diphenhydramine has been researched along with Nausea in 67 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Nausea: An unpleasant sensation in the stomach usually accompanied by the urge to vomit. Common causes are early pregnancy, sea and motion sickness, emotional stress, intense pain, food poisoning, and various enteroviruses.
| Excerpt | Relevance | Reference |
|---|---|---|
| "In this study the potential of diphenhydramine in reducing respectively preventing vertigo and nausea induced by the ultra-high static magnetic field at 7 T was evaluated." | 9.17 | Efficacy of diphenhydramine in the prevention of vertigo and nausea at 7 T MRI. ( Adolf, D; Amthauer, H; Ricke, J; Speck, O; Thormann, M; Wollrab, A, 2013) |
| " Patients who presented to our emergency department with a primary or secondary chief complaint of nausea were randomized to one of the following 4 groups: (1) metoclopramide 10 mg+diphenhydramine 25 mg; (2) metoclopramide 10 mg+placebo; (3) metoclopramide 20 mg+diphenhydramine 25 mg; (4) metoclopramide 20 mg+placebo." | 9.14 | A randomized trial of diphenhydramine as prophylaxis against metoclopramide-induced akathisia in nauseated emergency department patients. ( Bender, B; Bijur, P; Davitt, M; Esses, D; Friedman, BW; Gallagher, EJ; Paternoster, J; Solorzano, C, 2009) |
| "Ondansetron appeared to be superior to metoclopramide-diphenhydramine in the control of emesis induced by chemotherapy regimens containing cisplatin." | 9.08 | Comparison of the efficacy and side-effects of ondansetron and metoclopramide-diphenhydramine administered to control nausea and vomiting in children treated with antineoplastic chemotherapy: a prospective randomized study. ( Atay, AA; Köseoglu, V; Kürekçi, AE; Ozcan, O; Sarici, U; Sorici, U, 1998) |
| "There was major control (0-1 episodes) of acute nausea-vomiting in all of the patients receiving the ondansetron combination antiemetic regimen, which was significantly better (P < 0." | 9.07 | Comparison of intermittent ondansetron versus continuous infusion metoclopramide used with standard combination antiemetics in control of acute nausea induced by cisplatin chemotherapy. ( Kilgore, JR; Navari, RM; Perrine, GM; Province, WS, 1993) |
| "The usefulness of alprazolam (minor tranquilizer) used in combination with metoclopramide plus methylprednisolone for the prevention and control of emesis induced by chemotherapies, including 5-day continuous intravenous infusion of cisplatin (25 mg/m2/day) for advanced lung cancer, was evaluated using a double-blind randomized crossover design." | 9.07 | Antiemetic efficacy of alprazolam in the combination of metoclopramide plus methylprednisolone. Double-blind randomized crossover study in patients with cisplatin-induced emesis. ( Mori, K; Saito, Y; Tominaga, K, 1993) |
| "To evaluate the efficacy and adverse events associated with the use of haloperidol for the treatment of nausea and vomiting in palliative care patients." | 8.91 | Haloperidol for the treatment of nausea and vomiting in palliative care patients. ( Dorman, S; Murray-Brown, F, 2015) |
| "To evaluate the efficacy of a combined therapy of prednisolone and alprazolam for controlling cisplatin-induced delayed emesis, a study involving 14 non-small cell lung cancer patients receiving cisplatin (80 mg/m2) was conducted." | 7.68 | [A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis]. ( Horio, Y; Iwahara, T; Minami, H; Sakai, S; Shibagaki, T; Shimokata, K; Watanabe, A, 1990) |
| " We have, therefore, carried out a multicenter, double-blind randomized trial comparing a combination of high-dose metoclopramide (MTC) (1 mg/kg x 4) and methylprednisolone (P) (treatment A) with a shorter but higher single-dose schedule of metoclopramide (3 mg/kg x 2) combined with dexamethasone (DEX) and diphenhydramine (DIP) to prevent extrapyramidal reactions (treatment B)." | 6.66 | Protection from nausea and vomiting in cisplatin-treated patients: high-dose metoclopramide combined with methylprednisolone versus metoclopramide combined with dexamethasone and diphenhydramine: a study of the Italian Oncology Group for Clinical Research ( Basurto, C; Bracarda, S; Di Costanzo, F; Donati, D; Malacarne, P; Monici, L; Patoia, L; Picciafuoco, M; Roila, F; Tonato, M, 1989) |
| "Diphenhydramine was administered intramuscularly 30 minutes before and 5 hours after chemotherapy." | 5.27 | [The prevention of CDDP-induced emesis with a combination regimen including metoclopramide, dexamethasone, droperidol and diphenhydramine]. ( Arihiro, T; Dozono, H; Morimoto, O; Ochiai, K; Sasaki, H; Takahashi, S; Terashima, Y; Tsuruoka, M; Yasuda, M; Yokoyama, S, 1987) |
| "The topical gel known as "ABH gel," comprising lorazepam (Ativan(®)), diphenhydramine (Benadryl(®)), and haloperidol (Haldol(®)), is frequently used to treat nausea because of its perceived efficacy, relatively low cost, and ease of use in the home setting." | 5.19 | A randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea. ( Coyne, PJ; Dodson, PW; Fletcher, DS; Parker, GG; Smith, TJ; Wan, W, 2014) |
