diphenhydramine has been researched along with Local Neoplasm Recurrence in 7 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The present study investigated the efficacy and safety of weekly administration of paclitaxel (PTX) for 37 patients with advanced or recurrent breast cancer." | 9.12 | [A phase II study of weekly paclitaxel for advanced or recurrent breast cancer]. ( Imai, S; Jitsuko, A; Nishikawa, H; Otoshi, M; Takahara, S; Tsubono, M; Wada, Y, 2007) |
| "The present study investigated the efficacy and safety of weekly administration of paclitaxel (PTX) for 37 patients with advanced or recurrent breast cancer." | 5.12 | [A phase II study of weekly paclitaxel for advanced or recurrent breast cancer]. ( Imai, S; Jitsuko, A; Nishikawa, H; Otoshi, M; Takahara, S; Tsubono, M; Wada, Y, 2007) |
| "Background Carboplatin-based chemotherapy offers high response rates and improved overall survival for women with epithelial ovarian cancer, but its use is limited by the occurrence of hypersensitivity reactions." | 3.88 | Prevention of carboplatin-induced hypersensitivity reactions in women with ovarian cancer. ( Bulter, M; Deghan Manshadi, S; Jerzak, KJ; Mackay, HJ; Maganti, M; McCuaig, JM; Ng, P; Oza, A, 2018) |
| "Five patients with recurrent ovarian cancer who had a previous documented hypersensitivity reaction to carboplatin and a good clinical indication for continuing treatment with platinum were retreated following cisplatin desensitisation." | 2.71 | Carboplatin hypersensitivity reactions: re-treatment with cisplatin desensitisation. ( Friedlander, M; Jones, R; Ryan, M, 2003) |
| " One patient experienced a life-threatening adverse reaction within minutes of receiving the first dose." | 1.31 | Pegylated liposomal doxorubicin: tolerability and toxicity. ( Goram, AL; Richmond, PL, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 6 (85.71) | 29.6817 |
| 2010's | 1 (14.29) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Jerzak, KJ | 1 |
| Deghan Manshadi, S | 1 |
| Ng, P | 1 |
| Maganti, M | 1 |
| McCuaig, JM | 1 |
| Bulter, M | 1 |
| Oza, A | 1 |
| Mackay, HJ | 1 |
| Jones, R | 1 |
| Ryan, M | 1 |
| Friedlander, M | 1 |
| Egawa, T | 1 |
| Kubota, T | 1 |
| Nagashima, A | 1 |
| Doi, M | 1 |
| Kitano, M | 1 |
| Hayashi, S | 1 |
| Yoshii, H | 1 |
| Saikawa, Y | 1 |
| Kitajima, M | 1 |
| Terauchi, F | 1 |
| Nagashima, T | 1 |
| Kobayashi, Y | 1 |
| Yamamoto, Y | 1 |
| Moritake, T | 1 |
| Seiki, T | 1 |
| Ogura, H | 1 |
| Wada, Y | 1 |
| Otoshi, M | 1 |
| Jitsuko, A | 1 |
| Nishikawa, H | 1 |
| Takahara, S | 1 |
| Tsubono, M | 1 |
| Imai, S | 1 |
| Goram, AL | 1 |
| Richmond, PL | 1 |
| Uno, Y | 1 |
| Hirano, M | 1 |
| Murakami, N | 1 |
| Kikuchi, T | 1 |
| Nozawa, H | 1 |
| Okuda, T | 1 |
| Oya, J | 1 |
| Kikkawa, H | 1 |
3 trials available for diphenhydramine and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Carboplatin hypersensitivity reactions: re-treatment with cisplatin desensitisation.
Topics: Antineoplastic Agents; Carboplatin; Cisplatin; Dexamethasone; Diphenhydramine; Drug Hypersensitivity | 2003 |
[A phase II study of weekly paclitaxel for advanced or recurrent breast cancer].
Topics: Adult; Aged; Alopecia; Antiemetics; Antineoplastic Agents, Phytogenic; Bone Neoplasms; Breast Neopla | 2007 |
[Weekly administration of low-dose paclitaxel for advanced or metastatic breast cancer].
Topics: Aged; Alopecia; Antineoplastic Agents, Phytogenic; Breast Neoplasms; Dexamethasone; Diphenhydramine; | 2002 |
4 other studies available for diphenhydramine and Local Neoplasm Recurrence
| Article | Year |
|---|---|
Prevention of carboplatin-induced hypersensitivity reactions in women with ovarian cancer.
Topics: Adult; Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Carboplatin; Carcino | 2018 |
[Usefulness of weekly administration of paclitaxel for advanced or recurrent gastric cancer].
Topics: Adult; Aged; Antiemetics; Antineoplastic Agents, Phytogenic; Dexamethasone; Diphenhydramine; Drug Ad | 2004 |
A pilot study of weekly paclitaxel administration for patients with relapsed cervical cancer after heavy medication.
Topics: Agranulocytosis; Alopecia; Antiemetics; Antineoplastic Agents, Phytogenic; Cimetidine; Combined Moda | 2005 |
Pegylated liposomal doxorubicin: tolerability and toxicity.
Topics: Aged; Aged, 80 and over; Antineoplastic Combined Chemotherapy Protocols; Dexamethasone; Diphenhydram | 2001 |