diphenhydramine has been researched along with Motion Sickness in 27 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Motion Sickness: Disorder caused by motion. It includes sea sickness, train sickness, roller coaster rides, rocking chair, hammock swing, car sickness, air sickness, or SPACE MOTION SICKNESS. Symptoms include nausea, vomiting and/or dizziness.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This is an evaluation of the efficacy of metoclopramide (MTCP) or diphenhydramine (DPH) to relieve symptoms of motion sickness in patients being transported via ambulance in a mountainous setting." | 9.15 | Motion sickness: comparison of metoclopramide and diphenhydramine to placebo. ( Andrews, J; Rubio, S; Weichenthal, L, 2011) |
| "Metoclopramide is commonly used to treat vomiting caused by seasickness and acute gastroenteritis on cruise ships and serious adverse effects have not been reported from use at sea." | 7.80 | Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting. ( Dahl, E; Diskin, AL, 2014) |
| "This is an evaluation of the efficacy of metoclopramide (MTCP) or diphenhydramine (DPH) to relieve symptoms of motion sickness in patients being transported via ambulance in a mountainous setting." | 5.15 | Motion sickness: comparison of metoclopramide and diphenhydramine to placebo. ( Andrews, J; Rubio, S; Weichenthal, L, 2011) |
| " Then, we combined it with different doses of psychostimulants (d-amphetamine, modafinil, caffeine) to find the best combination for motion sickness." | 3.83 | The Combination of Scopolamine and Psychostimulants for the Prevention of Severe Motion Sickness. ( Han, B; Liu, AJ; Liu, HQ; Song, XR; Tian, JS; Yu, XH; Zhang, LL; Zhang, Y, 2016) |
| "Metoclopramide is commonly used to treat vomiting caused by seasickness and acute gastroenteritis on cruise ships and serious adverse effects have not been reported from use at sea." | 3.80 | Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting. ( Dahl, E; Diskin, AL, 2014) |
| " We used this rotation-induced pica as a behavioral index of motion sickness in rats and examined whether diphenhydramine, methamphetamine and scopolamine, which are anti-motion sickness drugs for humans, are effective for reducing motion sickness in rats." | 3.67 | Effects of anti-motion sickness drugs on motion sickness in rats. ( Kubo, T; Matsunaga, T; Morita, M; Takeda, N; Wada, H; Yamatodani, A, 1988) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 19 (70.37) | 18.7374 |
| 1990's | 2 (7.41) | 18.2507 |
| 2000's | 1 (3.70) | 29.6817 |
| 2010's | 5 (18.52) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Li, J | 1 |
| Zhang, L | 2 |
| Cheng, X | 1 |
| Shen, B | 1 |
| Qing, C | 1 |
| Fan, G | 1 |
| Dahl, E | 1 |
| Diskin, AL | 1 |
| Shete, RB | 1 |
| Muniswamy, VJ | 1 |
| Pandit, AP | 1 |
| Khandelwal, KR | 1 |
| Zhang, LL | 1 |
| Liu, HQ | 1 |
| Yu, XH | 1 |
| Zhang, Y | 1 |
| Tian, JS | 1 |
| Song, XR | 1 |
| Han, B | 1 |
| Liu, AJ | 1 |
| Rubio, S | 1 |
| Weichenthal, L | 1 |
| Andrews, J | 1 |
| ANTHONISEN, H | 1 |
| JACOBSEN, E | 1 |
| REYMANN, F | 1 |
| CHINN, HI | 3 |
| STRICKLAND, BA | 2 |
| WALTRIP, OH | 3 |
| McGEARY, JD | 1 |
| RETTERSTØL, N | 1 |
| STUART, ED | 1 |
| MILCH, LJ | 1 |
| FRANKL, HD | 1 |
| RENZI, AA | 1 |
| HARMS, AF | 1 |
| FUNCKE, AB | 1 |
| TERSTEEGE, HM | 1 |
| de JONGE, M | 1 |
| NAUTA, WT | 1 |
| GIURGEA, C | 1 |
| MOEYERSOONS, F | 1 |
| VANDERAUWERA, A | 1 |
| BARFOD, B | 1 |
| GAINER, SH | 1 |
| GLASER, EM | 1 |
| HERVEY, GR | 1 |
| McCAWLEY, EL | 1 |
| KULASAVAGE, RJ | 1 |
| WARRINGTON, WR | 1 |
| PASQUESI, TJ | 1 |
| MASSENGALE, HW | 1 |
| WRIGHT, WL | 1 |
| Chan, SW | 1 |
| Rudd, JA | 1 |
| Lin, G | 1 |
| Li, P | 1 |
| Brand, JJ | 2 |
| Scherer, H | 1 |
| Bschorr, J | 1 |
| Takeda, N | 2 |
| Hasegawa, S | 1 |
| Morita, M | 2 |
| Horii, A | 1 |
| Uno, A | 1 |
| Yamatodani, A | 2 |
| Matsunaga, T | 2 |
| Zhabko, EP | 1 |
| Lukomskaia, NIa | 1 |
| Kubo, T | 1 |
| Wada, H | 1 |
| Westin, S | 1 |
| Jaju, BP | 1 |
| Wang, SC | 1 |
3 trials available for diphenhydramine and Motion Sickness
| Article | Year |
|---|---|
Motion sickness: comparison of metoclopramide and diphenhydramine to placebo.
Topics: Diphenhydramine; Double-Blind Method; Humans; Metoclopramide; Motion Sickness; Pain Measurement; Pro | 2011 |
[Considerations about methods to test the effectiveness of anti-vertiginous drugs (author's transl)].