| "In this study the potential of diphenhydramine in reducing respectively preventing vertigo and nausea induced by the ultra-high static magnetic field at 7 T was evaluated." | 5.17 | Efficacy of diphenhydramine in the prevention of vertigo and nausea at 7 T MRI. ( Adolf, D; Amthauer, H; Ricke, J; Speck, O; Thormann, M; Wollrab, A, 2013) |
| " Patients who presented to our emergency department with a primary or secondary chief complaint of nausea were randomized to one of the following 4 groups: (1) metoclopramide 10 mg+diphenhydramine 25 mg; (2) metoclopramide 10 mg+placebo; (3) metoclopramide 20 mg+diphenhydramine 25 mg; (4) metoclopramide 20 mg+placebo." | 5.14 | A randomized trial of diphenhydramine as prophylaxis against metoclopramide-induced akathisia in nauseated emergency department patients. ( Bender, B; Bijur, P; Davitt, M; Esses, D; Friedman, BW; Gallagher, EJ; Paternoster, J; Solorzano, C, 2009) |
| "The utility of intravenous prochlorperazine as an antiemetic agent and abortive therapy for headache may be limited by the frequent occurrence of akathisia, the distressing effects of which have been shown to disrupt patient care." | 5.09 | Diphenhydramine for the prevention of akathisia induced by prochlorperazine: a randomized, controlled trial. ( Drotts, DL; Vinson, DR, 2001) |
| "Intravenous antiemetic combinations containing a 5-HT3 receptor antagonist (like metoclopramide, ondansetron, or granisetron) with dexamethasone have become the standard therapy for the treatment of acute chemotherapy-induced vomiting." | 5.08 | Oral combination antiemetics in patients with small cell lung cancer receiving cisplatin or cyclophosphamide plus doxorubicin. ( Clark, RA; Cleri, LB; Gralla, RJ; Kris, MG; Pisters, KM; Tyson, LB, 1995) |
| "Both metoclopramide and prochlorperazine in combination with lorazepam and diphenhydramine offer good control of nausea and vomiting although the sedation and low risk for cardiac toxicity limit the regimen to an inpatient setting with close monitoring." | 5.08 | Randomized, double-blind comparison of a prochlorperazine-based versus a metoclopramide-based antiemetic regimen in patients undergoing autologous bone marrow transplantation. ( Gilbert, CJ; Ohly, KV; Peters, WP; Rosner, G, 1995) |
| "Infusion-related adverse events (IRAEs) such as nausea, vomiting, fever, chills, and thrombophlebitis that are associated with amphotericin B therapy often lead clinicians to prescribe a number of adjunctive pretreatment medications in an attempt to reduce the incidence and severity of these events." | 5.08 | Pretreatment regimens for adverse events related to infusion of amphotericin B. ( Cleary, JD; Goodwin, SD; Grasela, TH; Taylor, JW; Walawander, CA, 1995) |
| "Ondansetron appeared to be superior to metoclopramide-diphenhydramine in the control of emesis induced by chemotherapy regimens containing cisplatin." | 5.08 | Comparison of the efficacy and side-effects of ondansetron and metoclopramide-diphenhydramine administered to control nausea and vomiting in children treated with antineoplastic chemotherapy: a prospective randomized study. ( Atay, AA; Köseoglu, V; Kürekçi, AE; Ozcan, O; Sarici, U; Sorici, U, 1998) |
| " dexamethasone and oral metoclopramide) for delayed emesis, while they had received either i." | 5.07 | Cisplatin-induced delayed emesis: pattern and prognostic factors during three subsequent cycles. Italian Group for Antiemetic Research. ( , 1994) |
| "There was major control (0-1 episodes) of acute nausea-vomiting in all of the patients receiving the ondansetron combination antiemetic regimen, which was significantly better (P < 0." | 5.07 | Comparison of intermittent ondansetron versus continuous infusion metoclopramide used with standard combination antiemetics in control of acute nausea induced by cisplatin chemotherapy. ( Kilgore, JR; Navari, RM; Perrine, GM; Province, WS, 1993) |
| "The usefulness of alprazolam (minor tranquilizer) used in combination with metoclopramide plus methylprednisolone for the prevention and control of emesis induced by chemotherapies, including 5-day continuous intravenous infusion of cisplatin (25 mg/m2/day) for advanced lung cancer, was evaluated using a double-blind randomized crossover design." | 5.07 | Antiemetic efficacy of alprazolam in the combination of metoclopramide plus methylprednisolone. Double-blind randomized crossover study in patients with cisplatin-induced emesis. ( Mori, K; Saito, Y; Tominaga, K, 1993) |
| "This pilot randomized study compared MDL 72,222, a highly selective 5-HT3 receptor antagonist, with a high-dose metoclopramide regimen (HDM) for chemotherapy-induced nausea and vomiting." | 5.07 | Randomized comparison of the antiemetic efficacy of a serotonin type 3 receptor antagonist (MDL 72,222) with a high-dose metoclopramide regimen. ( Barrett, RJ; Hahne, WF; Heck, K; Homesley, HD; Lentz, SS; Lovelace, JV; McLees, B; Woodlief, L, 1993) |
| "A double-blind, randomized, crossover study was conducted to compare the efficacy and safety of high-dose dexamethasone (Protocol D) with a combination of dexamethasone, metoclopramide and diphenhydramine (Protocol DMD) in the management of chemotherapy-induced nausea and vomiting in cancer patients." | 5.06 | Antiemetic efficacy of high-dose dexamethasone: randomized, double-blind, crossover study with a combination of dexamethasone, metoclopramide and diphenhydramine. ( Ababtain, WA; Abdullah, KA; al-Idrissi, HY; Boukhary, HA; Ibrahim, EM; Macaulay, HM, 1988) |
