diphenhydramine has been researched along with Hepatic Encephalopathy in 3 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Hepatic Encephalopathy: A syndrome characterized by central nervous system dysfunction in association with LIVER FAILURE, including portal-systemic shunts. Clinical features include lethargy and CONFUSION (frequently progressing to COMA); ASTERIXIS; NYSTAGMUS, PATHOLOGIC; brisk oculovestibular reflexes; decorticate and decerebrate posturing; MUSCLE SPASTICITY; and bilateral extensor plantar reflexes (see REFLEX, BABINSKI). ELECTROENCEPHALOGRAPHY may demonstrate triphasic waves. (From Adams et al., Principles of Neurology, 6th ed, pp1117-20; Plum & Posner, Diagnosis of Stupor and Coma, 3rd ed, p222-5)
| Excerpt | Relevance | Reference |
|---|---|---|
| " In cases of massive acetaminophen overdose, standard acetylcysteine dosing may not be adequate." | 5.37 | Hepatic failure despite early acetylcysteine following large acetaminophen-diphenhydramine overdose. ( Bagdure, D; Heard, K; Monte, A; Wang, GS, 2011) |
| " In cases of massive acetaminophen overdose, standard acetylcysteine dosing may not be adequate." | 1.37 | Hepatic failure despite early acetylcysteine following large acetaminophen-diphenhydramine overdose. ( Bagdure, D; Heard, K; Monte, A; Wang, GS, 2011) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 1 (33.33) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (33.33) | 29.6817 |
| 2010's | 1 (33.33) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Fridman, V | 1 |
| Galetta, SL | 1 |
| Pruitt, AA | 1 |
| Levine, JM | 1 |
| Wang, GS | 1 |
| Monte, A | 1 |
| Bagdure, D | 1 |
| Heard, K | 1 |
| KIRSH, MM | 1 |
| ABRAMS, B | 1 |
| COON, W | 1 |
| ZUIDEMA, G | 1 |
3 other studies available for diphenhydramine and Hepatic Encephalopathy
| Article | Year |
|---|---|
MRI findings associated with acute liver failure.
Topics: Acetaminophen; Adult; Analgesics, Non-Narcotic; Brain; Brain Edema; Coma; Diphenhydramine; Hepatic E | 2009 |
Hepatic failure despite early acetylcysteine following large acetaminophen-diphenhydramine overdose.
Topics: Acetaminophen; Acetylcysteine; Alanine Transaminase; Analgesics, Non-Narcotic; Child; Cholinergic An | 2011 |
DIPHENHYDRAMINE (BENADRYL) HYDROCHLORIDE IN THE TREATMENT OF AMMONIA INTOXICATION.
Topics: Amino Acids; Ammonia; Animals; Blood; Blood Urea Nitrogen; Diphenhydramine; Dogs; Hepatic Encephalop | 1965 |