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diphenhydramine and Ischemia

diphenhydramine has been researched along with Ischemia in 7 studies

Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.

Ischemia: A hypoperfusion of the BLOOD through an organ or tissue caused by a PATHOLOGIC CONSTRICTION or obstruction of its BLOOD VESSELS, or an absence of BLOOD CIRCULATION.

Research Excerpts

ExcerptRelevanceReference
"Indomethacin can reduce the microvascular permeability induced by repeated ischemia."7.67The effect of antihistamines and indomethacin on microvascular permeability changes due to repeated pressure-induced local ischemia. ( Ehira, T; Romanus, M, 1988)
"Indomethacin can reduce the microvascular permeability induced by repeated ischemia."3.67The effect of antihistamines and indomethacin on microvascular permeability changes due to repeated pressure-induced local ischemia. ( Ehira, T; Romanus, M, 1988)
" The osmotic reflection coefficient for total plasma proteins and isogravimetric capillary pressure were estimated in canine gracilis muscle for the following conditions: control, ischemia, and ischemia plus pretreatment with allopurinol (a xanthine oxidase inhibitor), catalase (a peroxidase that reduces hydrogen peroxide to water and molecular oxygen), superoxide dismutase (a superoxide anion scavenger), dimethyl sulfoxide (a hydroxyl radical scavenger), diphenhydramine (a histamine H1-receptor blocker), or cimetidine (a histamine H2-receptor blocker)."3.67The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability. ( Granger, DN; Korthuis, RJ; Taylor, AE; Townsley, MI, 1985)

Research

Studies (7)

TimeframeStudies, this research(%)All Research%
pre-19905 (71.43)18.7374
1990's1 (14.29)18.2507
2000's1 (14.29)29.6817
2010's0 (0.00)24.3611
2020's0 (0.00)2.80

Authors

AuthorsStudies
Jacob, E1
Miaskowski, C1
Savedra, M1
Beyer, JE1
Treadwell, M1
Styles, L1
STEIN, ID1
MACAULAY, AI1
Ermolaev, VL1
Burleva, EP1
Eppihimer, MJ1
Russell, J1
Anderson, DC1
Epstein, CJ1
Laroux, S1
Granger, DN2
Ehira, T1
Romanus, M1
Korthuis, RJ1
Townsley, MI1
Taylor, AE1
Hinshaw, LB1
Page, BB1
Brake, CM1
Emerson, TE1

Other Studies

7 other studies available for diphenhydramine and Ischemia

ArticleYear
Management of vaso-occlusive pain in children with sickle cell disease.
    Journal of pediatric hematology/oncology, 2003, Volume: 25, Issue:4

    Topics: Adolescent; Adult; Analgesia, Patient-Controlled; Analgesics, Opioid; Anemia, Sickle Cell; Anti-Infl

2003
CONTROL OF PAIN IN CERTAIN PERIPHERAL VASCULAR DISORDERS.
    New York state journal of medicine, 1964, Jul-15, Volume: 64

    Topics: Analgesics; Analgesics, Non-Narcotic; Antipyretics; Diphenhydramine; Drug Therapy; Foot Diseases; Ge

1964
[Transcatheteral intra-arterial infusion of drug mixtures in the treatment of severe ischemia of the lower limbs].
    Vestnik khirurgii imeni I. I. Grekova, 1982, Volume: 129, Issue:11

    Topics: Acetylcholine; Adult; Aged; Catheterization; Dextrans; Diphenhydramine; Drug Combinations; Female; H

1982
Modulation of P-selectin expression in the postischemic intestinal microvasculature.
    The American journal of physiology, 1997, Volume: 273, Issue:6

    Topics: Animals; Antibodies, Monoclonal; Diphenhydramine; Intestine, Small; Ischemia; Male; Mast Cells; Mice

1997
The effect of antihistamines and indomethacin on microvascular permeability changes due to repeated pressure-induced local ischemia.
    Acta chirurgica Scandinavica, 1988, Volume: 154, Issue:1

    Topics: Animals; Capillary Permeability; Cricetinae; Diphenhydramine; Histamine H1 Antagonists; Histamine H2

1988
The role of oxygen-derived free radicals in ischemia-induced increases in canine skeletal muscle vascular permeability.
    Circulation research, 1985, Volume: 57, Issue:4

    Topics: Allopurinol; Animals; Blood Flow Velocity; Blood Pressure; Capillaries; Capillary Permeability; Cata

1985
Mechanisms of intrarenal hemodynamic changes following acute arterial occlusion.
    The American journal of physiology, 1963, Volume: 205, Issue:5

    Topics: Angiotensin II; Animals; Blood Pressure; Diphenhydramine; Dogs; Epinephrine; Hemodynamics; Histamine

1963