| "To evaluate the efficacy and adverse events associated with the use of haloperidol for the treatment of nausea and vomiting in palliative care patients." | 4.91 | Haloperidol for the treatment of nausea and vomiting in palliative care patients. ( Dorman, S; Murray-Brown, F, 2015) |
| "A 46-year-old woman developed an anaphylactic reaction during percutaneous coronary intervention after she was pretreated with prednisone and diphenhydramine for a known allergy to iodine." | 3.71 | Potential anaphylactic shock with abciximab readministration. ( Hamel, D; Palisaitis, DA; Pharand, C, 2002) |
| "To evaluate the efficacy of a combined therapy of prednisolone and alprazolam for controlling cisplatin-induced delayed emesis, a study involving 14 non-small cell lung cancer patients receiving cisplatin (80 mg/m2) was conducted." | 3.68 | [A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis]. ( Horio, Y; Iwahara, T; Minami, H; Sakai, S; Shibagaki, T; Shimokata, K; Watanabe, A, 1990) |
| "Metoclopramide was administered as a 2-minute bolus infusion." | 2.77 | A trial of midazolam vs diphenhydramine in prophylaxis of metoclopramide-induced akathisia. ( Aydin, B; Erdur, B; Ergin, A; Kabay, B; Ozen, M; Parlak, I; Tura, P, 2012) |
| "Female patients with ovarian cancer are at high risk for emesis." | 2.67 | Ondansetron plus dexamethasone versus metoclopramide plus dexamethasone plus diphenhydramine in cisplatin-treated patients with ovarian cancer. Italian Group for Antiemetic Research. ( , 1994) |
| " Regimen B, employing a lower dosage of metoclopramide and steroids and using a more simple schedule of administration should be the preferred treatment." | 2.67 | Antiemetic activity of two different high doses and schedules of metoclopramide in dacarbazine-treated cancer patients. ( Basurto, C; Boschetti, E; Bracarda, S; Del Favero, A; Lupattelli, M; Picciafuoco, M; Roila, F; Sassi, M; Tonato, M, 1992) |
| "The present trial with high oral doses of metoclopramide was undertaken to (a) determine a well-tolerated dosage of oral metoclopramide; (b) measure the blood levels achieved with these oral doses; (c) determine the side effects of high doses; and (d) observe for antiemetic efficacy." | 2.66 | Dose-ranging antiemetic trial of high-dose oral metoclopramide. ( Clark, RA; Gralla, RJ; Kris, MG; Tyson, LB; Young, CW, 1989) |
| " We have, therefore, carried out a multicenter, double-blind randomized trial comparing a combination of high-dose metoclopramide (MTC) (1 mg/kg x 4) and methylprednisolone (P) (treatment A) with a shorter but higher single-dose schedule of metoclopramide (3 mg/kg x 2) combined with dexamethasone (DEX) and diphenhydramine (DIP) to prevent extrapyramidal reactions (treatment B)." | 2.66 | Protection from nausea and vomiting in cisplatin-treated patients: high-dose metoclopramide combined with methylprednisolone versus metoclopramide combined with dexamethasone and diphenhydramine: a study of the Italian Oncology Group for Clinical Research ( Basurto, C; Bracarda, S; Di Costanzo, F; Donati, D; Malacarne, P; Monici, L; Patoia, L; Picciafuoco, M; Roila, F; Tonato, M, 1989) |
| "Four consecutive trials were undertaken to study lorazepam at each of three dosage levels and diphenhydramine when used in combination with iv metoclopramide and dexamethasone in patients receiving cisplatin at 120 mg/m2." | 2.66 | Consecutive dose-finding trials adding lorazepam to the combination of metoclopramide plus dexamethasone: improved subjective effectiveness over the combination of diphenhydramine plus metoclopramide plus dexamethasone. ( Clark, RA; Fiore, JJ; Gralla, RJ; Groshen, S; Kelsen, DP; Kris, MG; Tyson, LB, 1985) |
| " Pyridoxine is considered safe for use during pregnancy, but its efficacy in treating nausea and vomiting has not been determined." | 2.37 | Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy. ( Leathem, AM, 1986) |
| "Flushing was the most common type of AE followed by nausea and hypertension." | 1.40 | Infusion technique of hematopoietic progenitor cells and related adverse events (CME). ( Bryant, SC; Gastineau, DA; Greiner, CW; Hogan, WJ; Jacob, EK; Lingineni, RK; Mohr, A; Mulay, SB; Padley, D, 2014) |
| " Adverse events with grade 3 or above hematologic toxicity were oligochromemia (M: 24." | 1.32 | [Paclitaxel plus carboplatin in ovarian cancer-comparison of adverse effects between monthly and weekly administration]. ( Fujii, T; Komatsu, M; Kumagai, M; Kusuda, T; Naitou, H; Shinkou, S; Takehara, K, 2004) |
| " infusion via an ambulatory infusion pump with patient-activated intermittent dosing (BAD pump) for prevention of acute and delayed nausea/vomiting in patients receiving high-dose chemotherapy (HDC) for peripheral blood progenitor cell (PBPC) mobilization (MOB) or prior to autologous PBPC rescue." | 1.30 | Safety and efficacy of a continuous infusion, patient controlled anti-emetic pump to facilitate outpatient administration of high-dose chemotherapy. ( Belt, R; Coon, J; Cord, M; Dix, S; Geller, R; Howard, S, 1999) |
