diphenhydramine has been researched along with Muscle Contraction in 111 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Muscle Contraction: A process leading to shortening and/or development of tension in muscle tissue. Muscle contraction occurs by a sliding filament mechanism whereby actin filaments slide inward among the myosin filaments.
| Excerpt | Relevance | Reference |
|---|---|---|
| " Pardaxin contracted the ileum and subsequently abolished muscle contraction to 5-hydroxytryptamine (5-HT), but did not affect the responses to acetylcholine (ACh) and substance P(SP)." | 7.67 | Pardaxin produces postjunctional muscle contraction in guinea-pig intestinal smooth muscle. ( Primor, N, 1984) |
| " To investigate this observation further, we examined the effects of phosphoramidon, an inhibitor of a neutral endopeptidase, on contraction induced by mediators of anaphylaxis." | 3.69 | Phosphoramidon augments contraction of guinea pig tracheal smooth muscle induced by histamine and leukotriene-D4. ( Bosnjak, ZJ; Coon, RL; Tudorić, N, 1994) |
| " Pardaxin contracted the ileum and subsequently abolished muscle contraction to 5-hydroxytryptamine (5-HT), but did not affect the responses to acetylcholine (ACh) and substance P(SP)." | 3.67 | Pardaxin produces postjunctional muscle contraction in guinea-pig intestinal smooth muscle. ( Primor, N, 1984) |
| "Pretreatment with atropine, phentolamine, and diphenhydramine antagonized the motilin- and bombesin-induced contraction." | 1.29 | Effects of various peptides on isolated rabbit lower esophageal sphincter. ( Kohjitani, A; Obara, H; Okada, S; Shirakawa, J, 1996) |
| "Pretreatment with diphenhydramine or methysergide significantly reduced trimucase-induced paw swelling, while aspirin had no effect." | 1.28 | Comparison of kinin-forming and amidolytic activities of four trimucases, oedema-producing and kinin-releasing enzymes, from Trimeresurus mucrosquamatus venom. ( Hsu, MF; Teng, CM; Wang, JP, 1992) |
| "In imipramine-treated animals LFES elicited much stronger contractions than in the controls." | 1.28 | Effects of histaminergic drugs on the contractile activity of smooth muscles from imipramine-treated rats. ( Todorov, S, 1990) |
| "Pretreatment with diphenhydramine (5 x 10(-7)) on aortic rings from 12 and 52-week age matched rats resulted in qualitatively similar histamine dose-response curves that were displaced about two orders of magnitude to the right, indicative of H1 receptor competitive antagonism." | 1.28 | Histamine relaxation of aortic rings from diabetic rats. ( Chang, KS; Tanz, RD; Weller, TS, 1989) |
| "Histamine tachyphylaxis was marked, and sometimes irreversible." | 1.27 | Selectivity of histamine for the proximal muscle loop of the cat pylorus. ( Schulze-Delrieu, K; Shirazi, SS, 1984) |
| "Byssinosis is an occupational respiratory disease contracted by cotton mill workers who inhale cotton mill dust." | 1.27 | Bioassays of smooth muscle contracting agents in cotton mill dust and bract extracts: arachidonic acid metabolites as possible mediators of the acute byssinotic reaction. ( Ainsworth, SK; Bray, VJ; Cordova-Salinas, M; Mundie, TG, 1983) |
| " The H1-histamine antagonists, (+)-chloropheniramine and diphenhydramine, caused a parallel shift to the right of the splenic extract dose-response curve without suppression of the maximum response." | 1.27 | H1-histamine receptors may mediate the contractile response of guinea-pig ileum to 'histamine-free' splenic extracts. ( Ainz, LF; Casis, E; de Gandarias, JM; Gil-Rodrigo, CE; Goiriena de Gandarias, JJ, 1983) |
