Page last updated: 2024-10-26

diphenhydramine and Movement Disorders

diphenhydramine has been researched along with Movement Disorders in 14 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Movement Disorders: Syndromes which feature DYSKINESIAS as a cardinal manifestation of the disease process. Included in this category are degenerative, hereditary, post-infectious, medication-induced, post-inflammatory, and post-traumatic conditions.

Research Excerpts

ExcerptRelevanceReference
"Although diphenhydramine hydrochloride is known to eliminate or reduce the symptoms of dystonia in human patients with acute dystonic reactions and idiopathic torsion dystonia, its mechanism of action is still unclear."3.69Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine. ( Matsumoto, RR; Stone, MR; Truong, DD; van't Groenewout, JL; Vo, VN, 1995)
"Metoclopramide was discontinued and diphenhydramine 50 mg was initially administered intravenously followed with 25 mg orally every 4 hours as needed."1.38Tardive dyskinesia after short-term treatment with oral metoclopramide in an adolescent. ( Karimi Khaledi, M; Shelton, CM; Suda, KJ, 2012)

Research

Studies (14)

TimeframeStudies, this research(%)All Research%
pre-19909 (64.29)18.7374
1990's2 (14.29)18.2507
2000's1 (7.14)29.6817
2010's2 (14.29)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Sawicka, KM1
Goez, H1
Huntsman, RJ1
Karimi Khaledi, M1
Suda, KJ1
Shelton, CM1
FREED, H1
DRAPER, IT1
JOHNS, RJ1
Hermann, DM1
Bassetti, CL1
van't Groenewout, JL1
Stone, MR1
Vo, VN1
Truong, DD1
Matsumoto, RR1
Connor, DF1
Benjamin, S1
Ozbayrak, KR1
Sögtrop, HH1
Weise, HT1
Kirschberg, GJ1
Beitman, BD1
Berk, BZ1
Sananman, ML1
Guggenheim, MA1
Dodge, PR1
Eisenberg, L1

Other Studies

14 other studies available for diphenhydramine and Movement Disorders

ArticleYear
Successful Treatment of Paroxysmal Movement Disorders of Infancy With Dimenhydrinate and Diphenhydramine.
    Pediatric neurology, 2016, Volume: 56

    Topics: Dimenhydrinate; Diphenhydramine; Electroencephalography; Histamine H1 Antagonists; Humans; Infant; M

2016
Tardive dyskinesia after short-term treatment with oral metoclopramide in an adolescent.
    International journal of clinical pharmacy, 2012, Volume: 34, Issue:6

    Topics: Administration, Oral; Adolescent; Age Factors; Antiemetics; Diphenhydramine; Drug Administration Sch

2012
On special uses of diphenhydramine hydrochloride in the somatic therapy ward of a psychiatric hospital.
    The American journal of psychiatry, 1958, Volume: 115, Issue:4

    Topics: Diphenhydramine; Electroconvulsive Therapy; Hospitals, Psychiatric; Humans; Movement Disorders; Naus

1958
THE DISORDERED MOVEMENT IN PARKINSONISM AND THE EFFECT OF DRUG TREATMENT.
    Bulletin of the Johns Hopkins Hospital, 1964, Volume: 115

    Topics: Atropine; Dextroamphetamine; Diphenhydramine; Drug Therapy; Geriatrics; Humans; Kinetics; Motor Skil

1964
Reversible opsoclonus after diphenhydramine misuse.
    European neurology, 2005, Volume: 53, Issue:1

    Topics: Adult; Diphenhydramine; Female; Humans; Hypnotics and Sedatives; Movement Disorders; Ocular Motility

2005
Evidence for the involvement of histamine in the antidystonic effects of diphenhydramine.
    Experimental neurology, 1995, Volume: 134, Issue:2

    Topics: Animals; Diphenhydramine; Disease Models, Animal; Dose-Response Relationship, Drug; Dystonia; Halope

1995
Case study: neuroleptic withdrawal dyskinesia exacerbated by ongoing stimulant treatment.
    Journal of the American Academy of Child and Adolescent Psychiatry, 1995, Volume: 34, Issue:11

    Topics: Antipsychotic Agents; Dextroamphetamine; Diphenhydramine; Fluoxetine; Humans; Male; Mental Disorders

1995
[Results of treatment with DoloVisano for non-specific pain syndrome related to body movement. Concluding report on a field study of 3326 patients by 314 orthopedists].
    Fortschritte der Medizin, 1979, Apr-26, Volume: 97, Issue:16

    Topics: Aspirin; Codeine; Diphenhydramine; Drug Combinations; Drug Evaluation; Humans; Meprobamate; Movement

1979
Dyskinesia-an unusual reaction to ethosuximide.
    Archives of neurology, 1975, Volume: 32, Issue:2

    Topics: Adolescent; Diphenhydramine; Epilepsy, Absence; Ethosuximide; Female; Humans; Movement Disorders

1975
Diphenhydramine in the differential diagnosis of neuroleptic-induced oral-facial dyskinesia.
    The American journal of psychiatry, 1977, Volume: 134, Issue:6

    Topics: Adult; Diagnosis, Differential; Diphenhydramine; Dyskinesia, Drug-Induced; Female; Humans; Movement

1977
Reaction to prochlorperazine?
    Lancet (London, England), 1969, Apr-12, Volume: 1, Issue:7598

    Topics: Adolescent; Child; Diphenhydramine; Female; Humans; Male; Movement Disorders; Prochlorperazine; Spas

1969
Letter: Dyskinesia after fenfluramine.
    The New England journal of medicine, 1974, Aug-22, Volume: 291, Issue:8

    Topics: Adult; Diphenhydramine; Female; Fenfluramine; Humans; Injections, Intravenous; Movement Disorders; T

1974
Unusual arm movements with onset in childhood--a nosologic entity?
    Transactions of the American Neurological Association, 1970, Volume: 95

    Topics: Child; Diagnosis, Differential; Diazepam; Dihydroxyphenylalanine; Diphenhydramine; Dystonia Musculor

1970
The management of the hyperkinetic child.
    Developmental medicine and child neurology, 1966, Volume: 8, Issue:5

    Topics: Child; Child, Preschool; Chlorpromazine; Dextroamphetamine; Diphenhydramine; Environment; Family; Hu

1966