| "Diphenhydramine was administered intramuscularly 30 minutes before and 5 hours after chemotherapy." | 1.27 | [The prevention of CDDP-induced emesis with a combination regimen including metoclopramide, dexamethasone, droperidol and diphenhydramine]. ( Arihiro, T; Dozono, H; Morimoto, O; Ochiai, K; Sasaki, H; Takahashi, S; Terashima, Y; Tsuruoka, M; Yasuda, M; Yokoyama, S, 1987) |
| " Before studying the efficacy of MCP as an antiemetic in children, we first had to establish the safe dose range." | 1.27 | Metoclopramide: dose-related toxicity and preliminary antiemetic studies in children receiving cancer chemotherapy. ( Allen, JC; Gralla, R; Kellick, M; Reilly, L; Young, C, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 21 (31.34) | 18.7374 |
| 1990's | 25 (37.31) | 18.2507 |
| 2000's | 11 (16.42) | 29.6817 |
| 2010's | 8 (11.94) | 24.3611 |
| 2020's | 2 (2.99) | 2.80 |
| Authors | Studies |
|---|---|
| Shirk, DV | 1 |
| Wendel, N | 1 |
| Williams, SD | 1 |
| Cardiel-Sam, H | 1 |
| Cohen, F | 1 |
| Friedman, BW | 2 |
| Weiß, M | 1 |
| Mulay, SB | 1 |
| Greiner, CW | 1 |
| Mohr, A | 1 |
| Bryant, SC | 1 |
| Lingineni, RK | 1 |
| Padley, D | 1 |
| Hogan, WJ | 1 |
| Gastineau, DA | 1 |
| Jacob, EK | 1 |
| Fletcher, DS | 1 |
| Coyne, PJ | 1 |
| Dodson, PW | 1 |
| Parker, GG | 1 |
| Wan, W | 1 |
| Smith, TJ | 1 |
| Yamamoto, K | 1 |
| Kato, N | 1 |
| Isogai, Y | 1 |
| Kuroda, T | 1 |
| Ishida, T | 1 |
| Yamatodani, A | 1 |
| Murray-Brown, F | 1 |
| Dorman, S | 1 |
| Bender, B | 1 |
| Davitt, M | 1 |
| Solorzano, C | 1 |
| Paternoster, J | 1 |
| Esses, D | 1 |
| Bijur, P | 1 |
| Gallagher, EJ | 1 |
| Kostic, MA | 1 |
| Gutierrez, FJ | 1 |
| Rieg, TS | 1 |
| Moore, TS | 1 |
| Gendron, RT | 1 |
| Erdur, B | 1 |
| Tura, P | 1 |
| Aydin, B | 1 |
| Ozen, M | 1 |
| Ergin, A | 1 |
| Parlak, I | 1 |
| Kabay, B | 1 |
| Thormann, M | 1 |
| Amthauer, H | 1 |
| Adolf, D | 1 |
| Wollrab, A | 1 |
| Ricke, J | 1 |
| Speck, O | 1 |
| WARRINGTON, WR | 2 |
| PASQUESI, TJ | 2 |
| KULASAVAGE, RJ | 2 |
| McCAWLEY, EL | 3 |
| DIDIER, EP | 1 |
| BARILA, TG | 1 |
| SLOCUM, HC | 1 |
| LINDGREN, VV | 1 |
| FREED, H | 1 |
| ROSENVASSER, EB | 1 |
| CARPANO, A | 1 |
| Kumagai, M | 1 |
| Fujii, T | 1 |
| Komatsu, M | 1 |
| Kusuda, T | 1 |
| Takehara, K | 1 |
| Shinkou, S | 1 |
| Naitou, H | 1 |
| Buss, MK | 1 |
| Arnold, RM | 1 |
| Swidan, SZ | 1 |
| Lake, AE | 1 |
| Saper, JR | 1 |
| Weschules, DJ | 1 |
| Lou, E | 1 |
| Abou-Zeid, N | 1 |
| Bleicher, J | 1 |
| Bhaskara, A | 1 |
| Huyck, T | 1 |
| Constantino, S | 1 |
| Bardia, A | 1 |
| Loprinzi, CL | 1 |
| Silberstein, PT | 1 |
| Glass, JR | 1 |
| Sproule, BA | 1 |
| Herrmann, N | 1 |
| Busto, UE | 1 |
| Ellis, PP | 1 |
| Schoenberger, M | 1 |
| Rendi, MA | 1 |
| McDermott, M | 1 |
| Goodwin, SD | 1 |
| Cleary, JD | 1 |
| Walawander, CA | 1 |
| Taylor, JW | 1 |
| Grasela, TH | 1 |
| Navari, RM | 2 |
| Province, WS | 1 |
| Perrine, GM | 1 |
| Kilgore, JR | 1 |
| Mori, K | 1 |
| Saito, Y | 1 |
| Tominaga, K | 1 |
| Homesley, HD | 1 |
| Hahne, WF | 1 |
| McLees, B | 1 |
| Heck, K | 1 |
| Barrett, RJ | 1 |
| Lentz, SS | 1 |
| Woodlief, L | 1 |
| Lovelace, JV | 1 |
| Cleri, LB | 1 |
| Kris, MG | 3 |
| Tyson, LB | 3 |
| Pisters, KM | 1 |
| Clark, RA | 3 |
| Gralla, RJ | 3 |
| Gilbert, CJ | 1 |
| Ohly, KV | 1 |
| Rosner, G | 1 |
| Peters, WP | 1 |
| Edmonson, JH | 1 |
| Ebbert, LP | 1 |
| Nascimento, AG | 1 |
| Jung, SH | 1 |
| McGaw, H | 1 |
| Gerstner, JB | 1 |
| Köseoglu, V | 1 |
| Kürekçi, AE | 1 |
| Sarici, U | 1 |
| Atay, AA | 1 |
| Ozcan, O | 1 |
| Sorici, U | 1 |
| Ballatori, E | 2 |
| Roila, F | 5 |
| Berto, P | 1 |
| De Angelis, V | 1 |
| Neri, C | 1 |
| Olivieri, A | 1 |
| Tonato, M | 5 |
| Del Favero, A | 4 |
| Dix, S | 1 |
| Cord, M | 1 |
| Howard, S | 1 |
| Coon, J | 1 |
| Belt, R | 1 |
| Geller, R | 1 |
| Higgins, BC | 1 |
| Vinson, DR | 1 |
| Drotts, DL | 1 |
| Uno, Y | 1 |
| Hirano, M | 1 |
| Murakami, N | 1 |
| Kikuchi, T | 1 |
| Nozawa, H | 1 |
| Okuda, T | 1 |
| Oya, J | 1 |
| Kikkawa, H | 1 |
| Pharand, C | 1 |
| Palisaitis, DA | 1 |
| Hamel, D | 1 |
| Tsavaris, NB | 1 |
| Warr, D | 1 |
| Wilan, A | 1 |
| Venner, P | 1 |
| Pater, J | 1 |
| Kaizer, L | 1 |
| Laberge, F | 1 |
| Latreille, J | 1 |
| Stewart, D | 1 |
| O'Connell, G | 1 |
| Osoba, D | 1 |
| Bracarda, S | 4 |
| Basurto, C | 4 |
| Sassi, M | 2 |
| Lupattelli, M | 2 |
| Picciafuoco, M | 4 |
| Boschetti, E | 2 |
| Edwards, JN | 1 |
| Herman, JA | 1 |
| Wallace, BK | 1 |
| Pavy, MD | 1 |
| Harrison-Pavy, J | 1 |
| Francom, M | 1 |
| Tsavaris, N | 1 |
| Zamanis, N | 1 |
| Zinelis, A | 1 |
| Tsoutsos, E | 1 |
| Mylonakis, N | 1 |
| Bacoyannis, C | 1 |
| Valilis, P | 1 |
| Sarafidou, M | 1 |
| Kosmidis, P | 1 |
| Adamski, P | 1 |
| Watanabe, A | 1 |
| Horio, Y | 1 |
| Minami, H | 1 |
| Shibagaki, T | 1 |
| Iwahara, T | 1 |
| Sakai, S | 1 |
| Shimokata, K | 1 |
| Young, CW | 1 |
| Donati, D | 1 |
| Malacarne, P | 1 |
| Monici, L | 1 |
| Di Costanzo, F | 1 |
| Patoia, L | 1 |
| Leathem, AM | 1 |
| Wiernik, PH | 1 |
| Schwartz, EL | 1 |
| Strauman, JJ | 1 |
| Dutcher, JP | 1 |
| Lipton, RB | 1 |
| Paietta, E | 1 |
| Unchern, S | 2 |
| Chumsawat, P | 1 |
| Sriwatanakul, K | 1 |
| Limsuwan, A | 1 |
| Sridhar, KS | 1 |
| Donnelly, E | 1 |
| al-Idrissi, HY | 1 |
| Ibrahim, EM | 1 |
| Abdullah, KA | 1 |
| Ababtain, WA | 1 |
| Boukhary, HA | 1 |