| "Pretreatment with diphenhydramine, BW-755C and kadsurenone (or alprazolam) improved survival to 64% (i." | 1.27 | Inhibition of the platelet activating factor mediated component of guinea pig anaphylaxis by receptor antagonists. ( Darius, H; Lefer, AM; Smith, JB, 1986) |
| " In the isolated guinea pig ileum, the dose-response curve for histamine was shifted to the right by 10(-8) mol/l of diphenhydramine, clemastine or azelastine to the same degree." | 1.26 | Effects of azelastine hydrochloride, a new antiallergic drug, on the gastrointestinal tract. ( Igarashi, T; Murakami, M; Shoji, T; Yamanaka, T, 1981) |
| "Triprolidine (0." | 1.26 | N,N-Diethyl-2-(1-pyridyl)ethylamine, a partial agonist for the histamine receptor in guinea pig ileum. ( Cook, DA; Kenakin, TP, 1980) |
| " In vitro dose-response curves to gastrin I, CCK, and the octapeptide of CCK (OP) demonstrated that both CCK and OP were partial agonists on the LES muscle." | 1.25 | Mechanism of cholecystokinin inhibition of lower esophageal sphincter pressure. ( Cohen, S; DiMarino, AJ; Fisher, RS, 1975) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 89 (80.18) | 18.7374 |
| 1990's | 18 (16.22) | 18.2507 |
| 2000's | 2 (1.80) | 29.6817 |
| 2010's | 2 (1.80) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Janssens, F | 1 |
| Torremans, J | 1 |
| Janssen, M | 1 |
| Stokbroekx, RA | 1 |
| Luyckx, M | 1 |
| Janssen, PA | 1 |
| Carceller, E | 1 |
| Merlos, M | 1 |
| Giral, M | 1 |
| Balsa, D | 1 |
| Almansa, C | 1 |
| Bartrolí, J | 1 |
| García-Rafanell, J | 1 |
| Forn, J | 1 |
| Yao, QY | 1 |
| Chen, DP | 1 |
| Ye, DM | 1 |
| Diao, YP | 1 |
| Lin, Y | 2 |
| Chen, D | 1 |
| Xiong, Y | 1 |
| Wang, L | 1 |
| Lv, B | 1 |
| BARTLET, AL | 1 |
| JUDAH, JD | 1 |
| WILLOUGHBY, DA | 1 |
| SHARKEY, J | 2 |
| BOYARSKY, S | 1 |
| CATACUTAN-LABAY, P | 1 |
| MARTINEZ, J | 1 |
| Nachev, Ch | 1 |
| Ivancheva, C | 1 |
| Apostolova, MD | 1 |
| Radomirov, R | 1 |
| Gershbein, LL | 1 |
| Denton, RW | 1 |
| Yamanaka, T | 1 |
| Shoji, T | 1 |
| Murakami, M | 1 |
| Igarashi, T | 1 |
| Regal, JF | 4 |
| Onnen, I | 1 |
| Olive, G | 1 |
| Douglas, JS | 1 |
| Duncan, PG | 1 |
| Mukhopadhyay, A | 1 |
| Mizrahi, J | 3 |
| D'Orléans-Juste, P | 3 |
| Drapeau, G | 1 |
| Escher, E | 3 |
| Regoli, D | 5 |
| Primor, N | 2 |
| Taniyama, K | 1 |
| Kusunoki, M | 1 |
| Tanaka, C | 1 |
| Nakanishi, H | 1 |
| Fukui, K | 1 |
| Kanke, M | 1 |
| Sakuma, T | 1 |
| Shirazi, SS | 1 |
| Schulze-Delrieu, K | 1 |
| Cordeior, RS | 1 |
| Aragão, JB | 1 |
| Morhy, L | 1 |
| Mundie, TG | 1 |
| Cordova-Salinas, M | 1 |
| Bray, VJ | 1 |
| Ainsworth, SK | 1 |
| Ainz, LF | 1 |
| Casis, E | 1 |
| de Gandarias, JM | 1 |
| Gil-Rodrigo, CE | 1 |
| Goiriena de Gandarias, JJ | 1 |
| Snowden, JM | 1 |
| Kennedy, DF | 1 |
| Cliff, WJ | 1 |
| Steward, A | 1 |
| Bottomley, KM | 1 |
| Lewis, S | 1 |
| Rising, TJ | 1 |
| Carrier, GO | 1 |
| White, RE | 1 |
| Kirby, ML | 1 |
| Wang, SR | 1 |
| Yang, CM | 1 |
| Wang, SM | 1 |
| Pickering, RJ | 2 |
| Clanachan, AS | 1 |
| Courtney, DF | 1 |
| Scott, GW | 1 |
| Kenakin, TP | 1 |
| Cook, DA | 1 |
| Biancani, P | 1 |
| CiCalzi, LK | 1 |
| McCallum, RW | 1 |
| Quirion, R | 1 |
| Rioux, F | 2 |
| St-Pierre, S | 1 |
| Eastman, AY | 1 |
| Marco, EJ | 1 |
| Balfagón, G | 1 |
| Marín, J | 1 |
| Gómez, B | 1 |
| Lluch, S | 1 |
| Liu, X | 1 |
| Lin, KW | 1 |
| Matera, MG | 1 |
| De Santis, D | 1 |
| D'Agostino, B | 1 |
| Pallotta, M | 1 |
| Vacca, C | 1 |
| Cazzola, M | 1 |
| Rossi, F | 1 |
| Tudorić, N | 1 |
| Coon, RL | 1 |
| Bosnjak, ZJ | 1 |
| Suyama, N | 1 |
| Todoki, K | 1 |
| Okabe, E | 1 |
| Miyahara, H | 1 |
| Imayama, S | 1 |
| Hori, Y | 1 |
| Suzuki, H | 1 |
| Poriadin, GV | 1 |
| Samsonov, AN | 1 |
| Makarkov, AI | 1 |
| KAMEI, CH | 1 |
| Kohjitani, A | 1 |