Topics: Atropine; Clinical Trials as Topic; Diphenhydramine; Histamine H1 Antagonists; Humans; Labyrinth Dis | 1980 |
Nelson's eye.
Topics: Clinical Trials as Topic; Diphenhydramine; Drug Evaluation; Humans; Male; Motion Sickness; Vision, O | 1979 |
24 other studies available for diphenhydramine and Motion Sickness
| Article | Year |
|---|---|
Determination of d-amphetamine and diphenhydramine in beagle dog plasma by a 96-well formatted liquid-liquid extraction and capillary zone electrophoresis with field-amplified sample stacking.
Topics: Animals; Calibration; Capsules; Chromatography, High Pressure Liquid; Dextroamphetamine; Diphenhydra | 2018 |
Long-lasting adverse effects after short-term low-dose treatment with metoclopramide for vomiting.
Topics: Adult; Antiemetics; Diphenhydramine; Dyskinesias; Female; Gastroenteritis; Humans; Injections, Intra | 2014 |
Formulation of Eco-friendly Medicated Chewing Gum to Prevent Motion Sickness.
Topics: Administration, Oral; Antiemetics; Calcium Carbonate; Chewing Gum; Diphenhydramine; Drug Carriers; D | 2015 |
The Combination of Scopolamine and Psychostimulants for the Prevention of Severe Motion Sickness.
Topics: Analysis of Variance; Animals; Benzhydryl Compounds; Caffeine; Central Nervous System Stimulants; Ch | 2016 |
[Studies on seasick seamen].
Topics: Diphenhydramine; Humans; Motion Sickness | 1953 |
Prevention of airsickness during training flights.
Topics: Diphenhydramine; Humans; Motion Sickness; Scopolamine | 1953 |
[Seasickness during journey in small vessels].
Topics: Caffeine; Diphenhydramine; Humans; Motion Sickness | 1953 |
Effectiveness of perphenazine and systral against motion sickness.
Topics: Diphenhydramine; Ethylamines; Motion Sickness; Perphenazine; Phenothiazines | 1959 |
Pharmacology of the 2-t-butylbenzhydryl ether of dimethylaminoethanol hydrochloride (BS 6534), a new compound, active against motion sickness.
Topics: Amino Alcohols; Deanol; Diphenhydramine; Ether; Ethers; Humans; Motion Sickness; Salts | 1962 |
ACTION OF SOME ANTI-MOTION SICKNESS DRUGS ON CENTRAL NYSTAGMUS.
Topics: Animals; Anti-Allergic Agents; Brain; Chlorpromazine; Diphenhydramine; Electrophysiology; Histamine | 1963 |
[Amidryl MCO, an effective remedy in seasickness].
Topics: Cephalosporins; Diphenhydramine; Motion Sickness | 1950 |
Prevention of air sickness by benadryl-scopolamine mixtures.
Topics: Biomedical Research; Diphenhydramine; Humans; Motion Sickness; Scopolamine | 1951 |
The prevention of seasickness with hyoscine, benadryl, and phenergan.
Topics: Biomedical Research; Diphenhydramine; Histamine H1 Antagonists; Humans; Motion Sickness; Promethazin | 1951 |
The intravenous use of diphenhydramine hydrochloride in the control of nausea and vomiting.
Topics: Diphenhydramine; Humans; Injections, Intravenous; Motion Sickness; Nausea; Vomiting | 1951 |
Further studies on the effectiveness of various drugs against airsickness.
Topics: Diphenhydramine; Humans; Motion Sickness; Scopolamine | 1951 |
Effectiveness of newer drugs in seasickness.
Topics: Dimenhydrinate; Diphenhydramine; Humans; Motion Sickness | 1950 |
Action of anti-tussive drugs on the emetic reflex of Suncus murinus (house musk shrew).
Topics: Analysis of Variance; Animals; Antiemetics; Antitussive Agents; Baclofen; Cevanes; Codeine; Copper S | 2007 |
Motion sickness and its prevention by drugs.
Topics: Cyclizine; Diphenhydramine; Ear, Inner; Humans; Meclizine; Motion Sickness; Promethazine; Scopolamin | 1967 |
Neuropharmacological mechanisms of emesis. I. Effects of antiemetic drugs on motion- and apomorphine-induced pica in rats.
Topics: Animals; Antiemetics; Apomorphine; Diphenhydramine; Domperidone; Eating; Kaolin; Male; Motion Sickne | 1995 |
[Model of motion sickness in white mice experiments].
Topics: Animals; Antiemetics; Diphenhydramine; Hypnotics and Sedatives; Injections, Intraperitoneal; Male; M | 1997 |
Effects of anti-motion sickness drugs on motion sickness in rats.
Topics: Animals; Diphenhydramine; Kaolin; Male; Methamphetamine; Motion Sickness; Pica; Rats; Rats, Inbred S | 1988 |
[Abuse of travel sickness remedies among young drug addicts].
Topics: Adolescent; Adult; Caffeine; Cannabis; Diphenhydramine; Drug Interactions; Drug Prescriptions; Femal | 1972 |
Effects of diphenhydramine and dimenhydrinate on vestibular neuronal activity of cat: a search for the locus of their antimotion sickness action.
Topics: Animals; Cats; Dimenhydrinate; Diphenhydramine; Electric Stimulation; Evoked Potentials; Motion Sick | 1971 |
A survey of recent motion sickness research.
Topics: Analgesics; Animals; Azocines; Cyclazocine; Diphenhydramine; Guinea Pigs; Humans; Motion Sickness; N | 1970 |