| Macaulay, HM | 1 |
| Grunberg, SM | 1 |
| Ehler, E | 1 |
| McDermed, JE | 1 |
| Akerley, WL | 1 |
| Dozono, H | 1 |
| Yasuda, M | 1 |
| Yokoyama, S | 1 |
| Takahashi, S | 1 |
| Ochiai, K | 1 |
| Tsuruoka, M | 1 |
| Morimoto, O | 1 |
| Sasaki, H | 1 |
| Arihiro, T | 1 |
| Terashima, Y | 1 |
| Rhinehart, SN | 1 |
| Dugan, WM | 1 |
| Parashos, PJ | 1 |
| Triplett, WC | 1 |
| Minnick, DJ | 1 |
| Fry, MW | 1 |
| Fiore, JJ | 1 |
| Kelsen, DP | 1 |
| Groshen, S | 1 |
| Allen, JC | 1 |
| Gralla, R | 1 |
| Reilly, L | 1 |
| Kellick, M | 1 |
| Young, C | 1 |
| Aschan, G | 1 |
| Norris, W | 1 |
| Nisbet, HI | 1 |
| Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
|---|---|---|---|---|---|---|---|
| Hydromorphone Versus Prochlorperazine + Diphenhydramine for Treatment of Acute Migraine. A Randomized, Emergency Department Based, Comparative Efficacy Study[NCT02389829] | Phase 4 | 127 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
| The Check Trial: A Comparison of Headache Treatment in the ED: Compazine Versus Ketamine. A Multi-Center, Randomized Double-Blind, Clinical Control Trial.[NCT02657031] | Phase 4 | 54 participants (Actual) | Interventional | 2016-03-17 | Completed | ||
| Intravenous Fluids in Benign Headaches Trail: A Randomized Single Blind Clinical Trial[NCT03185130] | Phase 4 | 58 participants (Actual) | Interventional | 2017-05-16 | Completed | ||
| A Randomized Double-blind Comparative Efficacy Trial of IV Acetaminophen Versus IV Ketorolac for Emergency Department Treatment of Generalized Headache[NCT03472872] | Phase 4 | 500 participants (Actual) | Interventional | 2017-09-05 | Terminated (stopped due to no longer recruiting or studying) | ||
| Early Detection of Taxane-Induced Neuropathy in Women With Breast Cancer[NCT02549534] | 29 participants (Actual) | Observational | 2015-09-30 | Completed | |||
| Effectiveness and Quality of Life Analysis of Palonosetron Against Ondansetron Combined With Dexamethasone and Fosaprepitant in Prevention of Acute and Delayed Emesis Associated to Chemotherapy Moderate and Highly Emetogenic in Breast Cancer.[NCT03606369] | Phase 2/Phase 3 | 560 participants (Anticipated) | Interventional | 2015-11-05 | Recruiting | ||
| [information is prepared from clinicaltrials.gov, extracted Sep-2024] | |||||||
Data collected by telephone. Patients were asked if they needed additional medication after discharge in order to reduce level of pain. This additional medication is considered rescue medication. (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydromorphone | 23 |
| Prochlorperazine | 4 |
Participants were asked to evaluate pain status since discharge. Participants who achieved total headache freedom for at least 1 hour are considered to achieve short term headache relief. (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydromorphone | 16 |
| Prochlorperazine | 29 |
"Participants were asked to make evaluation of pain status since discharge. Those achieving headache level mild or none for 1 hour are considered to achieve short term headache relief." (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydromorphone | 33 |
| Prochlorperazine | 53 |
"Sustained headache relief is defined as achieving a headache level of mild or none within two hours and maintaining a level of mild or none for 48 hours, without use of addition medication. Patient self-evaluated pain level is solicited every half hour for two hours in the Emergency Department and then by telephone 48 hours after medication administration." (NCT02389829)
Timeframe: up to 2 hours in Emergency Department, 48 hours after discharge from Emergency Department
| Intervention | Participants (Count of Participants) |
|---|---|
| Hydromorphone | 20 |
| Prochlorperazine | 37 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum anxiety. A change of 0 mm corresponds to no change in anxiety level, and a negative value indicates worsening of the anxiety after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 33.7 |
| Study Arm | 21.2 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. Positive values represent a reduction in headache severity. The maximum possible change in VAS score is 100 mm, representing the complete relief of a maximally severe headache. A change of 0 mm corresponds to no change in headache severity, and a negative value indicates worsening of the headache after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 63.5 |
| Study Arm | 43.5 |
Reduction in 100 mm Visual Analog Scale (VAS) Score. The maximum possible change in VAS score is 100 mm, representing the complete relief of maximum nausea. A change of 0 mm corresponds to no change in nausea level, and a negative value indicates worsening of the nausea after the medication. (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | mm (Mean) |
|---|---|
| Control Arm | 38.9 |
| Study Arm | 22.9 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 2 |
| Study Arm | 3 |
Yes/No (NCT02657031)
Timeframe: 0-60 minutes
| Intervention | participants (Number) |
|---|---|
| Control Arm | 3 |
| Study Arm | 3 |
3 reviews available for diphenhydramine and Nausea
| Article | Year |
|---|---|
Haloperidol for the treatment of nausea and vomiting in palliative care patients.