| Shirakawa, J | 1 |
| Okada, S | 1 |
| Obara, H | 1 |
| Conte, B | 1 |
| Parlani, M | 1 |
| Lopez, G | 1 |
| Cirillo, R | 1 |
| Maggi, CA | 1 |
| Manzini, S | 1 |
| Kapilevich, LV | 1 |
| Anfinogenova, YD | 1 |
| Nosarev, AV | 1 |
| Baskakov, MB | 1 |
| Kovalev, IV | 1 |
| D'yakova, EY | 1 |
| Medvedev, MA | 1 |
| Rispat, G | 1 |
| Burgi, H | 1 |
| Cosnier, D | 1 |
| Duchêne-Marullaz, P | 1 |
| Streichenberger, G | 1 |
| Gadacz, TR | 1 |
| Fisher, RS | 1 |
| DiMarino, AJ | 1 |
| Cohen, S | 2 |
| Salimi, M | 1 |
| Khoyi, MA | 1 |
| Dibai, MA | 1 |
| Adams, GK | 1 |
| Lichtenstein, LM | 1 |
| Himori, N | 1 |
| Sprügel, W | 1 |
| Schubert, E | 2 |
| Mitznegg, P | 2 |
| Heim, F | 2 |
| Hasl, G | 1 |
| Pauly, H | 1 |
| Todorov, S | 4 |
| DeFelice, A | 1 |
| Wilson, W | 1 |
| Ambre, J | 1 |
| Domschke, W | 1 |
| Strunz, U | 1 |
| Domschke, S | 1 |
| Schwemmle, K | 1 |
| Demling, L | 1 |
| Pennefather, JN | 1 |
| Parness, J | 1 |
| Zlotkin, E | 1 |
| Teng, CM | 1 |
| Hsu, MF | 1 |
| Wang, JP | 1 |
| Vassilev, P | 2 |
| Staneva-Stoytcheva, D | 2 |
| Mutafova-Yambolieva, V | 2 |
| Obi, T | 1 |
| Matsumoto, M | 1 |
| Nishio, A | 1 |
| Yamamoto, LA | 1 |
| Soldera, JC | 1 |
| Emim, JA | 1 |
| Godinho, RO | 1 |
| Souccar, C | 1 |
| Lapa, AJ | 1 |
| Onodera, S | 1 |
| Yoshinaga, M | 1 |
| Takenaga, K | 1 |
| Toyoshima, A | 1 |
| Uchiyama, T | 1 |
| Nishimoto, T | 1 |
| Yokoyama, M | 2 |
| Fukuzaki, H | 2 |
| Awano, K | 1 |
| Tanz, RD | 1 |
| Chang, KS | 1 |
| Weller, TS | 1 |
| Nolan, JC | 1 |
| Stephens, DJ | 1 |
| Proakis, AG | 1 |
| Leonard, CA | 1 |
| Johnson, DN | 1 |
| Kilpatrick, BF | 1 |
| Foxwell, MH | 1 |
| Yanni, JM | 1 |
| Kitazawa, T | 1 |
| Hoshi, T | 1 |
| Temma, K | 1 |
| Kondo, H | 1 |
| Bottaro, D | 1 |
| Shepro, D | 1 |
| Peterson, S | 1 |
| Hechtman, HB | 1 |
| Zamfirova, R | 1 |
| Darius, H | 1 |
| Smith, JB | 1 |
| Lefer, AM | 1 |
| Souhrada, M | 1 |
| Souhrada, JF | 1 |
| Auguet, M | 1 |
| Delaflotte, S | 1 |
| Hellegouarch, A | 1 |
| Guillon, JM | 1 |
| Baranes, J | 1 |
| Pirotzky, E | 1 |
| Clostre, F | 1 |
| Braquet, P | 1 |
| Kolbeck, RC | 1 |
| Chaudhary, BA | 1 |
| Speir, WA | 1 |
| Altura, BM | 2 |
| Altura, BT | 1 |
| Gagnon, DJ | 2 |
| Sirois, P | 2 |
| Boucher, PJ | 1 |
| Khairallah, PA | 1 |
| Page, IH | 1 |
| Türker, RK | 1 |
| Park, WK | 1 |
| Grumelli, E | 1 |
| Goi, A | 1 |
| Wellens, D | 1 |
| Miyake, T | 1 |
| Sekiya, A | 1 |
| Kanda, Z | 1 |
| Karim, SM | 1 |
| Tohya, Y | 1 |
| Sasagawa, S | 1 |
| Hudgins, PM | 1 |
| Stubbins, JF | 1 |
| Tuttle, RR | 1 |
| Moran, NC | 1 |
| Trottier, RW | 1 |
| Malone, MH | 1 |
| Mittag, TW | 1 |
| Tormay, A | 1 |
| Rocha e Silva, M | 1 |
| Fernandes, F | 1 |
| Antonio, A | 1 |
| Teraki, Y | 1 |
| Saenz, RV | 1 |
| Sowell, JW | 1 |
| Okamura, T | 1 |
| Shina, Y | 1 |
| Story, ME | 1 |
| Bentley, GA | 1 |
| Wakabayashi, K | 1 |
| Yamada, S | 1 |
| Osman, OH | 1 |
| Ismail, M | 1 |
| el-Asmar, MF | 1 |
| Ibrahim, SA | 1 |
| Lu, HH | 1 |
| Hsu, HK | 1 |
| Lin, CI | 1 |
| Yamanaka, I | 1 |
| Dowdy, EG | 1 |
| Sherman, WT | 1 |
| Gautieri, RF | 1 |
| Dulinets, VV | 1 |
| Lipshutz, W | 1 |
| Tuch, AF | 1 |
| Ichihashi, M | 1 |
| Lee, WH | 1 |
| Fujiwara, M | 1 |
| Vick, JA | 1 |
| Herman, EH | 1 |
| Levy, JV | 1 |
| Killebrew, E | 1 |
| Takagi, K | 1 |
| Takayanagi, I | 1 |
| Kaplan, N | 1 |
| Newman, HR | 1 |
| Elkin, M | 1 |
| Joshi, NK | 1 |
| Deshpande, VR | 1 |
| Rajapurkar, MV | 1 |
| Domer, FR | 1 |
| Trivedi, CP | 1 |
111 other studies available for diphenhydramine and Muscle Contraction
| Article | Year |
|---|---|
New antihistaminic N-heterocyclic 4-piperidinamines. 1. Synthesis and antihistaminic activity of N-(4-piperidinyl)-1H-benzimidazol-2-amines.
