diphenhydramine has been researched along with Muscle Relaxation in 8 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Muscle Relaxation: That phase of a muscle twitch during which a muscle returns to a resting position.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Pretreatment with atropine, phentolamine, and diphenhydramine antagonized the motilin- and bombesin-induced contraction." | 1.29 | Effects of various peptides on isolated rabbit lower esophageal sphincter. ( Kohjitani, A; Obara, H; Okada, S; Shirakawa, J, 1996) |
| "Pretreatment with diphenhydramine (5 x 10(-7)) on aortic rings from 12 and 52-week age matched rats resulted in qualitatively similar histamine dose-response curves that were displaced about two orders of magnitude to the right, indicative of H1 receptor competitive antagonism." | 1.28 | Histamine relaxation of aortic rings from diabetic rats. ( Chang, KS; Tanz, RD; Weller, TS, 1989) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (62.50) | 18.7374 |
| 1990's | 2 (25.00) | 18.2507 |
| 2000's | 1 (12.50) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Regoli, D | 1 |
| D'Orléans-Juste, P | 1 |
| Escher, E | 1 |
| Mizrahi, J | 1 |
| Carrier, GO | 1 |
| White, RE | 1 |
| Kirby, ML | 1 |
| Kohjitani, A | 1 |
| Shirakawa, J | 1 |
| Okada, S | 1 |
| Obara, H | 1 |
| Kim, ND | 1 |
| Kang, SY | 1 |
| Park, JH | 1 |
| Schini-Kerth, VB | 1 |
| Kapilevich, LV | 1 |
| Anfinogenova, YD | 1 |
| Nosarev, AV | 1 |
| Baskakov, MB | 1 |
| Kovalev, IV | 1 |
| D'yakova, EY | 1 |
| Medvedev, MA | 1 |
| Rattan, S | 1 |
| Goyal, RK | 1 |
| Tanz, RD | 1 |
| Chang, KS | 1 |
| Weller, TS | 1 |
| Ponce-Monter, H | 1 |
| Estrada, AV | 1 |
| Pedrón, N | 1 |
| Valencia, A | 1 |
| Gallegos, AJ | 1 |
8 other studies available for diphenhydramine and Muscle Relaxation
| Article | Year |
|---|---|
Receptors for substance P. I. The pharmacological preparations.
Topics: Animals; Atropine; Diphenhydramine; Dogs; Female; Guinea Pigs; Heart; Ileum; In Vitro Techniques; In | 1984 |
Histamine-induced relaxation of rat aorta. Importance of H1 receptor and vascular endothelium.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Cimetidine; Diphenhydramine; Endothelium; Histamine; | 1984 |
Effects of various peptides on isolated rabbit lower esophageal sphincter.
Topics: Animals; Atropine; Bombesin; Calcitonin Gene-Related Peptide; Diphenhydramine; Dose-Response Relatio | 1996 |
Ginsenoside Rg3 mediates endothelium-dependent relaxation in response to ginsenosides in rat aorta: role of K+ channels.
Topics: Adrenergic beta-Antagonists; Animals; Antineoplastic Agents, Phytogenic; Aorta, Thoracic; Atropine; | 1999 |
Histaminergic regulation of smooth muscles in rabbit pulmonary arteries.
Topics: Animals; Culture Techniques; Diphenhydramine; Dose-Response Relationship, Drug; Endothelium, Vascula | 2001 |
Evidence of 5-HT participation in vagal inhibitory pathway to opossum LES.
Topics: Animals; Atropine; Diphenhydramine; Esophagogastric Junction; Female; Fenclonine; Hexamethonium Comp | 1978 |
Histamine relaxation of aortic rings from diabetic rats.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Diphenhydramine; Endothelium, Vascular; H | 1989 |
The zoapatle. X. The in vitro effect of zoapatle aqueous crude extract (ZACE) and histamine upon rat and guinea pig uterine strips.
Topics: Animals; Cimetidine; Diphenhydramine; Female; Guinea Pigs; Histamine; Histamine H1 Antagonists; Hist | 1985 |