Topics: Antiemetics; Diphenhydramine; Gels; Haloperidol; Humans; Lorazepam; Nausea; Palliative Care; Randomi | 2015 |
Safety and efficacy of antiemetics used to treat nausea and vomiting in pregnancy.
Topics: Antiemetics; Antipsychotic Agents; Dicyclomine; Diphenhydramine; Doxylamine; Drug Combinations; Fema | 1986 |
Combination antiemetics for cisplatin chemotherapy.
Topics: Antiemetics; Cisplatin; Dexamethasone; Diphenhydramine; Droperidol; Drug Evaluation; Drug Therapy, C | 1988 |
32 trials available for diphenhydramine and Nausea
| Article | Year |
|---|---|
A randomized study of IV prochlorperazine plus diphenhydramine versus IV hydromorphone for migraine-associated symptoms: A post hoc analysis.
Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Antiemetics; Diphenhydramine; Double-Blind M | 2021 |
A randomized trial of the effectiveness of topical "ABH Gel" (Ativan(®), Benadryl(®), Haldol(®)) vs. placebo in cancer patients with nausea.
Topics: Administration, Topical; Adolescent; Adult; Aged; Antiemetics; Cross-Over Studies; Diphenhydramine; | 2014 |
A randomized trial of diphenhydramine as prophylaxis against metoclopramide-induced akathisia in nauseated emergency department patients.
Topics: Adult; Aged; Akathisia, Drug-Induced; Antiemetics; Diphenhydramine; Dopamine Antagonists; Double-Bli | 2009 |
A prospective, randomized trial of intravenous prochlorperazine versus subcutaneous sumatriptan in acute migraine therapy in the emergency department.
Topics: Adult; Akathisia, Drug-Induced; Analgesics; Conscious Sedation; Diphenhydramine; Double-Blind Method | 2010 |
A prospective, randomized trial of intravenous prochlorperazine versus subcutaneous sumatriptan in acute migraine therapy in the emergency department.
Topics: Adult; Akathisia, Drug-Induced; Analgesics; Conscious Sedation; Diphenhydramine; Double-Blind Method | 2010 |
A prospective, randomized trial of intravenous prochlorperazine versus subcutaneous sumatriptan in acute migraine therapy in the emergency department.
Topics: Adult; Akathisia, Drug-Induced; Analgesics; Conscious Sedation; Diphenhydramine; Double-Blind Method | 2010 |
A prospective, randomized trial of intravenous prochlorperazine versus subcutaneous sumatriptan in acute migraine therapy in the emergency department.
Topics: Adult; Akathisia, Drug-Induced; Analgesics; Conscious Sedation; Diphenhydramine; Double-Blind Method | 2010 |
A trial of midazolam vs diphenhydramine in prophylaxis of metoclopramide-induced akathisia.
Topics: Adult; Akathisia, Drug-Induced; Antiemetics; Diphenhydramine; Double-Blind Method; Female; Humans; H | 2012 |
Efficacy of diphenhydramine in the prevention of vertigo and nausea at 7 T MRI.
Topics: Adult; Diphenhydramine; Dose-Response Relationship, Drug; Double-Blind Method; Female; Humans; Hypno | 2013 |
Effects of 2-week treatment with temazepam and diphenhydramine in elderly insomniacs: a randomized, placebo-controlled trial.
Topics: Aged; Aged, 80 and over; Cross-Over Studies; Diphenhydramine; Dizziness; Dose-Response Relationship, | 2008 |
Pretreatment regimens for adverse events related to infusion of amphotericin B.
Topics: Acetaminophen; Adrenal Cortex Hormones; Amphotericin B; Diphenhydramine; Fever; Headache; Heparin; H | 1995 |
Cisplatin-induced delayed emesis: pattern and prognostic factors during three subsequent cycles. Italian Group for Antiemetic Research.
Topics: Acute Disease; Chi-Square Distribution; Cisplatin; Dexamethasone; Diphenhydramine; Drug Therapy, Com | 1994 |
Ondansetron plus dexamethasone versus metoclopramide plus dexamethasone plus diphenhydramine in cisplatin-treated patients with ovarian cancer. Italian Group for Antiemetic Research.
Topics: Adult; Aged; Aged, 80 and over; Cisplatin; Dexamethasone; Diphenhydramine; Drug Combinations; Drug T | 1994 |
Comparison of intermittent ondansetron versus continuous infusion metoclopramide used with standard combination antiemetics in control of acute nausea induced by cisplatin chemotherapy.
Topics: Adult; Aged; Antiemetics; Cisplatin; Costs and Cost Analysis; Dexamethasone; Diphenhydramine; Drug A | 1993 |
Antiemetic efficacy of alprazolam in the combination of metoclopramide plus methylprednisolone. Double-blind randomized crossover study in patients with cisplatin-induced emesis.
Topics: Adult; Aged; Alprazolam; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non | 1993 |
Randomized comparison of the antiemetic efficacy of a serotonin type 3 receptor antagonist (MDL 72,222) with a high-dose metoclopramide regimen.
Topics: Adult; Aged; Antiemetics; Cisplatin; Diphenhydramine; Drug Therapy, Combination; Female; Genital Neo | 1993 |
Oral combination antiemetics in patients with small cell lung cancer receiving cisplatin or cyclophosphamide plus doxorubicin.
Topics: Administration, Oral; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carcinoma, Non-Sm | 1995 |
Randomized, double-blind comparison of a prochlorperazine-based versus a metoclopramide-based antiemetic regimen in patients undergoing autologous bone marrow transplantation.
Topics: Adult; Antiemetics; Antineoplastic Agents; Antineoplastic Agents, Alkylating; Antineoplastic Combine | 1995 |
Phase II study of docetaxel in advanced soft tissue sarcomas.