Topics: Administration, Oral; Animals; Benzimidazoles; Biological Assay; Chemical Phenomena; Chemistry; Guin | 1985 |
[(3-Pyridylalkyl)piperidylidene]benzocycloheptapyridine derivatives as dual antagonists of PAF and histamine.
Topics: Anaphylaxis; Animals; Benzocycloheptenes; Blood Pressure; Guinea Pigs; Histamine; Histamine H1 Antag | 1994 |
Modulatory effects of taurine on jejunal contractility.
Topics: Adrenergic alpha-Antagonists; Adrenergic beta-Antagonists; Animals; Atropine; Calcium Channel Blocke | 2014 |
Characteristics of emodin on modulating the contractility of jejunal smooth muscle.
Topics: Animals; Atropine; Constipation; Diarrhea; Diphenhydramine; Disease Models, Animal; Dose-Response Re | 2012 |
THE ACTION OF HISTAMINE ON THE ISOLATED HEART.
Topics: Animals; Anti-Allergic Agents; Blood Circulation; Coronary Vessels; Diphenhydramine; Ethanolamines; | 1963 |
INHIBITORS OF SODIUM DEPENDENT RELAXATION OF GUINEA-PIG ILEUM.
Topics: Calcium; Dibucaine; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Ileum; Muscle Contractio | 1964 |
THE IN VIVO EFFECTS OF HISTAMINE AND BENADRYL ON THE PERISTALSIS OF THE CANINE URETER AND PLASMA POTASSIUM LEVELS.
Topics: Animals; Blood; Diphenhydramine; Dogs; Gastrointestinal Motility; Histamine; Muscle Contraction; Mus | 1965 |
Cholinergic responses of ileal longitudinal muscle under short-lasting exposure to cupric ions.
Topics: Animals; Atropine; Carbachol; Cholinergic Agonists; Cholinergic Fibers; Copper; Diphenhydramine; Dos | 2008 |
In vitro contractility of smooth muscle by cholecystokinin concentrates and the antagonistic action of various hormones and drugs.
Topics: Adrenal Cortex Hormones; Animals; Cholecystokinin; Diphenhydramine; Dogs; Drug Antagonism; Epinephri | 1967 |
Effects of azelastine hydrochloride, a new antiallergic drug, on the gastrointestinal tract.
Topics: Animals; Bile; Clemastine; Digestive System; Diphenhydramine; Gastrointestinal Motility; Histamine H | 1981 |
C5a-induced aortic contraction: effect of an antihistamine and inhibitors of arachidonate metabolism.
Topics: 5,8,11,14-Eicosatetraynoic Acid; Animals; Aorta, Thoracic; Arachidonic Acid; Arachidonic Acids; Aspi | 1982 |
Desensitization of the isolated guinea pig ileum to antihistaminic agents.
Topics: Animals; Diphenhydramine; Guinea Pigs; Histamine H1 Antagonists; Ileum; In Vitro Techniques; Kinetic | 1983 |
The antagonism of histamine-induced tracheal and bronchial muscle contraction by diphenhydramine: effect of maturation.
Topics: Aging; Animals; Bronchi; Carbachol; Diphenhydramine; Guinea Pigs; Histamine; Histamine Antagonists; | 1984 |
Partial agonists and antagonists for substance P.
Topics: Animals; Atropine; Diphenhydramine; Dogs; Guinea Pigs; In Vitro Techniques; Indomethacin; Muscle Con | 1983 |
Receptors for substance P. I. The pharmacological preparations.
Topics: Animals; Atropine; Diphenhydramine; Dogs; Female; Guinea Pigs; Heart; Ileum; In Vitro Techniques; In | 1984 |
Pardaxin produces postjunctional muscle contraction in guinea-pig intestinal smooth muscle.
Topics: Acetylcholine; Animals; Diphenhydramine; Drug Interactions; Electric Stimulation; Fish Venoms; Guine | 1984 |
Undeca- and octa-peptide antagonists for substance P, a study on the guinea pig trachea.
Topics: Animals; Diphenhydramine; Eledoisin; Female; Guinea Pigs; In Vitro Techniques; Kinetics; Male; Muscl | 1984 |
Inhibitory histamine H2-receptor in the guinea-pig urinary bladder.
Topics: Acetylcholine; Animals; Calcium; Choline; Cimetidine; Diphenhydramine; Electric Stimulation; Female; | 1984 |
Histamine receptor in the rabbit vas deferens.
Topics: Animals; Cimetidine; Diphenhydramine; Electric Stimulation; Histamine; In Vitro Techniques; Male; Mu | 1982 |
Selectivity of histamine for the proximal muscle loop of the cat pylorus.
Topics: Acetylcholine; Animals; Cats; Diphenhydramine; Histamine; In Vitro Techniques; Muscle Contraction; M | 1984 |
IgG vs IgE: mediators of antigen-induced guinea pig tracheal contraction.
Topics: Animals; Antigens; Catechols; Chromones; Diphenhydramine; Guinea Pigs; Immunoglobulin E; Immunoglobu | 1984 |
The presence of histamine in Cnidosculus oligandrus (Euphorbiaceae).
Topics: Animals; Capillary Permeability; Chromatography, Thin Layer; Diphenhydramine; Female; Fluorometry; G | 1983 |
Bioassays of smooth muscle contracting agents in cotton mill dust and bract extracts: arachidonic acid metabolites as possible mediators of the acute byssinotic reaction.
