issue:6

    Topics: Acetaminophen; Anemia, Iron-Deficiency; Diphenhydramine; Female; Ferric Compounds; Ferric Oxide, Sac

2005
Lorazepam, diphenhydramine, and haloperidol transdermal gel for rescue from chemotherapy-induced nausea/vomiting: results of two pilot trials.
    The journal of supportive oncology, 2008, Volume: 6, Issue:1

    Topics: Administration, Cutaneous; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Clini

2008
Lorazepam, diphenhydramine, and haloperidol transdermal gel for rescue from chemotherapy-induced nausea/vomiting: results of two pilot trials.
    The journal of supportive oncology, 2008, Volume: 6, Issue:1

    Topics: Administration, Cutaneous; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Clini

2008
Immediate termination of intractable vomiting induced by cisplatin combination chemotherapy using an intensive five-drug antiemetic regimen.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Diazepam; Dip

1984
Immediate termination of intractable vomiting induced by cisplatin combination chemotherapy using an intensive five-drug antiemetic regimen.
    Cancer treatment reports, 1984, Volume: 68, Issue:12

    Topics: Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Diazepam; Dip

1984
Prevention of immunotoxin-mediated vascular leak syndrome in rats with retention of antitumor activity.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Sep-27, Volume: 91, Issue:20

    Topics: Animals; Antibodies, Monoclonal; Blood Vessels; Cyclosporine; Dexamethasone; Diphenhydramine; Female

1994
Prevention of immunotoxin-mediated vascular leak syndrome in rats with retention of antitumor activity.
    Proceedings of the National Academy of Sciences of the United States of America, 1994, Sep-27, Volume: 91, Issue:20

    Topics: Animals; Antibodies, Monoclonal; Blood Vessels; Cyclosporine; Dexamethasone; Diphenhydramine; Female

1994
Diphenhydramine provides relief of cyclophosphamide-related symptoms.
    Oncology nursing forum, 1996, Volume: 23, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Cyclophosphamide; Diphenhydramine; Histamine H1 Antagonists; Huma

1996
Diphenhydramine provides relief of cyclophosphamide-related symptoms.
    Oncology nursing forum, 1996, Volume: 23, Issue:3

    Topics: Antineoplastic Agents, Alkylating; Cyclophosphamide; Diphenhydramine; Histamine H1 Antagonists; Huma

1996
Risk of abuse of diphenhydramine in children and adolescents with chronic illnesses.
    The Journal of pediatrics, 1998, Volume: 133, Issue:2

    Topics: Adolescent; Adult; Child; Chronic Disease; Diphenhydramine; Female; Hematologic Diseases; Histamine

1998
Risk of abuse of diphenhydramine in children and adolescents with chronic illnesses.
    The Journal of pediatrics, 1998, Volume: 133, Issue:2

    Topics: Adolescent; Adult; Child; Chronic Disease; Diphenhydramine; Female; Hematologic Diseases; Histamine

1998
Cost and cost-effectiveness analysis of ondansetron versus metoclopramide regimens: a hospital perspective from Italy.
    PharmacoEconomics, 1994, Volume: 5, Issue:3

    Topics: Chemotherapy, Adjuvant; Cisplatin; Costs and Cost Analysis; Dexamethasone; Diphenhydramine; Dose-Res

1994
Cost and cost-effectiveness analysis of ondansetron versus metoclopramide regimens: a hospital perspective from Italy.
    PharmacoEconomics, 1994, Volume: 5, Issue:3

    Topics: Chemotherapy, Adjuvant; Cisplatin; Costs and Cost Analysis; Dexamethasone; Diphenhydramine; Dose-Res

1994
Diphenhydramine as an analgesic adjuvant in refractory cancer pain.
    Journal of pain and symptom management, 2001, Volume: 22, Issue:2

    Topics: Aged; Child; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Neoplasms

2001
Diphenhydramine as an analgesic adjuvant in refractory cancer pain.
    Journal of pain and symptom management, 2001, Volume: 22, Issue:2

    Topics: Aged; Child; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Male; Middle Aged; Neoplasms

2001
Antiemetic suppositories.
    Oncology nursing forum, 1991, Volume: 18, Issue:3

    Topics: Administration, Rectal; Dexamethasone; Diphenhydramine; Drug Combinations; Humans; Metoclopramide; N

1991
Antiemetic suppositories.
    Oncology nursing forum, 1991, Volume: 18, Issue:3

    Topics: Administration, Rectal; Dexamethasone; Diphenhydramine; Drug Combinations; Humans; Metoclopramide; N

1991
A pilot study of metoclopramide, dexamethasone, diphenhydramine and lorazepam in prevention of nausea and vomiting in cisplatin-treated male patients.
    Oncology, 1990, Volume: 47, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Diphenhydramine; Drug Eval

1990
A pilot study of metoclopramide, dexamethasone, diphenhydramine and lorazepam in prevention of nausea and vomiting in cisplatin-treated male patients.
    Oncology, 1990, Volume: 47, Issue:5

    Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Diphenhydramine; Drug Eval

1990
Phase I clinical and pharmacokinetic study of taxol.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alkaloids; Alopecia; Cimetidine; Dexamethasone; Diph

1987
Phase I clinical and pharmacokinetic study of taxol.
    Cancer research, 1987, May-01, Volume: 47, Issue:9

    Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alkaloids; Alopecia; Cimetidine; Dexamethasone; Diph

1987
Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphenhydramine; Drug Admin

1987
Phase I trial of taxol given as a 24-hour infusion every 21 days: responses observed in metastatic melanoma.
    Journal of clinical oncology : official journal of the American Society of Clinical Oncology, 1987, Volume: 5, Issue:8

    Topics: Alkaloids; Antineoplastic Agents, Phytogenic; Cimetidine; Dexamethasone; Diphenhydramine; Drug Admin

1987
An effective hypnotic in malignant disease.
    The Practitioner, 1966, Volume: 197, Issue:181

    Topics: Diphenhydramine; Humans; Methaqualone; Neoplasms; Palliative Care; Tranquilizing Agents

1966
An effective hypnotic in malignant disease.
    The Practitioner, 1966, Volume: 197, Issue:181

    Topics: Diphenhydramine; Humans; Methaqualone; Neoplasms; Palliative Care; Tranquilizing Agents

1966