diphenhydramine has been researched along with Endotoxemia in 1 studies
Diphenhydramine: A histamine H1 antagonist used as an antiemetic, antitussive, for dermatoses and pruritus, for hypersensitivity reactions, as a hypnotic, an antiparkinson, and as an ingredient in common cold preparations. It has some undesired antimuscarinic and sedative effects.
diphenhydramine : An ether that is the benzhydryl ether of 2-(dimethylamino)ethanol. It is a H1-receptor antagonist used as a antipruritic and antitussive drug.
antitussive : An agent that suppresses cough. Antitussives have a central or a peripheral action on the cough reflex, or a combination of both. Compare with expectorants, which are considered to increase the volume of secretions in the respiratory tract, so facilitating their removal by ciliary action and coughing, and mucolytics, which decrease the viscosity of mucus, facilitating its removal by ciliary action and expectoration.
Endotoxemia: A condition characterized by the presence of ENDOTOXINS in the blood. On lysis, the outer cell wall of gram-negative bacteria enters the systemic circulation and initiates a pathophysiologic cascade of pro-inflammatory mediators.
| Excerpt | Relevance | Reference |
|---|---|---|
| "The leukocyte-independent microvascular damage during early endotoxemia cannot be inhibited efficiently by the H1-receptor antagonist diphenhydramine, indicating that histamine seems to play only a minor role in that pathophysiology." | 3.71 | Effects of histamine-1 receptor antagonism on leukocyte-independent plasma extravasation during endotoxemia. ( Bach, A; Jäger, M; Martin, E; Schmidt, H; Schmidt, W; Secchi, A; Walther, A, 2001) |
| Timeframe | Studies, this research(%) | All Research% |
|---|---|---|
| pre-1990 | 0 (0.00) | 18.7374 |
| 1990's | 0 (0.00) | 18.2507 |
| 2000's | 1 (100.00) | 29.6817 |
| 2010's | 0 (0.00) | 24.3611 |
| 2020's | 0 (0.00) | 2.80 |
| Authors | Studies |
|---|---|
| Walther, A | 1 |
| Jäger, M | 1 |
| Secchi, A | 1 |
| Schmidt, W | 1 |
| Bach, A | 1 |
| Martin, E | 1 |
| Schmidt, H | 1 |
1 other study available for diphenhydramine and Endotoxemia
| Article | Year |
|---|---|
Effects of histamine-1 receptor antagonism on leukocyte-independent plasma extravasation during endotoxemia.
Topics: Animals; Capillary Permeability; Cell Adhesion; Diphenhydramine; Endotoxemia; Histamine H1 Antagonis | 2001 |