Topics: Acute Disease; Animals; Arachidonic Acids; Byssinosis; Diphenhydramine; Dust; Gossypium; In Vitro Te | 1983 |
H1-histamine receptors may mediate the contractile response of guinea-pig ileum to 'histamine-free' splenic extracts.
Topics: Animals; Cattle; Diphenhydramine; Dose-Response Relationship, Drug; Female; Guinea Pigs; Histamine; | 1983 |
The contractile properties of wound granulation tissue.
Topics: Animals; Diphenhydramine; Granulation Tissue; Isotonic Contraction; Models, Biological; Muscle Contr | 1984 |
Low level antigen responses in guinea-pig lung strip.
Topics: Anaphylaxis; Animals; Antigens; Diphenhydramine; Female; Guinea Pigs; Histamine; In Vitro Techniques | 1984 |
Histamine-induced relaxation of rat aorta. Importance of H1 receptor and vascular endothelium.
Topics: Animals; Aorta, Thoracic; Binding, Competitive; Cimetidine; Diphenhydramine; Endothelium; Histamine; | 1984 |
[Characterization of slow reacting substance of anaphylaxis in asthmatic sputum].
Topics: Adult; Animals; Arylsulfatases; Asthma; Chromones; Diphenhydramine; Female; Guinea Pigs; Histamine; | 1984 |
C5a and antigen-induced tracheal contraction: effect of a combination of an antihistamine and cyclo-oxygenase inhibitors.
Topics: Animals; Antigens; Aspirin; Complement C5; Complement C5a; Diphenhydramine; Drug Synergism; Ethanol; | 1983 |
Stimulatory and inhibitory histamine receptors in canine cystic duct.
Topics: Animals; Cimetidine; Cystic Duct; Diphenhydramine; Dogs; Female; Hemodynamics; Male; Muscle Contract | 1982 |
N,N-Diethyl-2-(1-pyridyl)ethylamine, a partial agonist for the histamine receptor in guinea pig ileum.
Topics: Animals; Diphenhydramine; Ethylamines; Guinea Pigs; Ileum; In Vitro Techniques; Male; Muscle Contrac | 1980 |
Mechanism of histamine-induced excitation of the cat pylorus.
Topics: Animals; Catecholamines; Cats; Cimetidine; Diphenhydramine; Histamine; Muscle Contraction; Muscle, S | 1981 |
The stimulatory effects of neurotensin and related peptides in rat stomach strips and guinea-pig atria.
Topics: Animals; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Female; Guinea Pigs; In Vitr | 1980 |
C5a induced tracheal contraction: a histamine independent mechanism.
Topics: Animals; Antigens; Atropine; Complement C5; Diphenhydramine; Guinea Pigs; Histamine; Lung; Male; Met | 1980 |
Indirect adrenergic effect of histamine in cat cerebral arteries.
Topics: Animals; Cats; Cerebral Arteries; Cocaine; Diphenhydramine; Female; Histamine; In Vitro Techniques; | 1980 |
[Effect and its mechanism of substance P on contractile activity of isolated antral muscle strips of rat].
Topics: Animals; Cyproheptadine; Diphenhydramine; Dose-Response Relationship, Drug; Hexamethonium; Hexametho | 1994 |
Role of 5-hydroxytryptamine in mediating adenosine-induced airway contraction.
Topics: Analysis of Variance; Animals; Atropine; Diphenhydramine; Dose-Response Relationship, Drug; Epitheli | 1995 |
Phosphoramidon augments contraction of guinea pig tracheal smooth muscle induced by histamine and leukotriene-D4.
Topics: Anaphylaxis; Animals; Antigens; Dinoprost; Diphenhydramine; Glycopeptides; Guinea Pigs; Histamine; I | 1994 |
[A mechanism underlying histamine-induced contraction in isolated rabbit lingual artery].
Topics: Animals; Caffeine; Calcium; Diphenhydramine; Histamine; Histamine Antagonists; In Vitro Techniques; | 1994 |
Cellular mechanisms of the steroid-induced vascular responses in the rabbit ear artery.
Topics: Acetylcholine; Animals; Arteries; Dexamethasone; Diphenhydramine; Ear, External; Electric Stimulatio | 1993 |
[The effect of ADP on the contractile activity of guinea pig intestinal smooth muscle].
Topics: Adenosine; Adenosine Diphosphate; Adrenergic alpha-Agonists; Adrenergic beta-Agonists; Anaphylaxis; | 1995 |
EFFECTS OF HISTAMINE AND RELATED COMPOUNDS ON THE BOVINE IRIS DILATOR.
Topics: Analysis of Variance; Animals; Cattle; Chlorpheniramine; Cimetidine; Diphenhydramine; Dose-Response | 1996 |
Effects of various peptides on isolated rabbit lower esophageal sphincter.
Topics: Animals; Atropine; Bombesin; Calcitonin Gene-Related Peptide; Diphenhydramine; Dose-Response Relatio | 1996 |
Inflammatory and motor responses by tachykinins in the guinea-pig oesophageal sphincter.
Topics: Animals; Dipeptides; Diphenhydramine; Dose-Response Relationship, Drug; Esophagogastric Junction; Ev | 1998 |
Histaminergic regulation of smooth muscles in rabbit pulmonary arteries.
