diphenhydramine has been researched along with Hyperglycemia, Postprandial in 11 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Hyperglycemia, Postprandial: Abnormally high BLOOD GLUCOSE level after a meal.
| Excerpt | Relevance | Reference |
|---|---|---|
| "Gatifloxacin, a fluoroquinolone antimicrobial agent, has been reported to cause both hypoglycemia and hyperglycemia in diabetic and non-diabetic patients." | 7.76 | Gatifloxacin-induced histamine release and hyperglycemia in rats. ( Ishiwata, Y; Yasuhara, M, 2010) |
| "This Phase II trial was designed to evaluate the overall objective response rate, complete response rate, efficacy, and safety of weekly paclitaxel (Taxol) and carboplatin (Paraplatin) in the treatment of advanced urothelial carcinoma." | 5.11 | A phase II evaluation of weekly paclitaxel plus carboplatin in advanced urothelial cancer. ( Asmar, L; Dakhil, S; Friedland, DM; Gregurich, MA; Hollen, C, 2004) |
| "Gatifloxacin, a fluoroquinolone antimicrobial agent, has been reported to cause both hypoglycemia and hyperglycemia in diabetic and non-diabetic patients." | 3.76 | Gatifloxacin-induced histamine release and hyperglycemia in rats. ( Ishiwata, Y; Yasuhara, M, 2010) |
| " Diphenhydramine (1 mg/kg) antagonized the hyperglycemia induced by 300 mg/kg of levofloxacin." | 3.73 | Effect of levofloxacin on serum glucose concentration in rats. ( Ishiwata, Y; Itoga, Y; Yasuhara, M, 2006) |
| "We studied the effects of the histamine H1 receptor antagonists diphenhydramine and pyrilamine, the H2 receptor antagonist ranitidine and the muscarinic receptor antagonist atropine injected into the third cerebral ventricle on prostaglandin F2 alpha (PGF2 alpha)-induced hyperglycemia in anesthetized fed rats." | 3.68 | Involvement of central cholinergic muscarinic receptors and histamine H1 receptors in hyperglycemia induced by prostaglandin F2 alpha in rats. ( Iguchi, A; Kunoh, Y; Nonogaki, K; Sakamoto, N; Tamagawa, T; Zhu, LX, 1993) |
| "We describe a patient who had consumed large quantities of a proprietary cough mixture containing diphenhydramine, ammonium chloride and sodium citrate (Benylin expectorant) daily for several months and subsequently presented with confusion, marked metabolic acidosis and non-ketotic hyperglycaemia." | 3.67 | Benylin dependence, metabolic acidosis and hyperglycaemia. ( Goodwin, K; MacRury, S; Neilson, R, 1987) |
| " In our patient, a 34-year-old man with poorly controlled type 1 diabetes and autonomic neuropathy manifested by postural hypotension and diarrhea, treatment with diphenhydramine and cimetidine (H1 and H2 histamine antagonists, respectively) markedly improved the hypotension and diarrhea and led to better blood glucose control." | 3.66 | Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy. ( Robertson, D; Stacpoole, PW, 1982) |
| "Temsirolimus (CCI-779) is a novel inhibitor of the mammalian target of rapamycin." | 2.75 | A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors. ( Fujisaka, Y; Horiike, A; Tamura, T; Yamada, Y; Yamamoto, N, 2010) |
| "Glycogen was depleted only by amphetamine-like compounds or by bemegride-induced convulsions." | 1.25 | Physiological and drug-induced changes in the glycogen content of mouse brain. ( Hutchins, DA; Rogers, KJ, 1970) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 5 (45.45) | 18.7374 |
