diphenhydramine has been researched along with Light Sensitivity in 1 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Timeframe | Studies, this research(%) | All Research% |
---|---|---|
pre-1990 | 0 (0.00) | 18.7374 |
1990's | 0 (0.00) | 18.2507 |
2000's | 0 (0.00) | 29.6817 |
2010's | 0 (0.00) | 24.3611 |
2020's | 1 (100.00) | 2.80 |
Authors | Studies |
---|---|
Cohen, F | 1 |
Friedman, BW | 1 |
Trial | Phase | Enrollment | Study Type | Start Date | Status | ||
---|---|---|---|---|---|---|---|
Hydromorphone Versus Prochlorperazine + Diphenhydramine for Treatment of Acute Migraine. A Randomized, Emergency Department Based, Comparative Efficacy Study[NCT02389829] | Phase 4 | 127 participants (Actual) | Interventional | 2015-03-31 | Completed | ||
[information is prepared from clinicaltrials.gov, extracted Sep-2024] |
Data collected by telephone. Patients were asked if they needed additional medication after discharge in order to reduce level of pain. This additional medication is considered rescue medication. (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department
Intervention | Participants (Count of Participants) |
---|---|
Hydromorphone | 23 |
Prochlorperazine | 4 |
Participants were asked to evaluate pain status since discharge. Participants who achieved total headache freedom for at least 1 hour are considered to achieve short term headache relief. (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department
Intervention | Participants (Count of Participants) |
---|---|
Hydromorphone | 16 |
Prochlorperazine | 29 |
"Participants were asked to make evaluation of pain status since discharge. Those achieving headache level mild or none for 1 hour are considered to achieve short term headache relief." (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department
Intervention | Participants (Count of Participants) |
---|---|
Hydromorphone | 33 |
Prochlorperazine | 53 |
"Sustained headache relief is defined as achieving a headache level of mild or none within two hours and maintaining a level of mild or none for 48 hours, without use of addition medication. Patient self-evaluated pain level is solicited every half hour for two hours in the Emergency Department and then by telephone 48 hours after medication administration." (NCT02389829)
Timeframe: up to 2 hours in Emergency Department, 48 hours after discharge from Emergency Department
Intervention | Participants (Count of Participants) |
---|---|
Hydromorphone | 20 |
Prochlorperazine | 37 |
1 trial available for diphenhydramine and Light Sensitivity
Article | Year |
---|---|
A randomized study of IV prochlorperazine plus diphenhydramine versus IV hydromorphone for migraine-associated symptoms: A post hoc analysis.
Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Antiemetics; Diphenhydramine; Double-Blind M | 2021 |