Topics: Animals; Culture Techniques; Diphenhydramine; Dose-Response Relationship, Drug; Endothelium, Vascula | 2001 |
General pharmacological properties of a new non-opiate antitussive: zipeprol (3024 CERM). I. Action on respiratory function and acute toxicity.
Topics: Administration, Oral; Anesthetics, Local; Animals; Antitussive Agents; Bronchi; Cats; Codeine; Cough | 1976 |
Effect of an H-2 antagonist on gallbladder contraction.
Topics: Animals; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Gallbladder; Guinea Pigs; Hi | 1978 |
Mechanism of cholecystokinin inhibition of lower esophageal sphincter pressure.
Topics: Acetylcholine; Animals; Atropine; Cholecystokinin; Diphenhydramine; Dose-Response Relationship, Drug | 1975 |
Effect of ethacrynic acid on guinea pig ileum.
Topics: Animals; Atropine; Diphenhydramine; Dose-Response Relationship, Drug; Electric Stimulation; Ethacryn | 1979 |
Antagonism of antigen-induced contraction of guinea pig and human airways.
Topics: Airway Resistance; Animals; Antigens; Asthma; Benzopyrans; Bronchi; Diphenhydramine; Ethers; Guinea | 1977 |
Effects of hexoestrol on the contractility of the isolated, blood-perfused canine papillary muscle and of the guinea-pig ileum.
Topics: Acetylcholine; Animals; Atropine; Barium; Coronary Circulation; Diphenhydramine; Dogs; Female; Hexes | 1977 |
Immediate X-radiation induced contractions of the isolated guinea pig terminal ileum: the localization of the effect by drugs.
Topics: Acetylcholine; Animals; Atropine; Diphenhydramine; Female; Guinea Pigs; Hexamethonium Compounds; Ile | 1977 |
New method for in vitro studies of the histaminergic receptors in tracheal smooth muscle of male and female guinea-pigs.
Topics: Animals; Diphenhydramine; Female; Guinea Pigs; Histamine; In Vitro Techniques; Male; Muscle Contract | 1977 |
Vasoactive effects of methanol and sodium formate on isolated canine basilar artery.
Topics: Animals; Barium; Basilar Artery; Cinanserin; Diphenhydramine; Dogs; Drug Interactions; Formates; His | 1976 |
[Mode of action of bisacodyl (dulcolax) on isolated muscles of human colon (author's transl)].
Topics: Acetylcholine; Bisacodyl; Colon; Cresols; Diphenhydramine; Drug Antagonism; Histamine; Humans; Muscl | 1975 |
The effects of cocaine and diphenhydramine upon the reactivity of rat vas deferens to supramaximal doses of noradrenaline and of other agonists: the mode of action of cocaine.
Topics: Acetylcholine; Animals; Carbachol; Cocaine; Diphenhydramine; Drug Interactions; Electric Stimulation | 1976 |
Action of the toxic skin secretion of the flatfish Pardachirus marmoratus on the guinea-pig ileum.
Topics: Acetylcholine; Animals; Atropine; Diphenhydramine; Fishes; Guinea Pigs; Hexamethonium Compounds; Ile | 1976 |
Comparison of kinin-forming and amidolytic activities of four trimucases, oedema-producing and kinin-releasing enzymes, from Trimeresurus mucrosquamatus venom.
Topics: Amides; Animals; Aspirin; Crotalid Venoms; Diphenhydramine; Edema; Ileum; Kinins; Methysergide; Musc | 1992 |
Do H3-receptors participate in the effects of histamine on electrically-evoked contractions of rat vas deferens?
Topics: Animals; Betahistine; Diphenhydramine; Electric Stimulation; Histamine; In Vitro Techniques; Male; M | 1991 |
Vasomotor effect of histamine on pig and cattle coronary artery in vitro.
Topics: Animals; Cattle; Cimetidine; Coronary Vessels; Dimaprit; Diphenhydramine; Endothelium, Vascular; His | 1991 |
Involvement of calcium ions in the modulation of electrically-induced rat vas deferens contractions by histaminergic drugs.
Topics: Animals; Calcium; Cimetidine; Dimaprit; Diphenhydramine; Electric Stimulation; Histamine; In Vitro T | 1991 |
Pharmacological screening of Ageratum conyzoides L. (Mentrasto).
Topics: Analgesics; Animals; Anti-Inflammatory Agents; Atropine; Brazil; Diphenhydramine; Drug Evaluation, P | 1991 |
[Effects of cernitin pollen extract (CN-009) on the isolated bladder smooth muscles and the intravesical pressure].
Topics: Aging; Animals; Atropine; Cats; Cimetidine; Diphenhydramine; Dose-Response Relationship, Drug; Drug | 1991 |
Effects of histaminergic drugs on the contractile activity of smooth muscles from imipramine-treated rats.
Topics: Animals; Diphenhydramine; Drug Interactions; Electric Stimulation; Histamine; Imipramine; Male; Musc | 1990 |
Self suppression of phosphoinositide turnover and contraction by stimulating release of endogenous endothelium derived relaxing factor in vascular action of histamine.
Topics: Animals; Calcimycin; Calcium; Cimetidine; Cyclic GMP; Diphenhydramine; Endothelium, Vascular; Histam | 1990 |
Role of serotonin, histamine, and thromboxane A2 in platelet-induced contractions of coronary arteries and aortae from rabbits.
Topics: Animals; Aorta, Thoracic; Aspirin; Blood Platelets; Coronary Vessels; Diphenhydramine; Endothelium, | 1989 |
Histamine relaxation of aortic rings from diabetic rats.