| 1990's | 1 (9.09) | 18.2507 |
| 2000's | 3 (27.27) | 29.6817 |
| 2010's | 2 (18.18) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fujisaka, Y | 1 |
| Yamada, Y | 1 |
| Yamamoto, N | 1 |
| Horiike, A | 1 |
| Tamura, T | 1 |
| Ishiwata, Y | 2 |
| Yasuhara, M | 2 |
| Nagai, K | 2 |
| Niijima, A | 1 |
| Yamano, T | 1 |
| Otani, H | 1 |
| Okumra, N | 1 |
| Tsuruoka, N | 1 |
| Nakai, M | 1 |
| Kiso, Y | 1 |
| Friedland, DM | 1 |
| Dakhil, S | 1 |
| Hollen, C | 1 |
| Gregurich, MA | 1 |
| Asmar, L | 1 |
| Itoga, Y | 1 |
| Stacpoole, PW | 1 |
| Robertson, D | 1 |
| Nonogaki, K | 1 |
| Iguchi, A | 1 |
| Zhu, LX | 1 |
| Kunoh, Y | 1 |
| Tamagawa, T | 1 |
| Sakamoto, N | 1 |
| Frohman, LA | 1 |
| MacRury, S | 1 |
| Neilson, R | 1 |
| Goodwin, K | 1 |
| Dimlich, RV | 1 |
| Hutchins, DA | 1 |
| Rogers, KJ | 1 |
2 trials available for diphenhydramine and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
A Phase 1 clinical study of temsirolimus (CCI-779) in Japanese patients with advanced solid tumors.
Topics: Adult; Aged; Anti-Allergic Agents; Antineoplastic Agents; Area Under Curve; Carcinoma, Renal Cell; C | 2010 |
A phase II evaluation of weekly paclitaxel plus carboplatin in advanced urothelial cancer.
Topics: Adult; Aged; Aged, 80 and over; Anti-Ulcer Agents; Antineoplastic Combined Chemotherapy Protocols; A | 2004 |
9 other studies available for diphenhydramine and Hyperglycemia, Postprandial
| Article | Year |
|---|---|
Gatifloxacin-induced histamine release and hyperglycemia in rats.
Topics: Administration, Oral; Animals; Anti-Infective Agents; Blood Glucose; Diabetes Mellitus, Experimental | 2010 |
Possible role of L-carnosine in the regulation of blood glucose through controlling autonomic nerves.
Topics: Animals; Autonomic Pathways; Blood Glucose; Carnosine; Deoxyglucose; Diabetes Mellitus, Experimental | 2003 |
Effect of levofloxacin on serum glucose concentration in rats.
Topics: Adrenal Medulla; Animals; Anti-Bacterial Agents; Blood Glucose; Diphenhydramine; Dose-Response Relat | 2006 |
Combination H1 and H2 receptor antagonist therapy in diabetic autonomic neuropathy.
Topics: Adult; Cimetidine; Diabetic Neuropathies; Diarrhea; Diphenhydramine; Drug Therapy, Combination; Hist | 1982 |
Involvement of central cholinergic muscarinic receptors and histamine H1 receptors in hyperglycemia induced by prostaglandin F2 alpha in rats.
Topics: Animals; Atropine; Dinoprost; Diphenhydramine; Histamine H1 Antagonists; Hyperglycemia; Injections, | 1993 |
Neurotensin hyperglycemia:evidence for histamine mediation and the assessment of a possible physiologic role.
Topics: Animals; Blood Glucose; Cimetidine; Diphenhydramine; Glucagon; Histamine; Hyperglycemia; Insulin; Ma | 1978 |
Benylin dependence, metabolic acidosis and hyperglycaemia.
Topics: Acidosis; Aged; Ammonium Chloride; Diphenhydramine; Expectorants; Humans; Hyperglycemia; Male; Subst | 1987 |
Histamine antagonists in the treatment of shock hyperglycemia in the rat.
Topics: Animals; Blood Glucose; Blood Pressure; Diphenhydramine; Drug Therapy, Combination; Histamine; Hyper | 1985 |
Physiological and drug-induced changes in the glycogen content of mouse brain.
Topics: Amphetamine; Animals; Bemegride; Body Temperature; Brain Chemistry; Caffeine; Catecholamines; Circad | 1970 |