diphenhydramine has been researched along with Endotoxin Shock in 10 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
| Excerpt | Relevance | Reference |
|---|---|---|
| "This study was designed to use the H2 antagonist cimetidine and the H1 antagonist diphenhydramine alone and in combination to clarify the role of histamine in the development of endotoxin shock." | 3.67 | The effects of H1 and H2 histamine receptor antagonists on the development of endotoxemia in the conscious, unrestrained rat. ( Brackett, DJ; Schaefer, CF; Wilson, MF, 1985) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 7 (70.00) | 18.7374 |
| 1990's | 3 (30.00) | 18.2507 |
| 2000's | 0 (0.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| KALAS, JP | 1 |
| JACOBSON, ED | 1 |
| VICK, JA | 1 |
| Ick, JA | 1 |
| Bond, RF | 1 |
| Vildibill, HD | 1 |
| Krech, LH | 1 |
| Hershey, JC | 1 |
| Byrne, K | 2 |
| Sielaff, TD | 2 |
| Michna, B | 1 |
| Carey, PD | 2 |
| Blocher, CR | 2 |
| Vasquez, A | 2 |
| Sugerman, HJ | 2 |
| Tatum, JL | 1 |
| Hirsh, JI | 1 |
| Brackett, DJ | 1 |
| Schaefer, CF | 1 |
| Wilson, MF | 1 |
| Shenkman, BZ | 1 |
| Lish, PM | 1 |
| Robbins, SI | 1 |
| Peters, EL | 1 |
| Martin, DS | 1 |
| Kurzweg, FT | 1 |
| Amor, RL | 1 |
| Harvey, R | 1 |
| Daigle, L | 1 |
10 other studies available for diphenhydramine and Endotoxin Shock
| Article | Year |
|---|---|
THE EFFECT OF VASOACTIVE ANTAGONISTS IN ENDOTOXIN SHOCK.
Topics: Animals; Atropine; Blood Circulation; Blood Pressure; Blood Pressure Determination; Chloralose; Cypr | 1964 |
TRIGGER MECHANISM OF ENDOTOXIN SHOCK.
Topics: Atropine; Blood; Blood Platelets; Cerebrospinal Fluid; Dextrans; Diphenhydramine; Dogs; Endotoxins; | 1964 |
BIOASSAY OF THE PROMINENT HUMORAL AGENTS INVOLVED IN ENDOTOXIN SHOCK.
Topics: Adrenalectomy; Biological Assay; Blood Pressure; Blood Pressure Determination; Diphenhydramine; Dogs | 1965 |
Influence of histaminergic receptors on denervated canine gracilis muscle vascular tone during endotoxemia.
Topics: Adenosine; Animals; Blood Pressure; Cimetidine; Diphenhydramine; Dogs; Endotoxins; Escherichia coli; | 1991 |
Increased survival time after delayed histamine and prostaglandin blockade in a porcine model of severe sepsis-induced lung injury.
Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Extravascular Lung Water; Hemodynam | 1990 |
Ranitidine compared to cimetidine in multiagent pharmacological treatment of porcine Pseudomonas ARDS.
Topics: Animals; Cimetidine; Diphenhydramine; Drug Therapy, Combination; Hemodynamics; Ibuprofen; Pseudomona | 1990 |
The effects of H1 and H2 histamine receptor antagonists on the development of endotoxemia in the conscious, unrestrained rat.
Topics: Analysis of Variance; Animals; Blood Gas Analysis; Blood Pressure; Cimetidine; Diphenhydramine; Enfl | 1985 |
[Effect of verapamil, cromoglycate and dimedrol on the survivability of mice in endotoxic shock].
Topics: Animals; Cromolyn Sodium; Diphenhydramine; Dose-Response Relationship, Drug; Drug Evaluation, Precli | 1987 |
Specificity of antihistamine drugs and involvement of the adrenergic system in histamine deaths in the guinea pig.
Topics: Adrenal Medulla; Aerosols; Amitriptyline; Animals; Chlorpheniramine; Chlorpromazine; Diphenhydramine | 1966 |
Multiantagonist and volume therapy for late endotoxin shock.
Topics: Acidosis; Aminocaproates; Animals; Aprotinin; Bicarbonates; Cyproheptadine; Diphenhydramine; Dogs; E | 1966 |