Topics: Animals; Aorta, Thoracic; Diabetes Mellitus, Experimental; Diphenhydramine; Endothelium, Vascular; H | 1989 |
Rocastine (AHR-11325), a rapid acting, nonsedating antihistamine.
Topics: Anaphylaxis; Animals; Astemizole; Azepines; Benzhydryl Compounds; Benzimidazoles; Brompheniramine; C | 1989 |
Effects of morphine and methionine-enkephalin on the smooth muscle tonus and the contraction induced by transmural stimulation in the carp (Cyprinus carpio) intestinal bulb.
Topics: Acetylcholine; Animals; Atropine; Carps; Diphenhydramine; Electric Stimulation; Enkephalin, Methioni | 1986 |
Serotonin, histamine, and norepinephrine mediation of endothelial and vascular smooth muscle cell movement.
Topics: Animals; Aorta; Cattle; Cell Movement; Cells, Cultured; Depression, Chemical; Diphenhydramine; Endot | 1985 |
Histaminergic agents can modulate adrenergic smooth muscle neurotransmission.
Topics: Animals; Diphenhydramine; Electric Stimulation; Histamine; In Vitro Techniques; Male; Muscle Contrac | 1985 |
Inhibition of the platelet activating factor mediated component of guinea pig anaphylaxis by receptor antagonists.
Topics: Alprazolam; Anaphylaxis; Animals; Benzodiazepines; Benzofurans; Benzopyrans; Diphenhydramine; Guinea | 1986 |
Specific reaginic antibody IgG1-induced changes of airway smooth muscle cells.
Topics: Amiloride; Animals; Diphenhydramine; Electric Stimulation; Guinea Pigs; Immunoglobulin G; Male; Memb | 1988 |
In vitro cardiovascular antihistamine properties of cicletanine in comparison with diphenhydramine.
Topics: Animals; Aorta; Diphenhydramine; Diuretics; Guinea Pigs; Heart Rate; Histamine; Histamine Antagonist | 1988 |
Studies of mediator involvement in cooling-induced alterations of guinea pig tracheal smooth muscle contractility.
Topics: Animals; Cold Temperature; Dinoprost; Dinoprostone; Diphenhydramine; Guinea Pigs; Histamine; Male; M | 1988 |
Action on ileal smooth muscle of synthetic detergents and pardaxin.
Topics: Animals; Benzalkonium Compounds; Detergents; Diphenhydramine; Fish Venoms; Guinea Pigs; Ileum; In Vi | 1986 |
Contractile actions of antihistamines on isolated arterial smooth muscle.
Topics: Acetylcholine; Anesthetics, Local; Animals; Aorta, Thoracic; Atropine; Calcium; Chlorpheniramine; Di | 1974 |
Inactivation of prostaglandin E2 by rabbit lung homogenates.
Topics: Animals; Atropine; Diphenhydramine; Female; Hydrogen-Ion Concentration; In Vitro Techniques; Lung; M | 1974 |
Some properties of prostaglandin E1 action on muscle.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Autonomic Agents; Bradykinin; Cats; Decamethonium | 1967 |
Application of drug-receptor theories to angiotensin.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta, Thoracic; Atropine; Cocaine; Diphenhydramine; Dose-Re | 1973 |
Release of prostaglandins from the rabbit renal medulla.
Topics: Angiotensin II; Animals; Atropine; Bradykinin; Carbachol; Diphenhydramine; Dose-Response Relationshi | 1974 |
[Contractile response of the tracheal musculature to various pharmacologic agents].
Topics: Acetylcholine; Animals; Atropine; Barium; Cats; Diphenhydramine; Ganglionic Blockers; Guinea Pigs; H | 1966 |
Pharmacological reactivity of an isolated tracheal preparation of the guinea-pig.
Topics: Acetylcholine; Animals; Atropine; Barium; Chlorisondamine; Chlorpheniramine; Diphenhydramine; Ethano | 1966 |
[Anti-bradykinin action of diphenhydramine on the excised ileum of guinea pigs].
Topics: Animals; Aspirin; Barium; Blood Pressure; Bradykinin; Chlorpheniramine; Diphenhydramine; Ethanol; Gu | 1966 |
A smooth muscle contracting substance in extracts of human umbilical cord.
Topics: Acetylcholine; Angiotensin II; Animals; Atropine; Autacoids; Biological Assay; Blood Pressure; Brady | 1966 |
Pharmacological properties of the proteolytic products of the liver homogenates of rat by the acidic protease (TE-P), isolated from Trametes sanguinea.
Topics: Acetylcholine; Animals; Atropine; Bradykinin; Colon; Cyproheptadine; Diphenhydramine; Duodenum; Fema | 1968 |
Pharmacologic evaluation of a new series of cholinergic antagonists containing an agonist moiety.
Topics: Acetylcholine; Animals; Aorta; Atropine; Benzilates; Carbachol; Chemical Phenomena; Chemistry; Chlor | 1969 |
The effect of calcium depletion on the combination of agonists and competitive antagonists with alpha adrenergic and histaminergic receptors of rabbit aorta.
Topics: Adrenergic alpha-Agonists; Adrenergic alpha-Antagonists; Animals; Aorta; Calcium; Diphenhydramine; F | 1969 |
Comparative in vitro evaluation of cryogenine, cyproheptadine, and diphenhydramine as antagonists of furtrethonium, histamine, and serotonin.
