Page last updated: 2024-10-26

diphenhydramine and Light Sensitivity

diphenhydramine has been researched along with Light Sensitivity in 1 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Research

Studies (1)

TimeframeStudies, this research(%)All Research%
pre-19900 (0.00)18.7374
1990's0 (0.00)18.2507
2000's0 (0.00)29.6817
2010's0 (0.00)24.3611
2020's1 (100.00)2.80

Authors

AuthorsStudies
Cohen, F1
Friedman, BW1

Clinical Trials (1)

Trial Overview

TrialPhaseEnrollmentStudy TypeStart DateStatus
Hydromorphone Versus Prochlorperazine + Diphenhydramine for Treatment of Acute Migraine. A Randomized, Emergency Department Based, Comparative Efficacy Study[NCT02389829]Phase 4127 participants (Actual)Interventional2015-03-31Completed
[information is prepared from clinicaltrials.gov, extracted Sep-2024]

Trial Outcomes

Number of Participants Needing Rescue Medication as Assessed by Questionnaire

Data collected by telephone. Patients were asked if they needed additional medication after discharge in order to reduce level of pain. This additional medication is considered rescue medication. (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department

InterventionParticipants (Count of Participants)
Hydromorphone23
Prochlorperazine4

Number of Participants Who Achieved Short Term Headache Freedom; Assessed by Telephone Questionnaire

Participants were asked to evaluate pain status since discharge. Participants who achieved total headache freedom for at least 1 hour are considered to achieve short term headache relief. (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department

InterventionParticipants (Count of Participants)
Hydromorphone16
Prochlorperazine29

Number of Participants Who Achieved Short Term Headache Relief, Assessed by Telphone Questionnaire

"Participants were asked to make evaluation of pain status since discharge. Those achieving headache level mild or none for 1 hour are considered to achieve short term headache relief." (NCT02389829)
Timeframe: 48 hours after discharge from Emergency Department

InterventionParticipants (Count of Participants)
Hydromorphone33
Prochlorperazine53

Number of Participants With Sustained Headache Relief Assessed by Self-evaluation

"Sustained headache relief is defined as achieving a headache level of mild or none within two hours and maintaining a level of mild or none for 48 hours, without use of addition medication. Patient self-evaluated pain level is solicited every half hour for two hours in the Emergency Department and then by telephone 48 hours after medication administration." (NCT02389829)
Timeframe: up to 2 hours in Emergency Department, 48 hours after discharge from Emergency Department

InterventionParticipants (Count of Participants)
Hydromorphone20
Prochlorperazine37

Trials

1 trial available for diphenhydramine and Light Sensitivity

ArticleYear
A randomized study of IV prochlorperazine plus diphenhydramine versus IV hydromorphone for migraine-associated symptoms: A post hoc analysis.
    Headache, 2021, Volume: 61, Issue:8

    Topics: Administration, Intravenous; Adult; Analgesics, Opioid; Antiemetics; Diphenhydramine; Double-Blind M

2021