diphenhydramine has been researched along with Hypoglycemia in 3 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Hypoglycemia: A syndrome of abnormally low BLOOD GLUCOSE level. Clinical hypoglycemia has diverse etiologies. Severe hypoglycemia eventually lead to glucose deprivation of the CENTRAL NERVOUS SYSTEM resulting in HUNGER; SWEATING; PARESTHESIA; impaired mental function; SEIZURES; COMA; and even DEATH.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gatifloxacin, a fluoroquinolone antimicrobial agent, has been reported to cause both hypoglycemia and hyperglycemia in diabetic and non-diabetic patients." | 7.76 | Gatifloxacin-induced histamine release and hyperglycemia in rats. ( Ishiwata, Y; Yasuhara, M, 2010) |
| "Gatifloxacin, a fluoroquinolone antimicrobial agent, has been reported to cause both hypoglycemia and hyperglycemia in diabetic and non-diabetic patients." | 3.76 | Gatifloxacin-induced histamine release and hyperglycemia in rats. ( Ishiwata, Y; Yasuhara, M, 2010) |
| " Diphenhydramine (1 mg/kg) antagonized the hyperglycemia induced by 300 mg/kg of levofloxacin." | 3.73 | Effect of levofloxacin on serum glucose concentration in rats. ( Ishiwata, Y; Itoga, Y; Yasuhara, M, 2006) |
| " In our patient, a 34-year-old man with poorly controlled type 1 diabetes and autonomic neuropathy manifested by postural hypotension and diarrhea, treatment with diphenhydramine and cimetidine (H1 and H2 histamine antagonists, respectively) markedly improved the hypotension and diarrhea and led to better blood glucose control." | 3.66 | Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy. ( Robertson, D; Stacpoole, PW, 1982) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Ishiwata, Y | 2 |
| Yasuhara, M | 2 |
| Itoga, Y | 1 |
| Stacpoole, PW | 1 |
| Robertson, D | 1 |
3 other studies available for diphenhydramine and Hypoglycemia
| Article | Year |
|---|---|
Gatifloxacin-induced histamine release and hyperglycemia in rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Blood Glucose; Diabetes Mellitus, Experimental | 2010 |
Effect of levofloxacin on serum glucose concentration in rats.
Topics: Adrenal Medulla; Animals; Anti-Bacterial Agents; Blood Glucose; Diphenhydramine; Dose-Response Relat | 2006 |
Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy.
Topics: Adult; Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Drug Therapy, Combination; Hist | 1982 |