Topics: Alkaloids; Animals; Cyproheptadine; Diphenhydramine; Female; Guinea Pigs; Histamine H1 Antagonists; | 1969 |
Contractile responses of microvascular smooth muscle to antihistamines.
Topics: Animals; Calcium; Capillaries; Chlorpheniramine; Diphenhydramine; Endotoxins; Epinephrine; Female; H | 1970 |
Effects of isoxazolium cations on some isolated muscle preparations.
Topics: Acetylcholine; Angiotensin II; Animals; Aorta; Cholinesterase Inhibitors; Diaphragm; Diphenhydramine | 1971 |
Influence of temperature on recovery of inhibition by antihistaminics and -haloalkylamines toward histamine.
Topics: Animals; Binding Sites; Diphenhydramine; Guinea Pigs; Histamine Antagonists; Histamine H1 Antagonist | 1972 |
[Studies on the perfusion of the isolated human placenta with serotonin and the related substance].
Topics: Acetylcholine; Bradykinin; Diphenhydramine; Epinephrine; Ergotamine; Female; Histamine H1 Antagonist | 1972 |
New compounds: amides derived from ((10,11-dihydro-5H-dibenzo(a,d)cyclohepten-5-yl) thio)acetic acid.
Topics: Acetates; Amides; Animals; Dibenzocycloheptenes; Diphenhydramine; Guinea Pigs; Histamine Antagonists | 1972 |
Inhibitory action of some antihistaminics on the anaphylactic contraction in guinea pig's taenia coli.
Topics: Anaphylaxis; Animals; Antigen-Antibody Reactions; Antigens; Atropine; Barium; Binding, Competitive; | 1972 |
The effects of drugs and treatments upon adrenaline re-reversal in the rabbit.
Topics: Animals; Blood Pressure; Bretylium Compounds; Cocaine; Diphenhydramine; Ear; Epinephrine; Female; Gu | 1974 |
Effects of several macrolide antibiotics on blood pressure of dogs.
Topics: Animals; Anti-Bacterial Agents; Atropine; Biological Assay; Blood Pressure; Cordotomy; Diphenhydrami | 1972 |
Effect on the rat uterus of the venom from the scorpion Leiurus quinquestriatus.
Topics: Animals; Atropine; Chlorpheniramine; Cocaine; Diphenhydramine; Estrus; Female; Hexamethonium Compoun | 1972 |
Influences of diphenhydramine upon the depressant effect of shock plasma on the isolated rabbit papillary muscle.
Topics: Animals; Calcium; Depression, Chemical; Diphenhydramine; Female; Male; Muscle Contraction; Myocardiu | 1973 |
The effects of ketamine on spiral-cut strips of rabbit aorta.
Topics: Animals; Aorta; Diphenhydramine; Dose-Response Relationship, Drug; Histamine; Isoproterenol; Ketamin | 1974 |
Effect of certain drugs on perfused human placenta. X. Norepinephrine release by bradykinin.
Topics: Atropine; Bradykinin; Diphenhydramine; Drug Interactions; Female; Fluorescence; Humans; Muscle Contr | 1972 |
[Effect of the nervous system and its mediators on spontaneous contractile activity of smooth muscle].
Topics: Animals; Autonomic Nervous System; Diphenhydramine; Dogs; Histamine; Male; Muscle Contraction; Muscl | 1972 |
A comparison of the site of action of gastrin I on lower esophageal sphincter and antral circular smooth muscle.
Topics: Acetylcholine; Animals; Atropine; Binding Sites; Culture Techniques; Diphenhydramine; Esophagogastri | 1971 |
[Analysis of the mechanism of kinin-formation in anaphylactic shock].
Topics: Anaphylaxis; Animals; Antigen-Antibody Complex; Aprotinin; Atropine; Bromine; Cyclohexanecarboxylic | 1970 |
Spasmolytic action of 4-methylumbelliferone in isolated guinea-pig's gallbladder.
Topics: Acetylcholine; Animals; Atropine; Barium; Coumarins; Diphenhydramine; Gallbladder; Guinea Pigs; In V | 1971 |
Cardiovascular effects of guanazole.
Topics: Animals; Atropine; Azaguanine; Blood Pressure; Cardiovascular System; Diphenhydramine; Dogs; Electro | 1970 |
Inotropic effects of prostaglandin E2 on isolated cardiac tissue.
Topics: Animals; Atropine; Bretylium Compounds; Diphenhydramine; Heart; Heart Atria; In Vitro Techniques; Mu | 1971 |
Electrophysiological experiments on the action of some partial agonists and their application to receptor theory.
Topics: Acetylcholine; Animals; Atropine; Cecum; Choline; Dibenzylchlorethamine; Diphenhydramine; Electrophy | 1968 |
The role of potassium in ureteral physiology and pharmacology.
Topics: Action Potentials; Animals; Diphenhydramine; Dogs; Epinephrine; Female; Histamine; Isoproterenol; Me | 1968 |
Comparative evaluation of some of the pharmacological actions of Forhistal and Benadryl.
Topics: Acetylcholine; Animals; Anura; Colon; Diaphragm; Dimethindene; Diphenhydramine; Electric Stimulation | 1968 |
Effect of topical drug application to the spinal cord on the scratching movements in cats.
Topics: Aminobutyrates; Animals; Behavior, Animal; Cats; Diphenhydramine; Female; Hexamethonium Compounds; H | 1966 |