diphenhydramine has been researched along with Methemoglobinemia in 2 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Methemoglobinemia: The presence of methemoglobin in the blood, resulting in cyanosis. A small amount of methemoglobin is present in the blood normally, but injury or toxic agents convert a larger proportion of hemoglobin into methemoglobin, which does not function reversibly as an oxygen carrier. Methemoglobinemia may be due to a defect in the enzyme NADH methemoglobin reductase (an autosomal recessive trait) or to an abnormality in hemoglobin M (an autosomal dominant trait). (Dorland, 27th ed)
| Excerpt | Relevance | Reference |
|---|---|---|
| "Dapsone is a leprostatic agent commonly prescribed for the treatment of patients with leprosy, malaria, and a variety of blistering skin diseases, including dermatitis herpetiformis." | 5.36 | Pathophysiologic mechanisms, diagnosis, and management of dapsone-induced methemoglobinemia. ( Ashurst, JV; Fritz, WT; Hauger, W; Wasson, MN, 2010) |
| "Dapsone is a leprostatic agent commonly prescribed for the treatment of patients with leprosy, malaria, and a variety of blistering skin diseases, including dermatitis herpetiformis." | 1.36 | Pathophysiologic mechanisms, diagnosis, and management of dapsone-induced methemoglobinemia. ( Ashurst, JV; Fritz, WT; Hauger, W; Wasson, MN, 2010) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (50.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 1 (50.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ashurst, JV | 1 |
| Wasson, MN | 1 |
| Hauger, W | 1 |
| Fritz, WT | 1 |
| Kalow, W | 1 |
1 review available for diphenhydramine and Methemoglobinemia
| Article | Year |
|---|---|
Ethnic differences in reactions to drugs and xenobiotics. Caffeine and other drugs.
Topics: Acetylation; Caffeine; Cytochrome P-450 Enzyme System; Diphenhydramine; Drug-Related Side Effects an | 1986 |
1 other study available for diphenhydramine and Methemoglobinemia
| Article | Year |
|---|---|
Pathophysiologic mechanisms, diagnosis, and management of dapsone-induced methemoglobinemia.
Topics: Aged; Anti-Allergic Agents; Dapsone; Dermatitis, Contact; Diphenhydramine; Female; Histamine H1 Anta | 2010 |