diphenhydramine has been researched along with Metabolic Acidosis in 4 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "We describe a patient who had consumed large quantities of a proprietary cough mixture containing diphenhydramine, ammonium chloride and sodium citrate (Benylin expectorant) daily for several months and subsequently presented with confusion, marked metabolic acidosis and non-ketotic hyperglycaemia." | 3.67 | Benylin dependence, metabolic acidosis and hyperglycaemia. ( Goodwin, K; MacRury, S; Neilson, R, 1987) |
| "This report describes an unexpected adverse effect in three children receiving teniposide at 3-5 times the conventional dosage (i." | 1.28 | Somnolence, hypotension, and metabolic acidosis following high-dose teniposide treatment in children with leukemia. ( Baker, DK; McLeod, HL; Pui, CH; Rodman, JH, 1991) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 2 (50.00) | 18.7374 |
| 1990's | 1 (25.00) | 18.2507 |
| 2000's | 1 (25.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Kamijo, Y | 1 |
| Soma, K | 1 |
| Sato, C | 1 |
| Kurihara, K | 1 |
| McLeod, HL | 1 |
| Baker, DK | 1 |
| Pui, CH | 1 |
| Rodman, JH | 1 |
| MacRury, S | 1 |
| Neilson, R | 1 |
| Goodwin, K | 1 |
| Martin, DS | 1 |
| Kurzweg, FT | 1 |
| Amor, RL | 1 |
| Harvey, R | 1 |
| Daigle, L | 1 |
4 other studies available for diphenhydramine and Metabolic Acidosis
| Article | Year |
|---|---|
Fatal diphenhydramine poisoning with increased vascular permeability including late pulmonary congestion refractory to percutaneous cardiovascular support.
Topics: Acidosis; Adult; Capillary Permeability; Dehydration; Diphenhydramine; Fatal Outcome; Histamine H1 A | 2008 |
Somnolence, hypotension, and metabolic acidosis following high-dose teniposide treatment in children with leukemia.
Topics: Acidosis; Antineoplastic Combined Chemotherapy Protocols; Child; Child, Preschool; Cytarabine; Diphe | 1991 |
Benylin dependence, metabolic acidosis and hyperglycaemia.
Topics: Acidosis; Aged; Ammonium Chloride; Diphenhydramine; Expectorants; Humans; Hyperglycemia; Male; Subst | 1987 |
Multiantagonist and volume therapy for late endotoxin shock.
Topics: Acidosis; Aminocaproates; Animals; Aprotinin; Bicarbonates; Cyproheptadine; Diphenhydramine; Dogs; E | 1966 |