Topics: Adult; Aged; Alopecia; Anorexia; Antiemetics; Antineoplastic Agents, Phytogenic; Cause of Death; Dex | 1996 |
Comparison of the efficacy and side-effects of ondansetron and metoclopramide-diphenhydramine administered to control nausea and vomiting in children treated with antineoplastic chemotherapy: a prospective randomized study.
Topics: Antiemetics; Antineoplastic Agents; Child; Diphenhydramine; Drug Therapy, Combination; Female; Human | 1998 |
Diphenhydramine for the prevention of akathisia induced by prochlorperazine: a randomized, controlled trial.
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antiemetics; Conscious Sedation; Diphenhydramine; Double | 2001 |
[Weekly administration of low-dose paclitaxel for advanced or metastatic breast cancer].
Topics: Aged; Alopecia; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Dexamethasone; Diphenhydramine; | 2002 |
A randomised, double-blind comparison of granisetron with high-dose metoclopramide, dexamethasone and diphenhydramine for cisplatin-induced emesis. An NCI Canada Clinical Trials Group Phase III Trial.
Topics: Antiemetics; Cisplatin; Dexamethasone; Diphenhydramine; Double-Blind Method; Drug Therapy, Combinati | 1992 |
Antiemetic activity of two different high doses and schedules of metoclopramide in dacarbazine-treated cancer patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Dacarbazine; Dexamethasone; Diphenhydramine; Double- | 1992 |
Double-blind crossover trial of single vs. divided dose of metoclopramide in a combined regimen for treatment of cisplatin-induced emesis.
Topics: Cisplatin; Dexamethasone; Diphenhydramine; Double-Blind Method; Drug Administration Schedule; Drug T | 1991 |
Comparison of patient-controlled and nurse-controlled antiemetic therapy in patients receiving chemotherapy.
Topics: Adult; Aged; Aged, 80 and over; Analgesia, Patient-Controlled; Antineoplastic Agents; Diphenhydramin | 1991 |
Diphenhydramine for nausea and vomiting related to cancer chemotherapy with cisplatin.
Topics: Adult; Aged; Antiemetics; Cisplatin; Diphenhydramine; Drug Therapy, Combination; Female; Humans; Mal | 1991 |
Comparison of intermittent versus continuous infusion metoclopramide in control of acute nausea induced by cisplatin chemotherapy.
Topics: Carcinoma, Non-Small-Cell Lung; Carcinoma, Small Cell; Cisplatin; Dexamethasone; Diphenhydramine; Dr | 1989 |
Dose-ranging antiemetic trial of high-dose oral metoclopramide.
Topics: Administration, Oral; Adult; Antineoplastic Agents; Clinical Trials as Topic; Diphenhydramine; Drug | 1989 |
Protection from nausea and vomiting in cisplatin-treated patients: high-dose metoclopramide combined with methylprednisolone versus metoclopramide combined with dexamethasone and diphenhydramine: a study of the Italian Oncology Group for Clinical Research
Topics: Age Factors; Antiemetics; Cisplatin; Dexamethasone; Diphenhydramine; Drug Administration Schedule; D | 1989 |
Antiemetic efficacy of high-dose dexamethasone: randomized, double-blind, crossover study with a combination of dexamethasone, metoclopramide and diphenhydramine.
Topics: Adolescent; Adult; Aged; Antineoplastic Agents; Clinical Trials as Topic; Dexamethasone; Diphenhydra | 1988 |
The value of dexamethasone when added to combination drug therapy in the prevention of cisplatin-induced nausea and vomiting, evaluated by time-lapse video technology.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Clinical Trials as Topic; Dexamethasone; | 1986 |
Consecutive dose-finding trials adding lorazepam to the combination of metoclopramide plus dexamethasone: improved subjective effectiveness over the combination of diphenhydramine plus metoclopramide plus dexamethasone.
Topics: Adult; Aged; Antineoplastic Combined Chemotherapy Protocols; Anxiety; Cisplatin; Clinical Trials as | 1985 |
Habituation to repeated rotatory stimuli (cupulometry) and the effect of antinausea drugs and alcohol on the results.
Topics: Aerospace Medicine; Alcoholic Intoxication; Chlorpheniramine; Clinical Trials as Topic; Dimenhydrina | 1967 |
Oral premedication: a study of the sedative effects of mandrax.
Topics: Adult; Blood Pressure; Clinical Trials as Topic; Diphenhydramine; Female; Genital Diseases, Female; | 1966 |
32 other studies available for diphenhydramine and Nausea
| Article | Year |
|---|---|
Topics: Angioedema; Antidepressive Agents; Anxiety; Aripiprazole; Black or African American; Child; Diphenhy | 2021 |
[Magnetic resonance imaging with protective medication--low-dose diphenhydramine can reduce dizziness].
Topics: Diphenhydramine; Female; Humans; Magnetic Fields; Magnetic Resonance Imaging; Male; Nausea; Vertigo | 2014 |
Infusion technique of hematopoietic progenitor cells and related adverse events (CME).
Topics: Acetaminophen; Adolescent; Adult; Aged; Blood Preservation; Child; Child, Preschool; Cryopreservatio | 2014 |
Induction and antagonism of pica induced by teriparatide in rats.
Topics: Age Factors; Animals; Anorexia; Antiemetics; Diphenhydramine; Disease Models, Animal; Dopamine D2 Re | 2015 |
Benadryl hydrochloride given intravenously to control postoperative nausea and vomiting.
Topics: Diphenhydramine; Humans; Nausea; Postoperative Nausea and Vomiting; Vomiting | 1953 |
An evaluation of antiemetic drugs in the control of postoperative nausea and vomiting.
Topics: Anti-Allergic Agents; Antiemetics; Chlorpromazine; Diphenhydramine; Histamine H1 Antagonists; Humans | 1955 |
On special uses of diphenhydramine hydrochloride in the somatic therapy ward of a psychiatric hospital.
