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diphenhydramine and Mast Cell Activation Disease

diphenhydramine has been researched along with Mast Cell Activation Disease in 4 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Research Excerpts

ExcerptRelevanceReference
"Mastocytosis is an accumulation of clonal mast cells within tissues, commonly caused by mutations in the KIT proto-oncogene."2.61Management of a neonate with diffuse cutaneous mastocytosis: Case report and literature review. ( Carter, MC; Diaz, LZ; Jenkinson, HA; Levy, ML; Lundgren, AD, 2019)
"Dyspareunia, vaginitis and dysfunctional uterine bleeding (DUB) are common problems which, despite their polygenicity, commonly appear idiopathic and treatment-refractory."1.51Successful mast-cell-targeted treatment of chronic dyspareunia, vaginitis, and dysfunctional uterine bleeding. ( Afrin, LB; Dempsey, TT; Dorff, SR; Rosenthal, LS, 2019)
"Continuous diphenhydramine infusion can provide promising outcomes following the failure of intermittent antihistamine dosing in patients with severe mast cell activation syndrome."1.46Continuous diphenhydramine infusion and imatinib for KIT-D816V-negative mast cell activation syndrome: a case report. ( Ali, N; Boigon, M; Fidler, C; Ghani, A; Hamid, M; Jafri, SIM; Malik, F, 2017)

Research

Studies (4)

TimeframeStudies, this research(%)All Research%
pre-19901 (25.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's3 (75.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Malik, F1
Ali, N1
Jafri, SIM1
Ghani, A1
Hamid, M1
Boigon, M1
Fidler, C1
Jenkinson, HA1
Lundgren, AD1
Carter, MC1
Diaz, LZ1
Levy, ML1
Afrin, LB1
Dempsey, TT1
Rosenthal, LS1
Dorff, SR1
Jacoby, BG1
Wesley, RE1

Reviews

1 review available for diphenhydramine and Mast Cell Activation Disease

ArticleYear
Management of a neonate with diffuse cutaneous mastocytosis: Case report and literature review.
    Pediatric dermatology, 2019, Volume: 36, Issue:4

    Topics: Cetirizine; Diphenhydramine; Drug Therapy, Combination; Gene Expression Regulation, Developmental; H

2019

Other Studies

3 other studies available for diphenhydramine and Mast Cell Activation Disease

ArticleYear
Continuous diphenhydramine infusion and imatinib for KIT-D816V-negative mast cell activation syndrome: a case report.
    Journal of medical case reports, 2017, Apr-24, Volume: 11, Issue:1

    Topics: Adolescent; Diphenhydramine; Female; Histamine H1 Antagonists; Humans; Imatinib Mesylate; Infusions,

2017
Successful mast-cell-targeted treatment of chronic dyspareunia, vaginitis, and dysfunctional uterine bleeding.
    Journal of obstetrics and gynaecology : the journal of the Institute of Obstetrics and Gynaecology, 2019, Volume: 39, Issue:5

    Topics: Administration, Topical; Adult; Anti-Allergic Agents; Anti-Asthmatic Agents; Cromolyn Sodium; Diphen

2019
Painful orbital inflammatory lesions and mastocytosis.
    Annals of ophthalmology, 1987, Volume: 19, Issue:4

    Topics: Adolescent; Biopsy; Cimetidine; Clemastine; Combined Modality Therapy; Diphenhydramine; Drug Therapy

1987