Topics: Diphenhydramine; Electroconvulsive Therapy; Hospitals, Psychiatric; Humans; Movement Disorders; Naus | 1958 |
[FAINTING AND NAUSEA OF PREGNANCY. ITS THERAPY WITH A COMBINATION OF A NEW POORLY SOLUBLE SALT OF DIPHENHYDRAMINE, SCOPOLAMINE AND PYRIDOXINE].
Topics: Diphenhydramine; Female; Humans; Hyperemesis Gravidarum; Nausea; Pharmacology; Pregnancy; Pyridoxine | 1963 |
The intravenous use of diphenhydramine hydrochloride in the control of nausea and vomiting.
Topics: Diphenhydramine; Humans; Injections, Intravenous; Motion Sickness; Nausea; Vomiting | 1951 |
[Paclitaxel plus carboplatin in ovarian cancer-comparison of adverse effects between monthly and weekly administration].
Topics: Adult; Aged; Anorexia; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Dex | 2004 |
Challenges in palliative care research: one experience.
Topics: Antiemetics; Attitude of Health Personnel; Diphenhydramine; Drug Combinations; Ethics Committees, Re | 2004 |
Efficacy of intravenous diphenhydramine versus intravenous DHE-45 in the treatment of severe migraine headache.
Topics: Adolescent; Adult; Aged; Analgesics, Non-Narcotic; Antiemetics; Dihydroergotamine; Diphenhydramine; | 2005 |
Tolerability of the compound ABHR in hospice patients.
Topics: Aged; Antiemetics; Cohort Studies; Diphenhydramine; Drug Combinations; Female; Haloperidol; Hospice | 2005 |
A case of metoclopramide-induced oculogyric crisis in a 16-year-old girl with cystic fibrosis.
Topics: Adolescent; Antiemetics; Diphenhydramine; Dopamine Antagonists; Dystonia; Female; Fundoplication; Hi | 2006 |
Lorazepam, diphenhydramine, and haloperidol transdermal gel for rescue from chemotherapy-induced nausea/vomiting: results of two pilot trials.
Topics: Administration, Cutaneous; Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Clini | 2008 |
Antihistamines as prophylaxis against side reactions to intravenous fluorescein.
Topics: Adolescent; Adult; Aged; Anaphylaxis; Diphenhydramine; Dizziness; Female; Fluorescein Angiography; F | 1980 |
DAB: a three-drug combination provides alternative to 5-HT3 receptor drugs.
Topics: Antineoplastic Agents; Dexamethasone; Diphenhydramine; Drug Combinations; Humans; Lorazepam; Nausea; | 1995 |
On the relationship between nausea and vomiting in patients undergoing chemotherapy. Italian Group for Antiemetic Research.
Topics: Antiemetics; Cisplatin; Confounding Factors, Epidemiologic; Dexamethasone; Diphenhydramine; Factor A | 1994 |
Cost and cost-effectiveness analysis of ondansetron versus metoclopramide regimens: a hospital perspective from Italy.
Topics: Chemotherapy, Adjuvant; Cisplatin; Costs and Cost Analysis; Dexamethasone; Diphenhydramine; Dose-Res | 1994 |
Safety and efficacy of a continuous infusion, patient controlled anti-emetic pump to facilitate outpatient administration of high-dose chemotherapy.
Topics: Adult; Ambulatory Care; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Breast Neoplasm | 1999 |
Emergency! Prochlorperazine-induced dystonia.
Topics: Adolescent; Animals; Antiemetics; Diagnosis, Differential; Diphenhydramine; Dystonia; Emergencies; F | 1999 |
Potential anaphylactic shock with abciximab readministration.
Topics: Abciximab; Anaphylaxis; Anti-Inflammatory Agents; Antibodies, Monoclonal; Bradycardia; Diphenhydrami | 2002 |
Diphenhydramine for nausea and vomiting related to cancer chemotherapy with cisplatin.
Topics: Adult; Aged; Cisplatin; Dexamethasone; Diphenhydramine; Drug Therapy, Combination; Female; Humans; M | 1992 |
Compounding nausea aid.
Topics: Benztropine; Chemistry, Pharmaceutical; Dexamethasone; Diphenhydramine; Drug Combinations; Drug Comp | 1991 |
Antiemetic suppositories.
Topics: Administration, Rectal; Dexamethasone; Diphenhydramine; Drug Combinations; Humans; Metoclopramide; N | 1991 |
[A combined anti-emesis therapy of oral prednisolone and alprazolam for cisplatin-induced delayed emesis].
Topics: Administration, Oral; Adult; Aged; Alprazolam; Antineoplastic Combined Chemotherapy Protocols; Carci | 1990 |
A pilot study of metoclopramide, dexamethasone, diphenhydramine and lorazepam in prevention of nausea and vomiting in cisplatin-treated male patients.
Topics: Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Dexamethasone; Diphenhydramine; Drug Eval | 1990 |
Phase I clinical and pharmacokinetic study of taxol.
Topics: Adenocarcinoma; Adult; Aged; Aged, 80 and over; Alkaloids; Alopecia; Cimetidine; Dexamethasone; Diph | 1987 |
Psychomotor performances and subjective feeling studies with antihistamine.
Topics: Adult; Benzhydryl Compounds; Chlorpheniramine; Cognition; Diphenhydramine; Female; Humans; Male; Nau | 1986 |
Oral metoclopramide with or without diphenhydramine: potential for prevention of late nausea and vomiting induced by cisplatin.
Topics: Adolescent; Adult; Age Factors; Aged; Cisplatin; Diphenhydramine; Female; Humans; Male; Metocloprami | 1988 |
[The prevention of CDDP-induced emesis with a combination regimen including metoclopramide, dexamethasone, droperidol and diphenhydramine].
Topics: Adult; Antiemetics; Antineoplastic Combined Chemotherapy Protocols; Cisplatin; Cyclophosphamide; Dex | 1987 |
Metoclopramide: dose-related toxicity and preliminary antiemetic studies in children receiving cancer chemotherapy.
Topics: Adolescent; Adult; Akathisia, Drug-Induced; Antineoplastic Agents; Basal Ganglia Diseases; Child; Di | 1985 |